For example, you can cut a huge gash and pull out most of the cytoplasm in Stentor and it will flow back in pubmed.ncbi.nlm.nih.gov/24378633/

Simultaneously a really nice portrait, time capsule, and economic manifesto. Mr. Grimes' accent is similar to ones I grew up around as a young boy in Jericho Vermont in the late 1970s. (Probably 5 dairy farms on our dirt road alone, back then; all gone now.) www.youtube.com/watch?v=rVja...

On the event of James Watson's death, I highly recommend this 2023 commentary from @matthewcobb.bsky.social and Nathaniel Comfort with crucial new insights into the discovery of the double helix. (And also check out Cobb's brand new biography of Francis Crick) www.nature.com/articles/d41...

That image is from 1961 and an idealization. Here is an actual trajectory of fixational eye movements. The dots are 2 ms apart. If a midget ganglion cell, with single-cone receptive field, fires at 100 Hz, then every spike reports about a different cone. How can we ever read anything?

In the spirit 👻 of Freaky Friday 🎃, here is a beautiful yet eery video of zebrafish retina development showing horizontal cells (🔵) finding their way out of the crowded amacrine (🟠) layer to settle beneath the photoreceptors. Happy #Halloween! 🎥: PhD student Rae Wong from the @nordenlab.bsky.social

Our paper is out! Take a look if you’re curious to see how we use expansion microscopy on diatoms ☺️ Very excited to keep using this!!

After 13 years in the US, I’ve made the difficult decision to leave. Having packed up everything and rethought about priorities, rather painstakingly, while I’m sad to leave the life I’ve made here, I’m also relieved that I won’t have to plan my life around immigration policies anymore.

What a time to be alive

Thank you so much @wellcometrust.bsky.social for supporting us to push the the limits of #X-ray #nanoimaging and #connectomics, and to make technology more broadly available to the scientific community! 🙏

Nice visualization. Maximize for full effect.

Edward Kravitz, a Harvard biochemist who proved GABA's inhibitory power, passed away last month. He will "be remembered for his humanity, for his social conscience and his desire to help those less fortunate than he,” says Ronald Harris-Warrick. By @claudia-lopez.bsky.social bit.ly/479Ggmo

“Cellular Olympics” our catalog of freeky ultra fast cellular superhero’s is freely available “Ann Rev of microbiology” www.annualreviews.org/content/jour... This is a compilation of world’s fastest single cell organisms - enjoy this buffet of rare delightful protists with mind bending speeds. 🧪

New preprint from the lab: A reference brain for the clonal raider ant. With this resource, which is based on 40 individual brains, you can register and compare all kinds of samples in a common space. It comes with lots of detailed protocols and a user-friendly GUI. www.biorxiv.org/content/10.1...

Ingenious concept - light sheet on serial sections by photo-etching the expanded hydrogel, layer by layer. Photo-sectioning is quite slow, and the volumetric images are insanely large and complex, but the data look wonderful. www.science.org/doi/10.1126/...

Final version of our paper on ciliary metachronal waves out now in Science Advances! doi.org/10.1126/scia... This is the main thesis work of my PhD student Rebecca Poon, who caught many #platnereis larvae and tirelessly ablated them with a laser. THREAD

Excited to share our new #biorxivpreprint: “Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1... We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10

And he's off! Well-deserved. :)

That's what we're saying people should try to do here: www.sciencedirect.com/science/arti...

Interesting answer from Mark to a question I had about his piece on recurrence and active filtering in sensory cortex (at www.annualreviews.org/content/jour...)

Our group at the Allen Institute is recruiting a technician and postdoc to work on light microscopy-based connectomics. Please DM me or share with anyone you think may be interested in this NIH BRAIN CONNECTS funded project.

I love this piece! It shows the many ways a connectome can be put to use, AND the many complementary modalities that are needed, beyond the connectome, to answer real questions. And it makes me feel good about having helped to generate the thing. :)

Rendering this video was a nice test for #Blender3d, as the full set of bodies visible by the end involved almost 1.1 billion polygons. It all worked out well on our H200 cluster.

Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....

📣 We’re hiring, please RT! Fully funded 4-year PhD position in our CVPD group at @informatikaehu.bsky.social! Research at the intersection of AI, deep learning & bioimage analysis. 🧠🔬 📅 Applications open Oct 6 (deadline: ~Oct 27) 📍 San Sebastian, Spain. 👉 cvpd.github.io/post/2025-09...

Case Western Reserve Department of Biology is hiring! We're recruiting for a tenure-track position focusing on eukaryotic microbiology, especially microbial/environment interactions. Please share widely: apply.interfolio.com/174456

I am so happy this perspective was published today, on Thanksgiving day!! 🥂🦃 I reflect on how keeping in touch with a field I left behind long ago continues to bring me joy and fulfillment.

Our new preprint!: arxiv.org/abs/2509.18399 Imaging fast glutamate or voltage sensors? New method to amplify electro-optical deflectors enables MHz line rate imaging. No new laser required. Led by @clwarkentin.bsky.social & @hari-shankar.bsky.social. MHz random-access imaging is in the works…

Ed Kravitz passed away yesterday. He was a remarkable scientist and mentor- brilliant, curious, creative, and kind. I am grateful to have learned from him. His legacy will endure through his science and through the many people he inspired. We will miss you, Ed.

Per NSF staff, the solicitation was cleared in the system, and should have posted automatically on the next business day. So it is being manually held—there's not some kind of logistical issue. Unclear what the rationale for this is.

I don't know that it works perfectly, but I have to say that the Asta search tool from @ai2.bsky.social is exactly what I want from an AI-powered research search tool for scientists: Describe a style of experiment or work and see if there are papers that have done that. asta.allen.ai/chat

Do you know what happens when you touch a carnivorous sundew plant? If the touch is strong and large enough, a cytosolic calcium wave will spread from the site of touch throughout the whole plant, but if you only touch one tentacle (see post below), the calcium wave will be local and less intense.

lovely whole-cell reconstructions of recorded cells using juxtacellular neurobiotin fill

Whoa - neuronal ciliary proteome! Tons to dig into here - different from kidney cilia proteome (perhaps unsurprising) and enriched for many postsynaptic proteins, strengthening previous suggestions of cilia as postsynaptic signaling structures. @nachury.bsky.social www.biorxiv.org/content/10.1...

🪰 How do dozens of tiny fly muscles cooperate to move a leg? We’re excited to share the first 3D, data-driven musculoskeletal model of Drosophila legs based on Hill-type muscles, running in OpenSim and MuJoCo simulation environments. Preprint: arxiv.org/abs/2509.06426

Come to the MBL in Woods Hole @mblscience.bsky.social for a GRASS FELLOWSHIP @grassfoundation.bsky.social 🦑 🐙🐛 There are two application deadlines this year: Oct 15, 2025 (submit by then to receive feedback on your application!), and Dec 1, 2025 (final deadline). grassfoundation.org/application-...

Brain stimulation without causing tissue damage or electrode damage. The most common approach to stimulating CNS tissue without causing tissue damage is the "Shannon limit". Shannon, R.V., 2002. A model of safe levels for electrical stimulation. 1/

A good read in the current moment (and evergreen). Peter Sterling is a pioneer of volume electron microscopy of neuronal circuits and was a Freedom Rider. www.cell.com/current-biol...

🚨 We’re hiring a postdoc! 🚨 Excited for our new NiCE grant with @lauerlab.bsky.social @batwoman123.bsky.social 🎉We use a comparative approach, two-photon imaging & optogenetics to identify why bats🦇 and deer mice resist noise but lab mice don't. If you're interested, please DM or e-mail me!

We are looking for an IT engineer with a focus on operations and research data management at the Centre for Organismal Studies at @uniheidelberg in Heidelberg, Germany #IT #sysadmin #linux #ResearchData please help to spread this opening […] [Original post on biologists.social]

We're happy to announce the 2025 International OME-NGFF workshop 🎉 📅 Dates: - Symposium: Nov 10–11, 2025 - Hackathon: Nov 12–14, 2025 📍 Location: Zurich, Switzerland Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...  #bioimaging #openscience #OMENGFF #OMEZarr (1/x 🧵)

At long last, the version of record of our paper on the #platynereis #connectome "Whole-body connectome of a segmented annelid larva" is out. Explore the rich online presentation with all the videos, figures and source data here: https://doi.org/10.7554/eLife.97964 @eLife @biology […]

We are recruiting 2 postdocs to work on bacterial motility using a combination of cryoEM, FLM and MD. An exciting collaboration with Kirsty Wan @micromotility.bsky.social Wolfram Moebius @wolframmoebius.bsky.social and Daniel Kattnig. Please see links in the thread below!

Better ML for cryo-ET starts with better benchmarks. We built a phantom cryo-ET dataset (~500 tomograms) + hosted a Kaggle challenge. The result: community models beat expert tools. Read more in the @natmethods.nature.com article that just came out: 🔗 doi.org/10.1038/s415...

You had me at "supergiant cannibals." 😱 Gotta love the world of ciliates. Good🧵⬇️

The list of successfully fixed species keeps getting longer and longer. Can’t wait for the first #UExM images fresh out of our new scopes… Amazing job @fmikus.bsky.social and thanks @pjkeelinglab.bsky.social, @fburki.bsky.social, Denis, Vittorio and all for joining forces !

Today, I would like to honor the memory of Roger Y. Tsien, who died on August 24, 2016. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more! #FluorescenceFriday www.nature.com/articles/nme...

Want to help us image and understand those incredible samples Felix just collected at UBC - and many more? 2 more days to apply! embl.wd103.myworkdayjobs.com/en-US/EMBL/j... #ExM #PlanetaryCellBiology 🧪🧬🔬🌍🌱🦠

Neuronal diversity is written in transcriptional codes 🧬. But what is the logic of these codes that define cell types and wiring patterns? To find out we built a #scRNAseq developmental atlas of the Drosophila nerve cord and linked it to the #connectome 🪰🧠 #preprint thread ⬇️1/8

agree w davi. we can operantly condition an adult fly to control a cursor with motor neuron firing rates (paper in prep), but a fly is not going to reach an equivalent level of dexterity with totally new effectors. might be more plastic if you could hook it up during metamorphosis.

Over a decade after reading it, I think about this Neil Young profile at least 1-2x/mo. especially this quote. www.nytimes.com/2012/09/23/m...