Ed Kravitz passed away yesterday. He was a remarkable scientist and mentor- brilliant, curious, creative, and kind. I am grateful to have learned from him. His legacy will endure through his science and through the many people he inspired. We will miss you, Ed.

Per NSF staff, the solicitation was cleared in the system, and should have posted automatically on the next business day. So it is being manually held—there's not some kind of logistical issue. Unclear what the rationale for this is.

I don't know that it works perfectly, but I have to say that the Asta search tool from @ai2.bsky.social is exactly what I want from an AI-powered research search tool for scientists: Describe a style of experiment or work and see if there are papers that have done that. asta.allen.ai/chat

Do you know what happens when you touch a carnivorous sundew plant? If the touch is strong and large enough, a cytosolic calcium wave will spread from the site of touch throughout the whole plant, but if you only touch one tentacle (see post below), the calcium wave will be local and less intense.

lovely whole-cell reconstructions of recorded cells using juxtacellular neurobiotin fill

Whoa - neuronal ciliary proteome! Tons to dig into here - different from kidney cilia proteome (perhaps unsurprising) and enriched for many postsynaptic proteins, strengthening previous suggestions of cilia as postsynaptic signaling structures. @nachury.bsky.social www.biorxiv.org/content/10.1...

🪰 How do dozens of tiny fly muscles cooperate to move a leg? We’re excited to share the first 3D, data-driven musculoskeletal model of Drosophila legs based on Hill-type muscles, running in OpenSim and MuJoCo simulation environments. Preprint: arxiv.org/abs/2509.06426

Come to the MBL in Woods Hole @mblscience.bsky.social for a GRASS FELLOWSHIP @grassfoundation.bsky.social 🦑 🐙🐛 There are two application deadlines this year: Oct 15, 2025 (submit by then to receive feedback on your application!), and Dec 1, 2025 (final deadline). grassfoundation.org/application-...

Brain stimulation without causing tissue damage or electrode damage. The most common approach to stimulating CNS tissue without causing tissue damage is the "Shannon limit". Shannon, R.V., 2002. A model of safe levels for electrical stimulation. 1/

A good read in the current moment (and evergreen). Peter Sterling is a pioneer of volume electron microscopy of neuronal circuits and was a Freedom Rider. www.cell.com/current-biol...

🚨 We’re hiring a postdoc! 🚨 Excited for our new NiCE grant with @lauerlab.bsky.social @batwoman123.bsky.social 🎉We use a comparative approach, two-photon imaging & optogenetics to identify why bats🦇 and deer mice resist noise but lab mice don't. If you're interested, please DM or e-mail me!

We are looking for an IT engineer with a focus on operations and research data management at the Centre for Organismal Studies at @uniheidelberg in Heidelberg, Germany #IT #sysadmin #linux #ResearchData please help to spread this opening […] [Original post on biologists.social]

We're happy to announce the 2025 International OME-NGFF workshop 🎉 📅 Dates: - Symposium: Nov 10–11, 2025 - Hackathon: Nov 12–14, 2025 📍 Location: Zurich, Switzerland Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...  #bioimaging #openscience #OMENGFF #OMEZarr (1/x 🧵)

At long last, the version of record of our paper on the #platynereis #connectome "Whole-body connectome of a segmented annelid larva" is out. Explore the rich online presentation with all the videos, figures and source data here: https://doi.org/10.7554/eLife.97964 @eLife @biology […]

We are recruiting 2 postdocs to work on bacterial motility using a combination of cryoEM, FLM and MD. An exciting collaboration with Kirsty Wan @micromotility.bsky.social Wolfram Moebius @wolframmoebius.bsky.social and Daniel Kattnig. Please see links in the thread below!

Better ML for cryo-ET starts with better benchmarks. We built a phantom cryo-ET dataset (~500 tomograms) + hosted a Kaggle challenge. The result: community models beat expert tools. Read more in the @natmethods.nature.com article that just came out: 🔗 doi.org/10.1038/s415...

You had me at "supergiant cannibals." 😱 Gotta love the world of ciliates. Good🧵⬇️

The list of successfully fixed species keeps getting longer and longer. Can’t wait for the first #UExM images fresh out of our new scopes… Amazing job @fmikus.bsky.social and thanks @pjkeelinglab.bsky.social, @fburki.bsky.social, Denis, Vittorio and all for joining forces !

Today, I would like to honor the memory of Roger Y. Tsien, who died on August 24, 2016. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more! #FluorescenceFriday www.nature.com/articles/nme...

Want to help us image and understand those incredible samples Felix just collected at UBC - and many more? 2 more days to apply! embl.wd103.myworkdayjobs.com/en-US/EMBL/j... #ExM #PlanetaryCellBiology 🧪🧬🔬🌍🌱🦠

Neuronal diversity is written in transcriptional codes 🧬. But what is the logic of these codes that define cell types and wiring patterns? To find out we built a #scRNAseq developmental atlas of the Drosophila nerve cord and linked it to the #connectome 🪰🧠 #preprint thread ⬇️1/8

agree w davi. we can operantly condition an adult fly to control a cursor with motor neuron firing rates (paper in prep), but a fly is not going to reach an equivalent level of dexterity with totally new effectors. might be more plastic if you could hook it up during metamorphosis.

Over a decade after reading it, I think about this Neil Young profile at least 1-2x/mo. especially this quote. www.nytimes.com/2012/09/23/m...

It was a good experience to step back and briefly take stock of the amazing progress in connectomics since I started working on this stuff (20 years ago!) thanks as well to @natrevneuro.nature.com for the constructive editorial interactions.

Another example of autonomous activity of different branches/compartments of fly neuronal arbors -- "integrate and fire" is a pleasant approximation...

So you think you understand everything about #Chlamydomonas photoresponses? think again! #protists #behaviour #cilia To explain how Chlamy switches handedness from swimming in CCW circles in low-light to CW in high-light... see our new preprint led by Alan Tsang (HKU) 👇 doi.org/10.1101/2025...

A big blow to All of Science, not just Harvard, not just the Fly community, not just Genetics. All of Science. Turbocharge was just switched off. Flies gave us so many insights.

Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you! embl.wd103.myworkdayjobs.com/en-US/EMBL/j... With @dudinlab.bsky.social @embl.org @biology-unige.bsky.social @moorefound.bsky.social

We have a postdoc opening for a protistologist with biophysics inclinations to join our @hfspo.bsky.social project! (focus will be on characterising the morphology, ultrastructure and behaviour of excavates) #protistsonsky Apply by Sept 17th (RTs appreciated!) jobs.exeter.ac.uk/hrpr_webrecr...

Good read.

Want to use the massive MICrONS dataset for your own research? We understand the challenges and we are here to support you. Submit your proposals for our Proofreading and Annotation program: Virtual Observatory of the Cortex (VORTEX) by August 15. microns-explorer.org/vortex

With @megyounger.bsky.social's lab, et al., we present the first connectomics work in the disease-vector mosquito Aedes aegypti, revealing how its brain is wired to detect host cues. Preprint: doi.org/10.1101/2025... #Neuroscience #Connectomics #vEM #VectorBiology 🧪

... curious to see if this one weird trick to recoup tariffs on scientific equipment actually works! tl;dr the UN Florence agreement says that scientific equipment (under certain conditions) may enter free of duty www.trade.gov/statutory-im...

I think the "embodiment" of this connectome is going to be such a hit: For instance take the interactive "body part" maps on Codex, where you can simply click on your favorite external or visceral part and it will show you all of the neurons associated it! codex.flywire.ai/app/body_par...

New preprint from @darbly.bsky.social‬ @briandepasquale.bsky.social‬ and my labs! If you love (or hate) mosquitoes, have a look: doi.org/10.1101/2025... We used TEM to describe the circuitry used for CO2 detection by mosquitoes. As usual with mosquitoes, nothing is as expected! 🌬️🦟

Happy to share our publication - Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution www.science.org/doi/10.1126/...

Preprint Alert! Walking mostly feels natural and easy to us - but the neuronal control of walking is actually incredibly complex. We leveraged the fruit fly as a genetically tractable animal model with a compact nervous system to ask how the brain controls walking direction: tinyurl.com/flywalk. 🧵..

What does a neural network look like? Maybe like this view of Larissa Heinrich's U-net for organelle segmentation, with edges between layer inputs and outputs. Want to help build networks like this? Join #HHMIJanelia's new AI initiative as a data engineer: hhmi.wd1.myworkdayjobs.com/en-US/Extern...

🧠 Excited by synapse-level brain mapping? Join us at a world-class institute to build molecular tools based on our new #LICONN work — and push the frontier of #MolecularConnectomics. Let’s decode the brain, one synapse at a time. hhmi.wd1.myworkdayjobs.com/en-US/Extern...

“The connectome shows that LT52 is anatomically positioned to inhibit the neural networks involved in steering toward a visual object in the environment. Thus, we suggest that LT52 functions to prevent the fly from steering toward its own leg.” nice 😁

Happy to be involved in UNICIL, our new Wellcome Trust Discovery project coordinated by @micromotility.bsky.social We will study ciliary dynamics across scales and organisms. A long-term #postdoc position will be available at Heidelberg University […] [Original post on biologists.social]

Go Zhihao! 😄 High quality ultrastructure and imaging in this dataset. Well done.

Excited to share a connectomics dataset of hippocampus CA3. Explore the dataset: pyr.ai Paper introducing the dataset and some of our discoveries: www.biorxiv.org/content/10.1...

During the subcommittee markup of the Commerce, Justice, Science, and Related Agencies, Sen. Jerry Moran (R-KS) announced that the bill contains 33.9 billion for science agencies (NASA & NSF) which would keep funding steady. ~8 min mark. Full meeting tomorrow.

keeping my eye on this Senate committee meeting tomorrow, which will AFAIK will be congress's first response to White House's proposed ~60% NSF budget cut: www.appropriations.senate.gov/hearings/ful...

🚨 SAVE THE DATE 🚨 Inaugural CCP-volumeEM Community Meeting, 3rd November 2025 at @crick.ac.uk in London "Towards a collaborative computational community for volume EM" Timings: 12pm - 5.30pm, followed by networking reception #volumeEM #BioImageAnalysis #VEM #CCPvolumeEM #CoSeC

A scalable, all-optical method for mapping synaptic connectivity with cell-type specificity https://www.biorxiv.org/content/10.1101/2025.06.25.661552v1

Help us record firefly flashes! 👇🙏

NEW: NSF will be kicked out of their building. Announcement will be made tomorrow by HUD Sec. and Governor of VA. HUD will take over the NSF building over the next two years. NSF staffer: "There is no planning for NSF, no identified future location, appropriation for a new building or a move."