Version of Record Structural basis for mTORC1 activation on the lysosomal membrane www.nature.com/articles/s41...

🚨🧠🔬 A major breakthrough in molecular neuroscience: I am excited to share a new story from our lab, published in accelerated format today by @nature.com: "Delta-type glutamate receptors are ligand-gated ion channels" Read more here (free article link): rdcu.be/eGIKz

Quite a week for #lipidtime: phenomenal study using bifunctional lipid probes to quantify intracellular lipid transport from @nadlerlab.bsky.social and colleagues is now out @nature.com! www.nature.com/articles/s41...

Very excited to announce that my first, first author paper, is now on BioRxiv! In this paper we unambiguously show #COPII coated vesicles in unperturbed human cells for the very first time!! Make my day and check it out! www.biorxiv.org/content/10.1... #Cryo-ET #TeamTomo #Cryo-CLEM ❄️🔬❄️🔬❄️🔬❄️🔬

This was a fun paper to be involved in. Carlos identified many known and unknown proteins associated with endosomal membrane domains with really amazing proximity proteomics. @carlosantonplagaro.bsky.social @peterjcullen1.bsky.social

I am excited to share our latest preprint presenting the structure of human NHE6, a key endosomal Na⁺/H⁺ exchanger involved in Christianson syndrome. We bring together #cryo-EM, NMR, SAXS, lipidomics, and functional assays for an integrative analysis of NHE6 architecture, function, and regulation.

Excellent work from the lab of Ben Engel.

Arrayed CRISPR/Cas9 Loss-Of-Function Screen in a Neuronal Model of Adaptor Protein Complex 4 Deficiency Identifies Modulators of ATG9A Trafficking https://www.biorxiv.org/content/10.1101/2025.02.22.639634v1

Excited to present our new story in Science Advances at #bps2025 meeting next week. Thanks to Vanderbilt CSB for featuring our work! www.vanderbilt.edu/csb/2025/02/...

New work from the @lpjacksonlab.bsky.social uses a combination of biochemical, biophysical and computational modeling techniques to investigate endosomal trafficking players. Congrats to 1st author @mintuju.bsky.social! bit.ly/4hYry4o @vubasicsciences.bsky.social @vandybiomed.bsky.social

Thrilled to have my first-author publication in Science Advances, and grateful to my supervisor for sharing it on Bluesky! This marks a major milestone in our journey to unravel the complexities of endosomal protein interactions!

The Jackson lab is thrilled to join Bluesky and find so many friends, scientists, and colleagues. It is an uncertain and frankly scary time for U.S. science, but today we are pausing to celebrate an exciting new paper in Science Advances: www.science.org/doi/10.1126/.... (Thread)