New work from @acovarrubias.bsky.social at @dgsomucla.bsky.social highlights how “zombie” immune cells in the liver build up w/ age & drive chronic inflammation. Powerful example of training, discovery & collaboration advancing our understanding of aging. nature.com/articles/s43587-026-01101-6

For #FluorescenceFriday, an E10 embryo showing Pax2 localization. #DevelopmentalBiology

I'll be recruiting grad students and postdocs, so please reach out if interested! More details here: sites.google.com/view/marcust... @uclaneurotheme.bsky.social @dgsomucla.bsky.social

And here’s the eclipse photo from Artemis II. I am in tears.

There is color out there on the moon. Check out a simple linear stretch of the OG image showing the different composition of the lunar surface, particularly in the maria. Holy smokes this is exciting.

Welcome to UCLA!!! 🔬✨

So breathtaking...

🚨📜Our new paper out in @AdvSciNews: ER shape matters for neuronal health - disrupting ER continuity halts neuro-firing as it slows Ca2+ store refill, explaining selective neuronal vulnerability to ER problems in neurodegeneration 🧠 a thread to follow advanced.onlinelibrary.wiley.com/doi/10.1002/...

All data in this work are beautiful – look at this 3-day timelapse of in vivo myelination along a zebrafish axon! www.nature.com/articles/s41...

I'm so pleased to see this work on neural crest development out in Nature today! This was a truly fantastic collaboration with @gleesonlab.bsky.social, Keng loi (Harry) Vong and @xiaoxuyang.bsky.social. Huge thanks to everyone involved 👏 🧪🐣 #devbio www.nature.com/articles/s41...

Happy #FluorescenceFriday! This is a confocal 🔬 series of a developing 🐭 spinal cord showing nuclei, actin, and cellular membrane stains colored in 🌈 Microscopy by postdoc @christinaadaly.bsky.social 👩‍🔬 🧪

#neuroscience #trainees One month left to nominate an outstanding mentor for the NINDS Landis Award! Nomination form here: forms.cloud.microsoft/pages/respon...

If you can't make the UCLA Brain Health Summit in person, the meeting will be live-streamed on Youtube here: teams.semel.ucla.edu/longevity/ev... (click on the hyperlink in the top right corner of the program).

Extremely timely science led by the Hong Lab @UCLA!

Dear Devoted Users of SeqSeek, I’m sorry, but NIH has decided that we can no longer maintain the website. All of the data is still available at the links provided, and the new platform even has added functionality. Happy gene expression hunting! seqseek.ninds.nih.gov

Using vDISCO tissue clearing, and a new ultrabright chemical labeling strategy. This work introduces LINCS for rapid, scalable 3D connectivity mapping from single neurons to whole brains, advances for high-throughput circuit mapping. Great work by Rui Lin lab. www.sciencedirect.com/science/arti...

Been under the weather fro a few days. It is wonderful to be able to see hummingbirds like this Anna's Hummingbird just by going out in my yard in #DavisCA. #birds

Timeline Cleanse 🐙

Check out the newest work from our, from Fabricio Nicola @fabricionicola.bsky.social on mouse jumping and spinal cell types. Excellent collab with @vulcnethologist.bsky.social www.biorxiv.org/content/10.6...

This is so exciting!! congratulations @droligo.bsky.social 🎉🎉

Happy Fluorescence Friday :-)

New paper from the lab led by @ericmulhall.bsky.social addresses how PIEZO1 and PIEZO2 are tuned to different types mechanical forces. From nanometer-scale super-resolution microscopy to in vivo experiments, links single-molecule observations to physiological function. www.nature.com/articles/s41...

Mercury was only 50 arcminutes (0.8°) above a very young waxing crescent Moon this evening. KAS member Pete Mumbower captured this image from his home in Vicksburg, MI.

As Fran was nice enough to highlight this, I thought I'd put up a brief thread. 3 in 10 proteins that our cells make are either embedded in membranes (ion channels, adhesion molecules, etc.) or secreted (insulin, antibodies). They move through the secretory pathway. 1/

BIG FIGHT AT POLAND’S WROCLAW ZOO!!!

your second moment of calm

We are hiring new faculty!! Come join our amazing community in the Department of Molecular Microbiology at Washington University School of Medicine! The deadline for applications is 2/21, but applications will be reviewed on a rolling basis. facultyopportunities.wustl.edu/Posting/Deta...

Thrilled to share our latest study, led by @reikatei.bsky.social, in @natchembio.nature.com! We began by asking a simple question—how do cells know if they have too much of a lipid in a particular membrane, and how do they respond to rectify this imbalance? www.nature.com/articles/s41... More info 👇

Holy cow the Zhou lab at UCLA is cooking with Isonet 2 - www.biorxiv.org/content/10.6... Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet

Huge shoutout to all the NIH scientific review officers and external academics who stepped up after the government shutdown to help reschedule hundreds of study sections. Thanks to this great community, my fellowship review was rescheduled within two months of its original review date 🧪

This--my SRO and her colleagues are doing heroic work AND keeping me informed--THANK YOU!

Thrilled to share our new paper! With @tomtom-auer.bsky.social team, we asked how #evolution reshapes what animals #eat to match their ecological niches. Using pan-neuronal Ca2+ imaging, we show that the changes are in how the brain processes #taste. Link @nature.com: www.nature.com/articles/s41...

@drugmonkey.bsky.social timely.

How is the persistence of compartmentalized inflammation sustained in MS? Our new study in @cp-immunity.bsky.social offers some hints. cell.com/immunity/ful... Thanks and congratulations to all contributors

New tenure track faculty position in glia and/or neurovascular coupling! Please come join us! academicjobsonline.org/ajo/jobs/30864 #neurosky #neuroskyence #glia #neurojobs

It’s so exciting to see this. These tools will be game changing.

If you think your field needs a collection of curated reviews and protocols, let me know! Let's create it and help the community.

Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years? A 30-year long mystery unraveled @ScienceMagazine today! Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation www.science.org/doi/10.1126/...

The first (of hopefully many) reports to come from our collaboration with @hjp.bsky.social We present a new type of cell fitness assay that allows you to both quantify and explain differences across human donors in cell proliferation and sensitivity to environmental toxicants.

Wow! This is really exciting!

UCLA research is amazing ✨✨ newsroom.ucla.edu/stories/ucla...

🚨 New Preprint! Ex-dSTORM resolves fine details of the molecular architecture of CCPs, the 8-nm periodicity of microtubules, and the docking site of synaptic vesicles at the presynapse of hippocampal neurons. ▶️ www.biorxiv.org/content/10.1...

It was great to co-teach today’s Academic Skills workshop with the amazing @debiaselm.bsky.social 🧪✨

Check out our recent progress using 🧬 PAINT kinetics to decode molecular tension in super-resolution force imaging! 🔬 Great team effort from Seongho, Adam, Irving, and Kevin! 👏 #DNA-PAINT #tension #integrin #superresolution #adhesion doi.org/10.1002/advs...

Please spread the word about the glia networks world-wide 🙃 @astrocytenet.bsky.social @astrocytecafe.bsky.social @ukglia.bsky.social @glialclub.bsky.social @gliameeting.bsky.social @warsawgliacomm.bsky.social @italianglianetwork.bsky.social @canglia.bsky.social

Come join our lab as Postdoctoral Fellow! The project will investigate the maturation of spinal circuits and their plasticity within chronic widespread pain states. Apply here: www.ucl.ac.uk/work-at-ucl/... until 11th April. @ucllifesciences.bsky.social @uclnpp.bsky.social @jobrxiv.bsky.social

It was a pleasure hosting Ritchie Ho for this weeks Neural Repair seminar and hearing about his amazing work to understand pathogenic mechanisms of ALS @ucla @ritchieholab.bsky.social