Pretty tired from a 12km loop yesterday from highland base camp to Hveradalir in Kerlingarfjöll. Worth the pain, though.

Full professor complaining to an assistant professor on how hard it is to get funding nowadays

This will devastate all of my colleagues that do neuroscience in mice. Drugs don't always translate from mouse to human, But 90% of our genes are shared. They allow recordings and manipulations that cannot be done in humans. We will cede discovery to Europe and China with this unnecessary handicap.

must be incredibly frustrating and disheartening to have federal funding that was promised to you for important work suddenly and arbitrarily ripped away

UK neuroscience graduates! PhD opportunity here at Glasgow SPN: www.findaphd.com/phds/project... Closing date July 4

In late January, I said we were "still exploring" a cool thing we found in RN. Well, we're back, and we've got movement kinematics (thanks to ‪@deeplabcut.bsky.social‬)! (You can find all the details in our updated bioRxiv paper, linked below) www.biorxiv.org/content/10.1...

Large-scale projects run the risk of stifling scientific independence. Instead, let’s explore alternative mechanisms of collaboration, writes @neuralreckoning.bsky.social. #neuroskyence www.thetransmitter.org/funding/neur...

It is beyond disturbing when the NIH and HHS Directors do not understand that animal models are essential in research www.statnews.com/2025/05/19/a...

Excited to share my PhD paper! In it, we use targeted 2-photon optogenetic stimulation to determine how V1 activity is read-out in a detection task. We found that network influence, not visual coding properties, predicted the impact of ensembles on behavior - contradicting our expectations (1/5).

Bilateral integration in somatosensory cortex is controlled by behavioral relevance 🧠🧪 @scottrpluta.bsky.social www.nature.com/articles/s41...

I'm really proud of my two graduate students, Hyein and Hayagreev, for getting this challenging and exciting project across the finish line. We reveal the state-dependent logic that underlies callosal signaling between the somatosensory cortices. www.nature.com/articles/s41...

The Oldenburg lab is looking for another postdoc! If you want to use holographic optogenetics to answer questions about neural codes let me know. We like shooting lasers and thinking about movement. We're located at Rutgers in Piscataway NJ (its like ~45 min from NYC). oldenburglab.com/positions/

May 2021, shortly after we finished building automated boxes for training mice to perform bilateral discrimination using active touch. The first paper is finally dropping soon.

Our latest editorial in defense of vaccines and vaccination, introduces two Perspectives in this issue on priorities for outbreak vaccination, as well as the important successes of vaccines to date Please read and spread the word 🙏🏻!

New results! Evidence for an active handoff between cerebral hemispheres during target tracking www.biorxiv.org/content/10.1... #neuroscience

Thrilled that our paper has been published in @elife.bsky.social doi.org/10.7554/eLif... We ask: how can a neuron integrate information across multiple time scales? Twist: This neuron has extreme properties that helps it work ~300x times faster than neurons in the hippocampus Summary 🧵to follow

My lab @kinshiplab.bsky.social is recruiting a postdoc 🚨 with Sept start date Preference for in-vivo ephys / circuits experience / interest in applying quantitative methods to natural social behaviour. Funding & visa fees for 1-yr with possible extension. Send me your CV & visit kinshiplab.org

Our new paper is out in Science. What is the synaptic plasticity rule in the brain, we asked. It turns out there are multiple, even within individual neurons. Congrats Jake! www.science.org/doi/10.1126/...

(Plz repost) I’ve been receiving some good news lately and will be hiring at all levels to expand the lab. Please get in contact if you are interested in reinforcement learning, neural plasticity, neural circuit dynamics, and/or hearing rehabilitation. pierre.apostolides @ umich .edu Tyvm

Thrilled to see this part of my PhD work with @rcbagot.bsky.social now out in @natcomms.nature.com! (1/14) www.nature.com/articles/s41...

Neurons just keep mixing their selectivity. Whisking and locomotion are jointly represented in superior colliculus neurons journals.plos.org/plosbiology/... #neuroscience

It brings me real satisfaction to see this long overdue piece in the whisker system puzzle come to fruition. Suma Chinta's implementation of the LNP model was incredible. After seeing this data for 3+ years now, it still amazes me how well SC neurons predict movements - past, present, and future! 🐭

Yes, we were surprised to discover that the sensory map in superior colliculus (SC) is biased by stimulus value, while the map in cortex maintained a faithful representation of receptor space. Bias in the SC map emerged only when the sensory associations had opposite values. Check out the paper!

Across the neural hierarchy, sensory maps are thought to transition from a faithful representation of receptor space to a map weighted by learned associations. Where does this transformation occur? In our latest paper, we explore a value-based spatial transformation between cortex and midbrain.

Compelling pushback from @jmgrohneuro.bsky.social and the Board of Scientific Counselors at the National Institute on Mental Health (NIMH) regarding termination of tenure-track investigators driven by DOGE. 1/2

This is an attempt to criminalize free speech and suppress dissent. If we don’t take a strong stand against this, it’s the end of our democracy, and not just higher education. Universities are the trial balloon, but it doesn’t end here. Next, it will be employers, cities and towns, and individuals.

I'm hiring a full-time research technician to work in my lab at Nathan Kline. Benefits included! Some lab experience preferred... experience with mouse surgeries a huge plus. If you live in NYC, there are two daily shuttles that take ≈20 min from upper manhattan. nki.applicantpro.com/jobs/3663631

The NIH intramural program is a unparalleled in both its ability to do bleeding edge science and train the next generation of scientists. Not renewing Title 42 employees is hellacious. www.science.org/content/arti...

WE JUST GOT DOGE’D no funding for this year. We have to cancel the program and email 450 applicants there will be no REU program in physics at MSU. First time in 20+ years. I’m fucking livid, y’all.

Just learned that the Sensorimotor Neuroscience (SMN) study section is postponed indefinitely. Over 100 proposals to understand and treat sensorimotor diseases that will not be evaluated or funded. Thousands of hours wasted by writers and reviewers. All due to the Republican block on NIH operation.

Such bad news.

In case you were wondering how Fox News is covering the proposed cuts at the NIH:

I had two grant proposals up for review in the NIH Bacterial Virulence (BV) study section. It was canceled without notice this morning. Without those grants, my lab must close within a year. And so the purge of scientific research in the US continues 🤬 #MicroSky 🦠🧫🧪🧬🔬

senator collins was not in the office this morning, but my mom left her this remarkable letter.

Petition to Reverse the NIH Indirect Cost Cap initiated by Tom Maniatis. Please amplify Sign the Petition: chng.it/kK2HMP5pGk "Share with Leadership & Faculty. Reach out to professional societies, biotech and pharma leaders, and philanthropic organizations to raise awareness and mobilize support."

I have one submitted that says we expect activity to be "biased" toward superficial cortical layers. We should have said it would pull itself up by the bootstraps to superficial layers on its own merit

First Post on Blue Sky promoting science from the group! Delighted for the first Neurodegeneration paper from my lab. Led by Hammad Khan and wonderful collaborators, we reveal cortical circuit biomarkers delineating the gradual progression of Lewy pathology across synucleinopathies rdcu.be/d5f3w

Great work from a talented team of scientists. Best of luck, Daniel.

Cutting it a bit fine, but here’s my review of the year in neuroscience for 2024 The eighth of these, would you believe? We’ve got dark neurons, tiny monkeys, the most complete brain wiring diagram ever constructed, and much more… Published on The Spike Enjoy! medium.com/the-spike/20...

If we believe that we have all the essential ideas, that what we need is not research but development, well okay. A giant project makes sense. But if we are still short several key ideas, this is a terrible idea because *we can’t scale our way to insight!* 6/n

There's a movement in neuroscience suggesting we should be pursuing bigger bets with larger teams. I think there's a case for doing a bit of this, but I think it's a bad idea to prioritise it for two reasons, and a good case for saying we should be moving in the exact opposite direction. 🧠🧪

OK If we are moving to Bluesky I am rescuing my favourite ever twitter thread (Jan 2019). The renamed: Bluesky-sized history of neuroscience (biased by my interests)