In his book “Helgoland,” the theoretical physicist Carlo Rovelli cites the Buddhist philosopher Nagarjuna as an influence on his work. “By renouncing ‘primary’ entities or any ‘ultimate absolute reality,’ we can better make sense of the world.” www.quantamagazine.org/carlo-rovell...

What If You Spent Every Waking Moment Taking On Elon Musk? www.nytimes.com/2025/10/31/b...

“The biggest lesson of the past two decades of Silicon Valley is that Meta, Amazon, and Google—and even the newer AI labs such as OpenAI—have remade our world and have become unfathomably rich for it, all while being mostly oblivious or uninterested in the fallout.” Worth a read!

“.. Staying on X when it has become so toxic and ungovernable suggests either weakness or complete naivety. We are living in a world of many malevolent geopolitical actors. Musk’s X is one such actor.” @drjennings.bsky.social @lorak.bsky.social observer.co.uk/news/opinion...

Just to be super clear, if you’re phoning in your peer review to ai you should quit your job so someone else who actually likes science can have it.

I told @davekarpf.bsky.social not to read Yudkowsky's awful new book. He didn't listen, but now you can all benefit from our shared misery. 😁

Is it 2007 all over again?

He Was Expected to Get Alzheimer’s 25 Years Ago. Why Hasn’t He? www.nytimes.com/2025/10/07/h...

Renewing my yearly bet on Cooper/Miller for the Nobels. One might think that I would learn after being wrong so many times, but one would be mistaken. laskerfoundation.org/winners/b-an...

Wonderful session yesterday! @cyrilpedia.bsky.social

RIP to Jane Goodall, who opened the world's eyes to our closest relatives. (Photo by NatGeo's Hugo Van Lawick)

This captures much of the frustration of today.

Dwarkesh gets schooled by Richard Sutton (Father of RL) on LLMs…! Obviouly, LLMs are not the way forward and their capabilities are hiting a wall. There is an AI bubble! @adambecker.bsky.social podcasts.apple.com/pt/podcast/d...

The Nobel Prize season is fast approaching. Here are my two top predictions/bets for Physiology or Medicine (what else? 😉) in 2025: 1. Zhijian Chen, Andrea Ablasser & Glen N. Barber for: "cGAS-STING pathway"; 2. Svetlana Mojsov, Joel Habener & @danieljdrucker.bsky.social for: " GLP-1-based drugs".

Harvard Dean Was Paid $150,000 as an Expert Witness in Tylenol Lawsuits www.nytimes.com/2025/09/23/h...

America is still out there, somewhere...: Jimmy Kimmel, Somber but Defiant, Defends Free Speech in Return to ABC www.nytimes.com/2025/09/23/b...

Brazil leading the way: Bolsonaro Sentenced to 27 Years in Prison for Plotting Coup in Brazil www.nytimes.com/2025/09/11/w...

Epigenetic silencing of interleukin-10 by host-derived oxidized phospholipids supports a lethal inflammatory response to infections: Immunity www.cell.com/immunity/ful...

'Big tech firms will get into bed with pretty much anyone willing to push back against regulation that threatens their business model, which thrives on the most extreme viral content. Silicon Valley’s sycophantic support of Donald Trump is a case in point.' www.ft.com/content/62b1...

"How Are the Very Rich Feeling About New York’s Next Mayor?" A Dramatic Reading of The Recent New York Times Dispatch from the Hamptons. Presented by The Gilded Age's Morgan Spector.

www.latimes.com/obituaries/s... RIP David Baltimore. A true giant of biomedical research. Made so many fundamental discoveries: Reverse transcriptase; NF-kB; Rag genes (among others) Also shut down his lab for a week in 1970 to protest the US invasion of Cambodia.

I am one of many hundreds of scientists that David generously mentored, supported, and inspired. His influence on each of us was deep and lasting, and his impact on the world immeasurable. Arguably David Baltimore is one of the greatest scientists of any generation.

Sad to learn one of the greatest has left us! “David fit into that culture of competitive smartness. He was the smartest of all.” David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87 www.nytimes.com/2025/09/07/s...

The billionaires funding aging reversal. When they were young they wanted to be rich. When they were rich, they wanted to be young. www.wsj.com/health/welln...

Great episode! podcasts.apple.com/pt/podcast/i...

#RFKJr has now lost the @nypost.com. His days as HHS Secretary are numbered. Keep up the pressure—let’s get him out the door. nypost.com/2025/09/04/o...

Simpering cowards one and all. This is almost unbearable to watch.

🖤🇵🇹 Portugal Mourns After Deadly Funicular Crash and Looks for Its Cause www.nytimes.com/2025/09/04/w...

Anthracyclines are fascinating and powerful drugs!

@harvard.edu gave an MD and a PhD to this moron! 😱 Florida Moves to End Vaccine Mandates for Schoolchildren www.nytimes.com/2025/09/03/u...

Results so stunningly clear they inspired this classic xkcd (xkcd.com/2400/):

I hope they nuke this demonic horseshit from orbit

🔮 New evidence for AI and the job market www.exponentialview.co/p/new-eviden...

Mob advocates have warned that if every truck company in the class action filed a claim, nothing would ever "fall outta the back of a truck in Brooklyn" again.

"La lenteur est le secret du bonheur !" @cyrilpedia.bsky.social www.youtube.com/watch?v=zoPR...

Wonderful review on the biology of interferons by @lozanzi.bsky.social! www.cell.com/cell/fulltex...

“I have a friend who told me: “This is my last round in my life because I have lung cancer”. But half a year later he came back and had just started the treatment we developed, and he was just completely cured.” Tasuku Honjo (1942- ) NobelPrize in Medicine 2018

I have to agree with Sam Altman: there is an AI bubble! open.substack.com/pub/garymarc...

The wait is over - AGI is here! 😂 @adambecker.bsky.social

Biological and Clinical Implications of a Model of Surveillance Immunity Katharina L. Willmann & @lferreiramoita.bsky.social review leading models of immune response initiation and put forward a model that incorporates detection of homeostasis deviation: buff.ly/6YAfZSU

Very happy to share our favorite model for immune response initiation! @jclinical-invest.bsky.social @reisesousalab.bsky.social @lozanzi.bsky.social @caixaresearch.bsky.social @danieljdrucker.bsky.social @cp-immunity.bsky.social @cyrilpedia.bsky.social www.jci.org/articles/vie...

Oh, the hype and spin!… I almost feel dizzy now… @adambecker.bsky.social @emilymbender.bsky.social podcasts.apple.com/pt/podcast/e...

The former NIH director on the catastrophe unfolding for American research. youtu.be/lW9c6t4potU