Every summer I repost this article on how to spot drowning. Please read it and pass on. In the last few years I’ve had SIX messages from people who saved a kid’s life after clicking on the link from my feed. slate.com/technology/2...

Finally got around to something I've been meaning to do for ages: run *exactly one* program on this computer. nick.zoic.org/art/boot-nak...

At this juncture I’d like to point out: * we’re on the brink of a golden age of medical healing * there’s enough money in the world to solve every problem in the world * a united approach could stop the climate crisis But a small group of sociopaths seeking personal power are going to throw it away.

Tbf most men would beat a gorilla in a boxing match, since the beast is unlikely to stick to the Queensbury rules and would be disqualified. The men would be dead, but they would win.

The human circulatory system, before and after proper cable management.

"Pancreatic cancer mRNA vaccine shows lasting results in an early trial: Scientists caution that more research is needed, but nearly all of the patients who responded to the personalized vaccine are still alive six years later."

I’m sorry WHAT

this bird is spiritually kin to our friend's parrot who, upon meeting us, immediately came over to our arm, bit us hard enough to draw blood, yelled FUCK YOU, then flew away laughing

Prenatal classes should include a visit to an old cemetery.

Chotiner: Perhaps you imagine yourself as the interviewee? Ricardo: I would never get tired of the, ummm, the ... Chotiner: ... Humiliation? Ricardo: Perhaps.

The 9th Annual Mutational Scanning Symposium starts tomorrow. We can't wait to see you for an action-packed 3 days of insightful presentations and posters and stimulating discussions. www.mss2026.org #VariantEffect26 #MAVE #Genomics #PrecisionMedicine #Symposium #AVEAlliance #AtlasOfVariantEffect

Drop a movie that traumatized you as a kid.

I think punk rock taught me this plus: (1) If you can’t do it, do it anyway (2) No one else will care about it as much as you do, so do as much of it yourself as you can (3) Support other people who are doing it the way you are and don’t cut people down

Happy Saint Patrick's Day! I wrote a review for a Mexican-Irish fusion restaurant in Jersey City, but also wrote about American identity in an empire in decline ☘️ johnpaulbrammer.substack.com/p/everyone-i...

This is "my Yankee Candle is defective, I can't smell it at all" but for cocaine

Neolithic hedgehog sculpture

Registration for MSS26 in Melbourne will close next Monday - we still have a few tickets available, and an amazing line-up of speakers across all areas of variant effects work, so if you were on the fence, check out our program and then smash that "Register now" button! www.mss2026.org

‪Doctors say that vaccines protect children from dangerous diseases. A nepo baby who barbecues dogs and snorts cocaine off toilet seats says that vaccines make children vulnerable to 5G radiation. For busy parents, it can be hard to know who to trust.

Wednesday's cartoon in The Mercury Newspaper: Jon Kudelka helped me get my first cartooning job at The Mercury. He also showed me how to be quick-witted and fearless. I was in a constant state of joke-envy over his cartoons. I'm gonna miss that feeling, but more than that, I'm gonna miss my friend.

I wrote about 'MELANIA' johnpaulbrammer.substack.com/p/my-melania...

#ShareGoodNewsToo "A vaccine called GBP511 has begun clinical testing in Australia. Pioneered by UW Medicine researchers, it is intended to protect against COVID-19 and related coronaviruses — including some that haven’t yet jumped to humans. www.ipd.uw.edu/2026/02/gbp5...

oh Antiques Roadshow what have you done now?

I heard a rumour that all the #StrangerThings issues will be resolved in a new special episode of #HalfLife 3.

it is your DUTY as a parent to be basic and cringe. if your child says "6-7" and you do not say, loud enough for their friends to hear, "8-9?", causing profound silence and intense discomfort, you are neglecting your responsibilities. being cool is for kids. your days of being laughed WITH are over

These two images of Chinese train driver Han Junjia were taken less than 30 years apart. Transformative change is possible when it is relentlessly pursued.

I think I've seen that guy somewhere before ...

Game designer: After lots of hard work we’re proud to announce we’ve created the Wheel of Saṃsāra from the ancient Buddhist classic Don’t Get Trapped in the Wheel of Saṃsāra

We are hiring for a web developer position, ideally with some experience in bioinformatics. This position is aimed at helping us turn our research in human genetics into useful tools. A background in either bioinformatics or web development is required. jobs.ethz.ch/job/view/JOP...

Clearly the way to avoid age restrictions is to use em dashs — you know, these things — or maybe just end all messages with old-school smileys :-/

I got a Mygov inbox notification today - a cursed thing that reignites the stress of #Robodebt and the stigma of welfare that the major parties keep alive by punishing the victims of capitalism with enforced poverty & early death. Yes it's a Robodebt class action notice.... #auspol

This is actually quite brilliant, up to and including the final sentence 🔥

“There were no cervical cancer cases diagnosed in women aged <25 years in 2021 – the first time that this has occurred in data going back to 1982. This remarkable achievement is almost certainly due to the impact of HPV vaccination.” From report.cervicalcancercontrol.org.au #vaccinationsaveslives

Why not come and visit Victoria, Australia where we have not just one Mount Buggery but two?

The room is almost all elephant. Almost none of it isn’t. Pretty much solid elephant. So there’s no room to talk about it. -Kay Ryan, “The Elephant in the Room” #everynightapoem

Thought I'd try this "vaping" thing the kids are all into.

In an old ad for board game Scattergories in Spain a player was shown flouncing out while anothet said “OK, we’ll accept ‘octopus’ as a pet”. “Aceptamos pulpo” has now entered the language in the meaning of “that’s a bit of a stretch but let’s go with it just for the sake of argument”.

just found out about elsa marie pade, an electronic music pioneer from denmark. this 1958 piece is WILD. imagine hearing this in 1958

📣Call for Abstracts for the Mutational Scanning Symposium! #VariantEffect26 🗓️ March 25-27, 2026 📍 Melbourne, Australia (and online!) 📝 Submit your abstract (deadline is Nov 2nd, 2025!) ➡️ Registration is also now open!! ℹ️ www.mss2026.org #FunctionalGenomics #Symposium #Australia #CallForAbstracts

I'm stoked to be organising next year's MSS right here in beautiful Melbourne! We know Australia is very far away, and we're working hard to make sure we can support as many ECRs to attend as possible, so please do register and apply for a travel award!

time dilation is real

Inspired by this + fossil giant Eni's fusion investments to update my 'greenwashing habitable zone' conceptualisation of what techs seem to lend themselves to being the most useful for bullshitty climate delay Welcome to the zone, fusion, you finally made the cut Top right = The Altman Expanse

Hilariously weird lease terms ... "Its to help not have any disagreements in the event of certain situations" is a great turn of phrase.

I collect pictures of gate latches. The endless minute variations and human ingenuity appeal to me greatly, and the countless hands that have moved them. This one is between Near and Far Sawrey, Lake District and has a lovely combination of textures between the iron, wooden gate, and stone gatepost.

A friend has a little one starting kindergarten. Their teacher: “They will learn to be good friends, to recognise and name their feelings, and to ask for what they need. Foremostly, they will experience joy and excitement while they do all of this learning. Oh and reading, writing & math.” 🥲

one morning, when gregor samsa woke from troubled dreams, he found himself transformed in his bed into a very hungry caterpillar

so many of the small indignities of daily life come from us being denied the ability to tell a rich man in a tech company to fuck off. minesweeper has microtransactions. paid services have ads. the opt out says maybe later. the drive thru is a broken chatbot. your car is an ipad. fuck off! fuck off!