1/ We are celebrating the Novo Nordisk Prize Symposium: Inborn Errors of Immunity – a huge success yesterday at the @institutimagine.bsky.social in Paris featuring talks by 19 leading European researchers on human IEI

Delighted to be speaking at the Novo Nordisk Symposium: Inborn Errors of Immunity, celebrating Jean-Laurent Casanova (my PhD advisor) and his landmark contributions. Join us Sept 24 at Institut Imagine, Paris. Free to attend! Details & registration 👇 #NNFPrize #Immunology

Exciting milestone for #HumanImmunity with the very first full issue of @jhumimmunity.org out now, including the #IUIS update on inborn errors of immunity + resources for clinicians. rupress.org/jhi/issue/1/1 #OpenAccess #IEI 👏👏👏

Delighted to share our manuscript highlighting the lessons learned from the clinical use of ex vivo T-lymphopoiesis assays to assist therapeutic decision-making btw #HCT and #thymus transplantation in patients without a molecular diagnosis after TREC-based newborn screening 👉 tinyurl.com/yzd8xe7p

1/ I was honored to accept the 2025 Novo Nordisk Prize from @novo-nordisk.bsky.social at today’s award ceremony in Copenhagen, Denmark. It was a wonderful day that included a tour of The BioInnovation Institute, lunch at @novo-nordisk.bsky.social, and an evening award celebration and dinner.

1/ Today we spotlight @sanchoshimizu.bsky.social, a postdoc in our Paris branch from 2006-12 and now Reader/Associate Professor at @imperialcollegeldn.bsky.social in the department of infectious diseases and head of both of a lab there and a satellite lab at the @crick.ac.uk

Open access, peer reviewed, and co-owned, @jhumimmunity.org from @rupress.org represents a new business model in scientific publishing. Rockefeller's Jean-Laurent Casanova is the founding editor-in-chief.

The #IBEX Knowledge-Base is an exciting initiative promoting open science and collaboration for immunofluorescence multiplexed imaging! New to this wonderful community and excited for the research ahead! Find out more 👇🏾

The @alexyema.bsky.social lab and colleagues show that dominant negative variants in ITPR3 impair T cell Ca²⁺ dynamics causing combined immunodeficiency. rupress.org/jem/article/... 📘 In Genes & Immunity collection: rupress.org/jem/collecti... #HKS2025

Very grateful to have been introduced to the wonderful #IBEX Knowledge-Base community 👇🏾 and to this novel spatial proteomics technique. Looking forward to more multiplexed imaging!

1/ I am both delighted and relieved to share my inaugural editorial for the @jhumimmunity.org rupress.org/jhi/article/...

Unjustified silence in the face of this new war in eastern DR Congo "Inaction implies resignation to the idea that the survival of the fittest governs the world's fate" Correspondence in @thelancet.bsky.social www.thelancet.com/journals/lan...

Our clinical experience using ex vivo T-lymphopoiesis assays to assist clinical decision-making between #HCT for #SCID & #thymus transplantation for #athymia in genetically undefined T-lymphocytopaenia is published 👉 doi.org/10.1016/j.cl... Thank you to all collaborators and referring clinicians!

Journal of Human Immunity (JHI) @jhumimmunity.org is here! Read the inaugural editorial by @casanovalab.bsky.social outlining #JHI’s vision as the destination for groundbreaking research in human immunity and inborn errors of immunity. https://buff.ly/4hRGpOb #OpenAccess

Our thymus, a critical source and trainer of T cells, involutes with aging. 2 new studies find a growth factor (FGF21) that delays involution (in mouse models) and may be a way to rejuvenate our immune system and promote healthy aging in the future.

Delighted & proud that this wonderful collection in @jem.org includes our study characterising dominant negative variants in ITPR3 in syndromic combined immunodeficiency patients due to calcium channel leakiness of the IP3 receptor, causing ER Ca2+ store depletion and impaired Ca2+ T cell dynamics.

Auschwitz was at the end of a long process. It did not start from gas chambers. This hatred was gradually developed by humans. From ideas, words, stereotypes & prejudice through legal exclusion, dehumanization & escalating violence... to systematic and industrial murder. Auschwitz took time.

Welcome to the future of #HumanImmunity research! @rupress.org and the International Alliance for Primary Immunodeficiency Societies (#IAPIDS) are launching the Journal of Human Immunity (JHI)! Stay tuned for groundbreaking, #OpenAccess research! 👉 https://buff.ly/4ajqm8W

What Happens When Some Cells Are More Dad Than Mom (and Vice Versa)? Latest from us. Published today. News here www.cuimc.columbia.edu/news/what-ha... article here: www.nature.com/articles/s41... @stewart_ojay @BogunovicLab and a huge international team thank you 🙏🏼

On behalf of @ESIDsociety clinical working party, we have written guidelines with clinical practice recommendations focused on the diagnosis, investigation, risk stratification, and management of congenital #athymia with the aim to improve patient outcomes. Out now in @jacionline: bit.ly/4g4qkUs

last 2 days to apply! : We have a fully funded #PhD #studentship available in my lab for Oct25 @UCLchildhealth. Project will research new treatments/targets for airway inflammation during viral infection using complex in vitro models. Deadline 13th Dec Apply here: forms.office.com/pages/respon...

We are thrilled to announce that Prof. Claudia Mauri will join Clinical & Experimental Immunology (CEI) as Editor-in-Chief from January 2025 🎊 Find out more and hear about Prof. Mauri's plans for the journal here👉 www.immunology.org/news/welcome...

Excited to share our 1st post ! Thrilled to share our latest research in Science Translational Medicine ! @science.org We show that RANKL administration reverses thymic involution and rejuvenates T cell immunity. @ciml.bsky.social #Aging #Thymus #Tcells #Immunology #Involution #Rejuvenation

Applications open for a new cohort of @dev-journal.bsky.social *Pathway to Independence* fellows Know a #devbio post-doc about to enter the academic job market? Would they benefit from a little support & mentoring? Spread the word Deadline 31 Jan 2025 journals.biologists.com/dev/pages/pi...

🚨Out now in Nature: Our spatial atlas of the developing thymus nature.com/articles/s41... Together with the labs of Sarah Teichmann, Ron Germain & John Marioni we present insights into the establishment of the thymic organ structure in pre- and postnatal life through a new spatial mapping approach.

Our latest preprint! - led by @makris1.bsky.social we find that Podoplanin expression in lymphoid tissue fibroblasts regulated their inflammatory signalling and crosstalk with immune cell populations doi.org/10.1101/2022...

We’ve jumped on board fully here on 🦋 A starter pack of those working on our favourite cell … the T cell 🥰🙈🥰 If you want an add let us know go.bsky.app/8B5P25c

First post on BlueSky. Whilst it is not related to DNA repair or replication, an interesting study I was peripherally involved in is out now in J Exp Med. Dominant mutations in ITPR3 give rise to combined immunodeficiency in humans. Big shout out to Alexandra Kreins. rupress.org/jem/article/...

I made a starter pack for those of us interested in or working on T cells. Let me know if you would like to be added or know somebody that should be added. Looking forward to scientific discussions and updates on our favorite immune cell type!