So nice to see our work out in print! Very special to have two of our eDyNAmiC papers in the same issue. What a beautiful cover! Thank you @elizsmckenna.bsky.social !! @aacrjournals.bsky.social

Thank you for inviting me to talk alongside Ido about our work on ecDNA!

Now online in Cancer Discovery @aacrjournals.bsky.social: Extrachromosomal DNA-Driven Oncogene Dosage Heterogeneity Promotes Rapid Adaptation to Therapy in MYCN-Amplified Cancers - by Giulia Montuori, Fengyu Tu, anton-henssen.bsky.social, Jan Dörr, and colleagues doi.org/10.1158/2159...

A huge thank you to all #IEAwards25 winners and nominees for an inspiring evening. We can’t wait to see what’s next on your horizon. Read more: bit.ly/44m94a0 #OnMyHorizon @anton-henssen.bsky.social, @nnennayakanu.bsky.social, @michellecruk.bsky.social @timwitney.bsky.social, @cuh.nhs.uk

I am excited, our collaborative work on tumours driven by ecDNA amplified MYCN and the underlying copy-number dependent fitness landscape just came out in Cancer Discovery @aacrjournals.bsky.social. @anton-henssen.bsky.social @cancergrand.bsky.social aacrjournals.org/cancerdiscov...

@anton-henssen.bsky.social we are looking forward to your presentation at #ecDNA25 in Mexico! Please share with your followers to let them know our early bird registration & talk submission close on 02 June 2025! 💰Grants available ✅More info: bit.ly/42XY0za

🚨🚨Paper out! 🚨🚨 Delighted to share our work, now published in ‪@natgenet.nature.com‬ 🧬! shorturl.at/94s5S We identified a targetable, chromothripsis-associated genetic event in blast phase (BP) MPN, a particularly poor prognostic subtype of acute leukaemia. 1/n Illustration: Hratch Arbach 🧵👇

Congrats Juliane and Monika authors.elsevier.com/sd/article/S...

New @theaacr.bsky.social Cancer Discovery paper on ecDNA in urothelial carcinoma reveals how ecDNAs: 💡 Drive #BladderCancer evolution 💡 Promote immune evasion 💡 Amplify oncogenes 💡 Fuel tumour heterogeneity 💡 May be a biomarker in urine for non-invasive detection aacrjournals.org/cancerdiscov...

Great conference ! I look forward to attending. 🔥🔥👇🏻👇🏻

Exciting new paper 🔥🔥👇🏻👇🏻

Great conference with expert lineup ! I look forward to attending! 🔥🔥👇🏻👇🏻

The Curtis Lab’s latest study on the genomic architecture of breast cancer from the pre-invasive to metastatic setting is now out in Nature! www.nature.com/articles/s41...

Here's our latest, led by Drs. Riaz Gillani & Ryan Collins - we studied a type of inherited genetic event (structural variants) + risk of developing certain cancers in kids: @danafarber.bsky.social @bostonchildrens.bsky.social @broadinstitute.org @science.org www.science.org/doi/10.1126/...

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Important work by Heribert Jürgens and colleagues on how telemedicine can improve the management of patients suffering from sarcoma. 👏🏻👏🏻👇🏻👇🏻 www.sciencedirect.com/science/arti...

Major milestone in ecDNA research!!! 👏🏻👏🏻👏🏻🔥🔥🔥👇🏻👇🏻

1/ In two back-to-back papers, we present our de novo TRACeR platform for targeting MHC-I and MHC-II antigens TRACeR for MHC-I: go.nature.com/4gcLzn5 TRACeR for MHC-II: go.nature.com/4gj5OQk

Thrilled to share a wonderful collaboration with Scott Armstrong, Florian Perner & Shellaina Gordon - exciting times ahead! www.biorxiv.org/content/10.1...

Great to see our joint study with @stesantaguida.bsky.social published in this month’s issue of Cancer Discovery: aacrjournals.org/cancerdiscov... With a super-kind Research Highlight written by Sam Bakhoum:

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Social media is in desperate need of innovation. Meta is only letting you have a slice of control over what you see because Bluesky is here building for you.

Amazing idea ! Hope it works. Would be very valuable method for early detection.

The international Curie « Noncoding Genome » course has been revamped! 👉 Dark genome in cell plasticity and heterogeneity. A session on TEs #TEsky with M.E. Torres Padilla, D.Trono and @aktast.bsky.social. Master, PhD and postdoc fellows, a week in Paris during the Spring? Apply before Feb 15th 📌

First Bluesky post - a BIG update to our study on Ewing sarcoma and other FET fusion-driven cancers. FET fusion oncoproteins are aberrantly recruited to DNA breaks and cause ATM defects, which can be targeted with the ATR inhibitor elimusertib. Updates include: www.biorxiv.org/content/10.1...

new out in Nature www.nature.com/articles/s41...

Right on time to discuss at #SNO2024: Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma. www.nature.com/articles/s41...

This week 11/22 at 4pm: Howard Chang, MD, PhD @stanfordmedicine.bsky.social presents "Cancer genes beyond chromosomes" at our Friday Seminar Series in Basic and Translational Research ow.ly/vbfJ50UaeaX

For my first post here at 🦋, let me tell you about a lovely paper by Richard Koche, @anton-henssen.bsky.social, and colleagues that covers how extrachromosomal DNA (ecDNA) drives cancer genome remodeling in neuroblastoma. It's a great story about cancer biology and genome organization! 🧬

First re-post on @bsky.app . Great collaboration between @kinglhung.bsky.social and team eDyNAmiC !! 🔥🔥👇🏻👇🏻

Hi everyone, I just joined @bsky.app and am happy to see so many fellow scientists here! I look forward to posting about cancer research / science and more.