Explore the origins, patterns and consequences of mutations across biological systems! #MITS26 🗓️ Conference dates: 13-15 April 2026 Participate in expert-led knowledge exchange on how genome evolution shapes human health and ageing 🧬 Check out our exciting speakers ➡️ bit.ly/4hmbnyr#MITS26#Genomics

My institution---the Sloan Kettering Institute, the basic science arm of the Memorial Sloan Kettering Cancer Center---is hiring new faculty this cycle! Applications close Nov 15. www.mskcc.org/research/ski...

Haha. L'État, c'est moi

Congratulations @mattjones.bsky.social @katerinakraft and the entire team

Looking forward, I am launching my lab in the @mitkochinstitute.bsky.social and IMES at @mit.edu, and will continue studying how the unique regulatory landscape of ecDNA enables tumor evolution. We're looking for creative scientists to push this frontier - if you're interested, get in touch!

man who tried to slash social security spending promises communism is coming if you just ignore the enormous job losses this year due to the technology he's developing for private profit

Famously, the UK has a history of cultural coherence www.theguardian.com/politics/202...

Yes, a citizen approach to brain surgery! Dont trust the experts, do your own research. Also, don’t use any electronics, this quantum mechanics hoax just tries to move you to the radical left. Can someone give him a lab practicum please. Maybe he understands then?

We are hiring a postdoc to profile the evolvability of tumors in longitudinal samples from three clinical trials as part of the ARPA-H ADAPT program. This is essentially an evolutionary bioinformatics position. If you are interested, please apply here ASAP apply.interfolio.com/172521

📢Exciting news! Cancer Discovery @aacrjournals.bsky.social is issuing another call for commentaries ahead of #AACR26! The meeting's theme is "Precision, Partnership, Purpose: Advancing Cancer Science to Save Lives Globally" - we want to hear YOUR ideas on how to achieve this goal. (1/2)

Professorship in plant genetics. The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See: www.berufungen.uni-kiel.de/de/dateien/o...

The continued move to open science and data and code availability is great. In cancer evolution, most publications now make data and code available, helping to speed up subsequent discoveries enourmesly.

If Trump gets the Peace Noble today, he should aim for Literature next. He clearly has all the best words.

Our latest work is out in Nature today. In this paper, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people www.nature.com/articles/s41...

The October issue of Cancer Discovery @aacrjournals.bsky.social is now online! The cover features two papers on the role of #ecDNA heterogeneity in tumor evolution and adaptation to therapy - you can find these papers and much more here: aacrjournals.org/cancerdiscov...

In the hope the academic system has and continues to improve since.

Very happy ecDNA has made the cover at @aacrjournals.bsky.social, highlighting two articles in the current issue, one on MYC(N) amplification in Neuroblastoma and one on the spatial heterogeneity of ecDNA amplified oncogenes in GBM. aacrjournals.org/cancerdiscov...

BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance" Stay tuned for more. #NobelPrize

Do you like theoretical biology, mathematical&conceptual modelling and want to apply yourself to cutting-edge research at all levels of biology, from molecules to ecosystems? Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Both in the near- and long-term: "Medicine and science will, if funded, find answers for autism, heart disease, cancer, birth defects, mental illness, and diabetes. Presidents, lawyers, and bureaucratic toadies will not."

Excited to announce that registration for the 13th @mathonco.bsky.social workshop on Treatment Revolution is now open. Held onsite @moffittnews.bsky.social Nov 2-Nov 7 #MoffittIMO more details: imo13.eventbrite.com. Deluxe travel awards are available on a competitive basis, apply by 10/03!

If you are interested in learning more about what an IMO Workshop is like check out our dedicated website: imoworkshop.org. Note the workshop this year runs directly after our #MathOnco25 meeting: mathematical-oncology.org/mathonco25.

But who reviews the reviewers?

Read Hannah Arendt. It’s all there, it’s all known and yet we fall for the same cheap demagogy time and again. What does this say about humankind?

Force always attracts man of low morality. A.E.

The IG noble in physics goes to Italy to discover the physics of pasta sauce. Amazing. I am sure that was a main scientific priority of the government supported by billions of euros 😂

“I think if it was possible, AI labs would have done it already.” … Well … www.nature.com/articles/d41...

And I am asking again. Where are the protests in the United States?

hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!

Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...

Published today in @aacrjournals.bsky.social Imran Noorani & @magnushaughey.bsky.social share the first evidence that ecDNA can build up in the healthy brain before tumours form in #glioblastoma — pointing to new early intervention strategies. 👉 www.cancergrandchallenges.org/news/ecdna-u...

I am very excited that Imrans and @magnushaughey.bsky.social article in @aacrjournals.bsky.social is now online. This was a great collaboration with @charlesswanton.bsky.social and Paul Mischel amongst many others. A small thread will follow below. aacrjournals.org/cancerdiscov...

We're back up and running after lunch - after David Rand's talk on the neural tube (which I forgot to get a photo for, sorry) we're now hearing about Weini Huang's work on ecDNA #UKMathBio

Yesterday the president demanded that evidence about Covid vaccines be shown to the public. Today @apoorvanyt.bsky.social & I run through some of the studies made public over the past 4+ years that show that the vaccines work. Gift link: nyti.ms/46k17Tq

My main PhD project is now up on bioRxiv! If you’re interested in somatic evolution or machine learning for simulation-based inference, read on…
 doi.org/10.1101/2025... [1/15]

Our new review is out in Trends in Cancer. We had fund writing this :) We discuss the roles of retrotransposons in immune modulation in normal and malignant hematopoiesis. www.cell.com/trends/cance...

Looking for a new team member to join us on our journey of discovery. #mathonco #evolution #antibioticresistance @cbo.bsky.social @sandyanderson.bsky.social @mathonco.bsky.social @natphys.nature.com @aaas.org

#MathOnco25 Abstract submission is being extended until this Friday the 5th of September! So please go ahead and submit asap to have a chance of getting one of our travel awards! mathematical-oncology.org/mathonco25

“For a successful technology, reality must take precedence over public relations, for Nature cannot be fooled.” This has to be shouted from every roof, every street and towards any science deniers in government or the media.

Ruler in my daughters primary school. To make sure you never learn conversion of cm and inches 😂

I truly dislike the habit in the UK to use abbreviations all the time. I always die a little when I see C of E in a newspaper

I wrote an op-ed on the world-class STEM research ecosystem in the United States, and how this ecosystem is now under attack on multiple fronts by the current administration: newsletter.ofthebrave.org/p/im-an-awar...

Now online in Cancer Discovery @aacrjournals.bsky.social: Extrachromosomal DNA-Driven Oncogene Dosage Heterogeneity Promotes Rapid Adaptation to Therapy in MYCN-Amplified Cancers - by Giulia Montuori, Fengyu Tu, anton-henssen.bsky.social, Jan Dörr, and colleagues doi.org/10.1158/2159...

The only place in DC where crime is up is the White House.

BBC International Editor Jeremy Bowen has confirmed that the entire Al Jazeera team in Gaza City has been killed.

Same day in the UK www.theguardian.com/uk-news/2025...

Planwirtschaft www.nature.com/articles/d41...

In this #Essay, @cmaley.bsky.social @jeffreytownsend.bsky.social @lucielaplane.bsky.social @plutynski.bsky.social &co examine how evolutionary selection operates across levels, highlighting how this understanding can be used to improve #cancer prevention and treatment 🧪 plos.io/47epeUq

I am excited, our collaborative work on tumours driven by ecDNA amplified MYCN and the underlying copy-number dependent fitness landscape just came out in Cancer Discovery @aacrjournals.bsky.social. @anton-henssen.bsky.social @cancergrand.bsky.social aacrjournals.org/cancerdiscov...