Last weeks @mathonco.bsky.social research in progress is by Agata Xella from the #AndersonLab presenting, Modeling CDC7i and PKMYT1i Synergy in Ovarian Cancer @moffittnews.bsky.social

Fab closing presentation by friend and #mathonco agitator @gliomath.bsky.social from @cedarssinaicancer.bsky.social presenting cool new work, Every Patient Deserves Their Own Equation: Towards Digital Twins for Neuro-Oncology.

The penultimate talk is from friend and collaborator Mark Chaplain from St. Andrews University presenting, A Mathematical Modelling Framework for a Virtual Solid Tumour: Foundation for an Oncological Digital Twin.

Next up is Katie Bentley from @crick.ac.uk on Simulating pathological vascular dynamics.

Opening the afternoon session is Hector Gomez from Purdue University presents, Prostate: Small Organ, Big Problems—informing clinical decisions with computational models.

Excited to announce that registration for the 13th @mathonco.bsky.social workshop on Treatment Revolution is now open. Held onsite @moffittnews.bsky.social Nov 2-Nov 7 #MoffittIMO more details: imo13.eventbrite.com. Deluxe travel awards are available on a competitive basis, apply by 10/03!

Closing the morning session is Olivier Gevaert from @stanforduniversity.bsky.social presenting, Multimodal data fusion for precision medicine and digital twins.

Next is friend and fellow Department chair @gibin.bsky.social from @swanseauni.bsky.social presenting, A Multiscale Modelling Framework for Studying Cancer Growth and Treatment Responses.

Next is Simon Walker-Samuel @ucl.ac.uk presenting, Digital twins of the retina as a model for cancer.

Interested in doing a PhD in #MatOnco next year? Our department at @moffittnews.bsky.social is a great place to do research and we offer fully-paid tuition and fees. Apply before the deadline 12/1 at Moffitt.org/CancerPhD

Then our very own Jill Gallaher discusses our ongoing @evoltherapy.bsky.social clinical trial with @genentech.bsky.social on, Adaptive therapy in advanced basal cell carcinoma driven by imaging and predictive mathematical. #AndersonLab @mathonco.bsky.social @moffittnews.bsky.social

Next up was short presentations by Luciana Luque from @cruk-si.bsky.social discussing, From measurement to decision: a tissue-aware digital-twin platform for CAR T cell dosimetry.

Opening day 2 of Mathematical Foundations of Oncological Digital Twins at The NewtonI nstitute is Trachette Jackson from @umich.edu presenting, From PD-L1 to PSA: Virtual Clones and Cohorts in Action Across Cancer Types and Therapeutic Modalities.

Final presentation for today by Richard Gilbertson from Cambridge University and CRUK Cambridge Institute presenting, Context Drift and the Virtual Mouse: new approaches to better cancer treatments.

Next Justicia Kyeremeh from Cambridge University presenting, From Data to Decisions: Building the Digital Twin Framework for Personalised Kidney Cancer Surgery.

Opening the final session for today is Anna Sher from GSK presenting, Oncological Digital Twins in Drug Discovery and Development: A Quantitative Systems Pharmacology Perspective. Sadly most of the slides couldn’t be shared. But Anna’s message was industry is ready to share!

Opening the afternoon session is Jasmine Fisher from @ucl.ac.uk presenting, Precision Oncology through Digital Twins: Mechanisms, Models, and Clinical Applications.

Next up is friend and community player extraordinaire @mathcancer.bsky.social from Indiana University presenting, Advances in building patient-specific agent-based models in cancer.

Next up is friend and collaborator @trevorgraham.bsky.social from @icr.ac.uk presenting, Modelling drug resistance evolution. Most of his talk is unpublished so I didn’t photograph it!

Next up is @eriksahailab.bsky.social from the @crick.ac.uk presenting, Using inference and modelling to understand how cancers change over time.

It was great to see friend and former @mathonco.bsky.social member @stroblmar.bsky.social presenting a vision for his independent research here in the UK! He’s gonna be one to watch for sure.

Attending ‘Mathematical Foundations of Oncological Digital Twins’ meeting at the Newton Institute in Cambridge organised by Steven Niederer and Helen Byrne. Watch along with me here: www.newton.ac.uk/event/ooew07/

Good friend @sandyanderson.bsky.social is giving the 1st keynote address on virtual cancer trials, virtual tumor boards, and using patient-calibrated models to plan individual treatments to delay therapeutic resistance. Groundbreaking work making a difference in real patient trails! #mathonco

Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...

Today’s @mathonco.bsky.social research in progress is from Jeffrey West lab member Ari Barnett presenting, Moment-Informed Radiotherapy: Inferring inter-patient radiosensitivity with probability convolution @moffittnews.bsky.social

For last weeks @mathonco.bsky.social research in progress we had the new chair of Translational Pathology, Ignacio Wistuba sharing his vision for the new department that will explicitly integrate computational approaches @moffittnews.bsky.social

I’ve not been on top of my research in progress presentations for @mathonco.bsky.social So here are some catch ups! 2 weeks ago we have Tao Li from @einsteincross.bsky.social lab on, Characterizing how selection pressures shape Karyotype Fitness Landscapes (KFLs) @moffittnews.bsky.social

#MathOnco25 Abstract submission is being extended until this Friday the 5th of September! So please go ahead and submit asap to have a chance of getting one of our travel awards! mathematical-oncology.org/mathonco25

This paper took the scenic route to publication: paused for maternity leave, rerouted by other work priorities, and finally dusted off like a forgotten treasure in the attic when my brilliant student Amy came on board.

Really excited to share our new @cellpress.bsky.social Cell paper with @fertiglab.bsky.social and colleagues. 1/n www.cell.com/cell/fulltex... @jktgfoundation.bsky.social @itcrtraining.bsky.social @smbmathbiology.bsky.social #mathbio #mathonco @mathonco.bsky.social @deniswirtz.bsky.social

Out now @dev-journal.bsky.social Transition paths across the epithelial-mesenchymal transition landscape are dictated by network logic Through investigation into the role of logic in GRN models, we discovered that choice of logic (AND vs OR) profoundly impacts cell fate. doi.org/10.1242/dev....

Closing this session is another one of our @mathonco.bsky.social faculty, @cancerevo.org David Basanta: "Calibrating a Spatial Agent-Based Model of Multiple Myeloma Using In Vivo Data to Predict Immunotherapy Response" #SMB2025 @moffittnews.bsky.social

Next up is our very own @mathonco.bsky.social faculty @rejniaklab.bsky.social presenting, "Using tumor histology to analyze cancer immunotherapies with the agent-based micropharamacology model" #SMB2025 @moffittnews.bsky.social

Now attending a minisymposium on parameterising agent based models organized @dwodarz.bsky.social lab, 1st up is @utaustin.bsky.social member David Hormuth on "Leveraging longitudinal experimental data to parameterize mathematical models of tumor growth and response” #SMB2025

Former HAL developer and @mathonco.bsky.social student, Rafael Bravo now with @utaustin.bsky.social presents new work on: "Testing the feasibility of estimating the migration to proliferation rate ratio in glioblastoma from single time-point MRI data" #SMB2025

Today’s morning plenary and John Jungck Prize lecture is from @smbmathbiology.bsky.social former president, Fred Adler (@dendroicap.bsky.social) on "Education, Bureaucracy and Corruption". He manages to discuss some of his virus work with former @mathonco.bsky.social member Anna Miller! #SMB2025

Yesterday's #mathonco minisymp with @mathonco.bsky.social @moffittnews.bsky.social's chair and friend @sandyanderson.bsky.social presenting models that capture patient data and help us to understand how to improve treatment schedules in a clinically translatable way

"Patients should be their own control" - great & pithy takeaway from @sandyanderson.bsky.social in his talk on the adoption of adaptive therapies in the clinic #SMB2025 #MathOnco

Next up is friend and collaborator @rrockne.bsky.social from @cityofhope.bsky.social presenting "State-transitions at the single cell and system levels in chronic and acute myeloid leukemia" #MathOnco #SMB2025

Next up is Sara Hamis @uppsalauniversity.bsky.social in a parallel #MathOnco session on "Growth rate-driven modelling elucidates phenotypic adaptation in BRAFV600E-mutant melanoma" #MathOnco #SMB2025

Next up is former student & friend @stroblmar.bsky.social presenting new work with @cancerconnector.bsky.social on “Bridging the gap: What preclinical experiments can teach us about cancer drug scheduling” #MathOnco #SMB2025

Opening 1 of 3 parallel #mathonco sessions this AM is Thomas Yankeelov from @utaustin.bsky.social shows "A practical computational framework for systematically investigating alternative treatment strategies for cancer”. Tom show realworld results from a digital twins driven clinical trial! #SMB2025

A packed opening plenary from one of the @smbmathbiology.bsky.social Canadian giants! Mark Lewis “One equation helps solve three paradoxes in the spatial ecology of predators and prey” Mark also wins the prestigious Akira Okubo Prize!! #SMB2025

Over a month ago a bunch of #MathOnco and #AIOnco researchers got together in Syracuse to discuss how #AI may and may not change the field. Here are some thoughts in a collective effort led by @rrockne.bsky.social:

A week away from the start of the @smbmathbiology.bsky.social meeting in #Edmonton so it seems like an apt time to share my convo with conference organizer, Jay Newby. You'll also hear me nerding out about potassium channels in neurons 🧠 smb.org/news/13516785 #SciencePodcast #BiologyInNumbers

A behind-the-paper post by Einar Gunnarsson: Optimal #dosing of anti-cancer drug treatment under drug-induced #plasticity

Big shout out to rising M4 and CWRU MSTP student Eshan King - whose paper came out in @aaas.org Science Advances. connecting the fields of PK-PD and evolutionary modeling using fitness seascapes. #mathevo #mathonco @cbo.bsky.social @sandyanderson.bsky.social www.science.org/doi/10.1126/...

Fantastic upcoming 2-day workshop on digital twins for cancer care at Oxford's Isaac Newton Institute, September 18-19 this year. This workshop will have a fantastic set of experts, and I'll also give a keynote talk on our cancer immunology work. 🧪 1/8 Apply at: www.newton.ac.uk/event/ooew07/

WOW!.. 8500+ supporting cast heroes (that's us!) have already signed our Letter of Support for the brave NIH heroes who laid down their case in the historic #BethesdaDeclaration. Add your name here actionnetwork.org/forms/add-na... & stand up to save science & health in America. #StandUpForScience

Attending a conference entitled, The Future of Cancer Research: Unleashing the Power of Machine Learning, taking place in the historic city of Syracuse. Organized by @cityofhope.bsky.social @sergiobranciamore.bsky.social, Andrei Rodin, Konstancja Urbaniak and @rrockne.bsky.social