Do extra chromosome sets mask bad mutations? Simulations show tetraploids often carry higher genetic load than diploids, depending on dominance, demography, and drift—with important implications for fitness and conservation. academic.oup.com/evlett/artic...

🧬 Just out in Bioinformatics Advances: “tskit arg visualizer: Interactive plotting of ancestral recombination graphs.”  Read the full paper here: https://doi.org/10.1093/bioadv/vbaf302 Authors include: @kitchensjn.bsky.social, @yanwong.bsky.social

Now out! How important is social experience in male mating behavior? @corrallopeza.bsky.social found that experienced males were more likely to coerce non-receptive females, but did not change overall preference onlinelibrary.wiley.com/doi/10.1002/... w/ @vdbijl.bsky.social @idarolti.bsky.social

I am currently searching for a new postdoctoral researcher to study the evolution, genetics, and physiology of cold acclimation and freezing tolerance in switchgrass at Michigan State University. This work will be funded by a newly funded five-year DOE grant. careers.msu.edu/jobs/researc...

We have TWO post-doctoral fellowships in the Biodiversity Centre at UBC next year! Am happy to chat if you might want to be hosted in my lab. biodiversity.ubc.ca/training-and... Deadline January 15th!

Elevated mutation near crossovers inhibits the evolution of recombination https://www.biorxiv.org/content/10.1101/2025.11.01.685904v1

Great to see that our mosquito cell atlas is now out in Cell. Amazing work from @oliviagoldman.net and @nadavshai.bsky.social to organise so much data and so many interesting stories into a single paper!

The Johri Lab has an open postdoc position. Please send me an email, if interested. Start date is flexible. Please do share! Thank you in advance.

The Hopkins Lab (hopkins-lab.com) at the University of Florida is looking to recruit a postdoc to work on the genetics of organ function and evolution across Drosophila and beyond. Please visit tinyurl.com/vcsjpmzz or email me for more info. And please RT or send to anyone who might be interested!

Hey Yaniv Brandvain is not on Bluesky but his most recent biostats ebook is live ybrandvain.github.io/biostats/. His stats resources have been so helpful to me as I develop my own stats course, so check it out. Github repo here: github.com/ybrandvain/b...

Separating selection from mutation in antibody language models https://www.biorxiv.org/content/10.1101/2025.10.21.683652v1

The Genomic Architecture of Local Adaptation in Two Connected Populations of Three-Spined Stickleback. https://www.biorxiv.org/content/10.1101/2025.10.21.683682v1

One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential. www.biorxiv.org/content/10.1...

In a new paper led by Jiaqi Yang we trace the distribution of Denisovan introgressed DNA in ancient modern human genomes over time. www.cell.com/current-biol...

We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT

#PhD Position: Interested in the evolutionary and ecological impacts of whole genome duplication? Join Dr. Tia-Lynn Ashman @drtialynn.bsky.social and I at the U. of Pittsburgh, to test what drives the competitive outcomes between diploids and #polyploids Details: shorturl.at/nQ8UW

Sharing our new paper, "Distinct haplotypes and reversed dominance at a single-gene balanced polymorphism controlling heterodichogamy in two genera of wingnuts". Genomics & evolution of a mating type system involving two morphs with alternating sexes in walnut relatives www.cell.com/current-biol...

Now available in Systematic Biology, a new paper (and R package) in which we outline an approach to account for non-independence in comparative analyses of lineage-pair traits academic.oup.com/sysbio/advan...

I am hiring a postdoc to examine the genomic and evolutionary basis of plant microbiome variation in legumes. There are opportunities to gain teaching experience. Chicago is a great city to live in! Please help spread the word. share.google/gukbzS1zdIx6...

For “Reflections on the history of modeling and theory”, @sarperotto.bsky.social and I met with Joel Cohen. We learn how he navigated math and biology, the value of embracing ignorance, and what is a population. Or really, what _isn't_ a population: www.youtube.com/watch?v=RCt9... @smtpb.bsky.social

New preprint led by grad student, Yu Mo! We introduce new software to calculate evolutionary rates of quantitative characters in the presence of discordance 1/ www.biorxiv.org/content/10.1...

New paper by former MSc student @christeinecke.bsky.social! ⭐ A behemoth effort to apply artificial selection on clonal reproduction in #Mimulus guttatus. We show that clonality evolves quickly, but not symmetrically in both directions, and multivariate life history traits are altered too! 🧪🌾

Human-mediated land-use and climate change occur simultaneously, but how do they interact to shape adaptive dynamics? Super excited to share the first paper from the Kreiner lab, led by postdoc extraordinaire @rpineau.bsky.social

Any academic folks on H1B visas (even with stamps in passports) please get legal advice from your University attorneys before leaving the US.

I'm looking for PhD students to join the lab starting August 2026. We study the evolution of insect chemical signals so if you're interested in evolutionary biology, chemical ecology, molecular biology, behavior, or genetics, this could be a good fit for you! More info here: tinyurl.com/mrxchwfm

How many chromosomes can an animal have? In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact. www.cell.com/current-biol...

Out today in @genetics-gsa.bsky.social #G3journal - our manuscript describing biases in summary statistics like genetic differentiation (Fst), diversity (pi), Tajima’s D, and estimates of theta, migration rates, and divergence times when not accounting for ghost gene flow. doi.org/10.1093/g3jo...

Introgression and Parental Conflict Underlie Repeated Occurrences of Postzygotic Isolation https://www.biorxiv.org/content/10.1101/2025.08.12.669975v1

Unique genetic bases of repeated life-history divergence associated with high altitude adaptation in Mimulus perennials https://www.biorxiv.org/content/10.1101/2025.08.12.669946v1

FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...

Thanks so much to @trstngnthr.bsky.social for seeing this through. This paper started like 7 or 8 years ago when I was still at Temple!

My company is hiring a computational biologist! This role is the same position as mine, and will involve building genomic prediction models, some bioinformatics, and a lot of independent research on developing new methods to improve our crop development initiatives. www.linkedin.com/jobs/view/42...

"The molecular evolutionary basis of species formation revisited" by Molly Schumer (@mollyschumer.bsky.social) & colleagues "The origin of species has long fascinated biologists, but determining the genes [involved] has only recently become possible in non-model organisms." shorturl.at/wG0B5

Incredibly proud of this work where we developed a method for understanding the information contained in millions of genomes. Another example of NIH funded research.

New work from Josephs lab grad student Asia Hightower @puffballove.bsky.social w/ Dan Chitwood & many many others on general, flexible methods for analyzing leaf shape variation www.biorxiv.org/content/10.1...

Excited to finally have the pre-print up for this work on evolutionary rescue from my PhD at UBC! Previous theoretical work on the effects of negative density-dependent growth on evolutionary rescue has uncovered inconsistent results, leading to an incomplete understanding of its influence.

This began as a @jgi.doe.gov Community Science Program (CSP) project in 2017 with the goal of uniting the diverse sorghum breeding and mapping populations in the framework of a 'pangenome'. Thanks to a huge efforts across many stakeholders, the article was preprinted today. A 🧵 w/ what we found:

🚨🚨 New tenure track position in #ConservationBiology @oberlincollege.bsky.social in the #Biology department--come join us, and contribute to our brand new Environmental Science major too! #biologyjobs #ecologyjobs jobs.oberlin.edu/postings/16671

"We found that TF orthologues from distant species retain nearly identical binding preferences, while on the same timescales the gain and loss of TFBSs are widespread." From: www.nature.com/articles/s41...

When I was little, the U.S. military came to our home at gunpoint and took me and my family away. We were imprisoned for years in barbed wire camps simply because we were Japanese American. I have spent my life telling that story, hoping it would never be repeated.

My talk from this year's probgen is finally out. Where do linear mixed models and random effects come from? They emerge from *mutations* on Ancestral Recombination Graphs.

hadn't seen this

A network perspective on the evolution of hybrid incompatibilities https://www.biorxiv.org/content/10.1101/2025.07.09.663985v1

Please share! Our lab is recruiting a PhD student to join us starting fall 2026. Our group is broadly interested in plant molecular evolution and comparative genomics. More info about our lab and grad programs at Colorado St. is available on our lab website. sites.google.com/site/danielb...

Staff scientist position (computational): I am looking for a computational scientist to join my genomics lab at Stanford. They should have an outstanding skillset in ML/statistical methods for genomic applications, postdoc experience and a strong publication record. #sciencejobs

Excellent work out from postdoc Remi Ketchum in @samurscicop.bsky.social's lab 👊🔥🦟

Out now in @molbioevol.bsky.social with Michelle Liu (co-first), Ryan Frost, Matthew Lindsay, Malak Bayoumi, Martin Brengdahl, @ruxmolnar.bsky.social and @aneil-agrawal.bsky.social, we evolved ~40% of the D. melanogaster genome under male-limited inheritance, ... academic.oup.com/mbe/article/...