APOL1 high-risk variants predispose to CKD in people of African genetic ancestry due to podocyte toxicity; CAKUT have variable outcomes potentially driven by podocyte injury. Read this Original Article on APOL1 kidney risk variants & outcomes in children w/CAKUT. link.springer.com/article/10.1...

New systematic review and meta-analysis in #ASNCJASN: The Association between Low-Grade Proteinuria and Adverse Kidney Outcomes in IgA Nephropathy. Check it out: kidney.pub/CJASN0952

B Cell Depletion in Glomerular Diseases: Not Always as Safe as We May Think - Kidney Medicine www.kidneymedicinejournal.org/article/S259...

From a chance encounter years ago, far away, to this milestone today. Proud to have been involved in this research! Breakthroughs happen when we share ideas and challenge paradigms. Science moves forward when we work together—and this is just the beginning. #Nephrology #Research #TeamScience

In 2020, we started to question whether #idiopathicnephroticsyndrome is strictly a 'pure' podocytopathy. Today, I am happy to share our new manuscript proposing a role of the glomerular endothelium in the disease pathogenesis. urldefense.com/v3/__https:/...

Excited for this new opportunity! The UMN Department of Pediatrics has been my home for a long time and I’m honored to lead us through this transition.

excellent review of complement based therapies in ...IgA Nephropathy in @ajkd.bsky.social from @sstoneman.bsky.social et al www.ajkd.org/article/S027... Fig 1 with the 4-hit theory 1/

Around three weeks left to register for the 15th Annual Glomerular Disease 2026 Conference on Friday, February 6th, 2026. Feel free to register for our virtual conference using the following link: www.eventleaf.com/At...

Join us! NAVBO's virtual workshop🚀 Specification of EC Phenotypes Feb. 10-12 (12-4:30 PM ET). Learn more about EC's adaptability!! Can't join us? Recordings will be available to all registrants for one month after the meeting! See the full program and register here: www.navbo.org/feb2026/

Registration NOW Open for 'The 49th Annual Columbia Renal Biopsy Course’ - July 15-17, 2026 - an in-person & virtual program with ACCME credits & video access. Click for agenda, full details & registration: www.eventleaf.com/e/RenalBiops...

SMOC1, a matricellular protein, antagonizes EndMT in vitro IL-1β + TGFβ2 🐭Aortic arch greater vs lesser curvature 🐭Myocardial infarction How? SMOC1 binds to Endoglin ⏫Long-to-short Endoglin isoform ⏫BMP-SMAD1/5 ⏬TGFβ-SMAD2 Ingrid Fleming lab bioRxiv 2025 www.biorxiv.org/content/10.6...

By 2050, chronic kidney disease (CKD) is projected to become the fifth leading underlying cause of death worldwide. A new Seminar provides a simple approach to CKD diagnosis, staging, and management that can be applied in most clinical settings: spkl.io/63323AlsFF

The Italian Society of Nephrology expresses its deep sorrow for the passing of Prof. Claudio Ponticelli, a pioneer in nephrology and an outstanding scientist and mentor. Our heartfelt condolences to his family and colleagues. #RIP #Nephrology

Sodium-glucose co-transporter 2 inhibition improves age-dependent kidney microvascular rarefaction doi.org/10.1016/j.kint.2025.12.011 #OpenAccess #MedSky #NephSky #AfricanTurquoisekillifish #SGLT2i

Great collaboration with the @kidneyomicsamps.bsky.social lab! Thank you Matt for bringing back #MEFV for me, the disease that ignited my interest for #humangenetics when I was still a student! And now a risk factor for #FSGS! When things come together.. www.kidney-international.org/article/S008...

Mini Review by Kristen L. Nowak and Michel Chonchol: Targeting Inflammation in CKD bit.ly/46TMzsY (FREE)

The Science Direct site for KICR seems broken Until then: Journal website: www.kicasereports.org Editorial Manager: www.editorialmanager.com/kicr/default...

Nephrotic syndrome genomic discovery in the Mass General Brigham Biobank identifies monoallelic MEFV variants as a risk factor for focal segmental glomerulosclerosis #nephsky #nephrology www.kidney-international.org/article/S008...

New out today: Antiproteinuric Effect of Sparsentan in Patients with Genetic-Associated FSGS Enrolled in the DUPLEX Trial Genetic FSGS CAN be treated. journals.lww.com/cjasn/abstra...

eQTL analysis helps us pinpoint where genetic variants influence gene activity, giving us insight into the regulatory signals behind complex diseases. Learn more in our paper published in 2023 buff.ly/kfJKVmH

Happy Tuesday! Take a look at "Trial of Pegcetacoplan in C3 Glomerulopathy and Immune-Complex MPGN" with Dr. Bomback as a coauthor www.nejm.org/doi/10....

Commentary Berger disease redux Richard J Glassock doi.org/10.1016/j.kint.2025.09.021 Original article: doi.org/10.1016/j.kint.2025.07.038 #MedSky #NephSky

Registration remains open for the 15th Annual Glomerular Disease 2026 Conference on Friday, February 6th, 2026. Feel free to register for our virtual conference using the following link: www.eventleaf.com/At...

This weekend was @kidneyomicsamps.bsky.social Birthday! We celebrate a leader whose passion for pediatric nephrology, genetics, and innovation inspires our team every single day. From advancing “kidneyomics” research to improving care, Dr. Sampson leads with purpose and heart!

Registration remains open for ANCA-Vasculitis 2026: Diagnosis, Treatment & Comprehensive Care of Patients, taking place on Friday, March 6, 2026. Register today using the following link: www.eventleaf.com/AN...

Disease modification in IgA nephropathy doi.org/10.1093/ndt/...

More great news from Dr. Katherine Tuttle, who is quoted in the article: "Mechanistic effects of semaglutide reduce albuminuria, preserve glomerular filtration." @uwmedicine.bsky.social @uwnephrology.bsky.social #nephsky #kidney #glomerular #CKD #semaglutide #diabetes www.healio.com/news/nephrol...

Looking forward to the ASSENT ( #Alport syndrome surrogate endpoints network) meeting today with the FDA. We need new effective therapies and paving a regulatory path is the first step.

Described in #ASNCJASN, researchers developed a custom-made Joslin OLINK proteomics platform was developed to quantify 21 Joslin kidney panel (JKP) proteins in circulation to predict ESKD risk. Read more: kidney.pub/CJASN0863

Registration remains open for the 15th Annual Glomerular Disease 2026 Conference on Friday, February 6th, 2026. Feel free to register for our virtual conference using the following link: www.eventleaf.com/At...

From RAAS blockade to regenerative medicine: evolving treatment strategies in #Alport syndrome pubmed.ncbi.nlm.nih.gov/41243004/

Another simultaneous publication from the afternoon session Albuminuria as an acceptable surrogate outcome (per our discussion earlier today) www.nature.com/articles/s41... in @naturemedicine.bsky.social @nature.com sadly paywalled #KidneyWk

📢 New Glomerular Diseases Guideline out now! 🧒 Up-to-date recommendations on diagnosing & treating immune-mediated #GlomerularDisease in children. 💊 Guidance on immunosuppression & supportive care. ✅ Endorsed by @BAPNnephrology 📃: ow.ly/HtZL50XnTCL#GlomerularDisease #KidneyDisease

Previously shared: Systemic shock can lead to vascular dysfunction and organ failure. This issue’s cover features work by Alejandro P. Adam @aleadam.bsky.social showing inflammatory cytokines drives endothelial stress via cytoplasmic DNA. www.jci.org/articles/vie...

This is not an acceptable status quo. Children with kidney disease are being left behind. #KidneyWk

Pediatric nephrology is currently facing a shortage of physicians and unfilled fellowship positions. In this month's #ASNKidneyNews, one resident shares their perspective. kidney.pub/KN1710-05#ASNKidneyNews,

Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com

APRIL is key 🔑 in the development of Antibody-secreting B lymphocytes ca. 2018 from @JASN_News #IgAN #Nephpearls #RKDSummit #NephSky 👉 pubmed.ncbi.nlm.nih.gov/29326157/

Dr. Liz Kiernan talks us through "Endothelium in Kidney Health and Disease," by reviewing #kidney vasculature #physiology and eGFR, structure and function of #endothelium, #pathophysiology and signaling, #biomarkers and #therapeutics. @uwmedicine.bsky.social #nephsky Watch: youtu.be/b1Nr0QRcVeQ

Progression of Coronary Artery Calcification and Risk of Clinical Events in CKD: The Chronic Renal Insufficiency Cohort Study bit.ly/48yjx4v #OpenAccess

And it’s live Iptacopan in C3GN makes it to @thelancet.com www.thelancet.com/journals/lan... #NephSky

Today is #C3GAwarenessDay! At ISGD, we stand with people living with this rare kidney disease. As a medical society for #GlomerularDisease experts, we're committed to raising awareness and moving the science forward to bring more hope and solutions to the C3G community. #C3G #ISGD

Clinical Endpoints for Glomerular Diseases from @hjanders.bsky.social #GlomConHawaii 🌊 #Nephpearls #NephSky

➡️ Randomized, Double-Blind, Placebo-Controlled Phase 2a Study Assessing the Efficacy and Safety of Felzartamab for IgA Nephropathy www.kidney-internati...

The @kdigo.org IgA guidelines published www.kidney-international.org/article/S008... We discussed them with Jon Barratt here: youtu.be/OChs5BcTEGE?... on #NephGR