A sweet result in sepsis doi.org/10.1172/JCI2... Eric P. Schmidt @schmidtlab.bsky.social & team find plasma concentrations chondroitin sulfate predicted the response to a randomized liberal or restrictive intravenous fluid resuscitation strategy in patients with sepsis and hypotension

The ISN Genetics Curriculum is now live, helping nephrologists apply genetic testing for earlier diagnosis and personalized care. It includes 11 expert-led lectures and global roundtables on PKD, Alport syndrome, complement disorders, and more Explore it: https://bit.ly/4smpBmM

Around 12 people die every day waiting for a kidney transplant. But hope is on the horizon. Scientists are testing pig kidney transplants in humans, also known as xenotransplantation. We spoke with two experts to answer your most pressing questions. www.kidney.org/news-stories...

🎉 Congratulations to Sidhant Puntambekar, Michelle McNulty, and Janewit Wongboonsin for co-authoring this new paper in JAMA Network Open! Proud to see members of the Sampson Lab contributing to this important research. 👏 #KidneyResearch #Genomics #Nephrology

A little something I wrote about the patient perspective of disease: www.sciencedirect.com/science/auth... #IgANephropathy #IgAN #NephSky #MedSky

The patient voice belongs at ASN Kidney Week. Cele’s Champions provides travel support to attend #KidneyWk, plus ASN membership. Bring your perspective forward as an individual living with kidney disease or care partner representing 850 million people worldwide 🔗 http://asn.kdny.info/AnIy50YyPTi

If you or a loved one has nephrotic syndrome diagnosed in childhood this is for you. BIGKiDs brings together patients and families across all ages to help uncover the genetic causes of kidney disease. Your story matters, and your experience helps.

Proteinuria has long been the key marker of glomerular disease activity—and reducing it is a central treatment goal. But not all proteinuria reflects the same underlying process #ASNJASN #Perspective kidney.pub/JASN1093

Is It Time to Review How We Use Proteinuria to Define Disease Activity in Glomerular Diseases? journals.lww.com/jasn/citatio...

Comparative Effectiveness of Antihypertensive Medications in Children With Chronic Kidney Disease jamanetwork.com/journals/jam...

C3G has entered its championship era!! It is no longer just “interesting biology” but one of the most exciting treatment stories in nephrology. Loved writing this commentary on why complement-targeted therapies could be a real game changer for patients. @nephmadness.bsky.social

Nobel prize–winning Treg cells in autoimmune kidney diseases and transplantation #nephsky #nephrology www.kidney-international.org/article/S008...

Clinical course of proteinuria due to cubilin variants: a large multicenter pediatric cohort @ped-neph.bsky.social link.springer.com/article/10.1...

Interesting POV on new therapies in glomerular diseases in NDT #Free academic.oup.com/ndt/article/... What Jon Barratt calls palliative, others call supportive, these call ‘foundational’. RASi and Flozins ✅evidence for BP is opinion I think? But cost issues are huge, as shown here.

The defects in the Alport GBM allow plasma proteins to penetrate and become lodged or integrated, and they may interact with cellular receptors. Our data suggest that some of the mesangial matrix proteins in healthy mice come from the blood as well.

Glomerular basement membrane (GBM) structural integrity dictates trans-tissu... www.sciencedirect.com/science/arti... Really proud of this Cell Reports paper showing that the potentially pathogenic laminin alpha2 in the Alport GBM comes not from glomerular cells, but from the bloodstream.

Polygenic Risk Scores and HLA Class II Variants are Biomarkers of Corticosteroid Response in Childhood Nephrotic Syndrome doi.org/10.1016/j.kint.2026.01.026 #NephSky #MedSky #PedsNeph @dukemedschool.bsky.social @childrensphila.bsky.social @umnpeds.bsky.social @washunephrology.bsky.social

Upcoming Gordon Research Conference on ENDOTHELIAL CELLS Spain (July 5-10, 2026).The latest breaking topics in vascular biology focused on endothelial cells will be featured. Open slots reserved for oral presentations. Register early to reserve your spot. www.grc.org/endothelial-...

Dr. Kimberly A. Muczynski discusses her prolific research in Human Kidney Immunology. #nephsky #research #kidney #t-cells #microvascular #meded @uwmedicine.bsky.social Watch: youtu.be/6tMaASv1PBk

Very happy to share our new publication on the role of mitochondrial dynamics in endothelial cells and its implications for whole-body metabolism. kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

#Complement-Mediated Kidney Diseases: Role of #Alternative #Pathway in #Glomerular Inflammation https://doi.org/10.1016/j.ekir.2025.11.029#Complement-Mediated#Alternative#Pathway#Glomerular#KIRReview

Albumin plays a significant role in maintaining the body's balance 💙. Understanding proteins like albumin helps us better understand kidney health and conditions like nephrotic syndrome.

📣Friends!! Please check out 👀 🔥 www.abckidney.com Supported by @asnkidney.bsky.social Kidney Cure grant, it integrates durable learning theory into an immersive kidney physiology experience!! Follow here 👇👇 @abckidney.bsky.social 👀 us at YouTube 👇👇 @abckidney6240 - more to come soon 🤩

Proud today to share our latest work showing in vivo evidence that podocyte-derived ET-1 activating GEC ETA drives glomerular injury in FSGS. Congrats Liping Yu & @ubonge.bsky.social and big thanks to all co-authors for this tremendous team effort. #FSGS #nephrology #daehnlab @kidneyint.bsky.social

Podocyte derived endothelin-1 and endothelial cell endothelin A receptors are essential for glomerular injury in mouse models of focal segmental glomerulosclerosis doi.org/10.1016/j.kint.2026.01.014 #NephSky #MedSky #OpenAccess #FSGS

🚨 SAVE-THE-DATE 🚨 SEEON ANGIOSCIENCE! Fantastic, long-running meeting on Development & Maintenance of the Vasculature. 🗓️ Sept 2026 🌍 Bavaria, Germany Registration open! Join us! vwfb.de/start/regist...

Happy to share our latest work on endothelium and #nephroticsyndrome pubmed.ncbi.nlm.nih.gov/41659822/

🚀🌴💊 Early Bird Registration and abstract submissions are now OPEN for the 2026 ISGD Clinical Trials Summit in Galveston, TX! Join us in Nov. to advance innovative kidney research, find solutions to glomerular disease challenges, and shape the future of clinical trials. www.is-gd.org/cts-2026-reg...

moving on from IgAN to FSGS: BI 764198 a TRPC6 inhibitor reduces proteinuria in an N = 67 phase 2 RCT www.thelancet.com/journals/lan... in @thelancet.com #NephSky

Join our Clinical Trials Summit in Galveston, TX (Nov 13-15 2026) to advance innovative solutions in rare kidney disease trials. Registration & abstracts open Monday! www.is-gd.org/2026-cts @tobias-b-huber.bsky.social @utmbhealth.bsky.social Dr. Shikha Wadhwani Dr. Jochen Reiser

Effects of Empagliflozin on Urine Biomarkers in EMPA-KIDNEY bit.ly/3WA9uoy (OPEN ACCESS)

Low-grade proteinuria, whether assessed at baseline or over time, is an important predictor of kidney disease progression in patients with IgA nephropathy #IgAN ca. 2026 from @asnpublications.bsky.social #Nephpearls #NephSky 👉🏼 pubmed.ncbi.nlm.nih.gov/41385286/

How is podocyte injury and resultant nephropathy affected by endothelial cells? In a new paper led by @carafuentes-neph.bsky.social in @ScienceTM endothelial-derived CD93 was shown to be a key mediator of podocyte injury ✨ 👏🏼 thank you for including me in this project www.science.org/doi/10.1126/...

Happy Thursday! Registration remains open for ANCA-Vasculitis 2026: Diagnosis, Treatment & Comprehensive Care of Patients, taking place on Friday, March 6, 2026. Register today using the following link: www.eventleaf.com/AN...

Our large kidney transcriptomic dataset of #ANCA #glomerulonephritis is now publicly available (www.ncbi.nlm.nih.gov/geo/query/ac...). Used to describe a strong renal interferon signature and a prognosis signature outperforming current classifications (links below). I hope it will be useful! 🚀

interesting post hoc analysis from TESTING trying to identify which patients might benefit from steroids in IgAN (esp useful for markets where thats all we have!) www.kidney-international.org/article/S008... in @kidneyint.bsky.social #NephSky

🚀 Multiple open post-doc positions in our lab If you're a driven scientist with a strong interest in human genomics related to kidney disease & want to advance genetic discoveries, therapeutic hypotheses, & precision medicine for them, I hope you apply! tinyurl.com/kidneyomics-...

APOL1 high-risk variants predispose to CKD in people of African genetic ancestry due to podocyte toxicity; CAKUT have variable outcomes potentially driven by podocyte injury. Read this Original Article on APOL1 kidney risk variants & outcomes in children w/CAKUT. link.springer.com/article/10.1...

New systematic review and meta-analysis in #ASNCJASN: The Association between Low-Grade Proteinuria and Adverse Kidney Outcomes in IgA Nephropathy. Check it out: kidney.pub/CJASN0952

B Cell Depletion in Glomerular Diseases: Not Always as Safe as We May Think - Kidney Medicine www.kidneymedicinejournal.org/article/S259...

From a chance encounter years ago, far away, to this milestone today. Proud to have been involved in this research! Breakthroughs happen when we share ideas and challenge paradigms. Science moves forward when we work together—and this is just the beginning. #Nephrology #Research #TeamScience

In 2020, we started to question whether #idiopathicnephroticsyndrome is strictly a 'pure' podocytopathy. Today, I am happy to share our new manuscript proposing a role of the glomerular endothelium in the disease pathogenesis. urldefense.com/v3/__https:/...

Excited for this new opportunity! The UMN Department of Pediatrics has been my home for a long time and I’m honored to lead us through this transition.

excellent review of complement based therapies in ...IgA Nephropathy in @ajkd.bsky.social from @sstoneman.bsky.social et al www.ajkd.org/article/S027... Fig 1 with the 4-hit theory 1/

Around three weeks left to register for the 15th Annual Glomerular Disease 2026 Conference on Friday, February 6th, 2026. Feel free to register for our virtual conference using the following link: www.eventleaf.com/At...

Join us! NAVBO's virtual workshop🚀 Specification of EC Phenotypes Feb. 10-12 (12-4:30 PM ET). Learn more about EC's adaptability!! Can't join us? Recordings will be available to all registrants for one month after the meeting! See the full program and register here: www.navbo.org/feb2026/

Registration NOW Open for 'The 49th Annual Columbia Renal Biopsy Course’ - July 15-17, 2026 - an in-person & virtual program with ACCME credits & video access. Click for agenda, full details & registration: www.eventleaf.com/e/RenalBiops...

SMOC1, a matricellular protein, antagonizes EndMT in vitro IL-1β + TGFβ2 🐭Aortic arch greater vs lesser curvature 🐭Myocardial infarction How? SMOC1 binds to Endoglin ⏫Long-to-short Endoglin isoform ⏫BMP-SMAD1/5 ⏬TGFβ-SMAD2 Ingrid Fleming lab bioRxiv 2025 www.biorxiv.org/content/10.6...

By 2050, chronic kidney disease (CKD) is projected to become the fifth leading underlying cause of death worldwide. A new Seminar provides a simple approach to CKD diagnosis, staging, and management that can be applied in most clinical settings: spkl.io/63323AlsFF

The Italian Society of Nephrology expresses its deep sorrow for the passing of Prof. Claudio Ponticelli, a pioneer in nephrology and an outstanding scientist and mentor. Our heartfelt condolences to his family and colleagues. #RIP #Nephrology