The draft of @kdigo.org Clinical Practice Guideline for AKI/ AKD is now available for public review through 🗓️ April 27, 2026 #Nephpearls #NephSky We invite you to review the draft and share comments to help inform the final guideline 👉 kdigo.org/guidelines/a...

Did you know that the “four-hit” hypothesis for IgA nephropathy #IgAN was first clearly articulated by Hitoshi Suzuki et al. in their 2011 J. Am. Soc. Nephrol. paper, “The pathophysiology of IgA nephropathy.” #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/21949093/

Therapeutic targets 🎯and positioning of treatments in IgA nephropathy 🔬 #IgAN ca. 2026 from @kidneyint.bsky.social #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/41895685/

PISCES: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis ca. 2026 from @nejm.org @asnkidney.bsky.social #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/41201837/ 👉 www.kidneynews.org/view/journal...

Efficacy and Safety of Atrasentan in Patients with #IgAN Receiving Sodium-Glucose Cotransporter 2 Inhibitors (SGLT2i) ca. 2026 from @asnpublications.bsky.social #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Nephpearls #NephSky Photo Credit: @nephroseeker.medsky.social 👉 journals.lww.com/jasn/fulltex...

I made it to #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 ... well, kinda ... Photo Credit 👉 @hswapnil.medsky.social pubmed.ncbi.nlm.nih.gov/35155869/

Trying to catch up with #IgAN trials⁉️ Check out 👉 “IgAN: An Overview of the Clinical Trials” ca. 2025 from @kidneymed.bsky.social @haresh11.bsky.social @alexgr23.bsky.social @saynanorouzi.bsky.social #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/41050133/

SGLT2 inhibition: Pleiotropic direct cardiac and kidney effects ⁉️ #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Nephpearls #NephSky 👉🏼 pubmed.ncbi.nlm.nih.gov/35589167/

The draft of the @kdigo.org 2026 Clinical Practice Guideline for Acute Kidney Injury and Acute Kidney Disease is now available for public review through 🗓️ April 27, 2026 #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Nephpearls #NephSky 👉 kdigo.org/guidelines/a... 👉 FEEDBACK Form www.surveymonkey.com/r/GTGNFHG

Approach to immune checkpoint inhibitor (ICI) nephrotoxicity and rechallenge #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Onconephrology 🦀 #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/32775813/

Diagnostic approach to hypophosphatemia #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/34754427/

Practical suggestions for the diagnosis and management of hypertension before, during, and after the start of anticancer therapy #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Onconephrology 🦀 #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/36621810/

Cancer Therapy Related Hypertension #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Onconephrology 🦀 #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/36621810/

Pathogenesis of IgA Nephropathy #IgAN #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/37742867/

Hypomagnesemia 📌 Manifestations and its association with cancer 📌 Causes in patients with cancer #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Onconephrology 🦀 #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/37086496/

Individualized management of malignancy-associated hypercalcemia #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Onconephrology 🦀 #Nephpearls #NephSky 👉🏼 pubmed.ncbi.nlm.nih.gov/41623290/

Pillars of IgA Nephropathy #IgAN Treatment #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Nephpearls #NephSky 👉🏼 pubmed.ncbi.nlm.nih.gov/38398259/

Pillars of Treatment for Diabetic Kidney Disease secondary to Type 2 Diabetes (T2D) #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Nephpearls #NephSky 👉🏼 medicinetoday.com.au/mt/2024/dece...

Timely publication on "@asnkidney.bsky.social Kidney Health Guidance on Conservative Management in People with Kidney Failure" ca. 2026 from @asnpublications.bsky.social #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/41848800/

Cardiovascular-Kidney-Metabolic (CKM) Syndrome Stages: Identify Chronic Kidney Disease (CKD) as an important risk ⚠️ for adverse outcomes #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/37807924/

If you're attending #WCN26 🇯🇵 #WCN2026 🇯🇵 do not miss @kdigo.org Guideline Education Meeting (GEM) #KDIGOGEMS 💎 #Nephpearls #NephSky 🗓️ Friday, March 27, 2026 ⏰ 09:00 – 16:00 JST 📍 Room 303, Pacifico Yokohama Conference Center Learn more: kdigo.co/WCN26-KDIGO-...

A focused update to @kdigo.org 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease (CKD) has been initiated #Nephpearls #NephSky 📌 The update will focus on "Delaying CKD progression and managing its complications” 👉 www.surveymonkey.com/r/P9GHNBY

The draft of @kdigo.org 2026 Clinical Practice for Diabetes and Chronic Kidney Disease (CKD) is available for public review through 🗓️ April 13, 2026 #Nephpearls #NephSky We invite you to review the draft and share comments to help inform the final guideline 👉 kdigo.org/guidelines/d...

📢 New in #ASNJASN: ASN Kidney Health Guidance on Conservative Management in People with Kidney Failure. The guidance affirms conservative management as a proactive care option and addresses tailored CKD care, symptom management, and care transitions. 🔗kidney.pub/JASN1068

Randomized Double-Blind Trial of #WS016 in #Chinese Patients With #Hyperkalemia #VisualAbstract by Edgar V. Lerma 🇵🇭 https://www.kireports.org/article/S2468-0249(26)02589-1/fulltext

Systematic Review of #Immunosuppression after #CAR-T Therapy for #PTLD #VisualAbstract by Edgar V. Lerma 🇵🇭 https://www.kireports.org/article/S2468-0249(26)02598-2/fulltext

UACR (urinary albumin-to-creatinine ratio) can direct personalized prevention and treatment for cardiovascular (CVD) and chronic kidney disease (CKD) ca. 2026 #Nephpearls #NephSky 👉🏼 pubmed.ncbi.nlm.nih.gov/41633942/

In conjunction w/ @theisn.org World Congress of Nephrology & Tokushukai Medical Group, @kdigo.org will host a full-day Guideline Education Meeting (GEM) #ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵 #Nephpearls #KDIGOGEMS 💎 #NephSky 👉🏼 kdigo.org/events/kdigo...

Is AI really the future of Medicine? 📌 The study involved 100 patients interacting via text chat w/ AMIE before in-person visits, showing 90% inclusion of final diagnoses in AMIE's differential lists & comparable quality to PCP's plans (p>0.05 for differences) 👉🏼 arxiv.org/abs/2603.08448

Hypomagnesemia (Outpatient): Diagnostic algorithm from @kidneyboy.bsky.social #Nephpearls #NephSky 👉 shop.lww.com/Manual-of-Ne...

Happy #WorldKidneyDay‼️#SockItToKidneyDisease 🧦🕷🕸#NationalKidneyMonth #NephSky

Diuretic management in patients w/ kidney AKI & acute heart failure ca. 2026 from @kdigo.org @kidneyint.bsky.social #Nephpearls #Cardiorenal #NephSky 📌 This algorithm provides a list of what to look for when assessing optimal response to a diuretic regimen 👉 pubmed.ncbi.nlm.nih.gov/41791738/

Conceptual framework for the medical management of heart failure (HF) with reduced or preserved ejection fraction (HFrEF or HFpEF) and chronic kidney disease (CKD) ca. 2026 from @kdigo.org @kidneyint.bsky.social #Nephpearls #Cardiorenal #NephSky 👉 pubmed.ncbi.nlm.nih.gov/41793402/

GDMT for HFpEF and HFrEF #Nephpearls #Cardiorenal #NephSky 👉🏼 www.acc.org/Education-an...

Check out our review "IgA Nephropathy #IgAN: An Overview of the Clinical Trials" #Nephmadness write up #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/41050133/ 👉 NephMadness ajkdblog.org/2026/03/01/n...

C3 Glomerulopathy Diagnosis, Current Treatments, and Emerging Therapies ca. 2026 from @kidneymed.bsky.social @saynanorouzi.bsky.social 📢 This paper is a very timely read for #NephMadness #Nephpearls #NephSky 👉🆓 www.sciencedirect.com/science/arti... 👉 ajkdblog.org/2026/03/01/n...

It’s March once again … #Nephmadness has begun #Nephpearls #NephSky 👉🏼 ajkdblog.org 👉🏼 If you don’t know what it’s about, then it’s time to checkout this 📺 m.youtube.com/watch?v=tZUR...

C3 Glomerulopathy Diagnosis, Current Treatments, and Emerging Therapies ca. 2026 from @kidneymed.bsky.social @jzrenalpath.bsky.social @drraymondhsu.bsky.social @saynanorouzi.bsky.social #Nephpearls 👉 www.sciencedirect.com/science/arti...

Which patients with CKD should be on SGLT2 inhibitors (SGLT2i) ⁉️ #Nephpearls #NephSky ✅ Check out our Cold 🥶 map from @theisn.org @isnkidneycare.bsky.social 👉 www.theisn.org/initiatives/...

Dialysis Dysequilibrium Syndrome #Nephpearls #AKIinICU #NephSky 📌 Reverse Urea Hypothesis 📌 Idiogenic Osmole Hypothesis 📌 High Dialysate Bicarbonate 👉 shop.lww.com/Handbook-of-...

Real-World Hospitalization Outcomes with On-Line Hemodiafiltration Versus High-Flux Hemodialysis ca. 2025 from @asnpublications.bsky.social #Nephpearls #NephSky #VisualAbstract by @husamjz.bsky.social 👉 pubmed.ncbi.nlm.nih.gov/41433104/

Flowsheet for the potential escalation of diuretics in patients with refractory hypervolemia #Nephpearls #Cardiorenal #NephSky 👉 www.wolterskluwer.com/en/solutions...

Capillary refill time (CRT) measured in digital nail bed blood return is quick, easily performed, and a long-standing component of the physical exam in the ICU #Nephpearls #AKIinICU #NephSky 👉 www.wolterskluwer.com/en/solutions... 👉 pubmed.ncbi.nlm.nih.gov/30772908/

Simultaneous initiation of finerenone and empagliflozin was effective and well tolerated among CONFIDENCE study participants from Asia, consistent with the overall population ca. 2026 from @asnpublications.bsky.social #Nephpearls #NephSky 👉 pubmed.ncbi.nlm.nih.gov/40965042/

New terminology for iron deficiency in CKD ca. 2026 from @kdigo.org #Nephpearls #NephSky Systemic iron deficiency (previously Absolute iron deficiency) ⬇️ Ferritin ⬇️TSAT​ Iron-restricted erythropoiesis (previously Functional iron deficiency) ⬆️ Ferritin ⬇️ TSAT​ 👉 kdigo.org/guidelines/a...

Super Bowl 🏈 LX commercial highlighting UACR #Nephpearls #NephSky #SuperBowlLX youtu.be/GO6Lq8lLlVU?...

Iron treatment may be considered in people with CKD and profound iron deficiency (ferritin <30 ng/ml [<30 mg/l] and TSAT <20%) in the absence of anemia, especially in the presence of symptoms ca. 2026 from @kdigo.org #Nephpearls #NephSky 👉 kdigo.org/guidelines/a...

Low-grade proteinuria, whether assessed at baseline or over time, is an important predictor of kidney disease progression in patients with IgA nephropathy #IgAN ca. 2026 from @asnpublications.bsky.social #Nephpearls #NephSky 👉🏼 pubmed.ncbi.nlm.nih.gov/41385286/

Editors’ Choice 2025: Efficacy and Safety of Ravulizumab in IgA Nephropathy: A Phase 2 Randomized Double-Blind Placebo-Controlled Trial This phase 2 trial tested ravulizumab, a complement C5 inhibitor, in adults with IgA nephropathy. Check out the paper here: kidney.pub/JASN0534

Although often used interchangeably, dehydration & volume depletion are not the same #Nephpearls #NephSky 📌 Dehydration refers to “loss of total body water” (leads to hypertonicity) 📌 Volume depletion refers to an ECFV deficit 👉🏼 pubmed.ncbi.nlm.nih.gov/21705120/