In our latest #Collidescope episode, Dr. Charles and Dr. Boyd investigate a myoglobin and hemoglobin cast collision case. What happens when two diseases occur at the same time? Does one influence the other? How is kidney function affected? #renalpath #nephrology

Could a single immune protein link kidney and heart disease? 🧬 New research suggests suPAR not only signals risk but may drive organ damage. Curious about its role as both biomarker and therapy target? Read more: www.news-medical.net/news/2026010... #Cardiology#Inflammation @jci.org

This is the H&E from the frozen tissue submitted for IF examined under fluorescent light. In a patient with anemia, thrombocytopenia, high LDH and schistocytes, what is your diagnosis?    #DiagnoseThis #nephsky #pathsky #renal #kidneypath

The role of suPAR and related proteins in kidney, heart diseases, and diabetes In this Review, Jochen Reiser & team highlight the soluble form of the urokinase plasminogen activator and its related proteins beyond their prognostic value as markers of inflammation: doi.org/10.1172/JCI1...

Quality-oriented diet therapy for chronic kidney disease | Nature Reviews Nephrology - goo.gl/alerts/dWDC5K #GoogleAlerts

In our latest #Collidescope episode, Dr. Charles and Dr. Boyd investigate a myoglobin and hemoglobin cast collision case. What happens when two diseases occur at the same time? Does one influence the other? How is kidney function affected? #renalpath #nephrology

Pregabalin Toxicity in Kidney Failure: A Medication Error With Neurological Consequences - goo.gl/alerts/XbD3yo #GoogleAlerts

New year, new publication. Great working on this article on sepsis-associated AKI with @shinamenon.bsky.social, Pavan Bhatraju, and Javier Neyra. Currently, free to access. #nephsky #emimcc @uwnephrology.bsky.social authors.elsevier.com/a/1mNWkzzky3...

Morning Bluesky.

It's 2026!🎉 We will be counting down the Top Ten Nephrology Stories of 2025 on 1/6/26 at 9 pm EST. Join us on TWITTER (it will always be Twitter to us). Come on by #NephJC faithful for a lively discussion! You picked & we're count'em down. www.nephjc.com/news/2025/1/3/top-stories-in-nephrology-2025

#nephJC #MedSky #NephSky

The importance of treatment sequencing with SGLT2 inhibitors and GLP-1 receptor agonists combination for kidney function preservation in type 2 diabetes #nephsky #nephrology dom-pubs.onlinelibrary.wiley.com/doi/10.1111/...

A new study by researchers from Stony Brook University's Renaissance School of Medicine identifies a protein that helps drive kidney inflammation and points to a potential new way to slow damage in chronic kidney disease. https://bit.ly/497UR1t

Management of anemia in CKD ca. 2026 from @kdigo.org #Nephpearls #NephSky 👉 kdigo.org/guidelines/a...

Wow - excellent discussion of the totally underwhelming BICAR-ICU2 trial podcasts.apple.com/ca/podcast/f... @nephcrit.bsky.social fighting a line fight against the unimpressed nephrons with guest @weddellite.bsky.social #NephSky #EMIMCC

Full‐House Nephropathy Without Lupus Manifesting During Acute Kidney Allograft Rejection: A Case Report #nephsky #nephrology pmc.ncbi.nlm.nih.gov/articles/PMC...

ACE inhibitor fetopathy - still with us...

Can’t get more surprising!

Classification of glomerular diseases based on main pathogenic 🔬 mechanisms #Nephpearls #NephSky 👉 shop.lww.com/Handbook-of-...

Call for routine high blood pressure testing of UK children as cases almost double www.theguardian.com/society/2026...

This is the biopsy of a 68F with a history of bone marrow transplant and AKI. What is your diagnosis? #DiagnoseThis #nephsky #pathsky #renal #kidneypath

New call to action: Chronic kidney disease (CKD) screening can help reduce cardiovascular risk and improve outcomes. Early detection and intervention are key. 🔗 https://ow.ly/YXWE50XQ4IJ #CKD #HeartHealth #PreventiveCardiology #CVDPrevention #PublicHealth #CardioSky #MedSky

Identification of Potential FSGS through Evaluation of Parietal Epithelial Cells Status Changes Using Integrin α3 Immunostaining #nephsky #nephrology www.sciencedirect.com/science/arti...

A very rare cause of oliguric acute kidney disease: crescentic C3 glomerulopathy Open Access #nephsky #nephrology academic.oup.com/omcr/article...

Intermittent haemodialysis declined while continuous renal replacement therapy became increasingly common in French ICUs between 2008 and 2019. zurl.co/T3d1q

Before the Pressure Rises Intrarenal Renin-Angiotensin-Aldosterone System Activation in Normotensive Autosomal Dominant Polycystic Kidney Disease #nephsky #nephrology journals.lww.com/kidney360/fu...

Trump's NIH canceled a study on how structural racism adds to genetic risk in kidney disease, saying it “didn’t show a sufficient return on investment.” To Robert Sanchez, this showed "how some in this country devalued my life and the lives of people in my community." www.ajkd.org/article/S027...

I don’t know about the quality of this trial, I’ve found just the abstract. pubmed.ncbi.nlm.nih.gov/17514629/

Kappa-type light chain proximal tubulopathy On EM, low mag shows membrane-bound crystalline-like cytoplasmic inclusions but up close has fibrillar appearance. 🔹Congo-red is negative 🔹Reported w/ MGUS, MM, & lymphoma 🔹Most had fanconi syndrome #MGRS #renalpath #pathsky #nephsky #nephrology (1/2)

Utility and limitations of the use of donor-derived cell-free DNA in kidney transplantation #nephsky #nephrology europepmc.org/article/med/...

Pig organ transplants could one day be superior to human ones, says expert | Medical research https://www.europesays.com/ie/252269/ A leading surgeon behind a clinical trial of transplanting pig kidneys into living humans has said they could…

Agree - it seems similar to MARS (which never took off hugely) - I think in this case albumin is not recirculated though. Their previous attempt here www.sciencedirect.com/science/arti... An RCT is fine to do Any other comments @ebtapper.bsky.social ?

Tis the season for christmas kidney cookies! Happy Holidays

Bisphosphonates' Impact on Kidney Function in Elderly Osteoporotics - BIOENGINEER.ORG - goo.gl/alerts/a689p4 #GoogleAlerts

Mitochondrial DNA Analysis Should Be Considered in the Genetic Assessment of FSGS or Unexplained Chronic Kidney Disease: A Case Report #nephsky #nephrology www.kidneymedicinejournal.org/article/S259...

Nephrotic syndrome genomic discovery in the Mass General Brigham Biobank identifies monoallelic MEFV variants as a risk factor for focal segmental glomerulosclerosis #nephsky #nephrology www.kidney-international.org/article/S008...

(1/5) Day 2: Although the findings of membranous (RPS class V) lupus nephritis (LN) are not technically scored by the modified NIH activity index system, it is a variant of LN which occurs with significant proteinuria and potential loss of renal function... #lupus #pathsky #nephsky

Scientists are generating more slop than ever!

New out today: Antiproteinuric Effect of Sparsentan in Patients with Genetic-Associated FSGS Enrolled in the DUPLEX Trial Genetic FSGS CAN be treated. journals.lww.com/cjasn/abstra...

What are your differential diagnosis for this ultrastructural finding? #DiagnoseThis #nephx #pathx #renal #kidneypath

We are pleased to share the conference report from the KDIGO Controversies Conference on Obesity and CKD, now published in @kidneyint.bsky.social. Read the report: kdigo.co/Obesity-CKD-... Read the news release: kdigo.co/Obesity-CKD-... Learn more: kdigo.org/conferences/... #obesity #CKD

1/n young adult gets transferred to our hospital for higher level of care. Had presented to a rural institution with weakness; found to have Hgb 7.5, serum Cr 2.6 mg/dL, hematuria. Prompted a positive p-ANCA. Nephrology is consulted on arrival

And we start 2026 off with a bang. Oral Wegovy is now approved in the United States for obesity. Now will the demand be there? Will it be priced cheap enough? Will insurance cover it(Probably not...) Will patients follow the weird dosing regimen? Things are heating up again in the GLP1 world.

Increased fluid intake and blood pressure in healthy children: a randomized controlled trial. The SPA Project #nephsky #nephrology link.springer.com/article/10.1...

Thanks to @jefftiedrich.bsky.social and @rubinallergy.bsky.social for keeping urine ingestion topical. This is NOT what the kidney community considers the cutting edge of nephrology, but that's where Oz, RFK Jr, Makary, Prasad, et al are leading us. @hswapnil.medsky.social

Precision approaches to paediatric hypertension: linking pathophysiology to therapy #nephsky #nephrology link.springer.com/article/10.1...

COVID‐19‐Positive Kidney Transplant Recipients C19+ KTRs demonstrated substantially increased susceptibility to Mycoplasma pneumoniae & Chlamydia pneumoniae coinfections compared with their COVID‐19‐negative counterparts @OrganspendeBZgA @ProTransplant ... onlinelibrary.wiley.com/doi/pdf/10.1...

12 Days of Lupus Scoring Findings Countdown! Day 7: This last activity index score is focused on the tubulointersitium. To be included in the scoring, the inflammation cannot be chronic (I.e. needs to be outside areas of interstitial fibrosis/ tubular atrophy). #lupus #pathology #nephrology (1/3)

New phase 3 data from the ATTAIN-MAINTAIN trial. #NephSky #Obesity #GLP1 lilly.mediaroom.com/2025-12-18-L...