I have no idea which of the 8 disks RHEL decided to install itself at. #FAFO

Food should provide pleasure. This lunch is an abomination.

Grab popcorn as the premiums of the individual healthcare plans for 2026 are announced. Looking at the number of layoffs and the age distribution of those being laid off, many more people will have to transition from an employer to a pricey individual plan during the midterms.

Paneer and queso Blanco are edible and don't have the texture of goat poop.

Cottage cheese = kale of milk derivatives Now you know

This is where it gets interesting : at a word size of 1 bit, multiplication is just logical and. So is all multiplication just logical conjunction? First principle derivation of probability as degrees of certainty rely precisely on this connection @stephensenn.bsky.social @cubiclogic.bsky.social

Incretins are the G-force : Guardians of (Inner) Space(*). No more glipination @hswapnil.medsky.social @mikejohansenmd.medsky.social @rnflex.bsky.social,only G force (*)a reference to the 1980s US adaptation of the 1972 Japanese anime Gatchaman but feel free to substitute the 2009 guinea pig movie

Packing Costco lunch because inflation, weight loss and intermittent fasting (which is just caloric restriction)

As one of the original flozinators it so maddening to see nephrologists flozinate *instead* of using immunosuppresants, dz modifying therapies in nonDM CKD. Consider a thought experiment in transplant: proteinuria is often how we pick up ABMR & an SGLT2i is the wrong answer. Now do IgAN, SLE,C3G etc

Typhoon Kalmaegi exposes centuries-old shipwreck off Vietnam port ⛏️⚓️🇻🇳 www.channelnewsasia.com/asia/typhoon...

Fascinating paper suggesting the assumption that there is a sigmoid dose response relationship and threshold effect ( "all-or-nothing") for loop diuretics rests on repeated misinterpretation of original studies from the 70s and 80s. #nephsky #cardiosky #emimcc academic.oup.com/ehjcvp/artic...

Nailed it

Bahahahahaha The New York Times just printed an opinion piece declaring "AI is intelligent, so long as we redefine what intelligence means to include it. And soon AI will be conscious, because we'll just redefine consciousness too!" Nothing means anything! Yay! www.nytimes.com/2025/11/08/o...

Tech guys six months ago: haha yes we’re cutting all this WASTEFUL spending by eliminating medical research and USAID Tech guys now: yes I think taxpayers will be excited to bailout my non consensual pornography machine

Axios tried to bust James Talarico for following adult content creators on Instagram and I'm genuinely impressed by his campaign's response

Busting some delusions about #longcovid open.substack.com/pub/christos... (Also on X/Twitter and Mastodon)

I loved this enough to have a 🔥: daily eval for need for dialysis for #AKI leads to shorter need for dialysis as opposed to forgetting people on dialysis until the reality of recovery smacks you hard. The LIBERation from AcuTE Dialysis (LIBERATE-D) Randomized Clinical Trial #KidneyWk ja.ma/48Ngo0W

I am always fashionably late when I time travel

China lifted its import ban on Illumina’s DNA sequencers after trade talks, reopening a key market even as it remains on the ‘unreliable entities’ list.

wouldn't a beaver buffet be wood? seems counterintuitive haha

A Colorado woman grabbed food from a Dumpster when the food bank was empty. Down to $1.18: How Families Are Coping With SNAP Cuts www.nytimes.com/2025/11/07/u...

Lord, have mercy

Word of the Day is ‘catchfart’ (17th century): an obsequious individual who sucks up to the boss and always follows the political wind.

Until next year leaves (but at this stage, every leaf is a flower as a philosopher one said)

Strong Trantor vibes now

Perfect example of an LLM output of coherent parts (sentences) summing up to an incoherent whole (paragraph). Imagine this playing out at a larger scales by those who have adopted these noisy stochastic parrots at scale.

Now that FINE-ONE has shown that #finerenone ⬇️ proteinuria in #ckd w type 1 diabetes #t1d, it'll be difficult for insuranfe companies to deny. But what about the egfr trajectories shown today at #kidneywk? Reflective of false stabilization of egfr on placebo or something else?

What a great idea. 😆

Question: How much of normalized ovarian decline in human is due to viruses?

It would be a touch ironic if ai killed the USA through a financial crisis.

I repurposed my old LG V20 as a portable usable small tablet as it has a wider screen than the LG I am using as a phone (and it has a removable battery). LG had a very solid smartphone line that fell prey to the marketing strategy of its competitors.

Yes yes yes. It's so frustrating! Even starting a low key blog like I did was my way to try and push back on the void of slop

It is not just online spaces. I simply refuse to buy books published after 2023 unless there are second editions of known quantities.

Just in time for Thanksgiving. www.cnn.com/2025/11/05/u...

Machine perfusion is better than just cold storage for kidneys 10 year follow up of the original 2009 trial in the @nejm.org www.nejm.org/doi/full/10.... #NephSky #KidneyWk

Don't get to see much on X/Twitter about the election results. People left or #grokedsuddenly?

Many professionals who were posting under their own name actually went to LinkedIn after twitters decline during the election. It makes sense to go there if not anonymous

I actually do want a data center in my backyard so bad I want to grow numb to the endless drone of a million electronic beehives I want to get testicular cancer from people I’ll never meet generating shrek porn in their basements

Me: I wonder why Lilly is running trials for orforglipron (oral GLP-1 med) for hypertension?? Sees this slide today at Obesity Week: OH. (that placebo reduction is presumably rescue therapy of prescribing traditional blood pressure meds) So yeah impressive reductions.

Prediction: the 2026 primary season is going have some wild results.

Just a call out to smart women helping the entire world. This is Lotte Bjerre Knudsen. She invented liraglutide and co-invented semaglutide. She is one of the biggest reasons we have effective anti obesity medications. And her sense of style for this talk is 🤌

Following all of the software engineering, data engineering, etc subreddits is really depressing right now because all anyone talks about is a) how bad hiring is, and b) how bad the actual work itself is now due to dealing with LLMs in the workplace.

It is insane, that #Intel kneecapped i7's for scientific work. The 11th gen i7 offered the AVX512 instruction set which DOUBLED throughput compared to the 10th 7 the 12th gen. To get the same throughput that this i7 delivers in our RNAseq workflows, one has to pay $$$ for a Xeon

I feel seen

Job openings have dropped to their lowest level since February 2021, according to Indeed.

I am getting ready to become an LLM: Lunatic of LinkedIn and Maniac.

FWIW, we pay clown college stipends #clown #phd

Our #Covid19 work in #KidneyWk : > transplant fx over time doi.org/10.1681/ASN.... > kidney fx over time doi.org/10.1681/ASN.... > AKI doi.org/10.1681/ASN.... > #C3GN doi.org/10.1681/ASN.... > #IgAN doi.org/10.1681/ASN.... > dialysis vasc access doi.org/10.1681/ASN.... TLDR: don't get covid

I am honestly impressed by the SIMDe (SIMD everywhere) library github.com/simd-everywh... It simplified some #bioinformatics relevant code I am writing since I don't have to develop my macros to run across x86/ARM and hopefully RISCV. SIMDEe plays well as backend to #Perl for extreme portability!