Grace Choung, MD 박영이
@gracechoung.bsky.social
📤 146
📥 185
📝 61
Renal pathologist @CedarsSinai
#renalpath
#kidneydisease
opinions are my own
Bone Marrow Examination in Proliferative Glomerulonephritis with Monoclonal Ig Deposition: A Serology-Based Approach - Kidney International Reports
www.kireports.org/article/S246...
#pathsky
#nephsky
#nephrology
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Bone Marrow Examination in Proliferative Glomerulonephritis with Monoclonal Ig Deposition: A Serology-Based Approach
Recent data indicate that nearly 80% of cases of proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) lack a monoclonal etiology, as shown by sensitive immunoglobulin repe...
https://www.kireports.org/article/S2468-0249%2826%2902576-3/fulltext
about 3 hours ago
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reposted by
Grace Choung, MD 박영이
American Journal of Kidney Diseases
11 days ago
#RenalPath
: Glomerulonephritis with dominant C3 showing contour duplication of glomerular basement membranes (Jones silver stain).
bit.ly/2Jto75d
(FREE)
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reposted by
Grace Choung, MD 박영이
American Journal of Kidney Diseases
4 days ago
#RenalPath
Immunotactoid Glomerulopathy
bit.ly/4q8NHAk
(FREE)
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reposted by
Grace Choung, MD 박영이
Edgar V. Lerma 🇵🇭
2 days ago
Low-grade proteinuria, whether assessed at baseline or over time, is an important predictor of kidney disease progression in patients with IgA nephropathy
#IgAN
ca. 2026 from
@asnpublications.bsky.social
#Nephpearls
#NephSky
👉🏼
pubmed.ncbi.nlm.nih.gov/41385286/
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reposted by
Grace Choung, MD 박영이
Kidney International
2 days ago
Heat shock protein 70s are modifiers of endothelial function in Fabry disease
doi.org/10.1016/j.kint.2026.01.004
#NephSky
#MedSky
#OpenAccess
@umichmedicalschool.bsky.social
@omrf.bsky.social
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reposted by
Grace Choung, MD 박영이
Kidney International
2 days ago
Intermittent dark urine in a school-aged boy: a case of alkaptonuria
doi.org/10.1016/j.kint.2025.07.035
#NephSky
#MedSky
#PedsNeph
#PathSky
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reposted by
Grace Choung, MD 박영이
5 days ago
T-cell lymphoblastic lymphoma presenting with type B lactic acidosis and acute kidney injury in an adolescent
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T-cell lymphoblastic lymphoma presenting with type B lactic acidosis and acute kidney injury in an adolescent - Pediatric Nephrology
Acute kidney injury (AKI) in children is a major cause of morbidity and mortality and is most commonly associated with dehydration, sepsis, or nephrotoxic exposures. In rare instances, however,…
https://buff.ly/U006xXp
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reposted by
Grace Choung, MD 박영이
Hemily Zandybell, MD
5 days ago
Female, 40 yo, LES class IV, cr 3.11 (previous 0.8), hematuria, proteinuria. U-Sed: RBC cast, presence of leukocytes (glitter cells?)
#Urinarysediment
#urineMicroscopy
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The long and the short of it: how CUBN isoforms are affected by genetic variants - Kidney International Reports
www.kireports.org/article/S246...
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The long and the short of it: how CUBN isoforms are affected by genetic variants
The loss of proteins into the urine (proteinuria) is an important risk factor for renal and cardiovascular disease. In particular, albuminuria is associated with an increased risk of chronic kidney di...
https://www.kireports.org/article/S2468-0249%2826%2900034-3/fulltext
5 days ago
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Persistent ANCA Positivity in Granulicatella adiacens-associated Endocarditis: Diagnostic Implications of Methodological Variability - Kidney International Reports
www.kireports.org/article/S246...
#pathsky
#nephsky
#nephrology
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Persistent ANCA Positivity in Granulicatella adiacens-associated Endocarditis: Diagnostic Implications of Methodological Variability
We read with great interest the article by Andeen et al.1 on Bartonella endocarditis–associated glomerulonephritis as a mimicker of autoimmunity and vasculitis. Although antineutrophil cytoplasmic aut...
https://www.kireports.org/article/S2468-0249%2825%2900752-1/fulltext
5 days ago
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reposted by
Grace Choung, MD 박영이
American Journal of Kidney Diseases
7 days ago
Collagenofibrotic Glomerulopathy Associated With Homozygous STAB2 and Heterozygous STAB1 Variants: A Case Report
bit.ly/4k5WTnG
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reposted by
Grace Choung, MD 박영이
Kidney International
7 days ago
Genotype-phenotype characteristics and disease progression of FAN1-related karyomegalic tubulointerstitial nephropathy
doi.org/10.1016/j.kint.2026.01.001
#OpenAccess
#NephSky
#MedSky
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reposted by
Grace Choung, MD 박영이
IPNA Pediatric Nephrology
7 days ago
AKI in children is a major cause of morbidity & mortality & is associated w/dehydration, sepsis, or nephrotoxic exposures. Read these Clinical Insights into T-cell lymphoblastic lymphoma presenting w/type B lactic acidosis & AKI in an adolescent.
link.springer.com/article/10.1...
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reposted by
Grace Choung, MD 박영이
IPNA Pediatric Nephrology
14 days ago
BK polyomavirus–associated nephropathy is a challenge in kidney transplant recipients, often leading to allograft dysfunction. Read these Clinical Insights into treatment of severe, refractory polyomavirus disease in a pediatric kidney recipient.
link.springer.com/article/10.1...
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reposted by
Grace Choung, MD 박영이
13 days ago
Interesting review about membranous nephropathy. It presents five interesting clinical cases highlighting the utility of antigen identification in guiding the management of membranous nephropathy.
@ajkd.bsky.social
DOI: 10.1053/j.ajkd.2025.08.013
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reposted by
Grace Choung, MD 박영이
Swapnil Hiremath 🍁🇨🇦
12 days ago
steroid reduction in GN
www.kireports.org/article/S246...
excellent review by ottawa GN group in
@kireports.bsky.social
@michael-toal.bsky.social
and team
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reposted by
Grace Choung, MD 박영이
ASN Publications
13 days ago
New in #ASNCJASN: "Natural History and Clinical Associations with Long-Term Outcomes in Primary C3 Glomerulopathy and Immune Complex-Mediated Membranoproliferative Glomerulonephritis" Read the article here:
kidney.pub/CJASN0953
Maddalena Marasà
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reposted by
Grace Choung, MD 박영이
Jonathan Zuckerman MD PhD
12 days ago
Classic global granular capillary wall staining with IgG in this case of membranous nephropathy.
#renalpath
#pathsky
#nephsky
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The pathophysiological mechanism of Beni-koji Choleste-Help/puberulic acid-induced kidney injury - Kidney International Reports
www.kireports.org/article/S246...
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The pathophysiological mechanism of Beni-koji Choleste-Help/puberulic acid-induced kidney injury
In March 2024, kidney injury caused by some specific red yeast rice supplements was reported in Japan. By November 2024, 2,628 people had visited medical facilities, making it a social problem. Many p...
https://www.kireports.org/article/S2468-0249%2826%2900024-0/fulltext
12 days ago
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Update on Alport syndrome: the report of the 2024 International Workshop on Alport syndrome - Kidney International Reports
www.kireports.org/article/S246...
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Update on Alport syndrome: the report of the 2024 International Workshop on Alport syndrome
The 2024 International Workshop on Alport syndrome brought together people living with Alport Syndrome, clinicians, laboratory scientists, and representatives from pharmaceutical companies to present ...
https://www.kireports.org/article/S2468-0249%2826%2900016-1/fulltext
12 days ago
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reposted by
Grace Choung, MD 박영이
IPNA Pediatric Nephrology
14 days ago
Proteinuria is a common finding in adolescents. It's often benign, but it can be an early sign of underlying conditions that may lead to long-term kidney damage. Read this Educ Review of the diagnostic approach to proteinuria in adolescents.
link.springer.com/article/10.1...
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reposted by
Grace Choung, MD 박영이
haysamrady
14 days ago
Congophilic fibrillary glomerulonephritis recurrence post-renal transplant: diagnostic challenges and proteomic insights
#nephsky
#nephrology
link.springer.com/article/10.1...
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Congophilic fibrillary glomerulonephritis recurrence post-renal transplant: diagnostic challenges and proteomic insights - CEN Case Reports
CEN Case Reports - Fibrillary glomerulonephritis (FGN) is a rare kidney disease characterized by the deposition of Congo red (CR) negative fibrils measuring 12 to 24 nm in diameter on...
https://link.springer.com/article/10.1007/s13730-025-01064-4
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reposted by
Grace Choung, MD 박영이
Jonathan Zuckerman MD PhD
13 days ago
Young F pt with nephrotic range proteinuria. Membranous pattern injury with near negative frozen IF. Pronase IF unmasks IgG-K staining. SAP is positive. Membranous-like glomerulopathy with masked IgG-kappa deposits.
pubmed.ncbi.nlm.nih.gov/32001064/
#renalpath
#nephsky
#pathsky
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A Pathway to High Quality Clinical Trials in IgA Vasculitis Nephritis: Meeting Proceedings From a Multiprofessional International Collaborative Workshop - Kidney International Reports
www.kireports.org/article/S246...
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A Pathway to High Quality Clinical Trials in IgA Vasculitis Nephritis: Meeting Proceedings From a Multiprofessional International Collaborative Workshop
IgA vasculitis (IgAV) is an autoimmune disease that affects the small vessels of the skin, joints, gastrointestinal (GI) tract, and kidneys. In the long term, IgAV associated with nephritis (IgAV-N) c...
https://www.kireports.org/article/S2468-0249%2825%2900747-8/fulltext
13 days ago
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reposted by
Grace Choung, MD 박영이
Swapnil Hiremath 🍁🇨🇦
15 days ago
#NephGR
tomorrow!
@sbrimble.bsky.social
on TMA in cancer and the St Joe’s Hamilton onconephrology program
#NephSky
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reposted by
Grace Choung, MD 박영이
Jonathan Zuckerman MD PhD
14 days ago
Case of IgAN with massive hemispherical mesangial deposits. Mimics cryo-plugs but deposits are mesangial rather than filling capillary loops.
#renalpath
#pathsky
#nephsky
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Pauci-Immune Endocapillary Proliferative GN with Glomerular M2 Macrophage Infiltration - Kidney International Reports
www.kireports.org/article/S246...
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Pauci-Immune Endocapillary Proliferative GN with Glomerular M2 Macrophage Infiltration
Pauci-immune Endocapillary Proliferative Glomerulonephritis (Pauci-I-EPGN) is a rare glomerular disease with a heterogeneous and poorly understood etiology. Here we describe the clinicopathological fe...
https://www.kireports.org/article/S2468-0249%2826%2900022-7/fulltext
14 days ago
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reposted by
Grace Choung, MD 박영이
Jonathan Zuckerman MD PhD
16 days ago
Another example of how IgAN is not a benign disease. Middle age pt with CKD, hematuria, proteinuria. Strong mesangial IgA staining and deposits by EM. Unfortunately extensive IFTA at diagnosis. Can we catch these pts earlier?
#renalpath
#athsky
#nephsky
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reposted by
Grace Choung, MD 박영이
Swapnil Hiremath 🍁🇨🇦
16 days ago
interesting post hoc analysis from TESTING trying to identify which patients might benefit from steroids in IgAN (esp useful for markets where thats all we have!)
www.kidney-international.org/article/S008...
in
@kidneyint.bsky.social
#NephSky
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A secondary analysis of the TESTING trial predicted individual patient response to corticosteroid treatment in IgA nephropathy
Corticosteroids are effective for treating IgA nephropathy but have important adverse effects. In this secondary analysis of the TESTING cohort, we generated a model to predicts, for an individual pat...
https://www.kidney-international.org/article/S0085-2538(26)00005-0/abstract?rss=yes
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reposted by
Grace Choung, MD 박영이
Jonathan Zuckerman MD PhD
16 days ago
Dual AL/AH amyloidosis in a pt with plasma cell dyscrasia. Mass spec was confirmatory.
#renalpath
#pathsky
#nephsky
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Genotype-phenotype characteristics and disease progression of FAN1-related karyomegalic tubulointerstitial nephropathy - Kidney International
www.kidney-international.org/article/S008...
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Genotype-phenotype characteristics and disease progression of FAN1-related karyomegalic tubulointerstitial nephropathy
Biallelic variants in Fanconi Anemia-associated Nuclease 1 (FAN1) cause karyomegalic tubulointerstitial nephropathy (KIN), a condition poorly characterized in terms of kidney survival, patient surviva...
https://www.kidney-international.org/article/S0085-2538%2826%2900007-4/fulltext
16 days ago
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Collagenofibrotic Glomerulopathy Associated With Homozygous STAB2 and Heterozygous STAB1 Variants: A Case Report - American Journal of Kidney Diseases
www.ajkd.org/article/S027...
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Collagenofibrotic Glomerulopathy Associated With Homozygous STAB2 and Heterozygous STAB1 Variants: A Case Report
This case report investigates the genetic basis of collagenofibrotic glomerulopathy (CG), a type of collagen type III glomerulopathy. It is a rare kidney disease characterized by collagen III depositi...
https://www.ajkd.org/article/S0272-6386%2826%2900006-5/fulltext
19 days ago
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reposted by
Grace Choung, MD 박영이
Jonathan Zuckerman MD PhD
20 days ago
Well formed non-necrotizing granulomas in a pt with worsening renal function and sarcoidosis. Some granulomas in peri-vascular locations without vasculitis.
#renalpath
#pathsky
#nephsky
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reposted by
Grace Choung, MD 박영이
20 days ago
Nonprogressive #Nephrotic Range #Proteinuria Because of Indirect #Cubilin Dysfunction
https://doi.org/10.1016/j.ekir.2025.09.046
#Nephrotic
#Proteinuria
#Cubilin
#KIRNephrologyRounds
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reposted by
Grace Choung, MD 박영이
IPNA Pediatric Nephrology
20 days ago
APOL1 high-risk variants predispose to CKD in people of African genetic ancestry due to podocyte toxicity; CAKUT have variable outcomes potentially driven by podocyte injury. Read this Original Article on APOL1 kidney risk variants & outcomes in children w/CAKUT.
link.springer.com/article/10.1...
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Protocadherin FAT1-associated membranous nephropathy after hematopoietic stem cell transplantation – a cohort study with clinico-pathological correlations url:
academic.oup.com/ckj/article/...
#nephsky
#pathsky
#renalpath
#nephrology
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Protocadherin FAT1-associated membranous nephropathy after hematopoietic stem cell transplantation – a cohort study with clinico-pathological correlations
AbstractBackground. The identification of causative antigens for membranous nephropathy (MN) has revolutionized the comprehension of the pathophysiology of
https://academic.oup.com/ckj/article/doi/10.1093/ckj/sfag005/8419680
20 days ago
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reposted by
Grace Choung, MD 박영이
22 days ago
Spectrum of Kidney #Biopsy Findings in a Patient With Primary #Myelofibrosis
https://doi.org/10.1016/j.ekir.2025.10.010
#Biopsy
#Myelofibrosis
#KIRNephrologyRounds
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reposted by
Grace Choung, MD 박영이
Jonathan Zuckerman MD PhD
21 days ago
Some smudgy mesangial IgG staining indicating a surprise fibrillary GN superimposed on advanced diabetic nephropathy. EM was confirmatory (~14 nm fibrils in some mesangial areas) as was the DNAJB9 stain. Value of biopsy in diabetic pts.
#renalpath
#nephsky
#pathsky
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reposted by
Grace Choung, MD 박영이
American Journal of Kidney Diseases
23 days ago
IgG3κ Monoclonal Membranous Nephropathy Associated With Acquired Lecithin Cholesterol Acyltransferase Deficiency
bit.ly/3Le1OFK
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reposted by
Grace Choung, MD 박영이
Swapnil Hiremath 🍁🇨🇦
23 days ago
We will be discussing C3G today - so review the disease and the journey so far with Prof Carla Nester:
youtu.be/Fo6J__RgWA0?...
From our
#NephGR
a few months ago Excellent crisp overview of the science!
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C3 Glomerulopathy: The Promise of a targeted therapy with Prof. Carla Nester
YouTube video by Ottawa Nephrology
https://youtu.be/Fo6J__RgWA0?si=vodN8AaC9MpYeknZ
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reposted by
Grace Choung, MD 박영이
Swapnil Hiremath 🍁🇨🇦
23 days ago
excellent review of complement based therapies in ...IgA Nephropathy in
@ajkd.bsky.social
from
@sstoneman.bsky.social
et al
www.ajkd.org/article/S027...
Fig 1 with the 4-hit theory 1/
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Evaluating Chronicity Scores for Outcomes in Lupus Nephritis Patients - Kidney International Reports
www.kireports.org/article/S246...
#pathsky
#nephsky
#nephrology
#renalpath
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Evaluating Chronicity Scores for Outcomes in Lupus Nephritis Patients
To evaluate the prognostic value of the Mayo Clinic Chronicity Score (MCCS) compared with the National Institutes of Health Chronicity Index (NIH-CI) in lupus nephritis (LN).
https://www.kireports.org/article/S2468-0249%2826%2900009-4/fulltext
23 days ago
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Kidney Outcomes in ANCA-Glomerulonephritis According to Induction Immunosuppression and Histopathology - Kidney International Reports
www.kireports.org/article/S246...
#pathsky
#nephsky
#nephrology
#renalpath
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Kidney Outcomes in ANCA-Glomerulonephritis According to Induction Immunosuppression and Histopathology
Cyclophosphamide (CYC) and rituximab (RTX), alone or combined, are the mainstays of induction therapy in ANCA-glomerulonephritis. It is unknown whether the response to induction is differentially affe...
https://www.kireports.org/article/S2468-0249%2826%2900007-0/fulltext
23 days ago
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reposted by
Grace Choung, MD 박영이
Edgar V. Lerma 🇵🇭
about 1 month ago
Kidney Biopsy 🔬 101 from
@changucanspare.bsky.social
#Nephpearls
#NephSky
👉
shop.lww.com/Handbook-of-...
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The Pathology of IgA Nephropathy: How Can It Inform Management
www.seminarsinnephrology.org/article/S027...
#renalpath
#pathsky
#nephrology
#nephsky
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The Pathology of IgA Nephropathy: How Can It Inform Management?
IgA nephropathy (IgAN), the world's most common form of primary glomerulonephritis (GN), has a variable clinical and pathologic presentation. While all cases of IgAN show dominant or codominant glomer...
https://www.seminarsinnephrology.org/article/S0270-9295(25)00005-1/abstract
25 days ago
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reposted by
Grace Choung, MD 박영이
JCI insight
26 days ago
The native human glomerulus features a slit diaphragm resembling a densely interwoven fishnet Here, Achilleas S. Frangakis & team resolve a specialized component of the kidney’s filtration barrier across the extracellular space at the nanometer scale:
doi.org/10.1172/jci....
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Grace Choung, MD 박영이
Sayna Norouzi, MD
26 days ago
Genetic testing is transforming how we practice nephrology. Check out our recent article in KidneyNews.
#Nephrology
#Genetics
#KidneyDisease
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reposted by
Grace Choung, MD 박영이
American Journal of Kidney Diseases
25 days ago
#renalpath
Fibrillary glomerulonephritis with cellular crescent (Jones silver stain)
bit.ly/4jyP0qJ
(FREE)
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reposted by
Grace Choung, MD 박영이
American Journal of Kidney Diseases
27 days ago
What's New in Membranous Nephropathy and How to Incorporate New Antigen Discoveries into Clinical Practice? REVIEW by Ladan Zand, Fernando C. Fervenza, and Sanjeev Sethi
bit.ly/3J9d1qO
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reposted by
Grace Choung, MD 박영이
Renal Pathology Society (RPS)
30 days ago
If you are registered to 6thIRPC online, we have news for you. All online participants will have the opportunity to submit their abstracts (research or interesting cases), deadline is January 15, 2026. Info below 👇 Behalf of RPS & SLANH organizing Committee
#renalpath
#pathsky
#nephsky
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