A startling biopsy. Severe acute TMA in a pt with suspected scleroderma renal crisis. Massive vascular thrombosis, mucoid intimal edema, and early onion skin change associated with severe cortical necrosis. #renalpath #nephsky #pathsky

Renal hypodysplasia (RHD) is a common & severe form of congenital anomalies of the kidney and urinary tract, often leading to CKD in children. Read this Original Article on characteristics of RHD in children: insights from a 10-yr single-center cohort. link.springer.com/article/10.1...

Core Curriculum by Kristen Tillquist et al. The Nephrologist’s Perspective in Evaluation and Management of Localized Renal Masses bit.ly/4o6z0NG #OpenAccess

📣 Only two weeks left to submit your WCN’26 abstract! Don’t miss the chance to: 🌍 gain recognition at the 2026 global kidney care event 🏆 win one of 3 prestigious awards 📰 get your work published in KIReports® congress supplement Submit by October 22➡️http://lite.spr.ly/6...

Revisiting proliferative glomerulonephritis with monoclonal immunoglobulin deposits through immunoglobulin repertoire sequencing doi.org/10.1016/j.kint.2025.07.039 #NephSky #MedSky #kidneypath #renalsky @mayoclinic.org

#RenalPath: AJKD Atlas of Renal Pathology: Diffuse Mesangial Sclerosis bit.ly/46AK5kj (FREE)

Kidney txp biopsy for AKI (~6 post txp). Tubular injury associated with granular and ropey trichome positive casts. IHC confirmed myoglobin cast nephropathy. CK found to be very high; thought to be due to statin related myopathy. #renalpath #pathsky #nephsky

Bx for new onset NS in an older adult. Serologic work up including SPEP/UPEP IFE negative. Bx shows membranous pattern with few double contours. IgG3-k restriction and mottle EM deposits c/w PGNMID with membranous predominant pattern. PLA2R- #renalpath #pathsky #nephsky

Monitor anti-PLA2r titers every three moths during treatment. #GlomCon

APOL1 prevalence in CKD in Brazil www.kireports.org/article/S246... In hindsight should not be a surprise! @kireports.bsky.social

🌍 Apply for ISN Committees & Working Groups! Make an impact on global kidney care. You can express an interest yourself or nominate a colleague. ⏳ Deadline: Oct 22, 2025, 5 p.m. CEST 👉 http://lite.spr.ly/6... #ThisIsISN #ISNWCN

Proposals to Make Diagnostic Criteria truly Usable and Useful to Pathologists Worldwide jcp.bmj.com/content/earl... #Pathology @smlungpathguy.bsky.social @who.int @uscap.org @pathologists.bsky.social @americancancersoc.bsky.social @pathoverseas.bsky.social @ampath.bsky.social

Case Report: Exostosin 1-associated membranous nephropathy and Guillain-Barré syndrome: a common autoimmune etiology? #nephsky www.frontiersin.org/journals/nep...

Critical role of transcription factor SOX4 in tubular epithelial cell dedifferentiation and fibroblast activation during kidney fibrosis #openaccess

Kidney injury and colocalization of complement C3, IgA, and IgG in glomerular immune-complex deposits of patients with IgA nephropathy or IgA vasculitis with nephritis. #openaccess

Bartonella is back! In kidney transplant recipients….from donors! www.kireports.org/article/S246... in @kireports.bsky.social

Adequacy and safety of pediatric native kidney biopsy using 16- and 18-gauge needles

It's the weekend-before-abstracts-are-due and we need you to remember two very important things: 1. You've got this 2. Music might help: open.spotify.com/playlist/5EI... #PathSky #USCAP2026 #YouGotThis

New from Dr Barisoni and colleagues in Kidney International Clinical relevance of computationally derived tubular features and their spatial relationships with the interstitial microenvironment in minimal change disease/focal segmental glomerulosclerosis pubmed.ncbi.nlm.nih....

New Podcast: Drs. Levin and Wernerson discuss the findings from their study, "Transcriptomic Patterns in Adult and Pediatric Patients with IgA Nephropathy or IgA Vasculitis with Nephropathy." Listen here: kidney.pub/JPOD0787 #ASNJASN

Now showing Sibeprenlimab VISIONARY Phase 3 trial. Presentation originally give at ERA #GlomCon

First session will be on C3 Glomerulopathy First up Jean Hou on the pathology of C3G The pathyology if C3G depends on IF #GlomCon

Barratt then presented phase 2 data on atrasentan in IGAN on subgroups. This was an open label basket trial that looked at a number of diseases, but this is only data from IGAN. Outcome was proteinuria at 12 weeks #GlomCon

Next up Zigakibart in IgAN treated for 76 weeks. Zigakibart is an April inhibitor (learned how to access the poster slides, so screen grabs rather than photos of the slides) Title, methods, and table 1 demographics #GlomCon

📖 This weekend don't miss our @kireports.bsky.social #ISNFridaySelection: Efficacy of Acthar gel and Tacrolimus in DNA-JB9 Positive Fibrillary Glomerulopathy www.kireports.org/ar...

Glassock starts with "my mother told me if you have nothing nice to say, keep your moouth shut" He is going to violate those instructions. #GlomCon #KDIGO

For this #FluorescenceFriday, a gorgeous image of an adult mouse kidney labeled with AQP2 and alpha SMA antibodies. AQP2 (green) marks the collecting duct and distal connecting segment while SMA marks the arterial tree. Courtesy of talented postdoc Sarah McLarnon.

MIRAGE syndrome is a rare multisystem disorder caused by gain-on-function SAMD9 variants. Read these Clinical Insights into a 1-yr-old boy w/MIRAGE syndrome & nephrotic syndrome, whose kidney histopathology revealed membranous nephropathy. link.springer.com/article/10.1...

And it’s live Iptacopan in C3GN makes it to @thelancet.com www.thelancet.com/journals/lan... #NephSky

#RenalPath: Minimal change disease (MCD) is the most common cause of nephrotic syndrome in children aged 1 to 7 yrs. This figure shows preserved cortex with normal-appearing glomerulus. In this case, the tubules are distended with loss of brush border bit.ly/3W0go60 (FREE)

Executive summary of the #KDIGO 2025 Clinical Practice Guideline for the Management of Immunoglobulin A Nephropathy ( #IgAN) and Immunoglobulin A Vasculitis ( #IgAV) doi.org/10.1016/j.kint.2025.04.003 #OpenAccess #MedSky #NephSky #glomerulardisease @imperialcollegeldn.bsky.social

Kidney injury and colocalization of complement C3, IgA, and IgG in glomerular immune-complex deposits of patients with #IgAnephropathy or #IgAvasculitis with nephritis. doi.org/10.1016/j.kint.2025.07.038 #MedSky #NephSky #OpenAcess #IgAN #glomerulardisease

Discussing evidence for autoantibodies against nephrin as cause of diffuse podocytopathy. Points out that toxins and drug induced podocytopathy (bisphosphonates) do not have anti-nephrin antibodies and do not respond to immunosuppression #GlomCon

Opinion-based approach to genetic 🧬 testing in adult-onset FSGS #GlomConHawaii 🌊 #Nephpearls #NephSky 📌 Note that viral- and drug-associated forms of FSGS are usually excluded by clinical and serologic evaluation 👉 pubmed.ncbi.nlm.nih.gov/29321142/

Revisiting proliferative glomerulonephritis with monoclonal immunoglobulin deposits through immunoglobulin repertoire sequencing #nephsky www.kidney-international.org/article/S008...

Excellent thread below I will also plug this talk by Paola Romagnani on podocytopathies youtu.be/bRMeqaGgA9I?... #GlomCon #NephGR

On to Membranous at #GlomCon Sanjeev Sethi king of membranous antigens to lead off after a hilarious introduction by Seethapathy #GlomCon

Next up Podocytopathies with ASstrid Weins who calls out that she is wearing a geography appropriate flowered dress #GlomCon

Next up is Joseph Gaut to talk about the pathology of Lupus Nephritis. The pathology classification of 1 through 6 has been maturing over time. Still does not include vascular lesions.

Had some wifi trouble during the lupus session. It was spirited. We are back with paraprotein mediated kidney disease Starting off with pathology, Dr Venesa Bijol from Arkana #GlomCon

Join RPS-GlomCon for Renal Pathology Webinar Series Sunday, September 28, 2025 8:00 AM - 9:00 AM Pacific Time Ingeborg Bajema, MD, PhD To register👉https://renalpathsoc.org/event-6113937 #renalpath #pathsky #nephsky #nephrology @glomcon.org

Heavy Chains, Heavy Consequences: A Case of Concomitant Heavy Chain Amyloidosis and Heavy Chain Deposition Disease. Fibrils and powdery deposits. #renalpath #nephsky #pathsky www.sciencedirect.com/science/arti...

Join RPS-GlomCon for Renal Pathology Webinar Series Sunday, September 28, 2025 8:00 AM - 9:00 AM Pacific Time Ingeborg Bajema, MD, PhD To register👉https://renalpathsoc.org/event-6113937 #renalpath #pathsky #nephsky #nephrology @glomcon.org

#RenalPath: Diffuse mesangial sclerosis with typical-appearing dense collagenous material within the mesangium (Masson trichrome stain). bit.ly/2Hg0Ym1 (FREE)

Review by Michelle A. Baum, Mallory Mandel, and Michael J.G. Somers: Understanding Rare Kidney Stone Diseases: A Review bit.ly/3I2RiA6 (FREE)

Perspective by Roberto F. Nicosia and Paolo Cassoli: Malpighi’s Forgotten Drawings of Renal Glomeruli bit.ly/4lWCWyY

ICYMI: New content online: Mechanisms of diabetic kidney disease and established and emerging treatments

Case report: De novo C3 Glomerulonephritis in a Kidney Transplant Recipient Associated with an Unreported CFH Variant #openaccess #C3GN

Multiple diagnoses not uncommon in kidney biopsies. This case showed nodular diabetic nephropathy, a mostly chronic ANCA associated GN, and to top it off some interstitial ALECT2 amyloidosis. #renalpath #nephsky #pathsky

Wide variety of morphologies in this case of crystalline light chain proximal tubulopathy: mottle lysosomes, crystals, and fibrils. #renalpath #nephsky #pathsky