Melvin Chan
@mchanmd.bsky.social
📤 659
📥 855
📝 103
Current NSMC Faculty, CU Ped Neph, and IM faculty; interested in CKM and transition of care
pinned post!
📌
over 1 year ago
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Can’t wait for this discussion. Already have a few patients on it and have been going well!
#NephJC
add a skeleton here at some point
about 1 month ago
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New phase 3 data from the ATTAIN-MAINTAIN trial.
#NephSky
#Obesity
#GLP1
lilly.mediaroom.com/2025-12-18-L...
about 2 months ago
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The future of nephrology
add a skeleton here at some point
about 2 months ago
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reposted by
Melvin Chan
Sarah Sanghavi
2 months ago
Appreciate this excellent work showing GLP-1 agonists reduce mortality in patients on dialysis and improve their chances of receiving a transplant. Hopefully, it will help me get them approved for my patients through the VA.
#nephsky
journals.lww.com/cjasn/pages/...
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reposted by
Melvin Chan
Michelle Rheault, MD
2 months ago
Congenital and infantile nephrotic syndrome: genotype-phenotype associations
pubmed.ncbi.nlm.nih.gov/41339767/
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Thrilled to have our review article on complement-mediated biomarkers published
#NephSky
journals.lww.com/cjasn/abstra...
2 months ago
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Excited to match two amazing nephrology fellows for next year!
@childrenscolo.bsky.social
2 months ago
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More evidence showing that GLP1s may be modulate rheumatic disease
#MedSky
#NephSky
:
rheumatology.org/press-releas...
and
pubmed.ncbi.nlm.nih.gov/40994310/
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Glucagon-Like Peptide-1 Receptor Agonist Use and the Risk of Adverse Cardiac and Kidney Outcomes Among Patients with Systemic Lupus Erythematosus and Lupus Nephritis - PubMed
We found lower risks of adverse CV and kidney outcomes and mortality with GLP-1RA use compared with DPP4i use among patients with lupus and T2D.
https://pubmed.ncbi.nlm.nih.gov/40994310/
3 months ago
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More tools for our advanced CKD patients!
add a skeleton here at some point
3 months ago
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reposted by
Melvin Chan
Michelle Rheault, MD
3 months ago
Late breakers that included children: ✅Setanaxib in Alport (12+) Late breakers that did NOT include children: 🚫Atacicept in IgAN 🚫CONFIDENCE 🚫PISCES: Fish oil in Dialysis 🚫LIBERATE-D 🚫balcinrenone + dapa 🚫Obintuzumab in lupus nephritis 🚫Sibeprenlimab in IgA 🚫MIL62 in membranous +more
#KidneyWk
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reposted by
Melvin Chan
Nephrology Journal Club
4 months ago
🎨Beautiful visual abstract by Dr Natalia Nombera @roxnonna23.bsky.social #NephJC
www.nephjc.com/news/...
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Great read on ways of measuring renal function. Shout out to
@elbaonelida.bsky.social
www.kireportscommunity.org/post/towards...
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Towards new ways of assessing kidney function. Where to look to improve?
Written by Elba MedinaReviewed by Brian Rifkin;Sophia AmbrusoToday, current methods for measuring kidney function, due to several critical limitations, need to be reimagined. In the reimagining Kidney...
https://www.kireportscommunity.org/post/towards-new-ways-of-assessing-kidney-function-where-to-look-to-improve
4 months ago
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A great read on the history and upcoming anticoagulation targets especially for our dialysis patients!
#NephSky
www.kireportscommunity.org/post/bleedin...
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Bleeding, Clotting, and Kidney Disease in Atrial Fibrillation: Can Factor XI Inhibitors Change the Game?
Explore how we are uncoupling hemostasis and thrombosis via Factor XI inhibitors and how it is may change anticoagulation for atrial fibrillation in kidney disease
https://www.kireportscommunity.org/post/bleeding-clotting-and-kidney-disease-in-atrial-fibrillation-can-factor-xi-inhibitors-change-the-g
5 months ago
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Looks like tirzepatide have benefits for those with T1DM, with insulin needs reduced within 2 weeks of treatment.
#NephSky
#MedSky
www.medscape.com/viewarticle/...
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First Randomized Trial of Tirzepatide in T1D Shows Benefits
Tirzepatide reduced weight, A1c, and insulin dose in type 1 diabetes in a small randomized controlled trial.
https://www.medscape.com/viewarticle/first-randomized-trial-tirzepatide-t1d-shows-benefits-2025a1000poc
5 months ago
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reposted by
Melvin Chan
Nephrology Journal Club
5 months ago
Change is in the Autumn air 🌬️🍂 Join use only on
#Bluesky
on 9/16/25 at 9pm EST. We're discussing the 2025 ACC/AHA Hypertension Guideline Update. 🫀🫘🧠
#NephSky
#MedSky
www.nephjc.com/news/accaha2025-klno3
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PREVENT, Detect, Treat: What’s New in the 2025 Hypertension Toolkit — NephJC
This week, we will discuss the AHA/ACC 2025 hypertension guideline update. Wow, have eight years flown by?
https://www.nephjc.com/news/accaha2025-klno3
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There’s continued growing evidence that childhood onset hypertension leads to worse outcomes.
add a skeleton here at some point
5 months ago
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Thoughts about Wegovy vs Zepbound for MACE Reduction?
#MedSky
#NephSky
Finding: -Semaglutide showed 29% reduction in MACE Limits: -Small # of events -Retrospective Implications: -Wegovy may be better for those with ASCVD -Does GIP have any CV benefits?
sciencehub.novonordisk.com/content/dam/...
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https://sciencehub.novonordisk.com/content/dam/sciencehub/global/en/congresses-and-scientific-publications/congresses/esc2025/wilson/documents/ESC_2025_STEER_Presentation_LUM-KOP-01222_FINAL.pdf
5 months ago
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reposted by
Melvin Chan
Brian Rifkin
5 months ago
Check out the latest
@kireports.bsky.social
community blog from
@husamjz.bsky.social
Anticoagulantion in ESRD patients with atrial fibrillation:
www.kireportscommunity.org/post/bleeding-clotting-and-kidney-disease-in-atrial-fibrillation-can-factor-xi-inhibitors-change-the-g
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Bleeding, Clotting, and Kidney Disease in Atrial Fibrillation: Can Factor XI Inhibitors Change the Game?
By. Husam Alzayer, MD, MSc, MRCPIReviewed by Sophia Ambruso, DOIntroduction Bleeding and thrombosis represent one of the many paradoxes faced by patients with kidney disease. As kidney function declin...
https://www.kireportscommunity.org/post/bleeding-clotting-and-kidney-disease-in-atrial-fibrillation-can-factor-xi-inhibitors-change-the-g
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reposted by
Melvin Chan
Nephrology Journal Club
5 months ago
🤔 How often is end-stage kidney disease in patients with MCD/ FSGS?
#NephSky
#MedSky
@brianrifkin.bsky.social
dissected the conclusions from the RaDar study in this
#NephJCshorts
*the original article from
@asnpublications.bsky.social
www.nephjc.com/news/nephjc-...
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NephJC Shorts: MCD and FSGS Outcomes — NephJC
A NephJC Shorts discussion of the long term data on kidney failure in FSGS and MCD
https://www.nephjc.com/news/nephjc-shorts-mcd-fsgs
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reposted by
Melvin Chan
Nephrology Journal Club
6 months ago
Check out the ACHIEVE visual abstract by
@nephromommy-akshu.bsky.social
www.nephjc.com/news/2025/8/...
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The ACHIEVE visual abstract — NephJC
the use of spironolactone in patients on dialysis did not alter mortality or hospitalizations for heart failure. Similar results were seen in the simultaneously released ALCHEMY trial.
http://www.nephjc.com/news/2025/8/the-achieve-trial-visual-abstract-jjaw5
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reposted by
Melvin Chan
6 months ago
Please share this
#Skytorial
with your followers and friends! Don't forget to check out KI Reports Community for more:
kireportscommunity.org
. Thanks to
@sophia-kidney.bsky.social
,
@brianrifkin.bsky.social
, and
@mchanmd.bsky.social
for great feedback!
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Bought a construction truck food mat for my 4.5 year old. Instead of letting the food particles stay there he pushes it to the floor to keep the mat clean. “ChildPerspectives
9 months ago
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For all my little beans out there, don’t forget to read the latest recommendations on IgAN and IgAVN by
@mdabdulqader83.bsky.social
on
@kireports.bsky.social
www.kireportscommunity.org/post/navigat...
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Navigating the Challenges of IgA Nephropathy and IgA Vasculitis Nephritis in Children
Written by: Henny Adriani PuspitasariIntroduction:IgA nephropathy (IgAN) and IgA vasculitis nephritis (IgAVN) are kidney diseases that can significantly impact children's health. While they share some...
https://www.kireportscommunity.org/post/navigating-the-challenges-of-iga-nephropathy-and-iga-vasculitis-nephritis-in-children
10 months ago
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reposted by
Melvin Chan
10 months ago
💥Hey
#NephSky
! Welcome to a 🆕
#tweetorial
#xtorial
brought to you by @KIReports @ISNkidneycare
#Skytorial
. Our author is
@elbaonelida.bsky.social
nephrologist at Hospital General de Mexico @hgm_nefrologia. Please also check out
www.kireportscommunity.org
educational
#blogposts
. FOLLOW US!🫰
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reposted by
Melvin Chan
11 months ago
🚨Hey
#NephSky
! Welcome to a new
#Medsky
#Skytorial
brought to you by
@kireports.bsky.social
Our author is
@brianrifkin.bsky.social
nephrologist in Hattiesburg, MS Please check out
#KIReportsCommunity
educational
#blogposts
too!
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reposted by
Melvin Chan
Nephrology Journal Club
11 months ago
⏰2 hours to chat It’s #NephJC time! Tonight we dive into something BIG —literally & figuratively: the first-ever
@kdigo.org
#NephJC
2025 ADPKD guidelines 🧬 Finally, this disease gets its own spotlight.
#NephJC
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KDIGO 2025 Clinical Practice Guideline for the Evaluation, Management, and Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD) - PubMed
KDIGO 2025 Clinical Practice Guideline for the Evaluation, Management, and Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)
https://pubmed.ncbi.nlm.nih.gov/39848759/
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What is the evidence of SGLT in cystic kidney disease?
#askrenal
@kireports.bsky.social
11 months ago
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reposted by
Melvin Chan
DivyaveerSS
11 months ago
🆕 🥇FDA approved therapy for C3 Glomerulopathy Iptacopan : inhibitor of the alternative complement pathway by specifically binding to and inhibiting factor B
#Hope
for
#kidney
#disease
#Great
time to be in
#Nephrology
#Nephsky
#Nephbluesky
#Medsky
#Medbluesky
#Nephronuggets
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It is March. Do you know what that means?
#NephMadness
@nephmadness.bsky.social
! Today let's chat about obesity in transplant donors and recipients! Here is a link to the blog:
ajkdblog.org/2025/03/01/n...
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#NephMadness 2025: Obesity in Kidney Transplant Region
Submit your picks! | @NephMadness | @nephmadness.bsky.social | NephMadness 2025 Selection Committee Member: Swee-Ling Levea @SweeLevea Swee-Ling Levea is an Associate Professor of Medicine at Unive…
https://ajkdblog.org/2025/03/01/nephmadness-2025-obesity-in-kidney-transplant-region/
12 months ago
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reposted by
Melvin Chan
Dr Pallavi Prasad, MD, DNB ( Nephrology)
about 1 year ago
COI; I have never EVER done these tests .anyone using these in their practice?
#NephJC
@kidneyboy.bsky.social
?
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reposted by
Melvin Chan
Nephrology Journal Club
about 1 year ago
Think primary aldosteronism means hypertension, hypokalemia and metabolic alkalosis...think again. Can undercover hyperaldosteronism be a key to CKD?🔎
#NephJC
chat 2/11/25 at 9pm EST
#NephSky
www.nephjc.com/news/primary...
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Undercover Aldosterone — NephJC
This week, we will discuss the origins of primary hyperaldosteronism in normotensive patients. Could this undetected anomaly be the cause of idiopathic hypertension and CKD?
https://www.nephjc.com/news/primaryhyperaldosteronism-hypertension-ego45
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reposted by
Melvin Chan
Brian Rifkin
about 1 year ago
But what if…primary hyperaldosteronism is more common then we thought, even in normotensive people without CKD, and the root cause of a significant number of “hypertensive nephrosclerosis” patients? (Sneak peak at our next
#NephJC
for 2/11/25)
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Great work! 👏
add a skeleton here at some point
about 1 year ago
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reposted by
Melvin Chan
about 1 year ago
🚨Skeetorial Alert🚨 1/ Hey
#NephTwitter
! Welcome to a 🆕
#skeetorial
brought to you by
@kireports.bsky.social
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See our blog/skeetorial highlighting
@kireports.bsky.social
presentation at the World Congress of Nephrology 2025!
add a skeleton here at some point
about 1 year ago
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reposted by
Melvin Chan
National Kidney Foundation
about 1 year ago
BREAKING NEWS: The FDA has approved Ozempic for patients with chronic kidney disease. This means the popular injection can be used to reduce the risk of kidney disease worsening, kidney failure and death from cardiovascular disease in patients with chronic kidney disease and diabetes.
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FDA approves Novo Nordisk's Ozempic to treat chronic kidney disease in those with diabetes, expanding its use
Expanded Ozempic approval in the U.S. could transform how doctors treat patients with chronic kidney disease, which involves a gradual loss of kidney function.
https://www.cnbc.com/2025/01/28/novo-nordisks-ozempic-wins-fda-approval-for-chronic-kidney-disease.html
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reposted by
Melvin Chan
Nayan Arora
about 1 year ago
In pts w/ HF w/out DM what's the risk:benefit of holding SGLT2i (recommended) before a procedure vs not? There is harm in holding flozins for 30 days and the risk of EDKA is low. Main risk being - once held they don't get resumed quickly
#cardiosky
#nephsky
www.ahajournals.org/doi/10.1161/...
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Blinded Withdrawal of Long-Term Randomized Treatment With Empagliflozin or Placebo in Patients With Heart Failure | Circulation
BACKGROUND: It is not known whether the benefits of sodium-glucose cotransporter 2 inhibitors in heart failure persist after years of therapy. METHODS: In the EMPEROR-Reduced (Empagliflozin Outcome ...
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.065748
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Really impresses me at how far anti-obesity medications have come along. Found this recent paper on a new phase 1 trial on a GLP1/GIPR medication. Results are still very preliminary but exciting in the world of
#CKM
short 🧵
www.nature.com/articles/s42...
about 1 year ago
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reposted by
Melvin Chan
about 1 year ago
🌠Skeetorial Alert 🌠 1/ Hey
#NephSky
! Welcome to a 🆕
#skeetorial
brought to you by
@kireports.bsky.social
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reposted by
Melvin Chan
about 1 year ago
1/ Hello,
#NephSky
! Excited to share a 🆕
#Skeetorial
on Automated Peritoneal Dialysis (APD) as a modality for Urgent Start Dialysis! Brought to you by the fantastic team at
@kireports.bsky.social
Let's dive in!
#skeetorial
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reposted by
Melvin Chan
about 1 year ago
1/ Hey
#NephSky
! Welcome to a 🆕
#skeetorial
brought to you by @KIReports. Want more, check out the blog here:
www.kireportscommunity.org/post/type-1-...
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Type 1 Diabetes: Two Roads Diverged, How Far Have We Come?
Author: Brian Rifkin, MDHattiesburg ClinicHattiesburg, MSCare of patients with diabetes has advanced significantly since Banting and Best discovered insulin over a century ago. The prognosis of type 1...
https://www.kireportscommunity.org/post/type-1-diabetes-two-roads-diverged-how-far-have-we-come-in-kidney-outcomes
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reposted by
Melvin Chan
Prof Claire Hills
about 1 year ago
GLP-1 Receptor Agonist and SGLT2 Inhibitor Prescribing in People With Type 1 Diabetes 👇👇👩🔬🥼🧪
#diabetes
#CardioSky
#NephSky
#MedSky
#Kidneydisease
#cardiorenal
#cardiovascular
jamanetwork.com/journals/jam...
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GLP-1RA and SGLT2 Inhibitor Prescribing in People With Diabetes
This pooled cross-sectional study explores prescribing rates for glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter 2 inhibitors among US patients with type 1 diabetes.
https://jamanetwork.com/journals/jama/article-abstract/2825312?s=09
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reposted by
Melvin Chan
Jade Teakell, MD
about 1 year ago
Join us for
#NephJC
chat in ~30 minutes! First time on
@bsky.app
!! 🤩 Summary 👉
www.nephjc.com/news/potassi...
#NephSky
add a skeleton here at some point
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What are your practice patterns with SGLT2 inhibitors? Do you tend to stop it if a patient has a decrease in eGFR or AKI?
@asnkidney.bsky.social
journals.lww.com/cjasn/fullte...
about 1 year ago
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reposted by
Melvin Chan
Cristina Popa
over 1 year ago
Sometimes, when on call, I get consults for labs signaling a lower-than-normal creatinine.... If 2 am when this happens, I tend to be dismissive However, here is a nice overview of ⬇️ creatinine causes
#NephSky
#MedSky
🔗
karger.com/bpu/article/...
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reposted by
Melvin Chan
Swapnil Hiremath 🍁🇨🇦
over 1 year ago
A list of
#NephTwitter
#NephJC
followers and supporters Small list but will be growing!
bsky.app/profile/did:...
add a skeleton here at some point
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reposted by
Melvin Chan
over 1 year ago
🧑🎓Skytorial Alert 🧑🎓 1/ Hey
#NephSky
! Welcome to a 🆕
#BlueSky
#Skytorial
brought to you by
@kireports.bsky.social
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