as far as I know the fish oil craze started with bad math over an Icelandic or Greenland study, and has been a cesspit of bad science since then and this finding reminds me of what my mom said: if it is to good to be true, it is

Agreed - already have some proactive DMI folks on Finerenone - has been safe and lowers proteinuria in my hands

We are 2 for 2 with positive trials so far. LIBERATE-D shows benefit with a conservative vs conventional dialysis strategy in AKI-D. The difference in mortality is concerning though? Simultaneous pub 👇🏾 #kidneywk jamanetwork.com/journals/jam...

Shocking first high impact trial of the day. Fish oil reduces CV events in dialysis patients! #Pisces #kidneywk Simultaneous pub in NEJM www.nejm.org/doi/full/10....

For finerenone in type 1 DKD I think albuminuria is OK For Atacicept - this is preliminary data which gets them accelerated FDA approval and a few months of making 💰until the GFR slope analysis comes through? #KidneyWk

While I agree, here in Australia the drugs will not get funded by the govt without the harder endpoints unless of course the price is okay which of course is not going to happen. It’s exciting to see all these new therapeutics but unless the cost comes down I doubt we will see them in Australia soon

@sophia-kidney.bsky.social is working really hard at this conference #kidneywk

Midodrine and octreotide should not be first line therapy for HRS-AKI #kidneywk

@sophia-kidney.bsky.social got shoved into a corner by ASN but well worth the trek to check out her poster and try out abcKidney #kidneywk

Small trial of lysine chloride in euvolemic patients with heart failure. Median furosemide dose was 80mg. Chloride supplementation reduced plasma volume and improved diuretic response. Interesting but maybe not the population I would use it in? #kidneywk

#kidneywk has puppies!

We have a new therapy for type 1 diabetes! FINE-ONE with significant proteinuria reduction compared to placebo on a background of RASi with an acceptable safety profile. Where’s the simultaneous pub?? Sglt2 inhibitors are next…#kidneywk

Interim analysis of atacicept (dual BAFF/APRIL inhibitor) shows successful proteinuria reduction vs placebo. Also reduced Gd-IgA1 levels. Adding to the IgA armamentarium. Simultaneous pub 👇🏾 #kidneywk www.nejm.org/doi/full/10....

New episode of Freely Filtered with @brendonneuen.bsky.social @hswapnil.medsky.social @captainchloride.bsky.social @sophia-kidney.bsky.social and author Muth Vaduganathan discussing the CONVINCE trial www.nephjc.com/freelyfilter... With chapters, refs, and pictures

Going to add this to my lecture slides.

Interesting diuretic resistance study. Adunctive thiazides take the lead over loop intensification? Nice discussion on mechanisms of DR, both practical and hypothetical. #nephsky journals.lww.com/jasn/abstrac...

🤔 I happen to know @jordybc.bsky.social is a scotch aficionado www.cnn.com/2025/08/14/h...

Latest episode of @freelyfiltered.bsky.social is live! This one on the two RCTs of DDAVP to prevent renal biopsy bleeding. We had special guest Vandana Niyyar join us. @medpeedskidneys.bsky.social @captainchloride.bsky.social www.nephjc.com/freelyfilter...

Thank you to @asnpublications.bsky.social #JASN for letting us write this. Important topic that's unfortunately devoid of robust data for many of our patients. #nephsky journals.lww.com/jasn/abstrac...

Interesting study in pts w/T1D w/ or w/out flozins and comp. With healthy controls. Less glomerulomegaly on routine biopsies. Flozins impacted metabolic transcripts throughout the nephron - ie the effect wasn’t isolated to the proximal tubule. Showing they are powerful metabolic drugs. #nephsky

If you're applying to a Nephrology fellowship, let @glaucomflecken.bsky.social tell you why you need to come to @pdxkidney.bsky.social. Then let us tell you what makes it such a great and unique training program! #nephsky

Our fellows taste testing tap water vs. RO water! #nephsky

ICYMI @captainchloride.bsky.social on the art of decongestion in heart failure Embracing hypercreatininemia Flozins or Acetazolamide How to use Urine Na+ Do we believe the Italian HTS RCTs? www.youtube.com/watch?v=3m2b... #NephGR

Listening to @captainchloride.bsky.social presenting about decongestion strategies, while escalating all the steps to ultrafiltration 🌊 #NephGR 🌊🌊 Oliguric, overhidrated pt, with an SBP of 270 mmHg, a bit of respiratory alkalosis, and Na 133 @hswapnil.medsky.social

Huge thanks to @hswapnil.medsky.social for the invite and to everyone in Ottawa for the incredible hospitality, I had a great time! As a bonus I got to check out the tulip festival (pics courtesy of swap)

In this Core Curriculum, Nayan Arora and Sarah F. Sanghavi discuss disorders of volume, which are typically identified clinically as changes in the extracellular space, and management strategies through a series of clinical vignettes: bit.ly/Arora24CC (FREE)

Really fascinating talk this morning by Dr. Hiroyuki Nakai regarding AAV vector-mediated gene therapy for Alports disease @pdxkidney.bsky.social

I thought we were past this “Too much protein may also strain the kidneys in those with chronic kidney disease, Dr. Campbell said” www.nytimes.com/2025/04/09/w...

Often consulted after initial correction attempts in hyponatremia.👇called after a 12 mmol/L correction over 8 hrs (primary polydipsia). Previously I would've relowered the Na but with the new data (whether you agree or not) we decided to keep things stable until 24h mark. What would you do? #nephsky

Physiologically it never made sense to fluid restrict HF patients without hyponatremia. No difference in outcomes in 👇study, which was predictable. At the same time - from a study perspective - the actual difference in fluid intake between groups was <300cc/day. pubmed.ncbi.nlm.nih.gov/40159556/

Thanks to Sam Kant for the invite to write this. If you pass your boards because of it then it was worth it! www.sciencedirect.com/science/arti...

Dialysis folks - how accurate is this sat - can I use it to calculate a fick? #nephsky

Who knew? That was sarcastic. @jordybc.bsky.social @hswapnil.medsky.social jamanetwork.com/journals/jam...

So maybe we don’t need to hold flozins before surgery after all? jamanetwork.com/journals/jam...

Announcing the #NephJC internship, @nephjc.bsky.social and @kireports.bsky.social joining forces www.nephjc.com/intern-app for details and to apply! #NephSky

These are not the diuretic trials we need. 2 diuretics will generate more urine then 1 www.sciencedirect.com/science/arti...

You must have heard and read about ‘out of sequence’ organ #transplants from @sumitmohan.bsky.social ‘s work Read this www.nytimes.com/interactive/... in the @nytimes.com with excellent graphics to understand the broken US organ transplant system (free link) #NephSky #MedSky

Giving a talk about heart failure treatment in patients with CKD. 👇 the protocol for our clinic

Not a perfect comparison but interesting nonetheless. Augmented UOP with the intervention vs placebo in CLOROTIC, EMPAG-HF and ADVOR HCTZ: 26% Empagliflozin: 25% Acetazolamide: 12%

Talking about KT/V with KatieOverV @katiekwonmd.bsky.social was most definitely on my nephrology bucket list! Recording @freelyfiltered.bsky.social with @kidneyboy.bsky.social @captainchloride.bsky.social 😎

Comp diuretic studies are rare so worth a look but this observational/retrospective one of chlorthalidone v diamox is not great. Concludes latter is better w/ more wt loss but no sig diff in diuresis or natriuresis. Modest doses of furosemide and no diff in LOS pubmed.ncbi.nlm.nih.gov/36493956/

Finally passed 100,000 learners! 7 modules - 16 hours. No prior training needed. And you'll have all the skills you need to read a medical research article yourself, and make decisions unbiased by what you see on social media. Oh and it's free! https://buff.ly/3ZH8oJN

Saw a new AKI consult, diagnosed malignant obstruction, recommended team consult IR for PCN, signed off #nephsky

If you use diuretics then this is a must read #nephsky www.sciencedirect.com/science/arti...

This would be super impressive if it works out. Wish I had bought the stock yesterday… www.globenewswire.com/news-release...

Anyone using CardioMEMs or other remote hemodynamic monitoring devices in their dialysis patients? #nephsky

Excited to share our core curriculum on volume disorder in @ajkd.bsky.social! Thanks to @sarahsanghavi.bsky.social for writing this with me and @melhoenig.bsky.social for the invitation! www.sciencedirect.com/science/arti...

In pts w/ HF w/out DM what's the risk:benefit of holding SGLT2i (recommended) before a procedure vs not? There is harm in holding flozins for 30 days and the risk of EDKA is low. Main risk being - once held they don't get resumed quickly #cardiosky #nephsky www.ahajournals.org/doi/10.1161/...

Well this should add fuel to the fluid wars...