This work is the first paper issued from a fantastic collaboration with @litinice.bsky.social , Bertrand Llorente and Marco Cosentino Lagomarsino aiming at revisiting the yeast life cycle onlinelibrary.wiley.com/doi/10.1002/.... Hopefully more is coming soon :-)

Last work of the lab showing that Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution | PNAS www.pnas.org/doi/10.1073/...

The climate crisis is accelerating - 2025 looks set to become UK’s hottest year on record. Good to see focus on importance of resilience on #r4today- pls take a moment to sign petition calling on Govt to introduce a fully funded national climate adaptation plan petition.parliament.uk/petitions/73...

I’m excited to share a new postdoctoral opportunity in my lab at Stanford to study the consequences of gene dosage alterations in iPS cells. Check out the posting below and shoot me an email if you’re interested -

Just published in JBC @asbmbjournals.bsky.social - HSV-1 pUL21 teaches us that the universe of protein phosphatase 1 (PP1) binders may be much larger than previously recognised: www.jbc.org/article/S002... Bluetorial at bsky.app/profile/atom... Viruses - is there anything they can't do? 🦠💪

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...

What a great conference #Candida2025 was! So happy about having met so many friendly new faces, and great to have had so much interest in how we do high throughput #proteomics with natural C albicans isolates. Looking forward to fun new collaborations! Thank you @microbiologysociety.org ❤️

New preprint from the lab: we show that the ability to switch mating type was lost at least 13 times independently in the evolution of S. cerevisiae. At least 27% of isolates are heterothallic with a strong association with polyploidy and heterozygosity www.biorxiv.org/content/10.1...

how (yeast) cells re-climb the fitness landscape when they are reprogrammed to a different telomere DNA sequences (human-like)? read the latest from @melaniadangiolo.bsky.social etal , with great help and insights from Eric Gilson, Jonas Warringer and @juliamuenzner.bsky.social (& Ralser lab)

Superhappy to share the last paper from my PhD in @litinice.bsky.social lab. We evolved yeasts with humanized telomeric repeats and discovered that they adapt through amplification of telomere-binding proteins and inactivation of the DNA damage response. www.biorxiv.org/content/10.1...

New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...

Congratulations to our PhD student Amy Wolstenholme for winning the Poster Prize at the EMBL Drug Resistance meeting #EESDrugResistance this week Amy's poster showed that circular DNAs providing copper resistance can be stably transmitted for hundreds of generations in yeast

Goodbye to #EESDrugResistance @embo.org - what a fantastic conference it was! Really cool to see the overlaps between fungal, cancer, and bacterial biology. Thought I'd use the chance to say thank you to the organizers 🙏 and migrate from the evil place to #academic Bluesky at the same time.