Are you using DIA mass spectrometry in proteomics? We have just put this paper online: www.biorxiv.org/content/10.1... Here, we came up with some Recommendations for Quantitative Data-Independent Acquisition (DIA) Proteomics using Controlled Quantitative Experiments (CQEs) 1/4

Very happy that we have been awarded a £800k grant from the MRC for a novel mass spectrometer for the @newcastleuni.bsky.social NUPPA facility. Thanks to everyone involved!

Amazing podcast on the mitochondrial donation babies. Great work by wonderful [email protected] at @newcastleuni.bsky.social and the @lilyfoundation.bsky.social www.theguardian.com/science/audi...

In life sciences there are two types of people in my experience: those that embrace and exploit omics and other large scale data technologies and those who work on one problem at the time. I had many collaborators from either side. 1/2

The financial crisis of the HE sector in the UK now leads to increased numbers of grant and fellowship applications, pushing down the success rates. Since also overheads increased, in some cases we will see success rates halved. There is a BBSRC fellowship which will have a success rate of 5%.

@drandyfrey.bsky.social having quite some interest at his poster at #EUPA2025 We have performed a controlled quantitative experiment with a three proteome mix and come up with recommendations using DIA. Biorxiv paper out soon (hopefully!)

The location and food will make it impossible for anyone else to ever make a better EUPA conference. Thank you for organising such an excellent event! #EUPA2025

Good morning from St. Malo. #EUPA2025

Some of y'all can't handle 2 high agency males going at it and it really shows.

Does anyone have an update on the number of ASMS attendees?

Wow, yes. An amazing glimpse of the LLM Lie Machine at work. Anyone whose students are bring tempted by LLMs, sharing this could be very helpful showing how it lies, and how it fails.

Does anyone know how many delegates are at #ASMS2025 ? I would assume that immigration policy and the blocking of grants will affect the numbers...

Two days left for abstract submission and early bird registration for BSPR2025!

Less than one week to go until the deadline for abstract submission and early bird registration for the British Society for Proteome Research @ukbspr.bsky.social annual conference 2025 in Liverpool! Deadline is Friday May 16! For more details see here: www.bspr.org/annual-meeti...

Who would have thought that hard right nationalist governments do ethnic cleansing and start wars?

Labour dropping Net Zero will lead to Reform voters still voting Reform and Labour voters voting for the Greens. God, show some spine and do what is right.

Sigh. Want to go to two conferences in France and ideally take the train to reduce my CO2 output. To get to Paris I can either spend £500 to take the train or fly for £88. This is so fucked up.

I would like to share our latest work: After years of optimisation, we have developed a flow cytometry-based method to isolate pathogen-containing phagosomes. Paired with sensitive proteomics, this provides exciting new insights into host-pathogen interactions! www.biorxiv.org/content/10.1...

🆕 “Science and medicine in the USA are being violently dismembered while the world watches [...] bullies are only emboldened by acquiescence or indifference.” The Lancet’s latest Editorial: Supporting medical science in the USA www.thelancet.com/journals/lan...

Communication with an autistic teenage boy via text is 99% getting answers like "yes", "no" and "ok". But even that you never get without a prompt.

Journal editors are now receiving such letters from the US government. The entire scientific community must unite to support our journals in flatly resisting such illegal interventions.

Such a great day and opportunity to work together as a UK mitochondrial research community going forward! @mitonewcastle.bsky.social @drperscitus.bsky.social @sarahjpickett.bsky.social @mtrost.bsky.social @jim-ca.bsky.social @newcastleuni.bsky.social @medicalsciencesncl.bsky.social

Very happy to contribute to this amazing group of researchers.

“He made 2.5 million today and he made $900 million. That’s not bad.” Sounds like market manipulation to me. That’s bad.

Two ERC-funded postdoc positions available in the team - one here and second to follow - please repost! jobs.ncl.ac.uk/job/Newcastl...

@chionwurah.bsky.social @cmckinnellmp.bsky.social

It's hard to believe Trump has only been in power for two and a half months. His goals were: – Gaza conflict – Ukraine war – America's economy Everything's going great! And now Iran. 🧨

Excited about Liberation day? ✔️American consumers will be liberated of their money. ✔️Stocks will be liberated from their gains. ✔️ the money gained through tariffs will be used to subsidise areas that lost out due to reciprocal tariffs.

A.must read

Peter Marks’s resignation letter. Everyone should read this.

I wrote about the White House X account — which is steeped in the sociopathic posting style of far-right extremists — and seems to get more sinister and cruel with its posts each week of the administration. www.theatlantic.com/technology/a...

A "chilling" new level of political interference: NIH's solicitations for grant proposals will from now on be reviewed to check if they align with Trump's priorities. www.science.org/content/arti... (by @sarareardon.bsky.social)

Warplans. Hegseth. This reminds me that I have to this GDPR course again.

Heute vor 92 Jahren wurden die ersten 40 Gefangenen in das KZ Dachau verschleppt, ein Grund für ihre Verhaftung wurde ihnen nicht genannt. Weniger als drei Monate nach der Machtübernahme Hitlers hebelten die Nazis damit sämtliche Grund- und Freiheitsrechte aus. Doch Dachau war erst der Anfang. 1/4

@asms.org I assume the venues for the next years are locked in and there is not the possibility to move one of the conferences in the next years to Canada?

Shocking that University of Dundee with its outstanding School of Life Sciences is in such trouble. www.bbc.co.uk/news/article...

If you are visiting the United States, having a negative view of Trump is enough to get you denied entry. If this was coming out of Russia or China, we would deplore such an authoritarian attack on freedom of expression.

This is quite a remarkable two paragraphs. www.wsj.com/finance/curr...

First they came for the Communists* And I did not speak out Because I was not a Communist* … * replace with Gaza supporter

Hassett you liar. Explain this! We know you are not big enough or intelligent enough to apologise so we will just remind everyone of your lies and dishonesty.

DOJ, HHS, ED, and GSA Announce Initial Cancellation of Grants and Contracts to Columbia University Worth $400 Million (government press release) www.gsa.gov/about-us/new...

Make America Vomit Again!

As a German, I always wondered why people of my grandparents' generation did not speak up when the Nazis took bit by bit liberties away and consolidated their power.

🚨🚨 scams related to conferences and invited speakers. 🚨🚨 A "company" will email you about the conference you are speaking at and offer to book your hotels. They will know your details and the dates of the conference from public data. Its a scam. Report it to the organisers and don't reply

Just discovered this song on Spotify which appears to be the right song for our American colleagues at the moment. Sending solidarity! open.spotify.com/track/3DzxzN...

I just cancelled my attendance at the GRC Phagocytes conference in June. This was not an easy decision as it is an amazing meeting and we had a great project to present. However, it just does not feel safe at the moment to go to the US. I urge GRC to organise future meetings outside of the US.

We are delighted to tell you that the registration for BSPR2025 is now live. We have great science, lots of exciting proteomics and amazing speakers lined up, so make sure not to miss out! Plenary speakers: @slavov-n.bsky.social @epetsalaki.bsky.social @vadim-demichev.bsky.social

Don't make deals with fascists!

I think UKRI needs to have a serious look at their grant panels and reviewers. Not only my own experience that more and more outstanding applications get not funded for dubious reasons while I know of total crap applications (so named by the applicants) get funded. 1/3

If you know German, this is indeed a cultural asset. A particular favourite of drunk or stoned students when coming home from a heavy night out.