Just a deer relaxing in a dog bed while the storm rolls in - to brighten your scrolling ⛈

Although cohesin-sensitive, long-range enhancer activation is equivalent in nature to proximal activation. Cooperativity can arise from different levels of activation inputs operating on a non-linear response function. @eliasfriman.bsky.social @uoe-igc.bsky.social www.biorxiv.org/content/10.6...

The supermarket that I shop at employs mentally challenged. They are greeters, baggers, and perform other functions. They are normally pleasant and happy to have a purpose. I like shopping there, it's a reminder that there's room in this world for all of us.

I’m recruiting a new lab manger! Please pass on to anyone who might be interested, and have them reach out to me once they’ve applied. Photo proof of awesome lab to join research-princeton.icims.com/jobs/21793/r...

back when the internet was just all things like this

Postdoctoral openings to investigate how (i) experience-dependent actuators of inhibitory circuit plasticity mechanisms & neurogenesis contribute to memory operations (ii) how a novel lipid signaling mechanism mediates cognitive resilience and regulates healthspan. www.sahaylab.com/publications

The work could help to explain why the risk of developing some brain conditions — such as schizophrenia and Alzheimer’s disease — differs between males and females go.nature.com/48Flrzv

And some love for the human 🧠 for #FluorescenceFriday. I like these zoom outs where you can see a whole structure - here, striatum. Green is MBP and outlining the white matter tracts, 🟣 is DRD1 and if you zoom in (see zooms in following posts) there is 🔴 for RXFP1 marking clusters of island cells.

It shouldn't be a PlotTwist(tm) to reveal that nothing gross happened. This nice gent did not prey on me in any fashion, and I have since come to know more lovely dudes like him. (9)

I’ve always said that submitting a grant proposal is an exercise in hope—not just in terms of being funded, but as a symbol of what it means to dream big and ask exciting questions. Despite everything happening to federal science over the last year, I’m holding on to that hope. Proposal submitted.

Is there a database of the schools with graduate student unions? Didn't any of you make and share a Google sheet?!?! Please rt.

Had an amazing time at World Neuroscience Day yesterday interacting with patients & physicians. Was honored to share science on data-driven interventions for caregiver stress.

My student, Grace Stroman, was selected to present at the 9th Chromatin and Epigenetics Symposium. Her presentation was exceptional! Our keynote speaker @grewalsh.bsky.social was brilliant! Thanks to the organizers, @unclineberger.bsky.social, and @brianstrahl.bsky.social for a remarkable meeting!

This is why we keep going. #scienceisfreedom

Favorite part of travel is connecting with amazing talented friends doing incredible research and training the next gen 🙌🤩🧬🔬🧫 In these tough times, it’s both inspirational and much needed 🥰

The data is in: the NIH goalposts have shifted. What were once almost certain fundable scores have become coin flips and what used to be likely grants have become aspirational, leading to fewer awards. Another manifestation of how HHS policies have led to fewer awards and less science.

This describes some of the 2025 NIH study section changes: public.csr.nih.gov/EvaluationIn...

See public.csr.nih.gov/EvaluationIn...

"Cross-Organ Neuroimmunology of Behavior". Xuanming Guo and I discuss a new framework that reconceptualizes behavior as an emergent property of a distributed, brain-body neuroimmune network. lnkd.in/eihqZ_ay. @sinaiimmuno.bsky.social @sinaibrain.bsky.social

Extremely proud of Rachael @neurohoke.bsky.social and Kiara for this work. I have learned so much working with @talliezee.bsky.social and the whole team.

Comme un igloo Homewood campus, Johns Hopkins University

Yesterday it was cows using tools, today its penguins using satellite imagery.

Just spoke to The Hill about how the dismantling of the NIH is impacting science in America. We still face a cliff of unfathomable heights, w easily 1000+ labs poised to close in the next year due to funding ending. A generation of young scientists lost because there is nowhere for them to train.

big ups to #eneuro @sfnjournals.bsky.social for Reviewer Consultation. Peer review is essential to generating rigorous science and communicating it clearly. Yet authors get bogged down with many requests. #eneuro's approach to address this using reviewer consultation and consensus is a win for all.

Thank you @ericjnestler.bsky.social and Marcelo Wood for the nomination 🤩

To our colleagues at Brown, my heart is broken. I send my deepest sympathy.

Submitted my grant today for the December 8th deadline. Not Dec 10 - I don't have cs anymore since my ss was dissolved. Dec 8 would have been November 19th which would have been November 5th since I had study section on November 12th to 13th which is actually on January 12th to 13th. Any questions?

feeling very inspired serving on study section right now thank you to the pos/sros/etc that are working the long hours

Tomorrow is the last day to register for our in-person event! Join us, and our incredible lineup of speakers, on the UCSD campus Nov 15 from 9am-1pm. Registration is free! docs.google.com/forms/d/e/1F...

@mikefeigin.bsky.social I miss very little about scitwitter but your bagel pics brightened my day! Here is my kids' lunches for today. You can't see the capers because they are tucked safely into the cream cheese UNDER the lox 😉

sometimes as a reviewer you stumble upon the biosketch of someone you really admire, and can just stan for a while

tfw your calendar is devoid of meetings and you wonder if you are supposed to be on a trip

PIs rn www.youtube.com/watch?v=3moR...

Department of Mother Nature: CpG demethylation of the paternal H19-DMR allele decreases Igf2 expression and increases H19 expression through imprinted epigenetic regulation of CTCF binding. www.nature.com/articles/nco...

just finished polishing the chrome on the titanic!

#Psilocybin enhances fear extinction, suppresses fear neurons and recruits extinction neurons in the retrosplenial cortex in mice @flybottleescape.bsky.social @eahellerphd.bsky.social SynapticSoph.bsky.social www.nature.com/articles/s41...

infographics at their best... and worst (lmk paywall issues with link? my dad gifted it to me) www.nytimes.com/interactive/...

So excited to share the work of the fantastic Katarzyna, 1st 🧪PhD student of my lab 🧠, out in @natureneuro.bsky.social 🥂🥳 Cheers to the team, thanks to our precious collaborators and support from @braincanada.bsky.social #CIHR @fondsrechercheqc.bsky.social #newPI www.nature.com/articles/s41...

As someone who has spent the last 25 years studying sex differences in brain function and behavior and the last 10 advocating (loudly) for SABV and working to help my colleagues implement the policy into their work, this is utterly heartbreaking.

Come through!! @pennmedicine.bsky.social

💥 BREAKING: At Apple's 2025 annual meeting of shareholders today, proposal entitled “Request to Cease DEI Efforts" is rejected by shareholders. Right-wing nonprofit National Center for Public Policy Research (NCPPR) proposal was also rejected by Costco shareholders 98-2 percent.

Upon learning that yesterday would be my last day as a program officer at the National Science Foundation, I shared this parting message with my colleagues. The next few months will be frenetic and stressful for them. Here are some things that you can do to help them with the mission ahead. (1)

So very, incredibly proud to have been a McKnight Scholar and so grateful to be connected to a Foundation that values inclusion of people who are so precious to me. (This email made me cry.)

The good news is i saved you 60 billion dollars. The bad news is that is a typo i saved you 600 dollars and also your plane is falling out of the sky

👏👏👏 McKnight Foundation statement: "Despite recent events, actions, and executive orders, we remain steadfast in advancing climate solutions and racial equity across every part of our work, and committed to diversity, equity, and inclusion as core values of our Foundation." 💪💪💪

A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb. https://go.nature.com/41a7Zzj