Another paper bluetorial! Today: how does the spatial location of genes influence their function? (1/n) www.nature.com/articles/s41...

Grateful for the warm welcome @tifrhyderabad.bsky.social :) Thrilled to be part of this vibrant scientific community and eager to build an exciting research program!

So proud of you, @sahanaholla! Watching your journey has been such a joy. Wishing you all the best as you begin this exciting new chapter at TIFRH. They’re lucky to have you!

Remembering Dave’s goodness gives me hope every day.

It was an honor to speak at the Rockefeller University symposium celebrating David Allis—a true visionary who transformed the field of chromatin and gene expression. His legacy continues to inspire us all. Grateful to the organizers for such a meaningful and inspiring event.

What was that you said? You are looking for new #RNA research to read in the weekend? You are in luck! 📣 📣 Check out the new preprint from our lab!!!! 📣 📣 www.biorxiv.org/content/10.1...

Who does that? We rented a train JUST for the conference, that will take the participants from Prague to the woods of Bohemia. There'll be talks ON THE TRAIN. In Prague we'll have 5 locations with different atmospheres. #theconferencetoendallconferences Register now: woodstock.img.cas.cz

What RNA polymerase gets up to in the genome and how mutations happen! Just out in Nature! Many thanks to many collaborators & congrats 1st author Jingjing Liu! www.nature.com/articles/s41...

Our collaboration with the Muir lab revealed that N-terminal histone modifications can 'detoxify' K27M inhibition by altering PRC2-substrate interactions. Acetylation showed the greatest impact, supported by xenograft data from the Monje group. pubs.acs.org/doi/epdf/10....

We used cryoET and biophysical approaches in vitro together with molecular biology in differentiated cells to show that chromatin compacted by PRC1-CBX8 is porous and accessible while PRC1 is dynamic in it. 🧪🧬 #cryoET #Epigenetics #Polycomb www.nature.com/articles/s41...

🔬Decoding Silencing: How Heterochromatin Transcribes to Silence Itself! 🧬 Discover how a pioneer transcription factor-like complex infiltrates repressive heterochromatin, producing transcripts with hidden introns that kickstart RNAi-mediated heterochromatin formation www.nature.com/articles/s41...

Happy New Year 2025! 🎉 As we step into another year of exploration and discovery, may curiosity guide us, innovation inspire us, and collaboration propel us forward. Here’s to breakthroughs, learning, and making the world a better place through science! 🌟 #HappyNewYear

Breaking News: Manmohan Singh, a former prime minister of India who helped transform the country’s economy, died at 92.

In this episode of the Epigenetics Podcast, we talked with @maxvcg.bsky.social from the @ijmonod.bsky.social about his work on epigenetic consequences of DNA methylation in development. #podcast #chromatin #epigenetics Listen here: https://buff.ly/3ZXWGuy

Scared to share this after 10 freaking years of waiting, but here we go: We found that temperature *perception* can change the biology of the next generations, even when “it’s just in the parents' head”. Read how C. elegans neurons control epigenetic inheritance! www.biorxiv.org/content/10.1...

Thrilled to join the amazing community here on Bluesky! 🌟 Kicking off our first post with exciting news: the advanced version of our preprint is now published in Nucleic Acids Research! 🙌 [Read here: academic.oup.com/nar/advance-... Here’s a quick recap of our findings previously shared on X: 👇

“Happy Thanksgiving! 🦃🍁 Wishing everyone a day filled with gratitude, love, and good food! Let’s take a moment to count our blessings and cherish the ones we hold dear 🧡 #Thanksgiving #Gratitude”

📢 Preprint! How does the environment of a father before conception influence offspring? Even more, how do paternal genetics & ages interact with exposures to affect F1 outcome? We tested this systematically, with intriguing findings & some cautionary tales🧵... www.biorxiv.org/content/10.1...

Very happy to see @grothlab.bsky.social , @helink.bsky.social and @grewalsh.bsky.social all migrating over here! All pillars of the the #epigenetics and chromatin community.