Check out this week's episode featuring Dr. Andrew Hogan at @maynoothuniversity.ie! He discusses how #obesity reshapes the immune system and how #GLP1 therapies are transforming treatment. 🎧 Tune in now: https://bit.ly/3T2vFoL

⌛️ 5 days to go! Submit your abstract for our event with @london-immuno.bsky.social here: vist.ly/59p7t

In #ScienceSignaling, scientists review the latest research about the four factors that support the fitness of mucosal-associated invariant T (MAIT) cells—and discuss findings identifying nutrient availability as a fifth pillar of MAIT cell fitness. https://scim.ag/3Q4akKj

Review @andyhogan82.bsky.social @maynoothuniversity.ie Nutrients are important environmental factors that affect the functional responses of MAIT cells to challenge www.science.org/doi/10.1126/...

🚨 New Publication Alert - out now in @science.org - We outline the environmental regulators of MAIT cells including the nutrients they need - with them coming into focus in cancer this is sure to be important - read it here doi.org/10.1126/scis...

Join us in London this September to explore how environmental signals shape immune responses, with speakers including Yasmine Belkaid, Petter Brodin and more. 📅 Abstract deadline: Monday 29 June 2026 🎟️ Register early to save! Learn more: vist.ly/54ad6

Delighted to share our latest paper out today - led by @ardeena-berisha.bsky.social - we show that we can boost the anti-cancer activity of human MAIT cells by getting them to use lactate & also directing them using bi-specific engagers as a proof of concept academic.oup.com/jimmunol/art...

Delighted to see over review and concept on the cover of this month's @cp-trendsendomet.bsky.social where we cover GLP-1s & SGLT2i as anti-inflammatory agents- co-authored with @nickjonesimmuno.bsky.social

📻 Listen back: Prof Andy Hogan, Dept of Biology, was featured in the Laura Dowling Experience podcast where he discussed his work in immunology, obesity, immune health, GLP-1 therapies, his early life plus much more. open.spotify.com/episode/2ORB...

🧬 Have you submitted your abstract for #UKimmunomet26? The deadline is approaching in 3 weeks! Join the UK’s leading immunometabolism meeting in NCL for cutting edge research, international speakers & sessions for ECRs. Find out more & register 🔗 https://bit.ly/493uE45

****2-NBDG does not measure glucose uptake**** Just your regular reminder of this fact 😁. See the rigorous proof of this fact in @lindavsinclair.bsky.social 2020 paper. This paper was 6 years ago!! Stop using 2NBDG to measure glucose uptake already 🙄 pmc.ncbi.nlm.nih.gov/articles/PMC...

My favourite meeting! Brilliant science and even better community!! Recommend for all from new PhD to old Profs

Registrations are now open for 'Fuelling the immune response', the 4th UK immunometabolism meeting, led by the BSI Immunometabolism Affinity Group. Join us in Newcastle on 16 and 17 April 2026 for cutting edge immune metabolism research #UKimmunomet26 Register here: https://bit.ly/493uE45

Seeking a junior scientist for scRNA-seq analytics in Cologne or remotely. If terms like Seurat, DimPlot, or ggplot2 spark recognition—or curiosity—you might be a fit.Flexible $$ Contract, Part time, MSc-to-PhD transition, or PhD project possible. Please feel free to reach out: [email protected]

Studies of T cell acute lymphoblastic leukemia reveal that canagliflozin possesses potent anti-leukaemic effects underpinned by proliferative defects, cell cycle disruption and apoptosis, actions synergized by restriction of serine and glycine www.sciencedirect.com/science/arti...

Compelling metabolic benefits of semaglutide over 30 weeks in patients with schizophrenia Rxed with second-generation antipsychotic agents jamanetwork.com/journals/jam...

MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines www.science.org/doi/10.1126/... @sciimmunology.bsky.social @aliamini419.bsky.social @thelucygarner.bsky.social @nprovine.bsky.social

The new metabolic medicines #T2D #obesity and #inflammation www.cell.com/trends/endoc...

Delighted to share our new review in @cp-trendsendomet.bsky.social on Repurposing metabolic drugs (GLP-1s & SGLT2s) as anti-inflammatory agents! Thanks to @nickjonesimmuno.bsky.social for this joint effort doi.org/10.1016/j.te...

Delighted to have our latest paper now online in Stem Cell Research & Therapy rdcu.be/ezDs3 Congrats to lead co-first authors @courteney.bsky.social @laurabitterlich.bsky.social and collaborators @james Ankrum @andyhogan82.bsky.social @maynoothuniversity.ie

This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥 www.nature.com/articles/s42...

🦠 New research shows obesity disrupts dendritic cell responses to viruses by impairing cytokine production & metabolism - helping explain higher infection risk. 📖 Read the open-access study: https://bit.ly/40kBiiH By @andrea-woodcock.bsky.social‬ et al. ##Immunology

Couple of months into our new social media experiment and we are blown away by the engagement - over 2.6 million views on TikTok alone and the daily feedback both online and in person has been so positive and supportive! A whole new way of spreading research based info vm.tiktok.com/ZNdSrMT71/

Our lab @obesityimmunology.bsky.social is looking to support a stellar scientist in their application to the Marie-Sklodowska-Curie European or Global Fellowship to join us to unravel the impact of obesity on the immune system - DM or email [email protected] for details europa.eu/!B8hjh3

En route home from @kingscollegelondon.bsky.social after 2 days of fantastic science chats! Huge thanks to @peruchalab.bsky.social for the invite and hospitality. Hopefully lots of new collaborations

Obesity is associated with increased susceptibility to infection, which may be due to obesity-induced immune dysregulation. The latest article exchange highlight from @discovimmunol.bsky.social looks at dendritic cell responses to Sendai Virus in a mouse model of diet-induced obesity.

More evidence for GLP-1 medications in limiting rates of cancer. "The findings of this cohort study suggest that GLP-1RAs are associated with reduced risk of developing several hematologic cancers in patients with T2D" jamanetwork.com/journals/jam...

At the Irish Coalition for People living with Obesity's (ICPO) book launch - a child friendly non-stigmatizing introduction to what is Obesity - great initiative

For my immunology followers, the cantrell lab is on bluesky. Applied proteomics, immunometabolism, T cells, protein degradation, signalling what more could you ask for? Give them a follow: @cantrell-lab.bsky.social

Very latest work from @lindavsinclair.bsky.social out today in Nature Immunology www.nature.com/articles/s41...

Changes in body composition following tirzepatide treatment in a substudy of participants from the SURMOUNT-1 trial; the change in body weight, fat mass and lean mass from baseline to Week 72 was −21.3%, −33.9% and −10.9%, consistent across subgroups dom-pubs.onlinelibrary.wiley.com/doi/full/10....

🚨 new paper alert!! Congrats to Andrea Woodcock on delivering this from during the depths of the pandemic! Thanks to @mary-canavan.bsky.social for the collab. Obesity drives dysregulation in DC responses to viral infection academic.oup.com/discovimmuno...

Great new paper from Sandberg group @ki.se in @pnas.org showing IL-10 producing MAIT cells - a population negatively regulated by IL-18 www.pnas.org/doi/10.1073/...

Brilliant presentation from @ArdenaBeirsha from our lab today at #IGCT25 conference @maynoothuni.bsky.social

Our second webinar hosted from USA, will be by Laurent Gapin and Antonia Rotolo. Thursday, February 6th at 16:00 GMT (8:00 Pacific, 11:00 Eastern, 1:00 Friday Tokyo) If you haven't join, get updates and link here: www.cd1mr1.com/cd1-mr1-soci...

New arrivals from X so thought we'd share our most recent paper where we show GLP-1 analogue therapy in people with obesity increases metabolic activity but only in those who loose weight - adding increased energy burn to increased satiety as a mechanism of action doi.org/10.1002/oby....

Delighted to say I have been promoted to Professor - huge thanks to all my lab members present and past - its their hard work and talent that made this happen

This week @eimearrryan.bsky.social from our lab will present the second story from her PhD (only started year 3!) on human MAIT cells metabolism

Shocking investigative piece by #RTEprimetime aired tonight on the black market supply of GLP-1 medications in Ireland - from smuggled pens to clear glass vials with no labels www.rte.ie/news/investi...

www.nature.com/articles/s42... New studies identifying the local inputs to AgRP neurons, reveals a circuit through which GLP-1RAs suppress appetite

Could we see a once a month GLP-1 therapy in the future? Lipidation of semaglutide increased its availability to 36 days and allowed for lower dosing in mice - would further increase its accessibility to people living with obesity! www.pnas.org/doi/10.1073/...

New CD1MR1 Immunology Society is launching with a webinar series on December 3rd, 3pm - 4pm (UTC+1). I'm delighted to be talking about #MAITcells at the first one along with @barrallab.bsky.social (iNKTs) Forward your email & I'll send to S.A.B to be added to the mailing list for the zoom links

Do GLP-1 therapies reduce alcohol intake? Secondary analysis of an RCT participants taking dulaglutide compared to placebo were 29% more likely to reduce alcohol intake. Not conclusive but maybe? www.thelancet.com/journals/ecl...

Obesity imprints adipose tissue even after weight loss - promoting regain and progression. Same is observed with GLP-1 therapies were we see regain in the majority of individuals who stop TX www.nature.com/articles/s41...

More data supporting the cardio protective effect of GLP-1 targeted therapy (this time Tirzepatide led to a lower risk of death from cardiovascular causes or worsening heart failure than placebo www.nejm.org/doi/full/10....

Quick discussion on Ozempic from this weeks RTE drivetime www.rte.ie/radio/radio1...

More strong results for tirzepatide - in participants with obesity and prediabetes tirzepatide TX led to substantial and sustained weight reduction and decreased risk of progression to type 2 diabetes nej.md/48VdDZp

Really looking forward to this interactive public event on all things Ozempic & GLP-1 for Ireland's #ScienceWeek @maynoothuni.bsky.social & online! Myself & Prof Donal O'Shea will discuss the scientific & clinical evidence hopefully busting some myths www.maynoothuniversity.ie/daro/events/...