He’s a doctor 🎉 Congratulations Dr Martin Brennan @princetonmolbio.bsky.social @tbsi-tcd.bsky.social We’re going to miss him so much! Onwards and upwards

Diabetes drug metformin causes weight loss by triggering the production of an "anti-hunger" molecule called lac-phe, also produced after vigorous exercise. #Metformin #WeightLoss #LacPhe #GutBrainConnection

This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥 www.nature.com/articles/s42...

Happy summer from Princeton. Feeling very lucky ☘️🐅

ICYMI: Ascites-derived Lipid Uptake Drives NK Cell Dysfunction in Ovarian Cancer, a #ResearchWatch summary of a new study by @karen--s.bsky.social, @lydialynch.bsky.social, and colleagues at @ludwigcancer.bsky.social @princetonmolbio.bsky.social aacrjournals.org/cdnews/news/...

www.nature.com/articles/s41... @jkuball.bsky.social @sotnom.bsky.social @lydialynch.bsky.social @labminguet.bsky.social

With nearly all of Harvard Chan School’s direct federal grants terminated, we are relying on philanthropy to power our research and support our educational programs. Every gift, regardless of size, advances our vision of health, dignity, and justice for every human. Support our work: hsph.me/whygive

Our paper @sciimmunology.bsky.social shows certain lipids are responsible for the immunosupression of ascites & propose blocking lipid uptake thru SCARB1 may help immunotherapy in ovarian cancer. Wonderful to collaborate with Donal Brennan, Marcia Haigis & super postdoc @karen--s.bsky.social

Researchers led by Ludwig Princeton’s @lydialynch.bsky.social report that certain fats in ascites fluid—which accumulates as ovarian cancer spreads from the ovaries into the abdomen—sabotage anti-tumor immune responses and show how this effect might be blocked for immunotherapy. bit.ly/4jGuUtU

A beautiful day in Princeton @princeton.bsky.social to host our Ludwig Distinguished speaker Dr Kivanc Birsoy from Rockefeller @ludwigcancer.bsky.social

Delighted to have taken part in this project that was published today led by Tomas Ryan’s lab @tjryan.bsky.social @tcddublin.bsky.social @tbsi-tcd.bsky.social ….. mice remember cold 🐭📝❄️

HANG IT IN THE LOUVRE. (President of Mexico on International Women’s Day)

NIH budget: $ 48b Musk wealth: $351b Both are mostly funded by your tax dollars But only one might save your life . . . . Sources: www.nih.gov/about-nih/wh... Search results: elon musk net worth g.co/kgs/6c8YEuB @standupforscience.bsky.social

Thank you to our colleagues in France ❤️🇫🇷❤️🇺🇸❤️ #standupforscience

Thank you to our colleagues @pasteur.fr Paris 🇫🇷🥼🧪 #standupforscience

Thank you to our colleagues in Geneva #standupforscience

Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...

So happy to have @aiinglim.bsky.social as a colleague at Princeton! Her immunology is so exciting and original 😍 Great talk at Princetons ‘Quantitative Immunology’ Symposium today @princetonmolbio.bsky.social

First measles death in Texas. Unfortunately, not surprising. Number of cases likely to increase and we may see more deaths. A tragic, preventable death of a school aged child. But the outbreak is called "not so unusual" by RFK. Simply not true. This is both unusual AND preventable. #vaccineswork

Congratulations to the amazing @karen--s.bsky.social ! And many thanks to @irishcancersociety and Prof Donal Brennan in @ucddublin.bsky.social for continued collaboration on gynaecological cancer research

Almost ready to kick off the 3rd Fusion Mitochondria Conference in DR 🇩🇴🌴☀️🧬🧪🧫 @fusionconf.bsky.social with @MarciaHaigis

Hello DR 🇩🇴 just like Ireland, but 85degrees F! Can’t wait fo r the @fusionconf.bsky.social Mitochondria Conference!

We have to fight now for research that we know benefits all of humanity, we have to stand up for our colleagues at the NIH, we can’t lie down and take it, we stand against this madness #standupforscience2025

No one could be more deserving. The Immunology community is so proud of you @belkaidlab.bsky.social

Fantastic thought provoking talk today by @itaiyanai.bsky.social at 🐅 @princetonupress.bsky.social ….first how we lost our tails against strong pressure, and then how cells develop resistance to drugs 🧫🧬🧪

Thank you to @mcsinton.bsky.social @juanquintana.bsky.social and co-authors for this spotlight on the amazing IL-17 😊

Service to the scientific community @cp-immunity.bsky.social www.cell.com/immunity/ful...

Happy Holidays from the Lynch Lab. Very grateful to work with these wonderful people everyday, and grateful for our first year in @PrincetonUniversity 🐅🥳🎄

Delighted to share our paper on adipose gd T cells making IL-17 every night for homeostasis, coordinating lipid metabolism after eating @natureportfolio.bsky.social Huge effort by whole team and collaborators to work this out. www.nature.com/articles/s41...

She’s here ! 😍

#TickTock 🕰️! Douglas, @lydialynch.bsky.social &co show @ Nature @natureportfolio.bsky.social that IL17 production, especially by gd T cells, has a circadian rhythm impacting lipogenesis. Disruption of the clock or of the IL17 axis alters whole body metabolism & temperature! t.co/wMgOdScsiV