Definitely more important than MHRA suicide risks. Five days ciprofloxacin up to year-long resistance in the gut microbiome (10 % got same gyrA mutation with no fitness cost). Probably had impact on tonic mucosal immune responses too.

Expanded CD4+ T cell clones preferentially adopt a single fate in malaria, and TR1 cells dominate and display long-term memory @sciimmunology.bsky.social www.science.org/doi/10.1126/...

Ex vivo models capture the cellular and functional richness of respiratory tract tissues and enable study of viral pathogenesis www.science.org/doi/10.1126/...

From 2022 to 2023 the city of new york reported a 28% increase in cases of tuberculosis. This article examines the reasons. The biggest one is the continued loss of public health funding. www.healthbeat.org/newyork/2025...

Come get our #immune data, free #FAIRsharing is at @immportdb.bsky.social - from @columbiauniversity.bsky.social @icahn.bsky.social @yalemedicine.bsky.social @stanfordimmunology.bsky.social @benaroyaresearch.bsky.social @lji.org MIT, Seattle Children's #AAI2025 #ImmuneSky #IDsky

Deciphering the role of histone modifications in memory and exhausted CD8 T cells @ejohnwherry.bsky.social @amylizbaxter.bsky.social www.biorxiv.org/content/10.1...

www.nature.com/articles/s41... Proud of my group and collaborators for this work published today in Nature Medicine. We find Cytomegalovirus, which has a profound impact on T cell immunity, is associated with distinct clinical outcomes in patients receiving checkpoint immunotherapy for melanoma.

#Medsky🧪 #idsky #immunodky #pharmasky #publichealth Review discusses how #vaccine #adjuvants function & highlight knowledge gaps that need to be addressed to develop improved vaccines against emerging pathogens. @sciimmunology.bsky.social scim.ag/430weCB

#Medsky🧪#Idsky #immunosky #publichealth A study in @naturemedicine.bsky.social shows how global aircraft-based #wastewater surveillance networks would perform in identifying sources of pandemic outbreaks and what the optimal location of monitoring sites would be. go.nature.com/4gIknMm

An amazing team effort! Thanks to all the eosinophiles involved and @biainfection.bsky.social

I go around saying that tissue repair and tumorigenesis are two faces of the same coin. @ejvillablanca.bsky.social &co now show that this is not always the case and the two processes can be "unlinked" in the gut! @natureportfolio.bsky.social www.nature.com/articles/s41...

Gut IgA1 and IgA2 subclasses co-emerge early in life, largely derive from clonally related and somatically mutated plasma cells in adults, and show unique changes of both frequency and reactivity in IBD @gmagrilab.bsky.social doi.org/10.1084/jem....

Really great review for the ID trainee (and refresher for the ID provider) #IDSky @cidjournal.bsky.social academic.oup.com/cid/advance-...

Posting this because these images are making the rounds again. Plus, someone told me it was the best thing I ever did, and I was flattered. p.s. only possible since I've been directly involved with several papers that meet these exact criteria, so mea culpa blogs.jwatch.org/hiv-id-obser...

Most accurate Oded post ever...

Radiology reports, 2040: brain volumes commensurate with age and genotype. In depth phenotyping of UK biobank cohort never ceases to amaze!

This week in #ScienceImmunology: Olivier Demaria, Eric Vivier, & al. use tetraspecific #NKCell engager (comprising an anti- #NKp46 Ab fragment + #IgG1 #Fc fragment + #IL2 variant + anti- #CD20 Ab) to target #BCell -specific #NonHodgkin #lymphoma (B-NHL) in mouse & NHP models! bit.ly/SI_adp3720

"Why doesn't the NHS use its GP data?". Because of privacy... Because it's hard... But we solved it. We developed new privacy protections... We built docs.OpenSAFELY.org! 181 projects! 31 organisations! Now, they come together, for the first time, in 3D! www.bennett.ox.ac.uk/blog/2024/10...

Physician/scientists, let me know if you want to be added to this list: go.bsky.app/9PwKh1k

Results 10 yrs metagenomic sequencing for CNS infections www.nature.com/articles/s41... Impressive. Key take homes for me. 1) Time to result still long - addressable but a barrier currently. 2) 10% contamination. 3) Despite using cutting edge tests a "causative" organism found in only 15%.

My first post - hi everyone! My lab was intrigued by the interaction between starvation and infrction so med student Jessy Jindal wrote a review, led by senior immunologist Barbara Kronsteiner. Very interesting evolved responses www.sciencedirect.com/science/arti...

Treating lupus by depleting B cells with CAR T cells has been shown successful A breakthrough cancer immunotherapy is now taking aim at autoimmune disease | Science | AAAS www.science.org/content/arti...

Lung Transplantation Review in NEJM Jason D. Christie, Dirk Van Raemdonck, and Andrew J. Fisher www.nejm.org/doi/full/10.... (paywall) Key images / table below #TxID #TransplantSky

Y’all are going to need some infectious diseases experts #IDSky Starter Packs IDSky 1 go.bsky.app/LnAQjdq IDSky 2 go.bsky.app/JNfSvQT IDSky 3 go.bsky.app/FeogT7o IDSky 4 go.bsky.app/D1zxj4E IDSky 5 go.bsky.app/NgGSPeF IDSky 6 go.bsky.app/22VBL8z #MedSky

Wonderful to see the #immunology community growing here. The first starter pack is full (they cap at 150), so I created a second one. Let me know if you'd like to be added go.bsky.app/PY5tCas go.bsky.app/FmERUoD

Tolerance by eviction "we report that, in mice, CD8 T cell tolerance instead results from premature thymic eviction of immature autoreactive CD8 thymocytes into the periphery, where they differentiate into self-tolerant mature CD8 T cells" #Immunology #Immunosky

'In an analysis published in eLife last year, the YCharOS team used this method to assess 614 commercial antibodies, targeting a total of 65 neuroscience-related proteins2. Two-thirds of them did not work as recommended by manufacturers.' www.nature.com/articles/d41...