☕Borsa et al. show that asymmetric #Tcell division after activation requires #autophagy to promote #mitochondria turnover, with T cells inheriting older mitochondria showing decreased degradation, reduced memory potential and altered metabolism. bit.ly/458ODgL

Celebrating #February11 by highlighting Professor Claudia Mauri, the Editor‑in‑Chief of @ceijournal.bsky.social Her leadership and expertise continue to shape the future of immunology. Read the interview on the BSI website here: https://bit.ly/4abuedR ##WomenInScience

This #February11 we are celebrating Prof Jessica Teeling, winner of the BSI Public Engagement Award! Her grant‑supported “Snakes and Letters for a Healthy Brain” project is inspiring conversations on dementia risk + immunity. #WomenInScience Read here: https://bit.ly/3Ktiito

Marking #February11 by celebrating Professor Tracy Hussell, BSI President, and her Nature Mentoring Award for Lifetime Achievement. A great recognition of her commitment to supporting early career researchers and strengthening the immunology community. ##WomenInScience #Immunology

Congratulations to the wonderful Natasha for successfully defending her DPhil thesis! We’re excited to see what comes next for Natasha and her MAIT cell story whilst she continues her project as a postdoctoral researcher🥳👩‍🔬 @kiroxford.bsky.social

New year, new paper! Thrilled to share that our review “Contextualising TH17 cells in cancer” is out now! Congratulations to Declan & team for a fantastic, in depth overview🥳 Go give it a read here: doi.org/10.1038/s415... @natrevimmunol.nature.com @kiroxford.bsky.social

Last night was our Lab Christmas party! Special thanks to Claire and Nick for organising some excellent party games for us (guessing the flavour of Skittles whilst blindfolded is much harder than you’d think!) and to Branca for hosting us🎅🎄🌟 @kiroxford.bsky.social @nickilott.bsky.social

An excellent opportunity, please have a look at the position below!🧫👩‍🔬

We’re hiring! Two postdoctoral research positions are available in our lab - one in mucosal immunology, and one in exposome immunology (MRC CoRE)! Apply by December 22nd!🎄 Position 1: tinyurl.com/2mh44tn4 Position 2: tinyurl.com/5ffzxsfb @kiroxford.bsky.social @exposomeimmunology.bsky.social

Congratulations to our fantastic DPhil student, Henry, for defending his PhD thesis today!! It’s been a pleasure to have Henry in the lab & we miss him already! Go check out the review (linked below) if you’d like to see some of his work🥳🧑‍🔬 @kiroxford.bsky.social pubmed.ncbi.nlm.nih.gov/40252635/

We’re very proud of our very own Dr Alice Bertocchi for winning a Kennedy Trust Transition Fellowship! Keep up the amazing work as always, Ali!🥳❤️

We are hiring a Postdoctoral Research Assistant to study how microbiomes influence barrier biology and shape responses to viral infection! This post is part of the exciting new MRC CoRE in Exposome Immunology. Apply by December 18 👇 www.kennedy.ox.ac.uk/jobs/postdoc...

Day 4 and the final day of the BSI saw a fantastic talk from @labliston.bsky.social about Tregs in the brain and an excellent session devoted to “Barriers, bugs, and breakdowns” - right up our street! Thank you to all organisers and presenters @britsocimm.bsky.social for a great week in Liverpool🫶

Day 3 of the BSI was a busy one, with Yuqing & Dehui presenting posters, and Ffion giving an excellent talk all about AMR Klebsiella dynamics in the gut! It was also great to see Dave Withers give a fantastic plenary talk!🧫🧬 @dehuic.bsky.social @yuqinglong.bsky.social @witherslab.bsky.social

Day 2 of the BSI saw Gemma & Rachel from the lab presenting posters, as well as the lovely Anna Ahlback from the Maloy lab delivering a great talk on Hh infection and its impact on DSS colitis (go check out their new preprint!)👩‍🔬 @gemmala.bsky.social @rachelanscombe.bsky.social @aahlback.bsky.social

Day 1 of the BSI 2025 on Monday saw the wonderful Judi Allen deliver a fabulous keynote talk! We were also very excited to see Judi share the news of our new MRC Exposome Immunology Manchester/Oxford collaboration👩‍🔬 @profjudiallen.bsky.social @exposomeimmunology.bsky.social @britsocimm.bsky.social

Delighted to share that Fiona was awarded the FSI EFIS-IL Lecture Award last week as a keynote speaker at the 56th Annual Meeting of the French Society for Immunology! We’d like to warmly thank the SFI for the award, it was a pleasure to attend!🇫🇷👩‍🔬 @sfi-immunologie.bsky.social @kiroxford.bsky.social

We’re thrilled to share that we’re part of the Experimental Medicine Collaboration (EMC) with GSK! The EMC will put translational science at the forefront of developing treatments for immune mediated inflammatory diseases👩‍🔬🧬🧫 www.ox.ac.uk/news/2025-11... @gsk.bsky.social @kiroxford.bsky.social

Some pics from our annual lab autumn walk! We went to the lovely Blenheim palace to get some steps in & enjoy the autumn leaves🍁🚶‍♀️🌳

A great afternoon celebrating the award of our MRC CoRE in person. We heard about projects spanning our discovery pipeline, from ExWAS and mechanistic barrier immunology, to potential therapeutic angles for IBD and machine learning for diagnostics. #exposome #immunology

Interested in joining the Powrie Lab? We’re looking for a Postdoctoral Researcher to study the neutralisation capacity of human anti-IL-10 autoantibodies. You’ll be part of our new MRC CoRE in Exposome Immunology!🧫🦠 Find out more here & apply by 11th Nov: bulletin.ndorms.ox.ac.uk/c/126QDJVBd0...

Throwing it back a few weeks to the final meeting of the CRUK grand challenges optimisticc study! We had a great time in Boston discussing progress in the colorectal cancer & microbiome field - it’s been a real pleasure being part of this group!🧫🫶 @elayton13.bsky.social

We’re delighted to hear that our favourite cell type (Regulatory T cells!) have been recognised in the Nobel Prize this year! Huge congratulations to Mary, Fred, and Shimon for their pivotal work in the field & here’s to many exciting Treg advances to come!🥳👏🎉

A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine

Happy #treg day everyone - congratulations to Mary Brunkow, Fred Ramsdell, Shimon Sakaguchi and to all the immunologists who have contributed to this incredible field. See our collection: www.nature.com/collections/...

September meant it was the Powrie labs turn to organise an institute social! We hosted “The Great Kennedy Bake Off” and had lots of tasty entries, as well as a cake decorating competition! Congratulations to our winners - Lynn for best bake and Osheen for best decorating!🍰🍪🧁 @kiroxford.bsky.social

We had a fab time at our student symposium (KISS2025) this week! We really enjoyed everyone’s talks and poster presentations, with some super exciting keynote speakers! Amit, Natasha, and Rachel gave great overview talks and poster presentations on their DPhil projects👩‍🔬🧠 @kiroxford.bsky.social

#PooTriviaQuiz is coming up for #BiologyWeek Sponsored by Wooclap - helps people teach and learn. Register at pootriviaquiz.eventbrite.co.uk It's free and family-friendly but you do need to register to reserve a space on the Zoom call.

WE ARE HIRING! www.manchester.ac.uk/exposome-jobs Vacancies inc. 3x PDRA positions, 2x data scientists and a Transition Fellowship in Air Pollution. Join us as we embark on a 14 year journey to understand how the exposome impacts immune regulation and chronic inflammation. #hiring #immunosky

🎓 6x fully-funded 4-year PhD studentships 🎓 We are recruiting our first cohort of PhD students to start Oct 2026. Students will shape their own projects within supervisory teams spanning the universities of Manchester & Oxford. www.findaphd.com/phds/program/mrc-core-in-exposome-immunology/?p6899

We had a great time at Kennedy Lab to Clinic conference this week! It was especially exciting to be there for a session devoted entirely to Regulatory T cells🧫💉 @kiroxford.bsky.social @ndorms.bsky.social

We had a fab time running The Gut Florists stall at Green Man Festival! From talking all things microbiome, painting gut microbes, making bacterial pom-poms, or doing microbe word searches, we had something for everyone & loved chatting to you!🧫💐🦠🌼 @britsocimm.bsky.social @greenmanfest.bsky.social

Some very exciting news to share!!

If you haven’t already signed up to The Microbiome Innovation One Health Conference 2025 yet, this is your reminder to! Based in Oxford on the 15th/16th of September, it’ll be a great opportunity to get up to date on recent progress in the field of Microbiome Science🦠🧫 web.cvent.com/event/9d50cf...

It was great to see Amit, one of our final year DPhil students, presenting his work at the BBSRC Interdisciplinary Bioscience DTP symposium last week!☀️ @amit-halkhoree.bsky.social @kiroxford.bsky.social

Happy World Microbiome Day! We celebrated this year with some delicious petri dish cheesecakes, with everyone “streaking” some plates whilst learning about the microbiome!🧫🍰 @microbiologysociety.org @kiroxford.bsky.social @ndorms.bsky.social

So nice to have the work from my PhD on faecal microRNAs featured in The Scientist magazine www.the-scientist.com/profiling-mi...

It’s been a great week in Prague for the Food, Microbiota, and Immunity conference! Claire gave a great talk and Dehui won an award for her poster presentation👏☀️🦠 #FMI2025 @dehuic.bsky.social

We had a great time showing off our fabulous Gut Wall and making microbe pom poms with members of the public at the BRC Health Research Showcase last week at Oxford’s Westgate shopping centre!🧫🦠 @oxfordbrc.bsky.social @kiroxford.bsky.social @gemmala.bsky.social @amit-halkhoree.bsky.social

Sharing some more pics from a fantastic week in Alghero for the ENII Advanced Immunology Summer School - we are all very sad to be leaving sunny Sardinia behind! Thanks to the wonderful organisers and speakers for an amazing week👩‍🔬🇮🇹🧑‍🔬 @efis-immunology.bsky.social

Members of the lab have been having an excellent week at the ENII Summer School for Advanced Immunology! Tarrion, Emma, Rachel, and Sumaiya have presented their work as some great short talks and posters☀️🇮🇹

Shoutout to our wonderful postdocs, India and Avery, for giving a fab talk at Pint of Science this week!🧬🍺👩‍🔬 @pintofscience.uk @indiabrough.bsky.social @kiroxford.bsky.social

Why is the speed of your gut important for your microbiome and gut health? An overview I wrote with @theconversation.com theconversation.com/how-fast-is-...

Very pleased to have been awarded a grant from the @ox.ac.uk Returning Carers' Fund to support me in my journey learning data science based at the @kiroxford.bsky.social, @ndorms.bsky.social. #bigdata #bioinformatics www.medsci.ox.ac.uk/research/int...

More good news this week - awarded a Junior Research Fellowship with @kelloggoxford.bsky.social starting Michaelmas term. A dream come true for a scientist with an educational pedagogy leaning. Looking forwarded to meeting the many #teachers in training and graduate students. #lifelonglearners

We had a great day at the lovely Wytham Woods Chalet for our lab retreat this year! A special thanks to Prof David Withers @witherslab.bsky.social for joining us for an excellent guest talk☀️🌳

Thanks to the Gulbenkian Institute for Molecular Medicine @gimmfoundation.bsky.social and Joana Bom for hosting us in Oeiras last week, even if the weather wasn't perfect!☔️👩‍🔬

Our first post on Bluesky! Throwing it back to two weeks ago at the #IMMOX’25 Genetic Variation & Barrier Immunity Conference - various lab members presented their work, with @gemmala.bsky.social and @fabsal.bsky.social giving fantastic talks!🧬👩‍🔬