Dave Root
@neuronroot.bsky.social
📤 1685
📥 1350
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Neuroscientist at CU Boulder. he/him. Mostly amplify other neuroscientists. www.root-lab.org
pinned post!
New Pre-Print led by
@emilyprevost.bsky.social
Glutamate-dopamine, nonglu-dopamine, and glu-only neurons and neurotransmitters they use have dissociable contributions to motivated behavior. Important to segregate DA subcell-types to better understand the many motivation-related functions of DA
add a skeleton here at some point
12 months ago
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Susanna Molas
about 12 hours ago
🚨 Please share! My lab is hiring a Research Assistant! This is a great opportunity to gain experience with cutting-edge systems neuroscience techniques in a collaborative research environment. If you're interested, check the link for further details:
jobs.colorado.edu/jobs/JobDeta...
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Vijay Mohan K Namboodiri
1 day ago
Very excited to post our paper led by
@daburke.bsky.social
www.nature.com/articles/s41...
where we uncover a simple mathematical rule underlying how brains learn that a cue predicts a reward. 1/26
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Duration between rewards controls the rate of behavioral and dopaminergic learning - Nature Neuroscience
Cue–reward learning rate scales proportionally with the time between rewards. Consequently, learning over a fixed duration is independent of the number of trials. This challenges trial-based dopamine ...
https://www.nature.com/articles/s41593-026-02206-2
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Steven R. Shaw, PhD
2 days ago
Now this is a movie plot!!! Someone understands grad school.
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Matthijs Dorst
4 days ago
Please share: I am recruiting a PhD student to join my lab in Oslo! For this project, we will investigate the role of striatal interneurons during action selection, using a combination of behavior, in vivo voltage imaging, and slice ephys.
www.jobbnorge.no/en/available...
#NeuroJobs
#NeuroSkyence
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bioRxivpreprint
3 days ago
Chronic nicotine reduces nigral dopaminergic activity and remodels pedunculopontine cholinergic subpopulations
https://www.biorxiv.org/content/10.64898/2026.02.12.705607v1
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Yoav Livneh
4 days ago
New lab preprint! Can we study conscious perception of gut sensations in mice to reveal its neuronal basis? Can we train mice to report their gut sensations? Omer Rafael and Stav Shtiglitz in the lab teamed up to discover that…YES! Thread…1/6
www.biorxiv.org/content/10.6...
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https://www.biorxiv.org/content/10.64898/2026.02.11.705298v1
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Travis Goode
4 days ago
Restaurants, billboards, commercials… what brain circuits link context to appetite? 🧠🌎🍽️ Very happy to finally share a major update in our work exploring the hippocampus and lateral septum in calibrating food consumption! 🍩 Major thanks to our lab and collaborators! ⭐️⭐️
www.cell.com/neuron/fullt...
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A dorsal hippocampus-prodynorphinergic dorsolateral septum-to-lateral hypothalamus circuit mediates contextual gating of feeding
Goode et al. show that prodynorphin (Pdyn)-expressing neurons of the dorsolateral septum (DLS) receive substantial dorsal hippocampal (DHPC) input and inhibit lateral hypothalamic (LHA) GABAergic neur...
https://www.cell.com/neuron/fulltext/S0896-6273(26)00050-4
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someone should make a tool and name it ChatGFP
4 days ago
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Leah Mayo
4 days ago
Congrats to
@pact-lab.bsky.social
postdoc
@ryanntansey.bsky.social
on her recent paper looking at the impact of elevated anandamide via FAAH inhibition on brain function in patients with PTSD What does it do? Well....not much 😬
www.nature.com/articles/s41...
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Functional neuroimaging of fatty acid amide hydrolase inhibition in posttraumatic stress disorder: a randomized clinical trial - Translational Psychiatry
Translational Psychiatry - Functional neuroimaging of fatty acid amide hydrolase inhibition in posttraumatic stress disorder: a randomized clinical trial
https://www.nature.com/articles/s41398-026-03864-3
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Dave Root
Siegenthaler Lab
5 days ago
Scientist's way of saying 'I ❤️ you' "I found this paper/preprint that made me think of your project." "I checked the mice/cells/plates already." "I just sent you the edits you requested." "I have a slide/diagram that will work for that." "I had that problem with [lab equipment], I have a fix."
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Hubble or cluster cut?
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9 days ago
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Abby Polter
10 days ago
First of a few postings for jobs in my lab-we are hiring an entry level technician!
www.gwu.jobs/postings/124...
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Research Assistant
This Research Assistant position contributes to research/development by assisting with experiments in a controlled laboratory setting. The core responsibilities of this position include assisting with...
https://www.gwu.jobs/postings/124193
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Sofiya Hupalo
14 days ago
Excited to share this preprint of my postdoc work, only several years late to the party 🎉 We examined how loss of function in SETD1A, a high confidence schizophrenia risk gene, impacts neural synchrony across circuits supporting working memory in mice.
www.biorxiv.org/content/10.6...
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https://www.biorxiv.org/content/10.64898/2026.01.29.702577v1
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bioRxiv Neuroscience
14 days ago
Divergent ethanol drinking phenotypes are linked to region-specific dysregulation of serotonin systems in the mouse brain
https://www.biorxiv.org/content/10.64898/2026.01.30.702832v1
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Merriam-Webster
17 days ago
❤️
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Joao Barbosa
20 days ago
Postdoc position in Paris: come help develop new generation human brain computer interfaces ⚡🧠💻 Interested? Contact me if you have experience with machine learning (e.g. simulation-based inference, RL, generative/diffusion models) or dynamical systems. See below for + details and retweet 🙏
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Navin Pokala 🇺🇸🇺🇦🇨🇦🇬🇱
21 days ago
Very few people in the history of our species have saved as many people's lives as William Foege, who designed and lead the global elimination of smallpox, a highly contagious disease that killed 1 out 3 people it infected. ✊
www.scientificamerican.com/article/smal...
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Scientist who helped eradicate smallpox dies at age 89
A leader in the global fight against smallpox and a champion of vaccine science, William Foege died last Saturday
https://www.scientificamerican.com/article/smallpox-eradication-champion-william-foege-dies-at-89/
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Dave Root
bioRxiv Neuroscience
25 days ago
Ventral pallidal perineuronal nets regulate opioid relapse
https://www.biorxiv.org/content/10.64898/2026.01.21.700926v1
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bioRxiv Neuroscience
26 days ago
Memory erasure by dopamine-gated retrospective learning
https://www.biorxiv.org/content/10.64898/2026.01.17.700100v1
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I hate to admit it but exercising does make me feel better
28 days ago
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Ishmail Abdus-Saboor
about 1 month ago
Exciting new preprint on oxytocin neural circuits for massage led by Manon Bohic in Vicky Abraira’s lab. Sasha and I were glad to contribute imaging experiments to this collaborative effort, spanning mice to humans. Vicky is a master at bringing people together.
www.biorxiv.org/content/10.6...
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Oxytocin Modulation of Spinal Circuits Drives Therapeutic Benefits of Massage
Across social species, social touch enhances well-being and reduces pain - two seemingly distinct benefits that enhance survival. Yet where and how the nervous system integrates these functions, and w...
https://www.biorxiv.org/content/10.64898/2026.01.11.698886v1
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John Pearson
about 1 month ago
My department, Duke Neurobiology, is searching for a new chair. Ad below. Come work with me,
@jmgrohneuro.bsky.social
@ennatsew.bsky.social
@jorggrandl.bsky.social
@jnklab.bsky.social
@sbilbo.bsky.social
@neurocircuits.bsky.social
and many other amazing folks!
@dukemedschool.bsky.social
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Department Chair, Duke Neurobiology - Duke University, Durham job with Duke University - School of Medicine | 12852576
The Duke University School of Medicine (SOM) seeks a distinguished neuroscientist to serve as the next Chair of the Department of Neurobiology.
https://www.nature.com/naturecareers/job/12852576/department-chair-duke-neurobiology/?TrackID=82063&BatchID=1049&JobAlertId=103171&cmpid=JBE_TL_20260113_jobtitle&utm_source=jbe&utm_medium=email&utm_campaign=JBE_TL_20260113_applynow_job1
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Tatjana Tchumatchenko
about 1 month ago
Please spread the word🔊My lab is looking to hire two international postdocs. If you want to do comp neuro, combine machine learning and awesome math to understand neural circuit activity, then come work with us! Bonn is such a cool place for neuroscience now, you don't want to miss out.
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Namnezia 🥑
about 1 month ago
From the bottom of page 9 of my (rather lengthy) course syllabus:
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Ms. podman
about 1 month ago
This wheel is to the boy squirrel the way that the football is to Charlie Brown and it still makes me laugh every time he tries to use it only to be immediately spun.
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Spencer LaVere Smith
about 2 months ago
Protip: The *earlier* you fill out your availability, the more plausible it is for you to say later, "Sorry, I'm no longer free then. Go ahead and meet without me."
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Artologica aka Michele Banks
about 2 months ago
People of Bluesky! Are you ready for the Top Squirrels of 2025??????
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Bryan Roth
about 2 months ago
Postdoctoral fellowship available in structure guided drug discovery in @RothLabUNC Please RT
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The Transmitter
about 2 months ago
Adam Kampff prioritized spreading knowledge over publishing flashy papers in prestigious journals, but colleagues say his mark on neuroscience was undeniable. The researcher and educator passed away on 9 December. By Lauren Schneider
www.thetransmitter.org/systems-neur...
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Remembering Adam Kampff, neuroscience educator and researcher
Kampff’s do-it-yourself approach inspired a generation of neuroscientists.
https://www.thetransmitter.org/systems-neuroscience/remembering-adam-kampff-neuroscience-educator-and-researcher/?utm_source=bluesky&utm_medium=org-social&utm_campaign=20251224-obit-adam-kampff
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Dave Root
Abhi Aggarwal
about 2 months ago
iGluSnFR4 is now available
@natmethods.nature.com
www.nature.com/articles/s41...
Glutamate indicators with increased sensitivity and tailored deactivation rates 🧪
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Glutamate indicators with increased sensitivity and tailored deactivation rates - Nature Methods
iGluSnFR4f and iGluSnFR4s are the latest generation of genetically encoded glutamate sensors. They are advantageous for detecting rapid dynamics and large population activity, respectively, as demonst...
https://www.nature.com/articles/s41592-025-02965-z
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Tom Kash
about 2 months ago
New work from kashlab led by Dr. Jobe Ritchie
@jobeneuro.bsky.social
.. our old pal serotonin is back.
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PSA: the super flu is no fun at all
about 2 months ago
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SfN Journals
about 2 months ago
#eNeuro
: Doyle et al. created the Alcohol Biobank, a collection of biological samples from over 700 genetically diverse rats tested for addiction-like behaviors, helping researchers explore genetic, molecular, & neurobiological factors in addiction.
https://doi.org/10.1523/ENEURO.0207-25.2025
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Allen Institute
about 2 months ago
🚨 Our year-long, post-bacc internship positions are now open for application! 🚨 This new program is designed to provide mentorship and on-the-job experience for recent grads. Full list of open roles:
https://alleninstitute.org/careers/internships-and-postbac/
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Dave Root
Tim Onion
2 months ago
Sincerely one of the funniest things the WSJ has ever written or done.
www.wsj.com/tech/ai/anth...
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Andrew Pruszynski
2 months ago
If you're (1) into nhp neurophysiology and/or biological motor control, (2) a foreign big shot and (3) interested in moving here, please reach out -- this new program looks extremely attractive (min. $8M over 8y)!
www.uwo.ca/research/can...
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Canada-Impact-Plus - Research - Western University
https://www.uwo.ca/research/canada-impact-plus.html
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Jorge Miranda Barrientos
2 months ago
So happy to share this preprint and so proud of
@rehg-j.bsky.social
and his hard work and determination. Here we showed circuit-specific effect after activation of mPFC-LC projectors to sustained attention during rCPT.
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Lindsay Schwarz
2 months ago
Thrilled this is out, led by former PD Cameron Ogg (now with her own lab at
@rhodescollege.bsky.social
!). It was a driven by a desire to see, in real-time, how LC activity/NE release influences downstream targets in behaving animals. SO hard to do, but Cameron did it!
www.cell.com/cell-reports...
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Locus coeruleus norepinephrine neurons facilitate orbitofrontal cortex remapping and behavioral flexibility
Ogg et al. use in vivo imaging techniques to record activity in the locus coeruleus (LC) and the orbitofrontal cortex (OFC) during a reversal learning task in freely moving rodents. They show that man...
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01459-7
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Nicola Sambuco
2 months ago
½ New preprint reveals a twist in dopamine’s role: Cue-evoked dopamine in the Nucleus Accumbens core doesn’t just boost reward pursuit—it shapes how we pursue.
#RewardSignals
#neuroskyence
doi.org/10.1101/2025...
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Dopamine supports reward prediction to shape reward-pursuit strategy
Reward predictions not only promote reward pursuit, they also shape how reward is pursed. Such predictions are supported by environmental cues that signal reward availability and probability. Such cue...
https://doi.org/10.1101/2025.08.22.671841
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Catherine Dulac
2 months ago
New paper alert!!...🤩 Led by
@blogeman.bsky.social
, we identify how cell type-specific hormonal responses in the hypothalamus tunes parenting behavior in males and females 🐭🧠🍼. Highlights in thread 👇 1/6
www.biorxiv.org/content/10.6...
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Cell Type-Specific Hormonal Signaling Configures Hypothalamic Circuits for Parenting
Parenting behavior emerges from hormonally sensitive circuits, but how distinct circuit components are affected by, and contribute to, sex and state dependent changes in infant caregiving remains uncl...
https://www.biorxiv.org/content/10.64898/2025.12.11.693766v1
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Ed Boyden
2 months ago
We are hiring a lab manager, for our research group, the Synthetic Neurobiology group (aka Boyden Lab) at MIT/HHMI (on the MIT campus, Cambridge, MA)! Please apply if you're qualified and interested, and spread the word!
hhmi.wd1.myworkdayjobs.com/External/job...
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Laboratory Manager II - Boyden Lab
Primary Work Address: 77 Massachusetts Avenue, Cambridge, MA, 02139 Current HHMI Employees, click here to apply via your Workday account. The Synthetic Neurobiology Group (Boyden Lab) at the MIT McGov...
https://hhmi.wd1.myworkdayjobs.com/External/job/Massachusetts-Institute-of-Technology/Laboratory-Manager-II---Boyden-Lab_R-4000
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Shelly Flagel
2 months ago
Excited to share our new GLP-1 receptor agonist study! Chronic semaglutide potentiates motivation for small food rewards and associated cues, but reduces intake when food is freely available—surprising twist!
#GLP-1
,
#behavior
#neuroscience
#pharmacology
1/ 🔗
www.biorxiv.org/cgi/content/...
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Chronic semaglutide treatment enhances the incentive motivational value of a small food reward and associated cue in male and female rats
Rationale: Glucagon-like peptide-1 (GLP-1) receptor agonists, such as semaglutide, are increasingly utilized in clinical practice due to their efficacy in promoting sustained weight loss following chr...
https://www.biorxiv.org/cgi/content/short/2025.12.06.692775v1
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David Moorman
2 months ago
Lecturer position in Neurobiology at UMass Amherst. Come join a great group of instructors teaching in the Biology, Psych & Brain Sci, and Neuroscience majors. Review starts Jan 5, 2026. Please forward/apply!
careers.umass.edu/amherst/en-u...
#NeuroJobs
#Neuroscience
#AcademicJobs
#HigherEd
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Current Biology
2 months ago
A high
#fat
#diet
increases risk taking and suppresses escape neurons in🐁🐁🐁
#neuroscience
www.cell.com/current-biol...
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High-fat food reinforces risk taking by suppressing defensive neurons
This study by de Araujo Salgado and Krashes reveals how high-fat diets suppress defensive neural circuits, driving riskier foraging in the presence of predation. The findings highlight how high-fat fo...
https://www.cell.com/current-biology/abstract/S0960-9822(25)01522-2
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Tom Kash
2 months ago
🧠 We're hiring! 🧠 Are you passionate about neuroscience and education? Join our faculty at UNC Chapel Hill to inspire and teach the next generation of neuroscientists. Apply now: 🔗https://unc.peopleadmin.com/postings/308455
#Neuroscience
#TeachingJobs
#AcademicJobs
#HigherEd
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Yulong Li Lab
2 months ago
(1/3)Excited to share PKU tags—our lab’s latest contribution expanding the toolkit for cell-type labeling with a new shape dimension! Developed at PKU, these genetically encoded tools enable multiplex cell-type labeling compatible with both light and electron microscopy.
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Tom Kash
2 months ago
In
@elife.bsky.social
: Sex differences in BNST signaling and BNST CRF in fear processing
doi.org/10.7554/eLif...
Official version finally out. Thank you to reviewers, made it better!
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Sex differences in BNST signaling and BNST CRF in fear processing
Critical differences in how the BNST responds to different types of fear across male and female mice.
https://doi.org/10.7554/eLife.89189
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Matt Geramita
2 months ago
Excited to share my postdoc work with
@yttrilab.bsky.social
and
@ahmarilab.bsky.social
where we show that the striatal indirect pathway mediates hesitation in mice (
www.nature.com/articles/s41...
). And I'm honored to have
@ahmarilab.bsky.social
introduce the findings with a musical abstract!
add a skeleton here at some point
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Oded Rechavi
3 months ago
Closing tabs with papers I promised myself i'll read
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Magdalena Skipper
3 months ago
The world has lost a giant of virology, molecular biology and science advocacy David Baltimore’s obituary by Stephen Goff
www.nature.com/articles/d41...
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David Baltimore obituary: virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS
The protein, reverse transcriptase, has become an essential tool for making DNA copies of RNA.
https://www.nature.com/articles/d41586-025-03862-3
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