Ian Henderson
@hendersi.bsky.social
📤 2021
📥 1856
📝 121
Plant genetics and epigenetics @ University of Cambridge, Department of Plant Sciences
reposted by
Ian Henderson
Ben Williams
about 20 hours ago
We have been cooking up this story for a while and we are excited to finally be able to share! Read on if you're interested in whole plant regeneration WITHOUT the application of hormones!
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www.theguardian.com/environment/...
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Cambridge offers botany course that inspired Darwin after rare archive uncovered
University’s botanic garden will use study materials created by John Stevens Henslow, the naturalist’s mentor, 200 years ago
https://www.theguardian.com/environment/2026/mar/28/cambridge-university-botany-course-charles-darwin-john-stevens-henslow
4 days ago
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Ian Henderson
Brett Baker
19 days ago
Having a hard time keeping up with the fast-moving field of origin of eukaryotes/Asgards archaea? Our new perspective article can help, we review the status of research over the last decade and where it's going. The archaeal roots of eukaryotic life
www.pnas.org/doi/10.1073/...
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Ian Henderson
James McCulloch
29 days ago
Why do the chromosomes of cyperids (sedges & rushes) split and fuse so regularly on evolutionary timescales? Is it because they have so many centromeres? Our new preprint, the first major paper of my PhD, addresses this question. 🧵⬇️ 1/12
www.biorxiv.org/content/10.6...
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Ian Henderson
James McCulloch
29 days ago
Thank you to my co-authors:
@marcelauliano.bsky.social
,
@charlottewright.bsky.social
,
@hendersi.bsky.social
, Sam Ebdon,
@kamilsjaron.bsky.social
& Mark Blaxter. Finally, this would not have been possible without the Darwin Tree of Life sequencing & assembly teams
@sangerinstitute.bsky.social
! 🧵12/12
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reposted by
Ian Henderson
The Loke Centre for Trophoblast Research
3 months ago
Exciting News! 🚀 Registration Open! | Loke CTR Annual Meeting 2026 🎉 📅 16-17 July 2026 📍 St John’s College, Cambridge | 💻 Hybrid conference (in-person & online) 🔬 Epigenetics of embryogenesis and placentation 📌 To find out more and to register
www.trophoblast.cam.ac.uk/ctrconferenc...
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reposted by
Ian Henderson
Genetics Society of America
about 1 month ago
A new study in
#GENETICS
from
@hendersi.bsky.social
’s group explores how natural variation in
#Arabidopsis
influences centromere-proximal crossover frequency and segregation distortion when
#centromeres
are heterozygous.
buff.ly/Ev5Xrro
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reposted by
Ian Henderson
Genetics Society UK
about 2 months ago
Come celebrate our Anniversary Day in Edinburgh, 25 & 26 June! Join us for talks from our Honorary Members, Prize & Medal winners, and our Summer Students. Programme & registration details:
genetics.org.uk/events/anniv...
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Lovely gift of Xiao Qing Gan tea which I shall enjoy!
3 months ago
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Repetitive seashore?
3 months ago
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3 months ago
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reposted by
Ian Henderson
Michael Brockhurst
3 months ago
Manchester Institute of Biotechnology is looking for a new Professor. There are a few priority areas including microbial engineering (broadly defined, from pathways to cells to microbiomes). Closing 12 Jan. Join us in the best city in the UK 😜
www.jobs.manchester.ac.uk/Job/JobDetai...
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Professorial Appointment within the Manchester Institute of Biotechnology:Manchester Institute of Biotechnology
Applications are invited for a professorial appointment to be based in the Manchester Institute of Biotechnology (MIB) at the University of Manchester (UoM). The successful candidate will join a dynamic research environment at an exciting time and will help shape the institute research priorities and national/international profile. We are open to high quality applications from across the broad engineering biology and biotechnology landscape. Specific areas of interest include but are not limited to chemical biology of disease related proteins, natural product biosynthesis and enzyme discovery; structural biology and mechanistic enzymology; and microbial engineering.
https://www.jobs.manchester.ac.uk/Job/JobDetail?JobId=33867&source=JobTrainRSSFeed
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reposted by
Ian Henderson
School of Biological Sciences
4 months ago
Read more about the projects:
www.cam.ac.uk/research/new...
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Eight Cambridge researchers awarded €17 million in ERC Consolidator Grants
Funding from the European Union’s Horizon Europe programme will support promising mid-career scientists to pursue creative research ideas across a broad range
https://www.cam.ac.uk/research/news/eight-cambridge-researchers-awarded-eu17-million-in-erc-consolidator-grants
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Monday morning dot plot...
4 months ago
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Interesting study suggesting that nucleus, cytoskeleton, and endomembranes preceded acquisition of mitochondria, during eukaryogenesis
www.nature.com/articles/s41...
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Dated gene duplications elucidate the evolutionary assembly of eukaryotes - Nature
Analysis of eukaryotic gene sequences using a relaxed molecular clock methodology indicate that eukaryotes emerged 3.0–2.25 billion years ago as a result of mitochondrial endosymbiosis with complex ar...
https://www.nature.com/articles/s41586-025-09808-z
4 months ago
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Rapid compensatory evolution within a multiprotein complex preserves telomere integrity
www.science.org/doi/10.1126/...
@levine-lab.bsky.social
very cool work
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Rapid compensatory evolution within a multiprotein complex preserves telomere integrity
Intragenomic conflict with selfish genetic elements spurs adaptive changes in subunits of essential multiprotein complexes. Whether and how these adaptive changes disrupt interactions within such comp...
https://www.science.org/doi/10.1126/science.adv0657?utm_source=sfmc&utm_medium=email&utm_content=alert&utm_campaign=SCIeToc&et_rid=35351378&et_cid=5804810
4 months ago
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reposted by
Ian Henderson
Lars Jansen Lab
4 months ago
A new and fascinating story from
@bencarty.bsky.social
and the group, with crucial help from the teams of
@naltemose.bsky.social
, Simona Giunta, and
@dfachinetti.bsky.social
. Many thanks to all for a fantastic collaboration.
www.nature.com/articles/s41...
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reposted by
Ian Henderson
Vangeli Geshkovski
4 months ago
What a nice coincidence to have Kelly Dawe present his work on karyotype engineering for todays seminar
@thesainsburylab.bsky.social
@johninnescentre.bsky.social
add a skeleton here at some point
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Genetics Society Anniversary Day 25-26th June, Edinburgh
genetics.org.uk/events/anniv...
Society Prize Winners: Hilary Martin, Joe Felsenstein, Richard Durbin, Zam Iqbal Honorary Members: Brian Charlesworth, Deborah Charlesworth, Kay Davies, Paul Nurse, David Sherratt, Veronica van Heyningen
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Anniversary Day 2026 | Genetics Society
We will celebrate the Genetics Society Anniversary Day in Edinburgh, June 25th-26th, 2026. The event will celebrate with talks from our Honorary Members, 2026 Prize and Medal winners, and Summer Stud...
https://genetics.org.uk/events/anniversary-day-2026/
4 months ago
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Chromosome Dynamics 2026 @ Awaji Japan
www.fbs.osaka-u.ac.jp/labs/fukagaw...
4 months ago
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CRISPR-Cas–mediated heritable chromosome fusions in Arabidopsis | Science
www.science.org/doi/10.1126/...
Very nice work from Holger Puchta & colleagues
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CRISPR-Cas–mediated heritable chromosome fusions in Arabidopsis
The genome of Arabidopsis thaliana consists of 10 chromosomes. By inducing CRISPR-Cas–mediated breaks at subcentromeric and subtelomeric sequences, we fused entire chromosome arms, obtaining two eight...
https://www.science.org/doi/10.1126/science.adz8505
4 months ago
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reposted by
Ian Henderson
Genetics Society UK
5 months ago
Nobel Prize winner Svante Pääbo giving the Genetics Society public lecture at
@crick.ac.uk
. Svante is recounting how Neandertals and Denisovans live on in many of us!
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reposted by
Ian Henderson
Genetics Society UK
5 months ago
Congratulations
@hilarycmartin.bsky.social
from
@sangerinstitute.bsky.social
on being awarded the 2026 Balfour Lecture!
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reposted by
Ian Henderson
Genetics Society UK
5 months ago
Congratulations to
@zaminiqbal.bsky.social
from
@milnerevolution.bsky.social
on being awarded the 2026 Mary Lyon Medal!
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reposted by
Ian Henderson
Genetics Society UK
5 months ago
Congratulations to
@vinuesalab.bsky.social
from
@crick.ac.uk
on winning the 2026 JBS Haldane Lecture. Carola will present her JBS Haldane Lecture next year at
@rigb.org
!
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reposted by
Ian Henderson
Genetics Society UK
5 months ago
Congratulations to Joe Felsenstein on being awarded the 2026 Mendel Medal!
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reposted by
Ian Henderson
Genetics Society UK
5 months ago
Congratulations to Richard Durbin on being awarded our Genetics Society Medal!
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FastGA -> ALNview; step into the centromeric matrix!
github.com/thegenemyers
Probably the best dot plot software on the planet...
5 months ago
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reposted by
Ian Henderson
Tanmay Bharat
5 months ago
An Asgard archaeon with internal membrane compartments Brilliant study led by
@fmacleod.bsky.social
and Andriko von Kügelgen. Tight collaboration with
@buzzbaum.bsky.social
and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
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reposted by
Ian Henderson
Julius Brennecke
5 months ago
Some impressions from the rather fabulous
#EMBOmobilegenome
Mobile Genome meeting in Heidelberg Morning walk through the woods, exciting panel discussion, flash talks, lab community, drosophila friends, …
@events.embl.org
The transposon community is going very strong. see you all again in 2027!!
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reposted by
Ian Henderson
Patrick Pausch
5 months ago
After 5 years of waiting, the new
#CRISPR
classification by Makarova et al. is out
@natmicrobiol.nature.com
www.nature.com/articles/s41...
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An updated evolutionary classification of CRISPR–Cas systems including rare variants - Nature Microbiology
An exploration of previously undescribed variants from the long tail of the CRISPR–Cas distribution.
https://www.nature.com/articles/s41564-025-02180-8
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reposted by
Ian Henderson
Jolyon Troscianko
5 months ago
BehaveAI is live! Our biologically inspired video analysis tool sees motion as colour. Track animals or objects, classify their behaviour, and handle complex natural scenes with ease. Semi-supervised annotation, no GPUs required, user-friendly, free & open source. Pre-print
tinyurl.com/BehaveAI
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Ian Henderson
Gregor Mendel Institute of Molecular Plant Biology
5 months ago
Magnus Nordborg of the GMI from the
@oeaw.bsky.social
has received a Synergy Grant from the
@erc.europa.eu
. With Richard Durbin and
@felipekteixeira.bsky.social
, they will investigate how transposable elements shape genome evolution in eukaryotes. Read more:
www.oeaw.ac.at/gmi/news-eve...
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reposted by
Ian Henderson
Jake Harris
5 months ago
Very excited to share our work published in Nature Comms last week! Here we describe a range of cool things that can be done once you have the power to control deposition of H3K4me3…
rdcu.be/eNEf4
A short thread:
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CRISPR targeting of H3K4me3 activates gene expression and unlocks centromere-proximal crossover recombination in Arabidopsis
Nature Communications - Binenbaum et al. demonstrate that precise CRISPR-based targeting of a key chromatin mark (H3K4me3) can switch on genes, boost disease resistance, and unlock meiotic...
https://rdcu.be/eNEf4
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reposted by
Ian Henderson
James Davies
5 months ago
Our latest paper has just been published in Cell!
doi.org/10.1016/j.ce...
We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.
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reposted by
Ian Henderson
Julius Brennecke
5 months ago
great to be at the
#EMBOMobileGenome
meeting in Heidelberg with a wonderful bunch of colleagues, speakers and attendees. this meeting is a good reflection of the excitement and collegiality in the transposon field. kindly sponsored by
@embo.org
add a skeleton here at some point
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‘Epigenetic serum’ makes you wonder !
5 months ago
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reposted by
Ian Henderson
Svetlana Dodonova
5 months ago
Lab’s first paper is out!! We show the first structures of
#Asgard
#chromatin
by
#cryo-EM
🧬❄️ Asgard histones form closed and open hypernucleosomes. Closed are conserved across
#Archaea
, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here:
www.cell.com/molecular-ce...
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reposted by
Ian Henderson
Yasin Dagdas
5 months ago
Really cool work by the
@dodonova-sveta.bsky.social
lab
@embl.org
www.cell.com/molecular-ce...
#archea
#evochromo
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Cryo-EM reveals open and closed Asgard chromatin assemblies
Ranawat et al. show the cryo-EM structures of Asgard archaeal chromatin assemblies, revealing that the histone HHoB assembles into both compact closed and extended open hypernucleosomes. The closed co...
https://www.cell.com/molecular-cell/fulltext/S1097-2765(25)00818-4?rss=yes
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reposted by
Ian Henderson
Rob Klose
6 months ago
We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost!
tinyurl.com/mr3m7bd3
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Ian Henderson
Stephen Tang
6 months ago
Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from? Today, we report the discovery of telomerase homologs in a family of antiviral reverse transcriptases, revealing an unexpected evolutionary origin in bacteria.
doi.org/10.1101/2025...
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reposted by
Ian Henderson
Sternberg Lab
6 months ago
1/10 Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from? Today, we report the discovery of telomerase homologs in a family of antiviral RTs, revealing an unexpected evolutionary origin in bacteria.
www.biorxiv.org/content/10.1...
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Antiviral reverse transcriptases reveal the evolutionary origin of telomerase
Defense-associated reverse transcriptases (DRTs) employ diverse and distinctive mechanisms of cDNA synthesis to protect bacteria against viral infection. However, much of DRT family diversity remains ...
https://www.biorxiv.org/content/10.1101/2025.10.16.682844v1
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Crazy red flesh apple - tastes good too! 🍎
6 months ago
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reposted by
Ian Henderson
Maddy Seale
6 months ago
Out in
@science.org
this week: A new FRET sensor for salicylic acid gives insight into spatial dynamics of pathogen infection
www.science.org/doi/10.1126/...
(1/2)
#PlantScience
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SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance
Salicylic acid (SA) is a key phytohormone that orchestrates immune responses against pathogens, including Pseudomonas syringae bacteria. The timing and extent of SA accumulation are tightly controlled...
https://www.science.org/doi/10.1126/science.adw7650
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reposted by
Ian Henderson
PlantEvolution 🌱🌾
6 months ago
Congrats, Joe Ecker
@salkinstitute.bsky.social
, to receiving the McClintock Prize! Joe has been a visionary leader of the field of genetics and genomics – not only for plants – for decades
www.salk.edu/news-release...
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Ian Henderson
Guillaume Bourque
6 months ago
🚨 New paper alert on telomeres! 🚨 Something different from the group! Thanks to Yuxin, a talented student in the lab, we used long-reads in 75 human trios to study telomeres and their inheritance.
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reposted by
Ian Henderson
Carolyn Bertozzi
6 months ago
My HPLC was definitely overlooked
www.nature.com/articles/d41...
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Prizes must recognize machine contributions to discovery
The future of science will be written by humans and machines together. Awards should reflect that reality.
https://www.nature.com/articles/d41586-025-03217-y
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Ian Henderson
Jstheater
6 months ago
Heading in the correct direction: After success of pilot, Ireland expands basic support payments for artists, making them permanent:
www.irishtimes.com/politics/202...
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Basic income support scheme for artists to be made permanent and opened to new entrants in budget
Negotiations down to the wire, with five big-spending departments yet to agree their budget allocations
https://www.irishtimes.com/politics/2025/10/06/budget-2026-states-basic-income-scheme-for-artists-made-permanent/
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