Happy to announce two-fold news! 1) The SCINKD paper is now published in @molbioevol.bsky.social - doi.org/10.1093/molb... 2) SCINKD [v2.2.4] release has reduced runtimes (about 2x) and the revitalized mode for genomes >5Gb is now live and tested on genomes up to 21Gb! 🐸 github.com/DrPintoThe2n...

@drpintothe2nd.bsky.social et al. present SCINKD as a framework to identify unannotated sex chromosomes and curate diploid genome assemblies from a single individual. 🔗 doi.org/10.1093/molbev/msag067 #evobio #molbio #compbio

Did you know that many organisms delete parts of their genome during development? To know more please join us at the Roscoff meeting on "Mechanistic and Evolutionary Basis of Programmed DNA Elimination" Sep21- 25, 2026. Please share!
cjm.sb-roscoff.fr/en/conferenc...

We have a few spots left on our amazing #ScalableGenomics course. Perfect for anyone doing #genomics of many or difficult genomes, ideal for #PhD students, #postdocs or anyone else who would like to get hands-on experience. Register in the link below! tinyurl.com/scalableGeno... RT appreciated!

Can you believe that until now there were more genomes sequenced for the woolly mammoth than for living African elephants? Today, we bring you the first genomic, continent-scale analyses of 232 high-quality genomes of both species, the savanna and forest elephant. www.nature.com/articles/s41...

Sequencing all complex life in the UK & Ireland could add up to £3bn to the economy over 30 years, a new report finds. Explore the impact of the Darwin Tree of Life Project ⤵️ https://www.sanger.ac.uk/news_item/unlocking-the-value-of-biodiversity-in-the-uk-and-ireland/

Excited to share our latest work in Nature. Applying single-molecule and single-cell DNA sequencing methods, we uncover an extraordinary landscape of somatic mutations in immune checkpoint genes in autoimmune B cells, suggesting that somatic mutations may be key to autoimmunity [1/n] rdcu.be/fdqbr

1/ BRAKER4 hatched! The Earth BioGenome Project is on track to sequence ~1.5M eukaryotic species. Every one needs a structural annotation. No Perl monolith was going to survive that. So we rewrote BRAKER from the ground up. github.com/Gaius-August...

Subscription based academic publishing is a terrible model that has done a lot of harm. I do find the decision by Cancer Research UK understandable, but I like Wellcome's decision not to pay for OA in hybrid journals better.

Is there anyone around Newcastle owning a patch of green where we could collect springtails this Tuesday by any chance? More about the project in @jamesimcc.bsky.social's blog post: sangerinstitute.blog/2026/03/26/s...

Ok, another from my series of weird questions… does anyone know how testes of Psychoda sigma (owl midge) looks like?

Do you plan to analyse lots of genomes? Or few that are large? One or multiple species? Join us for the course on analysing data at scale! (and yes, it will involve a lot of k-mers!). With @katiejenike.bsky.social and others... @sangerinstitute.bsky.social @connectingscience.bsky.social

Does anyone know where will be the next PopGroup? #PGG

I get so frustrated with access to papers. We are slowly getting back to the point when it's easier to physically go to the library and see what they got there...

And this is my favourite figure, nicely illustrating diversity and turnover of oligocentromeric satelites. Look at Carol and Sandra - one invaded the other at least 2x, which I find particularly amusing.

Very proud of @jamesimcc.bsky.social to submit his first PhD paper about evolution of genomes and centromeres in taxa with oligocentromeric organisation. Lots of interesting discoveries including possibly the first reported re-evolution of monocentricity.

🔬 Recruiting a Postdoc!!!! I’m looking for a motivated postdoc to join my lab and work on characterizing the role of a heterochromatin protein involved in a sex-ratio meiotic drive system in Drosophila. If you know someone who might be interested, please share widely!

Excited for this. Teaching popgen is one of my favourite parts of my job and I've wondered about doing an online version of the class for sometime. Teaming up with @jrossibarra.bsky.social to do this is wonderful.

Last two weeks to apply for a senior faculty position at the Tree of Life. Great environment, amazing colleagues and the world's biggest genome engine... Come to join us at the Tree of Life @sangerinstitute.bsky.social sanger.wd103.myworkdayjobs.com/en-US/Wellco...

Join our Tree of Life Programme as a Group Leader in Biodiversity Genomics at the Wellcome Sanger Institute. Lead ambitious, large-scale genomics research to understand life’s diversity on Earth. 🔗 Learn more and apply: sanger.wd103.myworkdayjobs.com/en-US/Wellco... 📅 Closing date: 8 February 2026

The Department of Genetics at the University of Cambridge is seeking a talented Postdoctoral Research Associate to work in the group of Dr Felipe Karam Teixeira (www.gen.cam.ac.uk/research-gro...) ➡️For Further details see the link www.cam.ac.uk/jobs/postdoc...

Open postdoc position at @sangerinstitute.bsky.social Tree of Life to contribute to the Biodiversity Cell Atlas, with a focus on spatial transcriptomics. Apply by January 4 sanger.wd103.myworkdayjobs.com/en-GB/Wellco... Please share with anyone who might be interested!

please share this postdoc job alert! come join the budding Biodiversity Cell Atlas initiative as a postdoc or senior postdoc at @sangerinstitute.bsky.social working closely with @arnausebe.bsky.social and me to make progress on what we cover in this paper www.nature.com/articles/s41...

Are you interested in biodiversity genomics? Fantastic opportunity to join us as a Group Leader at the Tree of Life Programme, @sangerinstitute.bsky.social. 👇 sanger.wd103.myworkdayjobs.com/en-GB/Wellco...

(1/5)Thrilled to announce our paper on #ProjectPsyche is out! 🦋We describe how we’ve generated 1000+ high-quality genomes for European Lepidoptera, providing an unprecedented resource for biodiversity, conservation, and evolutionary research. #Genomics #Biodiversity www.cell.com/trends/ecolo...

I very excited we finally made a new version of #smudgeplot: Skylight. Much faster, improved inference and interface and finally, we have a new experimental features that might be fun toying with. github.com/KamilSJaron/...

final week to apply for @sangerinstitute.bsky.social PhD programme (due Nov 27th) -- free to apply, open to anyone anywhere, and a superb training opportunity for students interested in genomic approaches applied to biodiversity, pathogens, vectors, and of course us pesky humans.

Does anyone have a photo of Charles W. Metz by any chance? He originally isolated the Holo2 line of Bradysia coprophila we still use after more than 100 years after their original capture.

This, except I think we can take leadership in our hands, we don’t need funders to do it for us… All of us can avoid publishing and reviewing for for-profits and it does not have to be too much of a sacrifice (plenty of flashy society/nonprofit journals out there). Be the change.

This looks so good!

Understanding life is starting! Looking forwards to the new following days of talks on biodiversity genomics!

new publication by @amjadkhalaf.bsky.social who mined arthropod reference genome data for hidden microsporidia reads and then did a whole lot of assembling and sleuthing! great job @amjadkhalaf.bsky.social !

Really, really happy that our work on microsporidian genomes is now out in @plosbiology.org! A huge thank you to my coauthors, my supervisors @mblaxter.bsky.social & @marakat.bsky.social, the editors @roliroberts.bsky.social & Joseph Heitman, and the reviewers ❤️ plos.io/48HsAQJ

This is a really interesting story. Microsporidia have genome architecture as no other creatures! Congrats @amjadkhalaf.bsky.social

Preprint Alert! 🦥 We produced complete genomes for 2 Xenarthra and placed them in a mammalian comparative framework. We found that Xenarthra harbour the largest number of retrocopies in mammals! www.biorxiv.org/content/10.1...

What an achievement. I am so excited ATLASea is going strong!

We have a new small GenomeScope based on @jgrg.mstdn.science.ap.brid.gy's pull request. Thanks James! Main new feature --json_report will generate a json formatted list of all the inputs and outputs which will make automatic processing of genomescope results easier. github.com/tbenavi1/gen...

This is getting a bit awkward. Anyone else feels like chipping in?

Last chance to join us next month for the #Biodiversity25 conference. A fantastic set of speakers, mix of talks & focused workshops, and the chance to meet others in the field of biodiversity genomics 🧬 In-person registration closes next Monday 29th September! Registration 🔗: bit.ly/4j3vAZ9

Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life. www.nature.com/articles/s41...

@asn-amnat.bsky.social Did you consider releasing older papers? Asking money for nearly 60 year old papers is a bit... (lacking a good word here) www.journals.uchicago.edu/doi/epdf/10.... Am I the only one weirded by this?!

Our paper Genomic diversity of the African malaria vector Anopheles funestus was published in Science today! It features inversions, selection in action, museum specimens and putative new ecotypes. doi.org/10.1126/scie...

It's that time of the year again... Soon the applications for 12 PhD positions at @sangerinstitute.bsky.social will open. Interested in genomics and thinking about doing a PhD? Join us at Sanger. www.sanger.ac.uk/about/study/...

How many chromosomes can an animal have? In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact. www.cell.com/current-biol...

Mind blowing chromosomal fragmentation of … everything but sex chromosomes in blues. Great piece by @charlottewright.bsky.social at al👏

Rather interesting thread, I always wondered why we don’t peer review preprints more.

You may have missed this #ant poster at #ESEB2025, but be sure not to miss the article just published in #openacess in @nature.com: www.nature.com/articles/s41...

Very nice thread on a big Logan update. This very much looks like the future of querying genomic data.

We had productive 2 days of defining some hard bits of the database as well as figuring out the next steps forward. We will send around notes in the upcoming days. ToS folks are the best, thank you all for taking part and @aruizherrera.bsky.social and @sphaeromeria.bsky.social for organising!

The day 2 of the #TreeOfSex annual workshop started with a great talk by @yannguiguen.bsky.social about B chromosomes and their role in sex determination in fish. Next up, Sònia Garcia is giving an update on the works of the Literature team.