UCL Dept of Aging, Rheumatology & Regenerative Medicine
@arrdept-ucldom.bsky.social
📤 639
📥 1730
📝 105
New department in UCL Division of Medicine - keep an eye out for our research updates!
Wow! What a week.. our
#BSI25
Congress in stats: 3 invited talks 3 selected for abstracts for short talks 1 lunch industry talk and… 14 posters! Not bad for a department less than 1 yr old 👏🏼
23 days ago
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UCL Dept of Aging, Rheumatology & Regenerative Medicine
Diana E Matei
26 days ago
Now more than usual (since I'm considering applying for a sex-differences based fellowship) I enjoyed and appreciated
@ciurtinlab.bsky.social
talk
#BSI25
! We really really need to sex-dissegregate our data!! ♂️♀️
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Pedro Machado MD PhD FRCP
about 2 months ago
First-ever classification criteria for
#haemochromatosis
arthropathy now published! A major step for research & trials in this under-recognised condition. Thanks to the
@eular.org
task force who made this possible - a privilege to work together since 2020!
www.sciencedirect.com/science/arti...
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UCL Dept of Aging, Rheumatology & Regenerative Medicine
Lizzy Rosser
26 days ago
Loving
#BSI25
, especially
@ciurtinlab.bsky.social
and
@emmaschambers.bsky.social
highlighting our paper in
@jem.org
is one of
#ArthritisUK
top research output of ‘25! If you have 5 minutes, give us a vote (number 5) below, sex differences in the immune system:
www.arthritis-uk.org/our-research...
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Research Highlight of the Year
Arthritis UK Research Highlight of the Year: celebrate the outstanding work that’s made a real impact over the past year.
https://www.arthritis-uk.org/our-research/research-we-fund/research-highlight-of-the-year/
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UCL Dept of Aging, Rheumatology & Regenerative Medicine
Diana E Matei
26 days ago
Too many good talks so hard to choose
#BSI25
! For now let's see how our
@arrdept-ucldom.bsky.social
HoD Derek Gilroy presents the great story of
@oliviabracken.bsky.social
's PhD 👏🤩
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Great to see the ARR labs as the background for new borrowers movie!
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about 2 months ago
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UCL Dept of Aging, Rheumatology & Regenerative Medicine
Immune Sex Differences
2 months ago
Some of us may be interested to meet sooner, so
#EESSexDifferences
@EMBLEvents may be of interest. It goes beyond the immune system, but still
www.embl.org/about/info/c...
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Sex differences in health and disease
https://www.embl.org/about/info/course-and-conference-office/events/ees26-07/
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Great to see
@bcellsrosser.bsky.social
perspective in
@natrevrheum.nature.com
highlighted in this editors comment!
www.nature.com/articles/s41...
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The next breakthrough in rheumatology will require prioritizing diversity - Nature Reviews Rheumatology
Progress has been astonishing, but the need for personalized care can only be addressed through a universal focus on diversity and equity in rheumatology research.
https://www.nature.com/articles/s41584-025-01311-z
2 months ago
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UCL Dept of Aging, Rheumatology & Regenerative Medicine
Heather Cross
2 months ago
Amazing talk from Lizzy Rosser
@bcellsrosser.bsky.social
at
@efis-immunology.bsky.social
So cool to hear about how sex determinants influence B cells!
@arrdept-ucldom.bsky.social
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Lizzy Rosser
2 months ago
Congrats
@heather--cross.bsky.social
on a great talk at the EFIS sex difference meeting today!
@arrdept-ucldom.bsky.social
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Great to see
@bcellsrosser.bsky.social
and colleagues taking their science public engagement to
@newscientist.com
live!
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2 months ago
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
George Robinson
2 months ago
Heading up to Manchester this morning to speak in the
@britsocimm.bsky.social
Manchester Immunology Group Seminar Series
@lydiabeckeriii.bsky.social
Looking forward to it!
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Saori Abe
3 months ago
www.nature.com/articles/s41...
Original article📖→
www.nejm.org/doi/10.1056/...
“In vivo CD19 CAR T-cell therapy for refractory systemic lupus erythematosus.” N. Engl. J. Med.
#SLE
#lupus
#CART
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In vivo CAR-T cell engineering in refractory SLE - Nature Reviews Rheumatology
Infused lipid nanoparticles were successfully used to generate CAR-T cells in patients with refractory systemic lupus erythematosus, achieving B cell depletion.
https://www.nature.com/articles/s41584-025-01313-x
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@uclnews.bsky.social
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3 months ago
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Lizzy Rosser
3 months ago
Have been a big fan of the
@theconversation.com
for a while so was a real please to write this article with them. Thank you to
@medresfdn.bsky.social
for suggesting me and please do have a read 👇
theconversation.com/what-is-lupu...
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What is lupus, the condition Selena Gomez is diagnosed with?
The autoimmune disease lupus, which affects mainly women, can have wide-ranging impacts on health and quality of life.
https://theconversation.com/what-is-lupus-the-condition-selena-gomez-is-diagnosed-with-266273
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Fantastic pictures
@georgearobinson.bsky.social
and congratulations again
@ciurtinlab.bsky.social
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3 months ago
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Congratulations 🥳 to Prof Ciurtin
@ciurtinlab.bsky.social
who will deliver the 2025 Lady Estelle Wolfson Lecture in Translational Medicine at the Royal College of Physicians today! Coziana will focus on improving risk stratification and management of cardiovascular risk in young people with lupus.
3 months ago
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
3 months ago
Great session at
#PReS2025
discussing challenges in the transition of care in rheumatology. Session dedicated to the memory
#Dr.JanetMcDonagh
in recognition of her amazing contribution to the field.
@ciurtinlab.bsky.social
@arrdept-ucldom.bsky.social
@versusarthritis.bsky.social
#BANNAR
;
#YourRheum
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Lizzy Rosser
3 months ago
I am so excited to be contributing to the upcoming ‘Medicine at the Crick Event’
@crick.ac.uk
… organised by Prof Vinuesa and Prof Lee.. come and join us for what will be a fantastic discussion…
@arrdept-ucldom.bsky.social
www.crick.ac.uk/whats-on/med...
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Medicine at the Crick | New insights and breakthroughs in autoimmunity
https://www.crick.ac.uk/whats-on/medicine-at-the-crick-new-insights-and-breakthroughs-in-autoimmunity
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We now have over 600 followers! Hello everyone from our new UCL department! Give some of our members a follow when you have a chance (we’ll post the in the thread below!) and stay tuned for our research updates 🧬 🎇 😃
3 months ago
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
George Robinson
3 months ago
Nailed it!
@heather--cross.bsky.social
@ciurtinlab.bsky.social
@arrdept-ucldom.bsky.social
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
George Robinson
3 months ago
Exciting week ahead in Helsinki for
#PReS2025
! 🇫🇮 First up it’s the young investors meeting! Fantastic science and a privilege to be on the organising committee of
#PReSEMERGE
An
@arrdept-ucldom.bsky.social
takeover later for the
#cSLE
session with
@junjie-peng.bsky.social
@heather--cross.bsky.social
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Congrats Nina!
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4 months ago
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Great to see our close collaborator’s paper out now in Annals of the Rheumatic Diseases
@bmj.com
. Read the press release 👇
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4 months ago
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
George Robinson
4 months ago
Loved every minute, thank you
#IUIS2025
and congratulations to everyone on the RS programme!
@iuis-online.bsky.social
@arrdept-ucldom.bsky.social
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
George Robinson
4 months ago
Fantastic week down in Cornwall with the family and my boy. Now off to Vienna for
#IUIS2025
! Excited to meet this amazing international group of early career researchers later today and can’t wait to present tomorrow. See you there!
@iuis-online.bsky.social
@arrdept-ucldom.bsky.social
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Lizzy Rosser
5 months ago
Thanks
@dianaematei.bsky.social
- I loved writing this with Prof Wedderburn in
@natrevrheum.nature.com
on the back of our new departmental launch
@arrdept-ucldom.bsky.social
✨
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
British Society for Immunology
5 months ago
🌟 Got exciting immunology research to share? There’s still time to submit your abstract for BSI Congress!
#BSI25
Present your findings to 1,500+ experts, grow your network, and spark new collaborations that can boost your career. Submit by 3 Sept ➡️
https://bit.ly/3UfF6i5
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Waggoner Lab
5 months ago
Hematopoietic loss of Y chromosome leads to immune inhibitory receptor up-regulation, impairing senescent cell clearance
www.science.org/doi/10.1126/...
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Bethan Goulden
5 months ago
New systematic review of pregnancy associated HLH - 104 pregnancies - commonest cause infections (EBV, CMV, HSV, parvo) - followed by SLE, stills, lymphoma - 4/14 tested has positive genetics - 40% no known cause
onlinelibrary.wiley.com/doi/epdf/10....
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Hemophagocytic Lymphohistiocytosis in Pregnancy: A Systematic Review of Case Reports and Case Series
Aims Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening syndrome caused by excessive immune activation, leading to severe inflammation and multi-organ failure. While adult-onset HL...
https://onlinelibrary.wiley.com/doi/epdf/10.1002/ajh.70013
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Lizzy Rosser
5 months ago
@thelisterinstitute.bsky.social
- a great experience talking about our group’s research for the Lister blog. Working with children and young people is a privilege and I’d ask every translational scientist to ask the question… is your research age inclusive? ✨
lister-institute.org.uk/the-bigger-p...
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The bigger picture: Lizzy Rosser’s quest to understand childhood arthritis and eye disease – Lister Institute
https://lister-institute.org.uk/the-bigger-picture-lizzy-rossers-quest-to-understand-childhood-arthritis-and-eye-disease/
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UCL Dept of Aging, Rheumatology & Regenerative Medicine
8 months ago
www.independent.co.uk/news/health/...
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Simple blood test offers new hope to lupus patients
Up to 69,000 people in the UK have lupus, a chronic autoimmune condition
https://www.independent.co.uk/news/health/lupus-sympotoms-nhs-blood-test-treatment-b2747367.html
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
8 months ago
www.nihr.ac.uk/story/strati...
a big thank you to the lupus specialists and their patients who made this research possible
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https://www.nihr.ac.uk/story/stratify-lupus-personalised-care-patients
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So fantastic to see this work out
@shipam.bsky.social
, with Prof Michael Ehrenstein and Dr Dan McCluskey. This new departmental paper shows the utility of anti-dsDNA IgA2 and IgA2+ B cells as a biomarker for response to Belimumab in SLE. Read in
@cp-cell.bsky.social
journal - Cell Reports Medicine.
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5 months ago
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Discovery Immunology
5 months ago
Writing a paper? Join us tomorrow at 12:00 BST for a free webinar with OUP Publisher Rachel Moriarty & our very own EIC Simon Milling. Essential tips on journal selection, peer review, and maximising impact. Register here:
https://bit.ly/44ARC1p
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Rasmus Iversen
6 months ago
Very happy to share our latest preprint, where we address the relationship between systemic and gut IgA. See link below and details in 🧵. Huge thanks to everyone involved!
www.biorxiv.org/content/10.1...
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Distinct systemic and gut IgA responses to bacteria of the human upper gastrointestinal tract
The mucosa lining the gastrointestinal tract harbors the body's largest population of plasma cells, most of which produce dimeric IgA destined for release into the lumen. In addition, there is systemic production of monomeric IgA circulating in the blood. Little is known about the connection between systemic and mucosal IgA. To address this relationship and to explore antibody responses against the microbiota, we isolated bacteria from duodenal biopsies and assessed antibody reactivity. Systemic IgA showed reactivity to bacteria of the upper gastrointestinal tract with a preference for binding Neisseria species, while duodenal IgA showed broader reactivity. We found limited clonal overlap between gut and bone marrow plasma cells of individual donors, yet a few shared clones specific to bacterial antigens were identified. Despite showing clonal overlap, gut and bone marrow plasma cells have distinct IgA subclass distributions, and they likely depend on B-cell activation at discrete anatomical sites. ### Competing Interest Statement The authors have declared no competing interest. Kristian Gerhard Jebsen Foundation, https://ror.org/021g6tq38, SKGJ-MED-017 Southern and Eastern Norway Regional Health Authority, https://ror.org/02qx2s478, 2022071 University of Oslo, https://ror.org/01xtthb56, WL-IMMUNOLOGY, Scientia Fellows II
https://www.biorxiv.org/content/10.1101/2025.07.01.662496v1
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Rasmus Iversen
9 months ago
I am looking for a PhD candidate to join my lab in Oslo! We are trying to understand the role of antigen-specific B cells in autoimmunity. See details and apply here 👇
2411.webcruiter.no/Main2/Recrui...
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PhD Research Fellowship in Immunology
A 3-year PhD fellowship is available at the Department of Immunology, Oslo University Hospital. The position will be located in the lab of Dr. Rasmus Iversen and will be available from August 2025. Th...
https://2411.webcruiter.no/Main2/Recruit/Public/4945539864?language=en&link_source_id=0&showExpired=False
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Congrats
@heather--cross.bsky.social
, taking the conference circuit by storm!
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6 months ago
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
NEJM.org
6 months ago
A new review discusses the features of oligoarticular, polyarticular, systemic, and psoriatic JIA and enthesitis-related arthritis, as well as advances in treatment for these conditions. Read the full review:
nej.md/4lJMkq4
#MedSky
#PedSky
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Lizzy Rosser
6 months ago
Our lab day out last week in west London by the River… Grateful we are growing due to support from
@medresfdn.bsky.social
#moorfieldeyecharity
&
@thelisterinstitute.bsky.social
. A new generation of leaders in childhood autoimmunity in the making!
@dianaematei.bsky.social
@arrdept-ucldom.bsky.social
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
George Robinson
6 months ago
Can’t wait! Thank you
@iuis-online.bsky.social
and
@britsocimm.bsky.social
!
@arrdept-ucldom.bsky.social
@uclmedsci.bsky.social
@uclpress.bsky.social
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
UCL Great Ormond Street Institute of Child Health
6 months ago
First of its kind study for children with arthritis reveals possible new disease targets. Researchers have been able to see what happens in the inflamed joints of children with arthritis, giving insight into why treatments affect children differently. Read:
www.ucl.ac.uk/news/2025/ju...
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First of its kind study for children with arthritis reveals possible new disease targets
Researchers have been able to see what happens in the inflamed joints of children with arthritis, giving insight into why treatments affect children differently.
https://www.ucl.ac.uk/news/2025/jul/first-its-kind-study-children-arthritis-reveals-possible-new-disease-targets
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So great to see ARR collaborators in science translational medicine this morning -
www.science.org/doi/10.1126/...
. An important movement for
#Paed
Rheum research and tissue biology
#immunosky
@dr-chrissyb.bsky.social
#Wedderburngroup
#Croftgroup
#ChrisMahony
@science.org
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Synovial tissue atlas in juvenile idiopathic arthritis reveals pathogenic niches associated with disease severity
An atlas of the cellular and molecular landscape of the juvenile idiopathic arthritis synovium defines tissue niches associated with disease severity.
https://www.science.org/doi/10.1126/scitranslmed.adt6050
6 months ago
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Lizzy Rosser
6 months ago
#JIA
research on the front cover! Congratulations to
@dr-chrissyb.bsky.social
, Chris Mahony, Prof Wedderburn & CI of MAPJAGProf Croft. This
@science.org
translational medicine study shows the power of studying tissue biology in childhood arthritis. Read it now!
www.science.org/doi/10.1126/...
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Congrats
@mcdonnelllab.bsky.social
on this amazing paper. Resharing in case for those who haven’t had the chance to read it yet!
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6 months ago
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UCL Dept of Aging, Rheumatology & Regenerative Medicine
EFIS_Immunology
6 months ago
📣Call out to
#bcell
enthusiasts!
#EFIS
IL-Study Group European B cell Network is happy to invite you to their Satellite Symposium at the
#IUIS2025
. Don't miss the opportunity to listen to brilliant speakers highlighting the recent advances in
#Bcellbiology
.
@yefis-immunology.bsky.social
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Exciting new position in
#arrdept
alumni
@madhvimenon.bsky.social
lab 🧬
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6 months ago
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Mass Lab
6 months ago
We are SO EXCITED to share our story
@nature.com
: 🧵1/ Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring. This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease. 👉 Read here:
rdcu.be/erD3b
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Kupffer cell programming by maternal obesity triggers fatty liver disease
Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.
https://rdcu.be/erD3b
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
UCL Institute of Education
6 months ago
How can policy support autistic people’s access to employment?
@annaremington.bsky.social
(
@craeioe.bsky.social
) gave evidence to the House of Lords in May emphasising the importance of including autistic people in decision-making on employment and support priorities.
www.ucl.ac.uk/ioe/news/202...
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How can policy support autistic people’s access to employment?
There is a gap between those who want to work and those who can access employment, says Professor Anna Remington, who gave evidence to the House of Lords on supporting employment for autistic people.
https://www.ucl.ac.uk/ioe/news/2025/jun/how-can-policy-support-autistic-peoples-access-employment
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reposted by
UCL Dept of Aging, Rheumatology & Regenerative Medicine
Lizzy Rosser
6 months ago
This was a fantastic celebration yesterday - thanks to the
@thelisterinstitute.bsky.social
and
@arrdept-ucldom.bsky.social
and the wider division of Medicine for all their support 😊
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