Interested in fossils, evo-devo, and how mathematical modeling can help us understand the evolution of developmental processes? In our latest preprint, we uncover an ancestral lateral inhibition mechanism underlying epidermal patterning in liverworts.

Happy to share our new work from my graduate lab: DynamicAtlas, a morphodynamic atlas of Drosophila development! We develop methods for morphological time alignment of live data. Surprisingly, we find that the kinematics of fly morphogenesis are *very* simple. Enjoy! 
www.nature.com/articles/s41...

Wondering about the dynamics during a developmental transition? Check out our preprint “Time-dependent bistability leads to critical slowing down during floral transition in Arabidopsis”, a very exciting collaboration with the Coupland lab @mpipz.bsky.social doi.org/10.64898/202...

excited to announce v2 of my stochastic eco-evo framework is up ! main text now clarifies links w prev werk and points to an emp test of gen corrs result . supp greatly expanded to include worked derivations and further explanation of mathematical foundations !! hope u enjoi ;) tinyurl.com/stecoevo

The variability of evolvability: Properties of dynamic fitness landscapes determine how phenotypic variability evolves https://pubmed.ncbi.nlm.nih.gov/41397131/ #EvoDevo

How do genetic variances and covariances evolve over deep time? This paper unifies quantitative genetics and macroevolution with analytical models for G-matrix evolution on phylogenies, enabling new tests of multivariate trait evolution. academic.oup.com/evlett/artic...

We're looking for a new colleague at Asssoc Prof level! Come join us in the Zoology Department at Stockholm University. A teaching profile in ecology, faunistics and/or physiology is beneficial. Find the full job advertisemnt here: su.varbi.com/en/what:job/...

Kudos to @pdevillemereuil.bsky.social for writing a blog post about our paper published earlier this years in the one and only @peercomjournal.bsky.social ! You want to know how genetically variable plasticity is in your fav system, and what components of reaction norm shape vary the most? Try this!

Very happy to share our 'Evoscape' paper, now published in PNAS ! www.pnas.org/doi/10.1073/...

Great to see this published: Fitting dynamical landscape models to single-cell data, creating interpretable maps of cell decision making & developmental logic Applied to neural tube patterning, we show how morphogen signals reshape landscapes and drive fate decisions www.pnas.org/doi/10.1073/...

1/6 New preprint 🚀 How does the cortex learn to represent things and how they move without reconstructing sensory stimuli? We developed a circuit-centric recurrent predictive learning (RPL) model based on JEPAs. 🔗 doi.org/10.1101/2025... Led by @atenagm.bsky.social @mshalvagal.bsky.social

“Our findings challenge the conventional focus on low-dimensional coding subspaces as a sufficient framework for understanding neural computations, demonstrating that dimensions previously considered task-irrelevant and accounting for little variance can have a critical role in driving behavior.”

One of the most unique aspects of ICTP is our Diploma Programme. Pre-PhD students from the Global South spend 1 year in Trieste to gain knowledge and skills necessary to pursue PhDs worldwide. The 2026-2027 call is now open w/ a February 28 deadline. Please circulate. www.ictp.it/news/2025/11...

Interesting perspective drawing parallels between language models & single‑cell embeddings academic.oup.com/bioinformati...

Next Monday, we welcome @cshambaugh.bsky.social from the University of Oregon in our ROTO Lecture Series who will talk about dialectical biology. Just register via the link and join the talk and discussion at 4pm (CET): rotorub.wordpress.com/roto-lecture... #HPBio #PhilSci #HistSci

📢 The full programme for the 2nd Workshop on Biological Control Systems (WBCS 2025) is out! 🗓️ 19 Nov 2025 | Online across time zones 🔗 Programme & info: biocontrolseminars.org/workshop-2025

Is it possible to estimate rates of phenotypic evolution that are independent of the time interval covered by the data? In theory, yes — even when the data are incomplete and biased. But in practice? Not so much. Amazing work by @vildebruhn.bsky.social

How can we organize current theoretical approaches for developmental biology - from information to dynamical systems & GRNs - into a common framework? We propose to think along Marr's 3 levels: computational problem, algorithm, implementation Check out our review: arxiv.org/abs/2510.24536

What is the origin of diversity in allometric laws scaling across species? Check our new paper led by Andrea Tabi where we propose a new theory of metabolic scaling grounded in thermodynamics and stochastic fluctuations at the cellular level. www.biorxiv.org/content/10.1...

🚨 Come join us @sheffielduni.bsky.social for a PhD on the evolution and development of feathers and flight! 🐣🔬 This project is supervised by @matt-towers.bsky.social & @alexgfletcher.bsky.social, and I'm excited to be involved as a project advisor. Please share! www.findaphd.com/phds/project... 🧪

A personal favorite, long time in the making. Adelina and David (@dduneau.bsky.social) were instrumental in getting this done. doi.org/10.1186/s129...

One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential. www.biorxiv.org/content/10.1...

Polygenic risk scores obtained for a single individual over a range of commercially available tests. FFS

I’m excited to announce the launch of my lab at EPFL in Jan 2026 🎉. We’ll combine evolution & synthetic biology to study and (re)engineer bacterial communication. I’m recruiting PhD students to start in the first semester of 2026. Apply via EPFL PhD programs by Nov 1 drive.google.com/file/d/1cm-t...

New review out! With students in my lab, we explore how population size shapes speciation—from drift in small populations to selection in large ones. Do small or large populations speciate faster? The answer is more nuanced than you might think. esj-journals.onlinelibrary.wiley.com/doi/full/10....

Interpretable gene network inference with nonlinear causality https://www.biorxiv.org/content/10.1101/2025.09.28.678927v1

I'm excited to share with you all a conference I'm planning Oct. 10-12: Dialectical Biology Today: Legacies of Richard Lewontin. It will be hybrid in Toronto and on zoom, so please join us however you can! Register for zoom link here: ihpst.utoronto.ca/events/diale...

Now out in @nature.com: Our study discovering a neural circuit in Drosophila that predictively inhibits proprioceptor axons during voluntary leg movements, such as walking and grooming. www.nature.com/articles/s41...

⏳ Only 2 weeks left to apply to our PhD in evolutionary prediction!

(1/14) I’m happy and proud to introduce: SpinePy – a framework to detect the "spine" of gastruloids and measure biological and physical signals in a local dynamic 3D coordinate system. www.biorxiv.org/content/10.1...

Parallel but distinct adaptive routes in the budding and fission yeasts after 10,000 generations of experimental evolution https://www.biorxiv.org/content/10.1101/2025.09.11.675703v1

A central finding is that, even if we could measure pairwise interactions up to a certain precision, strong indirect effects can make our efforts useless: at high collectivity, pairwise interactions no longer inform about community coexistence www.biorxiv.org/content/10.1...

Mutations in the circadian cycle drive adaptive plasticity in cyanobacteria in #PNAS from Raúl Fernández-López with @pabnik.bsky.social @amazeld.bsky.social www.pnas.org/doi/10.1073/...

DeepAtlas: a tool for effective manifold learning https://www.biorxiv.org/content/10.1101/2025.08.26.672474v1

Can a virus help uncover Turing patterns in nature? In this @commsbio.nature.com paper, researchers show how the tulip breaking virus triggers the expression of a pigment that can display a broad range of (observable) stripe patterns @philipcball.bsky.social biorxiv.org/content/10.1...

🚨New PhD research published in PNAS!🚨 Combining fossils and lab experiments, we found that simple changes in tooth #development explain 6 million years of molar #evolution in #voles 🐭🦷 Shoutout to my coauthors @cnrs.fr @helsinki.fi @gtk-fi.bsky.social! www.pnas.org/doi/10.1073/... #FossilFriday

🚨 We're hiring! PhD position in Evolutionary Systems Biology at Stockholm University & SciLifeLab 🎓 Focus: evolution, development, computational & mathematical modeling, prediction 📍 Stockholm, Sweden 🕒 4 years, fully-funded 🔍 Details: su.varbi.com/en/what:job/... Please share!

! Evolution of developmental bias explains divergent patterns of phenotypic evolution in two nematode clades www.pnas.org/doi/10.1073/...

Developmental bias explains the evolutionary trend towards simple leaf shapes https://www.biorxiv.org/content/10.1101/2025.08.17.670617v1

How do regulatory genes control alternative life histories? We have an open PhD position to answer this question using functional genomics in Atlantic salmon. Apply by October 15th through www.jobbnorge.no/en/available... Please share widely! 🧬🦑🖥️

What is emergence? This is one of the most central ingredients of complexity, and a challenging one to formalize. Here's a paper by @seanmcarroll.bsky.social & Achyth Parola that attempts to classify different forms of emergence. @manlius.bsky.social @sfiscience.bsky.social arxiv.org/pdf/2410.15468

Adaptive radiation along ecological and morphological lines of least resistance in Cyprinodon pupfishes https://www.biorxiv.org/content/10.1101/2025.08.13.670168v1

Join us on the 26/9 in Lund for a symposium about #evolution #stemcells #development #EvoDevo and #plasticity

Latest on Waddington Landscapes: Computational methods to fit dynamical landscapes directly to single cell data Applied to neural tube patterning shows morphogen-signalling landscapes can be linearly interpolated Connects interpretable landscape models with data www.biorxiv.org/content/10.1...

My first solo author paper is now available in early view at Methods in Ecology and Evolution! I develop a covariance reaction norm (CRN) model for estimating continuous, multivariate, and nonlinear environmental effects on G and P matrices. besjournals.onlinelibrary.wiley.com/doi/10.1111/...

*PhD position* 🦉 Would you like to do a PhD with Indo-Pacific birds and evolutionary genomics? Join us in Stockholm: <deadline> 05 September 2025, 23:59 PhD student in Evolution of Indo-Pacific birds recruit.visma.com/spa/public/a...

I am really excited to see this article on basic experimental design principles published. Definitely will be mandatory reading for incoming graduate students in my lab. Maggie Wagner who led this article did an amazing job with the illustrations of basic principles www.nature.com/articles/s41...

Constrained variation in the internal architecture of avian wing bones https://www.biorxiv.org/content/10.1101/2025.08.07.669070v1

Our paper benchmarking foundation models for perturbation effect prediction is finally published 🎉🥳🎉 www.nature.com/articles/s41... We show that none of the available* models outperform simple linear baselines. Since the original preprint, we added more methods, metrics, and prettier figures! 🧵

Introducing five concepts from dynamical systems to decode developmental regulatory mechanisms, have a read! @perez-carrasco.bsky.social‬ @roederlab.bsky.social @mpipz.bsky.social This effort started in a morphogenesis meeting @kitp-ucsb.bsky.social‬ in 2023. journals.biologists.com/dev/article/...