Do you want to know about #ALS #MND genetics? Are you affected directly or indirectly by ALS MND or working as a scientist or clinician in this area? I was honoured to give the Hawking Lecture this year and it's now freely available to view. www.mndassociation.org/professional...

New research reveals what people with #MND/#ALS need when deciding on genetic testing: clear info, implications for family & tailored support.📃 This data can help inform decision aids to assist people when thinking about genetic testing. Read more🔗 ukmndri.org/2025/12/03/g...

🚨 Final Call for the £7.5m (~$10m) Longitude Prize on ALS. Don’t miss your chance to make a real difference for those living with #ALS (the most common form of #MND). Submit your application by 15:00 GMT (10:00 AM EST) tomorrow! Apply here: bit.ly/4nyp6nq

⏰1 week to go! Entries to the £7.5M (~$10M) Longitude Prize on ALS are closing next week – submit your application before Wednesday 3rd December 2025. Your expertise could make the difference. 🔗Learn more and apply today: bit.ly/4nyp6nq

@ohenews.bsky.social estimates that eradicating ALS could deliver $143B+ in value over 10 years. The potential global value is huge. #ALS and #MND remain underfunded and breakthroughs are urgently needed. Full report: lnkd.in/e3-DMaiB Learn more about the Prize bit.ly/4nyp6nq

🚨 Only 2 weeks left to apply! The £7.5M (~$10M) Longitude Prize on ALS is closing soon – submit your application before 3 December 2025 and don’t miss your chance to make a real difference. 🔗 To learn more about the Prize, click here: bit.ly/4nyp6nq

People with #ALS #MND with respiratory compromise should be offered COVID immunization by their GPs. united2endmnd.org/2025/11/14/c...

Drug development is a complex and costly process. By using medicines approved for other conditions, we can overcome barriers in drug development. Read our blog explaining why we believe repurposed drugs could help us find new treatments for #MND/#ALS. ukmndri.org/2025/11/13/r...

Yesterday, we attended @mndoddie5.bsky.social's Discovery Network Showcase 2025. Researchers, clinicians, industry partners, and people affected by #MND/#ALS discussed how the network can drive forward progress in better understanding MND and the development of new treatments.

Our Co-Director, Prof. @ammaralchalabi.bsky.social, gave a fantastic talk yesterday, hosted by @mndassoc.bsky.social, on #MND/#ALS genetics, why they matter and how discoveries are shaping new treatments. Thank you to everyone who joined in person & online! #MNDresearch #genetics

We had the pleasure of catching up with Dr Brian Dickie MBE (@bd365.bsky.social), Chief Scientist at the @mndassoc.bsky.social, the principal funder of the £7.5M Longitude Prize on ALS. 📖 Read the full Q&A here: bit.ly/3KTi1Ap

Join us at the #ASHG25 Annual Meeting in Boston, starting today! Visit us at Booth 46, we’d love to meet you and discuss how the ~$10M Longitude Prize on ALS is harnessing #AI to transform the future of neurodegenerative disease treatment. @challengeworks.bsky.social @geneticssociety.bsky.social

We must find an effective treatment for #ALS #MND @ukmndri.bsky.social BBC News - Former England captain Moody reveals MND diagnosis www.bbc.com/sport/rugby-...

⏰ 2 months to go until applications close for the £7.5 million Longitude Prize on ALS. You could help transform treatment for neurodegenerative diseases like hashtag #ALS, the most common form of motor neurone disease ( #MND ). Learn more: bit.ly/4mlzSg5

Connect with us at #NealsMtg ! We are thrilled to be joining the NEALS meeting once again in person this coming week. For anyone impacted by ALS virtual registration is free. Cheers to NEALS for such an open policy. See more at https://meeting.neals.org/#NealsMtg. #EndtheLegacy #NEALS

This is a landmark paper showing a predictive test for #ALS #MND up to 40 years before onset and able to predict age of onset. Huge implications www.nature.com/articles/s41...

🌍 Be part of the global effort to tackle #ALS. The £7.5m (~$10m) #LongitudePrizeOnALS is searching for innovators in #AI, #data, #biotech, and #neurology. 🧠 Meet the teams already registered, and find out how you can partner with them below. 🔗https://bit.ly/4mdHxxX

🧠 The @ukmndri.bsky.social is an #MND powerhouse, accelerating progress towards new treatments and, ultimately, a cure. Read their article about how the #LongitudePrizeOnALS could be a game-changer for drug discovery in neurodegenerative diseases. 🔗 bit.ly/40Tmmsh @ammaralchalabi.bsky.social

Postdoc Research Assistant in Dr Arpan Mehta’s lab at University of Dundee, using CRISPR screens in iPSC-derived motor neurons to study ALS mechanisms. Closing date: 4th August www.dementiaresearcher.nihr.ac.uk/job/postdoc-...

“MND is one of the most scientifically and biologically challenging diseases to tackle. That said, no mountain is insurmountable…” Dr. Mike Rogers (@mndassoc.bsky.social) shares why the #LongitudePrizeOnALS is key to creating new opportunities for #ALS & #MND 📰 longevity.technology/news/climbin...

Tagging 🧪 🧬🖥️

New research has examined how disrupted sleep patterns may signal the early stages of #MND / #ALS or FTD, providing clues to earlier detection. Read more ⬇️ 🔗 ukmndri.org/2025/07/16/r... This post is part of our Research Snapshot series, powered by Readable Research at @sheffielduni.bsky.social

Researchers reveal that structural variants disrupting the 3D genome can drive diseases like cancer by altering gene expression. by Sreenivasan VKA, Yumiceba V and Spielmann M in Nat Rev Genet #MedSky 👉 get more here 📖 read the article:

⏰ Reminder: Our first Welcome Webinar is tomorrow, Tuesday 9th of July at 09:00 BST. 💻 Register below to learn everything you need to know about the #LongitudePrizeOnALS, including how to apply, how the Prize works, and what support is available.

Research Fellow vacancy at UCL MND Centre. Join Prof Andrea Malaspina’s team to study immune responses and neoantigens in ALS using proteomics and cell phenotyping. Closing date: 20th July www.dementiaresearcher.nihr.ac.uk/job/research...

🧠 As the principal funder, the @mndassoc.bsky.social has been instrumental in bringing the #LongitudePrizeOnALS to life. We were joined by Dr Usman Khan last week, who spoke on the power of cross-specialism collaboration. Learn more about the Prize: bit.ly/4kD3tSh #AIforGood #MND #ALS

Want to learn more about the £7.5M #LongitudePrizeOnALS? Join one of our welcome webinars to find out how the Prize works and how to get involved. Register here: 📅 9 July, 09:00 BST: bit.ly/4nzJuWA 📅 10 July, 17:00 BST: bit.ly/3Tl4u5u #AIForGood #MND #ALS

Check out this article from Dr Brian Dickie (@mndassoc.bsky.social), exploring how #AI and quality data can transform treatment progress—and how the £7.5M #LongitudePrizeonALS aims to support #innovation through global collaboration. 🧠 Read here: bit.ly/4nqi4lN #ALS #MND

Apply now for the NIHR Senior Investigator award! £15K per year for 4 years to support top researchers shaping the future of health and social care in the UK. @nihr.bsky.social www.dementiaresearcher.nihr.ac.uk/funding/nihr...

What a week for the #LongitudePrizeOnALS 🧠 Thank you to everyone who made it possible! 🎥 Watch the segment on BBC News here: bit.ly/4eoGyaR This is just the beginning. Entries close 3 Dec → Learn more on our website: bit.ly/4kD3tSh @trisdyson.bsky.social @ammaralchalabi.bsky.social #AIforGood

Join Dr Arpan Mehta's lab at MRC PPU, Dundee, for a 12-month postdoc using CRISPR screens to explore ALS in iPSC-derived motor neurons. Closing date: 18th July www.dementiaresearcher.nihr.ac.uk/job/postdoc-...

Today is #MNDAwarenessDay, a moment to highlight the hidden realities of living with #MND. Our translational research projects aim to find treatments for MND through a national, coordinated approach. 👉 Discover more: ukmndri.org/2025/06/20/f...

Professor Sir Simon Wessely is a world-renowned academic psychiatrist and epidemiologist and has been awarded this GBE in recognition of his distinguished position as 'the pre-eminent psychiatrist of his generation in the UK.' ⬇️ www.kcl.ac.uk/news/profess...

We are delighted to announce that Professor Sir Simon Wessely has been awarded a Knight Grand Cross of the Order of the British Empire (GBE) in this year's King’s 2025 Birthday Honours. 🎉 🧵⬇️ @kingsioppn.bsky.social

Join a leading dementia research team as a Clinical Research Fellow at UCL. Work on trials for novel Alzheimer’s and FTD therapies. Closing date: 2nd July www.dementiaresearcher.nihr.ac.uk/job/clinical...

Back from Torino where I was able to hear hundreds of smart young ALS investigators from all corners of Europe. (This pic was taken at the very last session on a Friday afternoon. They stayed.) 1/

Day 3

Read about our latest findings from the @MNDRegister showcased at the @ENCALS Meeting 2025.🌍 Findings ranged from a new #MND/#ALS incidence and prevalence analysis to clinical characteristics and outcomes. Read more here⬇️ ukmndri.org/2025/06/04/m...

EVERY ALS MND scientific conference needs to allow for those with ALS MND who want to attend to be there in person or virtually. It is simply wrong to exclude them.

We are pleased to announce that the @ucl Queen Square Motor Neuron Disease Centre Sixth Hybrid #ALS/#MND International Symposium in Partnership will be held on Friday 5/9/25. The theme is Translating Targets to Therapies. To register, click below⬇️ www.eventbrite.co.uk/e/ucl-queen-...

This week, we launched our brand new and redesigned website for the @MNDRegister.🗺️ But why is it so important? Find out how this vital resource is helping researchers understand who is affected by #MND/#ALS and why. 📖Read more below. ukmndri.org/2025/05/28/m...

Our paper on the theoretical properties of SNP heritability in admixed populations is out in Genetics: academic.oup.com/genetics/adv... with @jinguohuang.bsky.social, @nicole-kleman.bsky.social , Saonli Basu, and Mark Shriver

So lucky to have the best lab. Will miss @kittybmurphy.bsky.social so much 😢❤️ but excited to see her future successes in ancient genome research!

📄The UK MND Clinical Studies Group has released an official statement in response to the MIROCALS study results. Find out what it means for future research into #MND / #ALS 🔗 ukmndri.org/2025/05/15/uk-mnd-clinical-studies-group-issues-statement-on-mirocals-trial-findings/

The #MIROCALS study has now been assessed by the UK MND Clinical Studies Group. Their consensus statement can be found here: ukmndri.org/2025/05/15/u... #ALS #MND #clinicaltrials @ukmndri.bsky.social @mndassoc.bsky.social @mndoddie5.bsky.social @mndscotland.bsky.social

We may be closer to treating motor neuron disease (or #ALS) thanks to a new clinical trial involving Sheffield University scientists. We've a primer 🧵 from the MIROCALS trial, published in @thelancet.bsky.social, below, or jump to the story on our website 👇 1/5 www.sheffield.ac.uk/news/landmar...

Our paper describing the results of the MIROCALS trial of low-dose interleukin-2 in #ALS #MND is out in the Lancet @thelancet.bsky.social Open access Read it here: www.thelancet.com/journals/lan...

ALL ALS scientific conferences should think like this... pactalscongress.com/nina-buscomb...

If your condition is getting worse very quickly, your health and social care team may recommend you complete the Fast-track Pathway Tool. This must be completed by a doctor or a registered health professional. #MND #KennedysDisease Find out more www.mndassociation.org/chc