Sign up now to a special symposium in memory of Euan MacDonald MBE, hosted by the Euan MacDonald Centre for #MND Research. 📍 Edinburgh 📅 8–9 October 🔬 Cutting-edge MND/ALS research 🌍 Public sessions on SpeakUnique & Euan’s Guide euanmacdonaldcentre.org/euan-macdonald-tribute-symposium-2025

Fatigue affects nearly all people with #MND/#ALS, yet it's often overlooked. A new UK-wide study reveals how fatigue evolves, its severity, and its link to other symptoms. This can inform future research and care. 🔗Read more👇 ukmndri.org/2025/09/04/f...

One of Raya Therapeutic's compounds has been selected for our EXPERTS-ALS programme. A pioneering initiative designed to fast-track promising treatments for #ALS/#MND. Read more about the story and why it is so significant below👇 ukmndri.org/2025/09/03/r...

🧠 The @ukmndri.bsky.social is an #MND powerhouse, accelerating progress towards new treatments and, ultimately, a cure. Read their article about how the #LongitudePrizeOnALS could be a game-changer for drug discovery in neurodegenerative diseases. 🔗 bit.ly/40Tmmsh @ammaralchalabi.bsky.social

A new study has identified a blood-based biomarker panel that can detect #ALS up to a decade before symptoms appear. Using machine learning and protein profiling, researchers found 33 proteins that distinguish ALS from other conditions. ukmndri.org/2025/08/28/2...

A simple finger-prick blood test could transform how #MND/#ALS is monitored. New research from @ucl.ac.uk shows that NfL levels from capillary samples match those from traditional blood draws, suggesting a more convenient and less invasive way to sample blood. ukmndri.org/2025/08/20/f...

The first treatment for a form of #MND/#ALS has been approved in the UK. #Tofersen is authorised for SOD1 MND, demonstrating the potential of gene-targeted therapies. UKMNDRI RI partners @sheffielduni.bsky.social & @kingsioppn.bsky.social contributed to the trials. ukmndri.org/2025/07/31/f...

We're thrilled to see the first research nurse recruited to the @mndassoc.bsky.social’s new #MND Research Nurse Network. The network will be essential in providing the support and expertise needed to create equitable access to trials for all🔎 Read more 🔗 www.mndassociation.org/media/latest...

New research has examined how disrupted sleep patterns may signal the early stages of #MND / #ALS or FTD, providing clues to earlier detection. Read more ⬇️ 🔗 ukmndri.org/2025/07/16/r... This post is part of our Research Snapshot series, powered by Readable Research at @sheffielduni.bsky.social

Today is #MNDAwarenessDay, a moment to highlight the hidden realities of living with #MND. Our translational research projects aim to find treatments for MND through a national, coordinated approach. 👉 Discover more: ukmndri.org/2025/06/20/f...

Read about our latest findings from the @MNDRegister showcased at the @ENCALS Meeting 2025.🌍 Findings ranged from a new #MND/#ALS incidence and prevalence analysis to clinical characteristics and outcomes. Read more here⬇️ ukmndri.org/2025/06/04/m...

We are pleased to announce that the @ucl Queen Square Motor Neuron Disease Centre Sixth Hybrid #ALS/#MND International Symposium in Partnership will be held on Friday 5/9/25. The theme is Translating Targets to Therapies. To register, click below⬇️ www.eventbrite.co.uk/e/ucl-queen-...

This week, we launched our brand new and redesigned website for the @MNDRegister.🗺️ But why is it so important? Find out how this vital resource is helping researchers understand who is affected by #MND/#ALS and why. 📖Read more below. ukmndri.org/2025/05/28/m...

🚨We’ve launched a new home for the @MNDRegister! The MND Register is the first comprehensive source of information about people with #MND/#ALS. We hope that by counting every person with MND, we can learn more about the disease. Learn more below🔗 mndregister.ac.uk

🔬RESEARCH SNAPSHOT📢 A recent study has uncovered that a breakdown in communication between structures in nerve cells can disrupt their ability to produce energy. This could potentially lead to new treatment targets for #MND/#ALS 🔎Read more👇 ukmndri.org/2025/05/20/r...

📄The UK MND Clinical Studies Group has released an official statement in response to the MIROCALS study results. Find out what it means for future research into #MND / #ALS 🔗 ukmndri.org/2025/05/15/uk-mnd-clinical-studies-group-issues-statement-on-mirocals-trial-findings/

We’re working to shape the UK’s research environment for MND to accelerate the search for a cure.🔬 Our goals: ✅ Accelerate drug discovery ✅ Better understand MND ✅ Support research participation ✅ Coordinate a national strategy Learn more 👉 ukmndri.org/ourstory

Introducing our new Research snapshot series. Where we highlight the latest #MND studies reported by Readable Research @sheffielduni.bsky.social 🔬 First up: a look at toxic proteins in a mouse model of C9orf72-related MND and what it tells us about future treatments. ukmndri.org/2025/04/14/r...

📢 Calling all researchers! Thinking of applying for our Discovery Network or Advancing Treatments Award? Don’t miss our webinar on 15 April at 12pm. Hear more about the awards, ask questions & gain insights on how to sharpen your application Here’s the link to join 👇 us06web.zoom.us/webinar/regi...

The international #LighthouseII trial testing HIV drug Triumeq for #MND has been halted early after an interim analysis showed no survival benefit. A full analysis will follow. Thank you to all who took part. Read more ⬇ ukmndri.org/2025/04/07/l...

Following a successful first year of their Research Strategy, @mndoddie5.bsky.social has launched the 2025 Advancing Treatments Award & Discovery Network Award. For details & to apply, visit their Funding Opportunities page! #MND www.myname5doddie.co.uk/research/fun...

A huge thank you to everyone who took part in and supported the Darby Rimmer Foundation’s #MarchOfTheDayII🙌 Your incredible efforts help fund vital #MND research and support those affected by the disease. Thank you to all who sponsored us.

🎥Watch this short film highlighting the important progress in #MND research from @uclbrainscience.bsky.social and @crick.ac.uk With a $100m investment and patient safety trials expected for 2026, it offers real hope for new future treatments. Watch below👇 vimeo.com/1055246074?r...

Last week, MPs from the APPG on #MND visited our labs at @kingscollegelondon.bsky.social to explore groundbreaking research and discuss the future of MND research. Political support is vital to driving progress towards new and effective treatments. ukmndri.org/2025/02/18/m...

Many people with #MND are asking about ellorarxine. How are new drugs approved, and what does the evidence say about this research and drug? 🔬 We break down the drug development process and how we’re working to speed it up. ukmndri.org/2025/02/07/a...

🚨 Exciting news! We've just launched the first Supporter Edition of our newsletter!🚀 If you want to stay up to date with the latest #MND research and breakthroughs from the us, make sure to sign up now and never miss an update. ukmndri.org/sign-up-for-...

🚨We're working to accelerate the development of new treatments for #ALS. Read more about how our pioneering study, EXPERTS-ALS, aims to rapidly screen potential drugs for evidence that they can slow progression in people with ALS. 🔗 Find out more 👇 ukmndri.org/2025/01/29/s...

It was great to attend last week's @mndoddie5.bsky.social parliamentary reception at the @houseofcommons.parliament.uk. Our co-director, @ammaralchalabi.bsky.social, gave a talk on #MND, and it was great to meet APPG on MND chair @ianbyrnemp.bsky.social to discuss how we can accelerate research.

Our researchers at the University of Sheffield have launched a new digital platform to improve access to research for people living with #MND. TiM-R aims to overcome barriers by improving research access and accelerating the search for a cure.✍ Read more below👇 ukmndri.org/2024/12/12/s...

Exciting news! We've recruited the 1st patient for our #ALS Biomarkers Study. This project aims to better understand why #MND happens, what influences its progression, and how we might slow or stop it. We're thrilled to begin this vital work and discover new insights!🔬

Tris Dyson, @ammaralchalabi.bsky.social and Jeffrey Rostein presenting the Longitude Prize on ALS. The Longitude Prize will give access to large datasets and bring together experts in AI and ALS to identify and validate drug targets and pathways relevant to the disease progression. #alsmndsymp

We are delighted to announce that Dr Alfredo Iacoangeli was awarded the esteemed Paulo Gontijo Award at the opening of the Montreal 32nd International #ALS/#MND Symposium. This global accolade celebrates excellence in MND research. Read more here: ukmndri.org/2024/12/07/u...

We're in Montreal, attending the #alsmndsymp - where we'll be learning about the latest updates in #ALS/#MND research from across the world.🌎 Are you attending and fancy a chat? Come and say "Salut!" to us at Booth 15th. See you there!🤝

RESEARCH NEWS🚨 #Tofersen, a drug shown to slow progression of #SOD1-MND, is closer to approval in the UK. NICE has reconsidered its evaluation process after calls from the #MND community, offering renewed hope. Read more here: ukmndri.org/2024/11/21/b...

Sign up for our newsletter! Stay up-to-date with the latest in #MND research.🧬 Our newsletter brings you updates on our vital research projects and the latest in breaking news - straight to your inbox.📩 Sign up here: ukmndri.org/sign-up-for-...