Spatial gene expression maps in vertebrate limbs display conserved and regenerative species-specific features within connective tissue https://www.biorxiv.org/content/10.64898/2025.12.15.694399v1

A bit late but a paper from our lab has been published! Human fingertip regeneration is a fact, it happens in children and adults (not only in children as it has been long believed). We describe here the regenerative phases and analyse the proteome of wound exudates. www.nature.com/articles/s41...

Si se corta una planaria en trozos, cada uno de ellos es capaz de regenerar un organismo completo: un pedazo de la cola regenerará una nueva cabeza. El estudio de estos gusanos planos encierra la esperanza de poder imitarlo para regenerar nuestros órganos

Can't believe my postdoc paper is finally out. Christmas came early this year, holy moly 🎄 Molecular basis for de novo thymus regeneration in a vertebrate, the axolotl | Science Immunology www.science.org/doi/10.1126/...

💚🦴 Fluorescence Friday: Halloween edition! 🎃 This glowing mouse embryo skeleton is serving serious spooky vibes 👻 Who knew bone development could look this eerie and elegant? 💀 Image by @martinestermann.bsky.social #FluorescenceFriday #SpookyScience

Places available in our online courses this autumn: @embo.org Project Management (17-19.09), Negotiation for Scientists (18-19.09), Lab Leadership for Postdocs (07-09.10) and for Group Leaders (04-06.11) + Self-Leadership (14-16.10). Register now: www.embolableadership.org/our-courses/ #EMBOLabLead

A preprint co-authored by MDI Bio Lab Ph.D. student @damgargar.bsky.social (@murawalalab.bsky.social) is already turning heads! The study was recently highlighted by @prelights.bsky.social, a journal featuring noteworthy preprints of particular interest to the biological community. 🧪 🤝

We're grateful to have our #preprint featured in @prelights.bsky.social. Thank you @dhanuush.bsky.social for selecting it! Check it out! 🤩 @mdibiolab.bsky.social @murawalalab.bsky.social

Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury. www.nature.com/articles/s41... A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka. 🧵1/14

Delighted to see this work from my lab published today, where we identify a population of ETV-1 positive glutamatergic neurons that are activated in the brain in response to a distant injury. www.nature.com/articles/s41...

Happy Easter to all who celebrate from Chonk and the axolotls!

The @embo.org practical course on #lightsheet #microscopy is back! Join us in #Dresden for 2 weeks with #your #samples, try the complete line-up of #lightsheet microscopes, tackle big data image analysis, sample prep, OA hardware & much more Apply now! Repost 🙏 meetings.embo.org/event/25-lsm

It has been known for a long time that if the starting point of limb regeneration is at the hand level or close to the shoulder, it would take about the same time to regenerate. Puzzling right? Check out this preprint from our lab to know more about it: www.biorxiv.org/content/10.1...

Embryonic induction of fate is a core concept in developmental biology. But, cells can also modify the physical state of surrounding tissues a process we call 'actuation'. I reviewed with @mayorlab.bsky.social 3 excellent papers that show how actuation and feedback can drive changes in the embryo.

🚨Latin American Workshop Series🚨 The team from @bethcimini.bsky.social‘s lab at @broadinstitute.org and the Center for Open Bioimage Analysis will host three free online image analysis workshops for LATAM ... in SPANISH🇪🇸 and PORTUGUESE🇧🇷!!!🎉🎊 broad.io/latam_worksh... Deadline: April 23rd, 2025

The essential role of connective-tissue cells during axolotl limb regeneration https://www.biorxiv.org/content/10.1101/2025.03.30.645595v1

Pre-print alert: This is our latest work on limb regeneration. We found that connective-tissue (CT) cells are necessary for this process by using a combinatorial approach of #spatial transcriptomics and an #ablation system for the first time in the #axolotl! 👇🧵1/6 www.biorxiv.org/content/10.1...

Registration for the ISRB Madison Conference is now open. Early bird registration ends June 15th so don't delay. We also have a pre-meeting workshop for trainees. Hope to see you all in Madison!

Registrations are open for the EMBO Practical course on light sheet microscopy! Great opportunity to learn all kinds of light-sheet, as well as image postprocessing from the experts themselves. meetings.embo.org/event/25-lsm

Peer review completed within 7 days! Paying peer reviewers! Yes, it's possible. Fast & Fair peer review by @biologyopen.bsky.social More innovation from @biologists.bsky.social Details here: www.biorxiv.org/content/10.1...

This is a cross section of an axolotl's zeugopod by @damgargar.bsky.social, shows the #nuclei (blue), muscles (yellow), and connective tissue (red). A #zeugopod is the middle segment of a vertebrate limb, allowing movements like flexion, rotation & extension. #microscopymonday #standwithscience 🧪 🤝

This #microscopymonday image by Katelyn White is an HCR-ISH on an axolotl neural tube — a technique that amplifies the signal of #RNAtranscripts in cells and tissues (blue nuclei & magenta Shh gene). The Shh gene plays a crucial role in embryonic development. 🧪🤝 👩‍🔬 #standwithscience

The first original research paper from my lab is now out in @biorxivpreprint.bsky.social! www.biorxiv.org/content/10.1... Tracheal development is an amazing model to study morphogenesis. There are great works out there that show how this tissue elongates, interconnects, and forms branches (1/n)

Science thrives because of our dedicated researchers, students, supporters, and community members. At MDI Bio Lab, we believe in the power of discovery, education, and collaboration. Thank you for #standupforscience2025, believing in science, and being part of our community! #standwithscience 🧪 🤝

At @science.org today, an important new way we can make major headway into immunologic and infectious diseases. Sequencing the lymphocyte B and T cell receptors and A.I. to accurately make the diagnosis! www.science.org/doi/10.1126/science.adp2407 A seminal study by @anshulkundaje.bsky.social et al

The Society for Developmental Biology has released a statement on how the Abrupt Dismissal of NIH and NSF Staff Undermines Government Efficiency. bit.ly/3X9VEKd

Registration for LSFM at @mdibl-lmf.bsky.social 6/1-6/7 is now open! This is an amazing academic environment, and is unique that all the major vendors will be there and students are ENCOURAGED to bring their own samples! mdibl.org/course/lsfm-...

We are grateful to @isrbio.bsky.social for their support of the ReBilD course @mdibiolab.bsky.social. mdibl.org/course/rebil... Please RT. 🙌

My team @naturecomms.bsky.social is looking for a new editor! We need someone to help handle all of the awesome #stemcell and #devbio papers we're getting. DM me if you're interested or have questions about the role or interview process. springernature.wd3.myworkdayjobs.com/en-US/Spring...

New experimental feature: timelapse for #mesoSPIM! Because why not? You can now image live specimen, such as developing organisms. Checkout this SW version at: github.com/mesoSPIM/mes... and let us know how it works for you. Be brave!

And the newt genome ms is finally out! www.cell.com/cell-genomic... Thanks @andrassimon.bsky.social @niche-leigh.bsky.social labs for an amazing collab, and specially Tom Brown for great assembly skills. @dcgenomecenter.bsky.social @crtd-tud.bsky.social @mpicbg.bsky.social @poldresden.bsky.social

for those interested in time-lapse imaging and quantitative 4D tracking of live mouse (or other) embryos, here is our detailed protocol, with all the computational pipelines available in one portable drive, ready to roll. Martin Dominguez's brilliance here! star-protocols.cell.com/protocols/3936

To mark the 40th year since the homeobox discovery, we've commissioned a series of articles from leaders in the field demonstrating the impact of the discovery on different disciplines. Check out the full collection: https://journals.biologists.com/dev/collection/10249/40-years-of-the-homeobox

Do you need a salamander phylogeny? You're in luck! We put together the largest salamander phylogeny to date based on molecular markers and used more fossil calibrations than any other currently available trees. 765 salamander species! Check it out! www.sciencedirect.com/science/arti...

Come to Tokyo March 2026 for the limb conference! Honored to be sharing the keynote space with Cliff Tabin and Ken Poss.

Wow, killifish almost became a toy in the 1960s! The video is wild. boingboing.net/2024/12/16/h...