🌍It was a great honor to host #BriardoLlorente from the #AustralianGenomeFoundry at the #ParisBiofoundry! We exchanged insights, experiences and collaboration opportunities, and toured the Sorbonne Foundry to showcase our cutting-edge facilities. @arccoesb.bsky.social @parisbiofoundry.bsky.social

Design of a Modular Inducible Circuit for Pulsatile Population Control of Engineered Bacteria doi.org/10.1101/2025...

🚀 The #DNAfoundry at @parisbiofoundry.bsky.social is now fully assembled! A new hub for #highthroughput DNA design, #assembly & #sequencing, accelerating #SyntheticBiology research.🔬✨ @cnrs.fr @sorbonne-universite.fr @genopole.bsky.social @institutcurie.bsky.social @inrae-france.bsky.social

📢 The SC-DNA 2025 registration deadline is extended to May 31st! Register now to attend the Storage & Computing with DNA 2025 conference (June 19-21, @sorbonne-universite.fr)! 📷 🔗 premc.org/storage-comp... #DNADataStorage #ComputingWithDNA #SCDNA2025

Introducing SAVEMONEY, AKA ‘Simple Algorithm for Very Efficient Multiplexing of Oxford Nanopore Experiments for You’ A new tool offering a faster, cheaper computational approach to democratise whole-plasmid sequencing. buff.ly/ov7YumB

💾 🧬 Arrange your summer travel now to these great conferences: tinyurl.com/597uthcu • Storage & Computing with DNA, June 19-21, Paris • New Trends in DNA-Based Data Storage, June 3-6, Prague • Symposium on Chemistry of Nucleic Acid Components, June 8-13, Český Krumlov

Phage satellites are now known to be very diverse, numerous and ancient. They pose many evolutionary, ecological and mechanistic questions. Lots of fun in perspective! Great pleasure to write this review to show it, with @jrpenades.bsky.social @dbikard.bsky.social Kim Seed & John Chen.

Interested in photosynthetic organisms? Looking for a space to focus on research and kick-start your journey as a group leader? We’d love for you to join us. We offer an incredibly competitive package—on par with about 2 ERC grants for 8 years—and a collaborative environment unlike anywhere else 1/2

Rubisco enzyme is responsible for capturing CO2 from the atmosphere, crucial for photosynthesis. Recent research has mapped mutant Rubisco molecules which could revolutionize plant CO2 assimilation & adapt to future climates buff.ly/OLYpwtX v @innovativegenomics.bsky.social #PlantScience #Science

Timed batch inputs unlock significantly higher yields for enzymatic cascades www.researchsquare.com/article/rs-5...

💬 “It’s important to recognise the importance of miniaturisation in #genomics for the future." Two automation specialists from the Earlham Institute recently worked with the application development team at @sptlabtech.bsky.social on the development of firefly®. @drkarimgharbi.bsky.social

🚨 Deadline Extension for Storage and Computing with DNA 2025 🚨 🔹 New abstract submission deadline: March 21, 2025 🔹 New registration deadline: April 21, 2025 premc.org/storage-comp... @dnadatastorage.bsky.social @biomemory.com @sorbonne-universite.fr @slemaire75.bsky.social @pcrozet.bsky.social

Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus | Science www.science.org/doi/10.1126/...

Yesterday, we had the pleasure at @leibnizinm.bsky.social to hear Dr Lemaire from the @parisbiofoundry.bsky.social on how DNA can be used for data storage 🧪 and the amazing capabilities of the biofoindry! Such a joy 🙂 Here my sketchnotes✏️

"Chlorella Vulgaris is a freshwater microalga rich in protein, lipids, carbohydrates, vitamins, and minerals. Unlike conventional agriculture, which requires extensive land and water resources, it can be cultivated sustainably with a minimal footprint. www.sciencedaily.com/releases/202...

📢 Big news at the Paris Biofoundry! We’ve welcomed the Echo 650T Series Acoustic Liquid Handler from #BeckmanCoulter . With contact-free acoustic transfers down to 2.5 nL, this game-changing tool enhances assay miniaturization and boosts efficiency for #DNAassembly, #DrugDiscovery and more!

📢 Big news at the Paris Biofoundry! We’ve just received the Orbitrap Ascend Tribrid Mass Spectrometer (MultiOmics model). A game-changer for #Proteomics, #Metabolomics & #MultiOmics research, it’s here to empower innovation in synthetic biology & biotherapies. @thermofishersci.bsky.social

Exciting opportunity! Max Planck Institute for Terrestrial Microbiology is looking for a Head of the DNA-Biofoundry MaxGENESYS. Join us in vibrant #Marburg - apply by 15 February 2025. #ScienceJobs #SyntheticBiology #Biofoundry @maxplanck.de

Unlike our cells, each of which becomes terminally differentiated (eventually), Volvox cells retain the ability to nimbly shift functions. But also unlike single-celled relatives like Chlamydomonas, they don't have to undergo major changes to go from somatic (body) to gonidial (reproductive) forms.

Cell-Free Synthesis System: An Accessible Platform from Biosensing to Biomanufacturing doi.org/10.1016/j.mi...

Randomizing the human genome by engineering recombination between repeat elements | Science www.science.org/doi/10.1126/...

Cell-Free PURE System: Evolution and Achievements www.sciencedirect.com/science/arti... #CellFree #CFPS #SynBio

🦠 When Bacteria Go Gel! 🦠 Researchers discovered that in polymer-rich environments, like mucus in cystic fibrosis, bacteria form tangled “cables”- a living Jell-O effect! read more: www.synbiobeta.com/read/when-ba... #ScienceFacts #Microbiology #Caltech

Out today in Separation & Purification Technology journal. Sebastian Overmans, PhD, Himanshu Mishra, and Adair Gallo Jr. show how to functionalize microparticles and use them as adsorbants for terpene extraction from microbial cultures. Illustration Heno Hwang www.sciencedirect.com/science/arti...

A genetically encoded fluorescent biosensor for visualization of acetyl-CoA in live cells: Cell Chemical Biology www.cell.com/cell-chemica...

A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms. https://buff.ly/40nMuKL

LIFE FINDS A WAY!!! www.sciencedirect.com/science/arti...

A collection of amazing Rubisco papers and preprints this week. Here's another! www.biorxiv.org/content/10.1...

Cell-free protein synthesis as a method to rapidly screen machine learning-directed protease variants doi.org/10.1101/2025...

#CNRSinnovation💡 La nouvelle lettre innovation du CNRS est sortie ! Laboratoires communs, start-up, brevets, événements... Retrouvez tous les mois les dernières actualités de la #valorisation et de l'#innovation au CNRS. 👉 www.cnrs.fr/fr/la-lettre...

Rubisco is slow across the tree of life doi.org/10.1101/2025...

Automated adjustment of metabolic niches enables the control of natural and engineered microbial co-cultures doi.org/10.1016/j.ti...

It's a good week for rubisco enthusiasts - very cool preprint from Ron Milo lab www.biorxiv.org/content/10.1... impressive screening of +250 genes spanning available diversity of rubisco, this then used to predict activities of 68,000 known sequences revealing role of phylogeny and habitat

Synthetic photorespiratory bypass improves rice productivity by enhancing photosynthesis and nitrogen uptake (Guoxin Chen, Yanni Li, Kaining Jin, Jiabei Gao, Suting Wu, Xuean Cui, Chuanzao Mao, Xinyou Yin, Tiegang Lu, Zhiguo Zhang) https://doi.org/10.1093/plcell/koaf015 #PlantScience

Plastoquinone redox status influences carboxysome integrity via a RpaA- and ROS-dependent regulatory network https://www.biorxiv.org/content/10.1101/2025.01.24.634715v1

Self-driving laboratories, advanced immunotherapies and five more technologies to watch in 2025! www.nature.com/articles/d41...

Bacterial-MERFISH combines 1000-fold volumetric expansion with multiplexed fluorescence in situ hybridization, enabling high-throughput, spatially resolved profiling of thousands of operons within individual bacteria. www.science.org/doi/10.1126/... #NBThighlight

🚨 New preprint! We know that plasmids are associated with very variable fitness costs in their different bacterial hosts. But, what is the contribution of each of the plasmid-genes in these host-specific effects? Study led by @jorgesastred.bsky.social, @sanmillan.bsky.social and myself! 1/14

Brilliant work by Takeharu Nagai and team: Creating coveted bioluminescence colors for simultaneous multi-color bioimaging www.science.org/doi/10.1126/...

📰 Excited to see the @parisbiofoundry.bsky.social featured in @lemonde.fr! The article highlights our work tackling antibiotic resistance, led by @vincent-libis.bsky.social. 🔬 Discover how we’re using synthetic biology to uncover new antibiotics from soil microbes: www.lemonde.fr/sciences/art...

Hashing the message with cells by @francolab.bsky.social lab www.nature.com/articles/s41...

Mutation of negative regulatory gene 𝘊𝘌𝘏𝘊𝟣 encoding an FBXO3 protein results in normoxic expression of 𝘏𝘠𝘋𝘈 genes in 𝘊𝘩𝘭𝘢𝘮𝘺𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘳𝘦𝘪𝘯𝘩𝘢𝘳𝘥𝘵𝘪𝘪 www.biorxiv.org/content/10.1...

Working prototype of a heating/cooling modular algae photobioreactor with built in bubbler, multispectral sensor, and grow light. No custom PCB's. All off the shelf parts. Simple arduino code. Open source. This one's for @kylelauersen.bsky.social. I love making lab hardware. #scisky

Mark your calendar 🗓️, arrange your travel ✈️, and we’ll see you in Paris! Join us for Storage and Computing with DNA 2025 from the 19th – 21st of June: premc.org/storage-comp... @dnadatastorage.bsky.social @biomemory.com @sorbonne-universite.fr

A lunar lander will embark on a journey to the Moon, carrying tokens and a significant piece of historical data. This data, securely encoded in synthetic DNA by @dnadatastorage.bsky.social Alliance member Iridia, Inc. is encapsulated within a monument symbolizing humanity's achievements!

DNA Data Storage Alliance members CATALOG and Imagene along with Plasmidsaurus and Asimov Press have delivered the first commercially available book encoded into DNA! @dnadatastorage.bsky.social @plasmidsaurus.bsky.social

Interesting overview of latest in commercialization of gene edited crops www.nature.com/articles/s41... #plantsci

The @houseoflords.parliament.uk Science and Technology Committee has released a report on #engineeringbiology, proposing a set of well-timed and robust recommendations on policies and investment needed by the UK’s #lifescience industry to deliver health, environmental, and economic benefits. 🧬 1/4