We have developed a new workflow to map in 3D at single-cell resolution whole human organs. Prof. Rong Fan (Yale) mapped out immune cell populations in the vicinity of ovarian precancerous lesions in healthy women and found no enrichment. More here: www.biorxiv.org/content/10.1...

Peritumoral macrophages recruit eosinophils to promote antitumor immune responses in breast cancer | PNAS www.pnas.org/doi/abs/10.1... congratulations to Joe Saglimbeni and Boris Reizis lab!

The National Institutes of Health’s budget, and structure, would be preserved under a Senate bill for the 2026 fiscal year.

This just in… FY’26 Bill Highlights: National Institutes of Health: $48.7 billion for biomedical investments in research. Cancer: $7.4 billion for the National Cancer Institute, including $28 million for the Childhood Cancer STAR Act. www.statnews.com/2025/07/31/n...

Cautious optimistic! Was there a streamed hearing? What’s the source?

Nowosad Lab will be recruiting postdocs soon. Reach out if you are interested!

#MicrobiotaPower via #Exercise! Phelps, Meisel &co show @cp-cell.bsky.social that exercise drives formate from microbiota that in turns activates NRF2 in CD8 T cells driving STAT1/IRF8 programs that potentiate immune checkpoint inhibitor efficacy against #melanoma! dlvr.it/TLqLW7

We are hiring! Please help spread the words. Thank you!

Abstract deadline extended to Monday, June 30! And travel grants are still available to student and post-doc members. Don't miss out - REPOST to share the info with others.

Last week was big for IL-12 engineering @cytokinesociety.bsky.social : Membrane-IL12 adjuvant mRNA vaccine polarizes pre-effector T cells for optimized tumor control url:https://rupress.org/jem/article-abstract/222/9/e20241454/278038/Membrane-IL12-adjuvant-mRNA-vaccine-polarizes-pre

Happy to be part of @kingofpathogens.bsky.social study showing mRNAs encoding IL-12 enhance CD8 T cell responses to co-administered HA mRNA vaccines. Study led by Emily Aunins and Anthony Phan from the Hunter lab @upenn.edu www.science.org/doi/10.1126/...

188 PhD/graduate fellowships from private foundations, federal agencies and international organizations. Database can be downloaded here: research.jhu.edu/rdt/funding-...

A few quotes I love from this article about writing: "There’s no such thing as thinking", "Writing. Is. Thinking.", "Without writing there is no thinking and no real opportunity for exchange in the marketplace of ideas."

#MustRead. For #TumorImminologyLovers & more, check this fantastic review @ostunilab.bsky.social &co @cp-trendsimmuno.bsky.social all about #IL1 from #macrophages & pathogenic #inflammation in #cancer. #ScienceMatters dlvr.it/TJslPb

#TickTock⏰! Udeehardt, LaiGuan NG, @drusqui.bsky.social &co show @nature.com that skin #neutrophils produce in a circadian manner extracellular matrix potentiating skin barrier & that after injury they create TGFb-dependent rings of matrix shielding pathogens & foreign molecules!

Beautiful work by Ed Thorp’s team. We did a journal club on this paper and learned a lot about the crosstalk between resident macrophages and cardiomyocytes through thromoxane signaling and efferocytosis. www.cell.com/immunity/abs...

Happy to share our new study on the functional reprogramming of neutrophils in the brain tumor microenvironment by hypoxia-driven lactylation @theaacr.bsky.social @wistar.org @moffittnews.bsky.social

Congratulations, Jie, Xiaoqin, and the team! Beautiful work!

Just noticed that the study section meeting was rescheduled to 4/10/2025 🤞

Neutrophil extracellular traps promote pre-metastatic niche formation in the omentum by expanding innate-like B cells that express IL-10: Cancer Cell www.cell.com/cancer-cell/...

This is the first movement from Sen. Fetterman, please fill out immediately if you have been impacted. Please circulate Penn, Pitt, PSU, Temple etc @cbartman.bsky.social

U.S. early-career researchers struggling amid chaos www.science.org/content/arti... #research #science

My R01 was scheduled to be reviewed tomorrow, but the meeting (TIR) got cancelled just now with a yet-to-be-determined future date. 😥

Gooooo Erik!

Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2 www.cell.com/cell/abstrac...

March 7. Stand Up For Science. Rallies in DC and nationwide. 🧪 Please visit the website and spread the word. www.standupforscience2025.org

This is outstanding. All academic scientists should be required to watch this.

Zooming out vs. Zooming in

Such an exciting time for IL27 @cytokinesociety.bsky.social @kingofpathogens.bsky.social

IL27

Last update of our databases for the year. Download them here: 493 early-career funding opportunities: research.jhu.edu/rdt/funding-... 313 postdoc fellowships: research.jhu.edu/rdt/funding-... 189 PhD fellowships: research.jhu.edu/rdt/funding-...

Happy Holidays from the Zhang lab! Lots of things to celebrate since the last lab event: new students, postdocs, and grants as well as the new paper that many of you have seen. What a year! Hoping for an even better 2025!

How chemotherapy has an impact on #ovariancancer and the potential for maintaining its efficacy with immunotherapy. Still early stage research but potentially very promising. #cansky #ovcasky #medsky #TCells healthcare-in-europe.com/en/news/chem...

Liver metabolizes high fructose corn syrup to fructose, which leads to increase production of LPC lipids that promote tumor growth. #Glycotime www.nature.com/articles/s41...

Very grateful for the generous support from the V Foundation and my previous postdoc, Taito Miyamoto, who developed this project! @thevfoundation.bsky.social

Intersectional genetic cell targeting

A great way to start my BlueSky journey! Very excited to share the first research article from my lab! #MyeloidCell #OvarianCancer #IL27 #Omentum #Ascites @jexpmed.bsky.social