Excited to share the Ovarian Cancer Research Syndicate line-up of speakers for the fall. Please share. We have amazing trainees presenting and the latest from leaders in the field. @powelldrescher.bsky.social @srocf.bsky.social @pennmedcso.bsky.social @penncancer.bsky.social

Another inspiring and successful DoD OCA workshop where science, collaboration, and camaraderie come together to push research and care forward.

A friend shared this article: www.nytimes.com/2025/09/14/m... The public needs to know!

Thank you to the #CanaryFoundation for hosting our ovarian pre-cancer atlas team meeting this week. We are excited to start working on Atlas 2.0!

Great trip to the UK for the British Gynecologic Cancer Society meeting and a visit to @ox.ac.uk Oxford University. Thank you to Drs. Manchanda and Ahmed for the invites. Beautiful and historic places.

Beautiful morning in London. Excited to attend the 2025 British Gyn Cancer Society #BGCS meeting.

If you are opposed to vaccinating your kids and don't think measles is a serious disease - please read this. Your decisions affect not only your family - but everyone they interact with. www.nytimes.com/2025/06/22/u...

Delighted and honored to receive a Pershing Square grant to support our work in ovarian cancer and to attend the award ceremony in NYC! t.co/m6QnLqjuQD @pennmedicine.bsky.social @penncancer.bsky.social @upenn.bsky.social @billackman.fanpeeps.com

It was an absolute honor and delight to deliver the 2nd Annual Erin Rothfuss lecture Johns Hopkins today. Getting to meet the family made it extra special. Thank you to Amanda Fader for the invitation and the opportunity to connect with so many Hopkins colleagues!

New @nature.com An ingenious way to track DNA replication patterns at the single-cell level that leads to cell heterogeneity and daughter cells that can potentially give rise to cancer www.nature.com/articles/s41...

NIH budget: $ 48b Musk wealth: $351b Both are mostly funded by your tax dollars But only one might save your life . . . . Sources: www.nih.gov/about-nih/wh... Search results: elon musk net worth g.co/kgs/6c8YEuB @standupforscience.bsky.social

Now online in Cancer Discovery: Generation of a Biliary Tract Cancer Cell Line Atlas Identifies Molecular Subtypes and Therapeutic Targets - by Vindhya Vijay, Negin Karisani, Gad Getz, Nabeel Bardeesy, and colleagues doi.org/10.1158/2159...

mTORC1 is activated when cells are fed with amino acids. New preprint with @robzonculab.bsky.social led by Rachel Jansen shows how the massive "CastiGATOR" complex is formed when arginine-free CASTOR1 binds to the GATOR2 complex to antagonize mTORC1 starved cells. tinyurl.com/yr6en6f4

We have updated our database of funding opportunities for Early-Career Researchers (private foundations, federal, international) We have 456 entries, for which we provide $ amount, deadline, eligibility criteria, etc. Download this massive database here for free: research.jhu.edu/rdt/funding-...

Our first NIH ovarian cancer SPORE team mtg with our @hopkinsmedicine.bsky.social partners since our successful renewal! Thanks to our EAB/IAB members for their time & insights. Great day of science! Thanks to Yelena for all the invaluable help. @deniswirtz.bsky.social @penncancer.bsky.social

The speed of light visualized on a cosmic scale. Credit: Dr James O'Donoghue

Does this include CRUK-NIH Cancer Grand Challenges (RFA currently open)? @cancergrand.bsky.social www.nature.com/articles/d41...

Thanks for the opportunity @onclive.bsky.social!

Online now in Cancer Discovery concurrent with Victor Velculescu's #AACR25 presentation on next-gen liquid biopsies for early detection: Detection of Brain Cancer Using Genome-Wide Cell-Free DNA Fragmentomes doi.org/10.1158/2159...#AACR25

Periodic reminder this is FDA-approved for men as well as women up to age 45! It covers 9 strains of HPV so even if you’ve been exposed to some, it can protect you from others. It works on strains that cause cervical, vaginal, vulvar, anal, throat and back of mouth cancer. Low-key medical miracle.

Another great #AACR meeting! Great energy, incredible science, and wonderful opportunity to connect with former trainees, colleagues, and collaborators. @ocacademy.bsky.social

Wonderful to celebrate Dr. Patrick Sung from @utsanantonio.bsky.social as the Basser Global Prize Awardee and keynote speaker at the 2025 Basser Center for BRCA Symposium!

Impact of BRCA mutations, age, surgical indication & hormone status on the molecular phenotype of the human Fallopian tube ft. Dalia Omran, Euihye Jung (@Penn_OCRC), Natalie Shih, Lauren Schwartz (@pennpathlabmed.bsky.social) & @rdrapkin8-penn.bsky.social (@PennOBGYN) www.nature.com/articles/s41...

Surprising findings of BRCA mutations on the Fallopian tubes. Result of a tremendous team effort with @shenhui1986.bsky.social @vainstitute.bsky.social, Chuck Drescher @fredhutch.bsky.social, and Jarrod Marto @danafarber.bsky.social. @pennmedcso.bsky.social www.nature.com/articles/s41...

New article out in The Dispatch thedispatch.com/article/nih-... 1/n

Celebrating first-author papers with mugs from #ScienceGrit (sciencegrit.com). Congrats to Matt Knarr and Pamela Rojas de Santiago!

Excellent excellent excellent from Princeton president and constitutional/ political theorist Chris Eisgruber. There's been far too little of this kind of thing; here's hoping others follow his good example. www.theatlantic.com/ideas/archiv...

The impact of COVID and the death of public health. What will happen when the next pandemic hits? Another great article by #DrSidMukherjee Covid’s Deadliest Effect Took Five Years to Appear www.nytimes.com/2025/03/10/o...

apnews.com/young-scient...  Young scientists see career pathways vanish as schools adapt to federal funding cuts.

"From cutting research funding to attacking free speech, the Trump administration has declared war on colleges. The United States is going through its own cultural revolution." x.com/i/status/190...

Aspirin may enhance the immune response against cancer metastasis in mice, according to research published in Nature. The authors suggest that the findings could aid the development of effective anti-metastatic immunotherapies. https://go.nature.com/3F3GWOB 🧪

Current mood

From Forbes magazine: “NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report“ www.forbes.com/sites/michae...

The House of Representatives just passed a CR that includes devastating cuts to the Congressionally Directed Medical Research Program (CDMRP) – 57% cut. It is absolutely critical that we reach out to our Senators now and urge them NOT to include these cuts. Call them!

Holy. Fucking. Shit.

A special issue on #WomensHealth in #ScienceAdvances highlights a growing wave of research focusing on women’s unique biological and psychological experiences. Learn more: scim.ag/3R59fPe (THREAD 🧵)

Genome editing success for the first time in nine patients with alpha-1 antitrypsin deficiency, a heritable disease which can cause cirrhosis and emphysema, affecting ~100,000 Americans, which is similar to the prevalence of sickle cell disease www.nytimes.com/2025/03/10/h...

Who funds biomedical research? @nature.com www.nature.com/articles/d41...

This is an excellent video that explains NIH funding and indirect costs. Super important to understand this. It is critical funding: youtu.be/NtqK8SyxFMc?...

Congratulations to Pamela Rojas de Santiago on her paper in @Nature_NPJ Precision Oncology showing LINE-1 ORF1p expression in clear cell ovarian cancer precursors (endometriosis) and detection in patient samples. 🎉 rdcu.be/ecv6k @powelldrescher.bsky.social @tinaswish.bsky.social @srocf.bsky.social

Standing up for Science at Philly City Hall! Who would have thought we'd have to do this?!? Science serves society! Science is diverse! Science saves lives! America is great because of science! "If you stand for nothing, you will fall for anything!" #StandUpforScience2025

Rally for Science!

Standing up for Science at Philly City Hall!!

Super important!

New preprint from the lab - Selective depletion of cancer cells with extrachromosomal DNA via lentiviral infection www.biorxiv.org/content/10.1...

Neutrophil extracellular traps promote pre-metastatic niche formation in the omentum by expanding innate-like B cells that express IL-10: Cancer Cell www.cell.com/cancer-cell/...

Did you know cancer cells can be electrically active, just like neurons? This electrical activity plays a key role in tumor progression. Excited to share my first postdoc paper at @crick.ac.uk (and first paper from Leanne Li lab), published in @natureportfolio.nature.com!

🎯Breaking News Enzyme used in meiosis makes the cut in vitro News www.nature.com/articles/d41... Paper 1 doi.org/10.1038/s415... Paper 2 doi.org/10.1038/s415... Paper 3 doi.org/10.1038/s415...

Outstanding thread on university endowments! I would encourage all faculty anywhere to read this.