OCA ECI alum Jogender Tushir-Singh's lab shows that, unlike in macaques, human TIGIT isn't cleaved into a soluble decoy. This may explain why TIGIT antibodies have struggled in clinical trials. Read all about it below: www.sciencedirect.com/science/arti...

ECI Mohammed Dwidar presenting at OCMF

Another inspiring and successful DoD OCA workshop where science, collaboration, and camaraderie come together to push research and care forward.

September is Ovarian Cancer Awareness Month!

MD/PhD student Mihai Dumbrava from our #LabFunEpi presenting his work about an epigenetic persister cell signature using single using single cell ATAC+RNA profiling of HGSC patient samples at the AACR Ovarian cancer meeting in Denver CO.

Congratulations to DOD OCA ECI Denarda Dangaj Laniti's lab on publication revealing TIL:myeloid crosstalk as a key driver and therapeutic target in BRCA-dependent immune rewiring of recurrent ovarian cancer. www.cell.com/cancer-cell/...

Congratulations to DOD OCA alum Jogender Tushir-Singh on recent publication showing how a human-specific mutation in FasL makes us more susceptible to cancer. www.nature.com/articles/s41...

Hear from OCRP leaders in this video series on how the Ovarian Cancer Academy supports researchers in making ovarian cancer the focus of their scientific careers and accelerating progress in the field: www.youtube.com/watch?v=rC2G... www.youtube.com/watch?v=ogO4... www.youtube.com/watch?v=DwWV...

Congratulations to OCA alumni Drs. Dmitriy Zamarin and Juan Cubillos-Ruiz, and Deputy Dean @rdrapkin8-penn.bsky.social, on being Pershing Square Foundation Ovarian Cancer Challenge Grant recipients! pershingsquarephilanthropies.org/news/the-per...

Another great #AACR meeting! Great energy, incredible science, and wonderful opportunity to connect with former trainees, colleagues, and collaborators. @ocacademy.bsky.social

www.gilead.com/stories/adva... Features DOD OCA Alum Katherine Chiappinelli’s Lab!

The POTEE-ntial is huge! More amazing work by our ECI Marion Curtis, uncovering TTLL8, POTEE, & PKMYT1 as new tumor antigens. pmc.ncbi.nlm.nih.gov/articles/PMC...

Amazing work done by our ECI Marion Curtis. What was once 'cryptic' in OC is now clear, hidden peptides may hold the key to powerful immune responses! www.science.org/doi/10.1126/...

Ovarian Cancer Midwest Focus conference: Flash Talk presentation first prize to my student @yiwenxie.bsky.social! Very sharp!

The Ovarian Cancer Midwest Focus (OCMF) conference at Sanford Research in Sioux Falls, South Dakota was a total blast. The keynote speakers (Don Cleveland and Denise Montell) were amazing. The flash talks by the trainees were fascinating....and Casino Night was super fun. @pennmedicine.bsky.social