I love phagocytosis- the most ancient form of immunity (estimated at 1 billion yrs old!). Lucky to geek out with all the other macrophage and neutrophil geeks at beautiful Keble college, Oxford.

New clues to understand #HealthyAging from @yalemed.bsky.social studying longevity in nature. #SenNet www.science.org/doi/epdf/10....

Sharing on behalf of Dr. Florian Krammer for those interested - his podcast is great! Episode 0 of my new podcast viroLOGICAL is online. This first episode is a little longer and gives a general overview of viruses and viral diseases. Find it on Apple, Spotify, and Podigee: virological.podigee.io

Learning lots about #lung autoimmunity as a contributor to severe #asthma from Dr Manali Mukherjee from #TheFirestone. Great reminder that blood is not always the right place to sample for autoimmunity -sputum can be a much more informative marker.

Both chambers of Congress have now passed the FY26 minibus with NIH provisions. The President will sign. (1) $48.7 billion for NIH (2) Full IDC recovery (3) No more multi-year funding (4) No NIH reorganization, maintaining the current IC structure.

Thank you to Bob McDonald for hosting me on @CBCRadioCanada to discuss our work @yaleschoolofmed.bsky.social on what leads to variation in common cold virus infections and how we tackled this using nasal organoids. Listen here: www.cbc.ca/listen/live-...

Glad to join today in teaching #CyTOF for Yale's Computational Proteomics course directed by Dr. Maria Rodriguez Martinez. Multidimensional single cell immune profiling for #HIPC takes a team including Dr. Adam Tanguay and Dr. Ashish Shelar.

My most recent manuscript is available from @pnas.org . We describe a population of inflammatory cytokine MIF responsive T cells and their importance in Rheumatoid Arthritis pathogenesis.

Solo markers were interesting but combining gene SNPs and plasma metabolite data showed predictions for severe #COVID. That's why we study the whole #SystemsImmunology #BigScience #Teamwork

Dr. Leila Denmark co-developed the pertussis (whooping cough) vaccine. World's oldest practicing pediatrician until she retired at age 103 (after 73 yrs). At the time of her death at age 114 & 60 days, she was the 5th-oldest validated living person in the world & 3rd-oldest in the US. #WomenInSTEM

I am excited to share our new paper @JExpMed led by our one and only #Alejandra_Aroca

Representative Betty McCollum (D-MN, 4th) met with AAI Councilors Gwendalyn Randolph, Steve Jameson, and CPA Chair Lauren Ehrlich! They had a great conversation about how crucial robust funding is for NIH. Thank you for the support! #AAIadvocacy

AAI Councilors Donna Farber, Avery August, and Laurie Harrington had a wonderful meeting with staff from Rep. Josh Riley’s (D-NY, 19th) office, discussing the importance of NIH funding and science-based policy. #AAIadvocacy

The NIH grant cuts in 2025 www.nytimes.com/interactive/...

Super excited for the upcoming #cellbio2025 @ascbiology.bsky.social @embo.org meeting in Philadelphia! Check out the Special President's session on "The Rising Tide of Science Denial" on Saturday at 1pm!

We are proud to feature 2025 RCCN Pilot Awardees Lauren Ferrante and Kathryn Callahan in this Pilot Awardee Spotlight! Learn more about their Inter-NIA Center pilot project here: bit.ly/4izqwNF #Frailty #AgingResearch

Honored to be recognized as one of 25 Best Leaders by @usnews.com including 5 in the Health category. I look forward to meeting some extraordinary colleagues at an upcoming event in Wash DC www.usnews.com/news/leaders...

The Trump admin has been targeting whistleblowers, from the #FEMA36 to the countless other patriotic public servants and scientists across NIH, CDC, NASA, and more who spoke out about the danger posed by the chaos in our federal agencies. This is an concerted, autocratic effort to silence dissent.

New research from Dixit lab @yalemed.bsky.social showing nerve-associated macrophages (NAMs) decline in aging which impairs the breakdown of fat and increases inflammaging. Dixit addresses the biology of aging and intercommunication between nerves and macrophages. www.nature.com/articles/s43...

Taliban Bans Books by Women in Afghanistan’s Universities www.nytimes.com/2025/09/19/w...

Congratulations to our outstanding @yalemed.bsky.social colleague @virusesimmunity.bsky.social

Count on #macrophages to promote health! Congratulations to my @yalemed.bsky.social colleagues for this very novel paper.

mRNA technologies: Unlimited potential to improve human health. I spoke with the fantastic Erin Shumaker at POLITICO to discuss this topic and its applications to cancer, autoimmunity and beyond. @erinlschumaker.bsky.social @politico.com @cornertx #mRNA #Cancer politi.co/3VjfRvu

#Resource Proteomic characterization of varicella-zoster virus–host protein interactions and infection-induced changes in a neuronal cell line identifies potential targets for drug discovery and molecular insights into severe disease. #MicroSky www.nature.com/articles/s41...

Come get your curated #immune #assays from 1,000s of human subjects at our website immunespace.org 🧪 #immunology #IDSky #ImmuneSky immunespace.org/query/filters giphy.com/gifs/Giflyti...

On Aug. 1, ASM & partner societies filed an expanded amicus brief with SCOTUS to defend scientific integrity & protect early-career researchers. The brief highlights the harm caused by NIH grant terminations, including canceling the MOSAIC program. asm.org/press-releas...

The NIH budget will INCREASE by $400 million — not slashed by 40%, as Trump proposed — according to a proposal by Senate appropriators, says Sen Murray. "Some have asked if there will even be an NIH by [2029]. The commmittee's resounding message is yes—Congress has your back", she says.

More insights from #IMPACC studies, including polymorphism that might protect in #covid19 in online publication. Authors include: @skleinstein.bsky.social @bjoernpeters.bsky.social @sesmalab.bsky.social @vivianasimonlab.bsky.social @joanndarce.bsky.social ++ others insight.jci.org/articles/vie...

Our collaborators identify chief predictor of #covid19 severity + death. Many authors include members of #IMPACC network: @rrmsky.bsky.social @bjoernpeters.bsky.social @skleinstein.bsky.social @sesmalab.bsky.social @joanndarce.bsky.social @droferlevy.bsky.social www.frontiersin.org/journals/med...

Welp. www.wsj.com/health/healt...

Three members of the NIH council of councils publish a letter to the editor, coming out against proposed budget cuts and recent grant terminations “The NIH is not just a national treasure — it is a global beacon of biomedical excellence. … We must not weaken it.” www.nature.com/articles/d41...

Really cool stuff! @dremilygoldberg.bsky.social @astratman.bsky.social @bbparis1984.bsky.social @balynzaro.bsky.social

Excited to be involved with this work driven by @dremilygoldberg.bsky.social and her team! Read the preprint now! "Neutrophil TLR2 signaling promotes lipid accumulation and vascular plaque growth"

NEW: In an unprecedented move, the NIH will soon disinvite dozens of scientists about to take positions on advisory councils that make final decisions on grant funding. NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.

Excited to see this new review piece that we wrote together with Jennifer Garrison and Alison Kochersberger on the modern tools and approaches to study #ovarian #aging out this week at @genesdev.bsky.social! genesdev.cshlp.org/content/earl... #GeroSky #WomensHealth 🧪🧬 A 🧵1/3

Our collaborator Purvesh Katri, and others, discover a #signature of #immune health. med.stanford.edu/news/all-new... @stanfordimmunology.bsky.social

Well annotated, curated, multiparameter FREE #immunology data, folks!

New Science story about the beginnings of grant reinstatement. www.science.org/content/arti...

Wow, when lower IFN in aging is a good thing! Congratulations Chaz L and team. #ImmuneProfiling #Aging Epigenetic attenuation of interferon signaling is associated with aging-related improvements in systemic lupus erythematosus | Science Translational Medicine www.science.org/doi/10.1126/...

“In a study that enrolled 5000 healthy adults before the flu season started and followed them until after it ended, the highest dose of the drug provided 76.1% protection from disease, compared with a placebo shot, its developer, Cidara Therapeutics, reported in a press release& on an investor call”

News: The American Academy of Pediatrics says it will no longer take part in the process of ACIP meetings. “We won’t lend our name or our expertise to a system that is being politicized at the expense of children’s health,” the group's president says. www.statnews.com/2025/06/25/c...

“Cassidy’s comments — including that the panel’s upcoming meeting be canceled until it is “fully staffed with more robust and balanced representation” — represent the harshest condemnation of Kennedy’s actions by the senator, who ultimately cast the key vote that secured Kennedy’s confirmation.”

Wow, this was an incredibly powerful statement put out by the now fired CDC ACIP members, published yesterday in JAMA. Snippets posted below: jamanetwork.com/journals/jam...

The firings break a key promise to Sen. Bill Cassidy that RFK Jr. would not alter the panel in any way. "Now the fear is that the ACIP will be filled up with people who know nothing about vaccines except suspicion," Cassidy wrote on X.

Real vaccine science, check it out

A colleague, a friend and a brilliant scientist. The US lost a trusted vaccine expert to an anti-science purge at #ACIP Americans should be outraged.

Breaking news: Staff at the National Institutes of Health have issued a declaration calling on their director to depoliticize the agency and reverse spending cuts.

@standupforscience.bsky.social supported more than 300 staff at NIH to release a statement urging Director Jayanta Bhattacharya to reject policies that undermine the NIH mission. AAI members can sign an open letter, publicly or anonymously, supporting this statement: ow.ly/Ckwe50W6u6g%...

In an extraordinary public rebuke, career NIH employees wrote to Trump health officials that they feel “compelled to speak up when our leadership prioritizes political momentum over human safety and faithful stewardship of public resources.” kffhealthnews.org/news/article...