“The prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.”

Very well done story on 60 Minutes about the harms of grant terminations and freezes at Harvard with Joan Brugge, Don Engbar, David Liu, and a very compelling young cancer patient, now cured with Liu's technology. Transcript and video here www.cbsnews.com/news/researc...

Genetically incorporating environment-sensitive noncanonical amino acids containing rotor-based fluorophores to target proteins enables real-time visualization of microenvironment changes in protein substructures www.nature.com/articles/s41...

Jennifer Nemhauser’s and my tribute to our amazing friend and mentor, the extraordinary Joanne Chory. Read about our personal and professional reminiscences. Thanks to all who provided background for this. www.pnas.org/doi/10.1073/...

Here’s some of what scientists told us: "The past five months are by far the worst I've experienced in my science career (from grad student to professor) over the last 30-plus years because we no longer know if there will be support for the work that we do, because science and research has…” +

Unique biological, exposomal, economic and sociocultural factors shape resilience and brain health across the globe. A Review in Nature Medicine discusses underlying mechanisms of resilience. go.nature.com/4l76HNh #medsky 🧪

Joanne Chory (1955–2024): Plant geneticist extraordinaire | PNAS www.pnas.org/doi/10.1073/...

Outrageous. The White House is sidestepping Congress and halting up to $15 billion in NIH research funding, which would have gone to study diabetes, cancer & more. The order was issued through a four-sentence email sent to NIH directors from Office of Management & Budget Director Russell Vought.

. #Botany2025 My institution (JIC in Norwich, UK) is hiring for a tenure-track Group Leader in Discovery Plant Sciences - see more here: www.jic.ac.uk/vacancies/gr... Let me know if you have questions!

Decreased funding, reduced opportunities and growing uncertainty has made life tough for international postdocs living in the US go.nature.com/4mg4ct9

Happy birthday Rosalind Franklin (1920 –1958), #chemist & x-ray crystallographer whose x-ray diffraction images were instrumental to discovering double-helix structure of DNA, made important contributions to carbon & virus research, was 1 of the great scientists of the 20th century.⁠ 🧪🐡👩🏼‍🔬 #histsci 🧵

Tenure-track faculty search of the UCSF Biochemistry & Biophysics Department is open for applications! We are looking for creative, innovative scientists asking fundamental questions in any area of biology. Join our vibrant, collaborative, and supportive community! aprecruit.ucsf.edu/JPF05702

"NIH has ..implemented a new policy requiring that at least one-half of the remaining funds for competing research project grants (RPGs) in FY 2025 be used to upfront fund RPG competing awards. Upfront funding provides the funding for all years of the approved project period .. from one fiscal year"

Hundreds of employees at the EPA released a “Declaration of Dissent” today, accusing EPA officials of politicizing the agency and undermining its core mission to “protect human health and the environment.” scim.ag/4lB937S

Where has industry been the past several months? Better late than never I suppose…..

The Trump administration has canceled billions in research grants to Harvard, imperiling critical scientific work. This has prompted the university to seek new funding models and raises questions about the future of US science funding. #AcademicSky 🧪

A federal judge on Monday declared the Trump administration’s move to cut hundreds of grants issued by the National Institutes of Health illegal, accusing the government of discrimination against minorities and L.G.B.T.Q. individuals. nyti.ms/4jSIjOG

If you’ve ever travelled across multiple time zones, you may already know a bit about #jetlag. What symptoms do you experience? Check out our full factsheet on Jetlag here: www.bioclocks.uk/factsheets #chronobiology #scicomm 🧪

Plant biologist Joanne Chory spent her career trying to grow plants that could sequester CO2 in their roots. Her wild ideas took hold. Learn about her outstanding career and legacy in Ep. 4 of “The Leap" with @hypothesisfund.bsky.social‬. 🔊 Listen here: buff.ly/yLqDcDL

🧠📉 The 'pivot penalty' in science A new study in @nature.com finds scientists get cited less after switching research fields – the bigger the shift, the steeper the drop. 🔗 doi.org/10.1038/d415... #SciComm #AcademicSky 🧪

There are 2 previous historical cases of countries destroying their science and universities, crippling them for decades: Lysenkoism in the USSR and Nazi Germany. The Trump administration will be the 3rd. It's not just budgets but research, institutions, expertise, and training the next generation.

Furiously logging all the new budget news, laughing grimly that it landed *just after* we hit publish. Of course it did. Grateful that the entire point of @unbreaking.org is to give us a durable platform where we can keep integrating new developments. We'll digest, contextualize & update next week.

Super happy to share our latest in @natcancer.nature.com co-led by @pannunziolab.bsky.social! We review the complex role of the circadian clock in genome integrity, DNA repair, immunity, metabolism, and cancer with a specific focus on early-onset cancer. Check it out! www.nature.com/articles/s43...

Why are animal models useful for CNS drug discovery? zendudest.substack.com/p/why-animal...

Dr. Katalin Karikó spent decades experimenting with mRNA. She was scoffed at, demoted, and eventually forced to retire. Then, she won a Nobel Prize. Her story is the first in our 10-episode series, “The Leap,” produced with the Hypothesis Fund.

A new ultrasound-guided #3Dprinting technique could make it possible to fabricate medical implants in vivo and deliver tailored therapies to tissues deep inside the body—all without invasive surgery, researchers report in Science. scim.ag/4dlUh1Y

Using computer modeling, scientists at Scripps Research show how bNAbs recognize HIV by interacting with MPER—a membrane-proximal, hard-to-access region—and surrounding lipids, structures long thought too risky to target, in work published in @elife.bsky.social.

Against measles, do 3 drugs or vitamins that RFK Jr. just said are "good" & "effective" remedies work? Nope, and I explain why in this Scientific American story. Meanwhile the measles outbreak keeps growing. www.scientificamerican.com/article/do-a... 🧪 🩺

Innovation in action🔬 🧬 A team of researchers from the Keck School of Medicine has developed an advanced tool for analyzing chimeric antigen receptor (CAR) T cells, paving the way for more precise, effective cancer therapies. #Science #CancerResearch #MedSky keck.usc.edu/news/usc-tea...

Glad to share our latest paper on optical biosensors for diagnosing neurodegenerative diseases: www.nature.com/articles/s44... @natureportfolio.nature.com @uazbio5.bsky.social

A Review in Nature Reviews Drug Discovery discusses the implementation of biomarkers in clinical trials across various neurodegenerative disorders, focusing on the context of use, to help expedite and de-risk drug development. go.nature.com/44Fxpb5 🧪

Come inside and explore the new Dr. Allen and Charlotte Ginsburg Human-Centered Computational Hall @sac.usc.edu @csatusc.bsky.social click the link to watch the full version: youtu.be/vqR2jYTvXTw

Reducing high blood pressure substantially lowers the risk of dementia and cognitive impairment without dementia, according to the results of a clinical trial published in Nature Medicine. go.nature.com/44z6kGy #medsky 🧪

"Along with 50 scientists from the SPHERA Consortium, which comprises leading research institutions across the European Union, we have drafted a declaration on the defence of science" https://go.nature.com/3Exty5y

My article with @agarfinkel.bsky.social titled "𝗔𝗿𝗲 𝗽𝗵𝘆𝘀𝗶𝗼𝗹𝗼𝗴𝗶𝗰𝗮𝗹 𝗼𝘀𝗰𝗶𝗹𝗹𝗮𝘁𝗶𝗼𝗻𝘀 𝙥𝙝𝙮𝙨𝙞𝙤𝙡𝙤𝙜𝙞𝙘𝙖𝙡?" has ranked as a Top Viewed Article by Wiley. Check it out if you haven't done so: onlinelibrary.wiley.com/doi/full/10.... #TopViewedArticle

I have a PhD project funded by the John Innes Foundation, "Uncovering Genetic Drivers of Gene Expression in Elite Wheat Varieties", from the 1st of October 2025. #wheat #bioinformatics Apply now www.earlham.ac.uk/studentship/...

I'm turning final corner on book in works for 4 years about scientific efforts to prevent future pandemics. Knopf plans to publish in October and now has teaser up. Deeply grateful to @sloanfoundation.bsky.social and many others for the support! www.penguinrandomhouse.com/books/690752...

Threats to US biomedical research grants at the NIH are coming thick and fast — and so are the lawsuits. Here, Nature unpacks the legal claims. https://go.nature.com/4idgY9d

Vaccines have granted families in wealthy countries the luxury of forgetting what measles, polio, rubella, and other preventable diseases are like. We're looking at how many millions of lives vaccines have saved. Read the full story: https://go.nature.com/4jqOqKn

Great article by @nobelprize.bsky.social laureate @ardemp.bskyverified.social outlining the health, economic and national security benefits of US biomedical research, and the devastation of government efforts to destroy our leading edge. www.cnn.com/2025/04/09/h...

Studies of researchers globally suggest there is a mental-health crisis in academia https://go.nature.com/3RNAbmZ

'Bluesky has overtaken its flailing rival X in hosting posts related to new academic research, indicating the platform is fast becoming the go-to place for scholars to share their work.'

Public-health specialists worry that misinformation and funding cuts could affect vaccination rates. To illustrate the impact of vaccines, Nature examines the millions of lives that they have saved through these five charts. #medsky 🧪

Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.” A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world. www.cnn.com/2025/04/09/h...

We were just notified that our contract to UCSD and Scripps Research to support wastewater surveillance in San Diego (searchcovid.info) was terminated immediately for the same reasons 👇. That means no more genomic wastewater surveillance, and our proposed extensions to measles, Hep A, others, gone.

Texas measles outbreak update today, up 14% since Tuesday (actual cases likely 4-5X reported) And further spreading in New Mexico and multiple other states throughout the US.

Another $2.6 billion in cuts to NIH are coming by next Tuesday www.statnews.com/2025/04/03/n... The shredded image fits

Huge congratulations to @thechunglab.bsky.social - who has just been elected a 2025 @aimbe-official.bsky.social Fellow. viterbischool.usc.edu/news/2025/03...

Only 9% of >105,000 people with 30-years of follow-up reached age 70 without chronic diseases. Our diet and healthy aging, a review of the new report @naturemedicine.bsky.social this week, and placing it in context erictopol.substack.com/p/our-diet-a...