Excited to share work published in @cp-cancercell.bsky.social by @yijuan.bsky.social showing that macropinocytosis inhibition drives myCAF-to-iCAF conversion, enhancing therapeutic responses in pancreatic cancer. Thank you to our collaborators that contributed! www.sciencedirect.com/science/arti...

"Nature has learnt that … some staff members are screening candidates’ social-media presences to check whether they have expressed negative views about the Trump administration or been involved in diversity, equity and inclusion (DEI) efforts … at their institutions." www.nature.com/articles/d41...

Science story about termination of terminations... www.science.org/content/arti...

A number of firsts this year including my first time participating in commencement @ucirvine.bsky.social and hooding my first 2 graduate students that have earned their PhDs!! Congratulations Valeria and Melissa! You are both amazing and this is only the beginning! 💪🧬🧪🦸‍♀️🦸‍♀️

The findings at the recent trial and today's Columbia chaos is pushing me to the edge. I just sent the following email...

Here is a link you can blast out to all of your networks to ask them to consider signing on in support of our NIH heroes. actionnetwork.org/forms/add-na... We are at 5000 folks who have signed on. But we can do better Only for people who have ever been sick or knows someone who has been.

Looking forward to sharing our recent work at #SLEEP2025! Circadian Medicine session starting in about an hour and I’ll be discussing approaches to timing cancer immunotherapy. See you there!

race does not equal genes www.statnews.com/2025/06/05/n...

Thanks to @npr.org and the Shortwave podcast for covering circadian research! It was very cool to be on the podcast and on All Things Considered. And Kudos to Chris Hall for the exciting work. www.npr.org/2025/05/29/n... www.npr.org/2025/05/30/1...

Check out our latest story @natcancer.nature.com co-led with @masrilab.bsky.social that reviews how the circadian clock intersects several aspects of cancer biology. Excited to be part of this collaborative team effort to understand impacts on DNA repair, early onset cancer, and cancer treatment 💪🧬🕔

Super happy to share our latest in @natcancer.nature.com co-led by @pannunziolab.bsky.social! We review the complex role of the circadian clock in genome integrity, DNA repair, immunity, metabolism, and cancer with a specific focus on early-onset cancer. Check it out! www.nature.com/articles/s43...

Celebrating UCI school of medicine graduate students 🧪🧠 . You are the future of #science @ucirvine.bsky.social @cnlm.bsky.social @neurohoke.bsky.social

I just emailed my state representatives to support Newsom's new budget for UC. If you agree that this economic and social engine for California needs robust state support, please join me. universityofcalifornia.quorum.us/campaign/sta...

We had previously shown that TBX3 and #WNT cooperate in limb #DevBio We now have a shocking finding, just published in @pnas.org TBX3 physically engages with β-catenin to drive metastasis genes in #ColorectalCancer (CRC) www.pnas.org/doi/epub/10....

Fresh out of press: our new chapter on the TBX3/WNT liaison, and how it drives metastasis-related genes expression in colorectal cancer, out on @pnas.org Enjoy the “bluetorial” by @claudiocantu81.bsky.social below! 👇🏼 #WNT #CRC @liu.se www.pnas.org/doi/10.1073/...

New preprint! 🧓⚡️ Aging drives immune exclusion & metastasis in PDAC by rewiring the tumor stroma. Young CAFs ♻️ rejuvenate the aged microenvironment & restore immune infiltration. Read: www.biorxiv.org/content/10.1... #PDAC #Aging #TumorMicroenvironment #Preprint

Just watched this episode. John Oliver did an outstanding job breaking everything down, even what indirects costs are! It’s our job to get all this information out, especially to inform the general public. This needs to stop. Now.

Sunday TV viewing...More to come later Lead story about NIH... www.paramountpressexpress.com/cbs-news-and...

President Donald Trump’s administration appears to be killing much, if not all, of a historic initiative that was the first, and is still the largest, National Institutes of Health effort centered on the health needs of women. scim.ag/4jLeLTJ

This breaks my heart in ways I can’t quite describe.

New STAT story about the possible new NIH grants terms and conditions www.statnews.com/2025/04/21/t...

www.ucdavis.edu/research/lab... @ucdavis.bsky.social @ucdavishealth.bsky.social @ucdavisplants.bsky.social @ucdaviscns.bsky.social @ucdavispsych.bsky.social

STAT story about freezing all payments to Columbia, Harvard, Brown, Northwestern, Cornell, and Cornell-Weill Medicine. www.statnews.com/2025/04/18/n...

A presidential effort to revoke Harvard University's tax-exempt status could run up against a number of challenges, including violating federal law.

The cast and crew of Pannunzio Lab season 6! Despite everything going on we continue to grow and be productive. Their excitement about science is contagious. These are the people that keep me coming in every day 💪🫀🧬

My story about @kevinh-phd.bsky.social, nutrition and metabolism scientist at N.I.H., who felt compelled to take early retirement after experiencing censorship of his work under the new administration. www.nytimes.com/2025/04/16/w...

Today, we report that APOBEC3B targets unprotected single-stranded DNA at replication forks upon ATR inhibition, triggering a reaction cascade involving UNG2 and APE1 that leads to fork collapse and hyperactivation of PARP1, causing replication catastrophe. www.science.org/doi/10.1126/...

"After nearly five hours, he and his wife were released. They are now pursuing legal action. "It's not about the immigrants," his sister, told NBC10 Boston. "It's coming to us Americans, and it's going to go after all of us." www.nbcboston.com/news/politic...

If a student you know received an honorable mention for the NSF GRFP, encourage them to contact their Congressional representatives! 🧪

@ucdavis.bsky.social senior admin, I sincerely hope y’all a robust response to this planned.

They are now estimating 2.3 million across the country. Keep it going folks. #handsoff #50501protests

I'm no good with patterns. Can someone help me out here?

Temporary restraining order issued last night for the public health-related lawsuit against HHS on Tuesday) www.nytimes.com/2025/04/03/u...

Finally got the notice. Very sad day for the MOSAIC program that supported some of the most amazing scientists I know, as well as some of the awesome people on my lab.

After getting some rest, I am in awe of everyone who continues to lift their voice and speak out. This is a moment for our country, and we must make a choice about the America we want to be.

Please vote and support our work @ucirvine.bsky.social!! @statnews.com

Please vote!! Please help us send @ucirvine.bsky.social to the finals of #STATMadness @statnews.com

Please vote!! Please help us send @ucirvine.bsky.social to the finals of #STATMadness @statnews.com

We need your support! @ucirvine.bsky.social has made it to the semifinals in #STATMadness @statnews.com. We need your support to send us to the finals!!! Let’s goooooo!!!! www.statnews.com/feature/stat...

A teeny bit of information officially from NIH... nexus.od.nih.gov/all/2025/03/...

Please vote and send us to the next round!!! @ucirvine.bsky.social

ATTENTION If anyone has any experience with appealing terminated grants (either the process or successful strategies 😀), please DM me. THANK YOU!

A sad day for Columbia and for our democracy. "Additionally the school believed there was considerable overlap between needed campus changes and Trump’s demands" has got to be one of the most depressing sentences ever written. www.wsj.com/us-news/educ...

Yay: Most postponed study sections have been rescheduled at this point. Yikes: To do this, CSR has scheduled *289* study sections from 03/24-05/16/2025. For comparison, there were only 96 study sections from 3/24-5/17/2024. And NIH still plans to RIF more staff. docs.google.com/spreadsheets...

“Unless you're a tech billionaire, this is going to lead to a worse future for you and the people you care about. Expect AI to be unfair, discriminatory, unsafe, and deployed irresponsibly,” And the major AI companies in the U.S. are complying. We’re compiling lists. www.wired.com/story/ai-saf...

Looking forward to this!

Updated the NIH CSR study section tracking sheet to include meetings originally scheduled for 03/17-03/21. There are now over *two hundred* study sections that didn't meet as scheduled. Likely an undercount due to things I couldn't scrape orig date was removed. docs.google.com/spreadsheets...

Calling on all Blueskies to help @masrilab.bsky.social by voting in the STAT Madness competition; a friendly competition for bragging rights. They've made it to round 2 and you can help them go all the way! Set up a free account and vote up to 5x per round! Go UCI! www.statnews.com/feature/stat...

In 2024 NIH grant awards supported 407,782 jobs and $94.58 billion in new economic activity nationwide, the largest figure in the history of the report. www.forbes.com/sites/michae...