UC Davis Center for Neuroscience (@ucdaviscns.bsky.social)

How are memories transformed and moved over time between brain regions? Read paper in @pnas.org by Brandon J. Bhasin, Dr. Jennifer L. Raymond & Dr. Mark S. Goldman. Stanford Wu Tsai Neuroscience Institute @stanford.edu & UC Davis Center for Neuroscience collaboration.: link.growkudos.com/1ozs0mh0av4

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How memories are transferred between brain regions during consolidation How are memories transformed and moved over time between brain regions? We propose a simple organizing principle for how long-term memories are moved from an initial to a final site of storage, a process known as "memory consolidation." We show that successful transfer occurs when the late site of memory storage is endowed with synaptic plasticity rules that stably accumulate changes in activity occurring at the early site of memory storage. We instantiate this principle in a simple computational model that is representative of brain circuits underlying a variety of behaviors. The model suggests how a neural circuit can store new memories while preserving core features of older ones and proposes functional roles for core elements of the cerebellar circuit. https://link.growkudos.com/1ozs0mh0av4