The love of my life turned 21 today! The joy this little monkey has brought us is indescribable!! So proud of her 💕

Gutted by the news here and in Australia.

There are a lot of ways to be 💩in this world; the work of clinician-scientists is one of the best ways to still get to act with honor (This one goes out to those of you working this Friday night in house. Thanks for keeping our patients safe)

Whipped up a Sri Lankan feast for friends and colleagues in town for ASCB! So fun :)

Our family tradition is for my hubby to lift up our girl to place the star on the Xmas tree. It’s getting harder, but funnier!!

Thankful for so much.

The November 2025 edition of the Ludwig Link is here, and it's our largest ever! Catch up on the latest from Ludwig researchers, including awards, a new appointment & engaging conversations with three early-career scientists. Check it out online here bit.ly/3XfYVqV or download the PDF bit.ly/4poMsgA

Epstein survivors just dropped a powerful message for Congress, and it hits like a warning: no more waiting, the truth is coming, ready or not. Watch till the end @housedemocrats.bsky.social @houserepublicans.bsky.social

@michaelhoffman.bsky.social Small world!!

The strides my GI colleagues at Johns Hopkins Kimmel Cancer Center are making in the fight against pancreatic cancer are amazing!

This!!!

I have no words.

www.nature.com/articles/s41... Lymph node environment drives FSP1 targetability in metastasizing melanoma

Races in this election cycle were called mostly in under an hour representing a resounding mandate and indication that indeed what we all want is the best for everyone- for the people, by the people. Hope.

I do biomedical research to help people. When people come in this space making things up, it makes it harder for people not in the field to trust the extensive studies that we do and distinguish fact from fiction. Baseless claims reduce future cures. Willful ignorance drives us backwards.

Lol sob

As Vought tweets out 'The RIFs have begun', it will be crucial to speak up in support of the mission-driven folks all across this country who are being targeted precisely because they dedicated their professional careers to serving the public. apnews.com/article/gove...

'When authoritarians seize power, it is crucial to recognize courageous defenders of freedom who rise and resist,' the Norwegian Nobel Committee said as it announced Maria Corina Machado as the winner of the 2025 Nobel Peace Prize

Democracy won today. A huge congratulations to Maria Corina Machado!

I am so proud to say that our paper is now available at Aging Cell. There is a paucity of data as to how the menopause impacts your immune system, and the aim of this study was to investigate the impact of the menopause on monocyte phenotype and function. onlinelibrary.wiley.com/doi/10.1111/...

Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years? A 30-year long mystery unraveled @ScienceMagazine today! Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation www.science.org/doi/10.1126/...

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

“It actually doesn’t take much to be considered a difficult woman. That’s why there are so many of us.” ― Jane Goodall 💙 RIP to a real one. My childhood hero

Amazing talk by @peterhotezmdphd.bsky.social at Hopkins yesterday. What an amazing person!

Normalize just posting a recipe with no backstory at all.

Maybe it’s the stress of the times. Maybe it’s needing to control one small thing in my crazy life, when I see this house once every few weeks. But today my linen closet got the brunt of my angst 😂

These are the stars with which I grew up. It was one of the things I missed most, among the many I missed (!!) when I moved to America.

Danger, Will Robinson.

Check this out: This is what the human fallopian tube looks like as one travels through its different sections. We have developed a new 3D single-cell tissue mapping workflow to automatically/accurately detect ovarian cancer precancerous lesions (STICs). More here: www.biorxiv.org/content/10.1...

Review 🚨 Easwaran&Weeraratna outline how #ageing leads to epigenetic alterations in the #TME, enhancing clonal expansion of mutations and ultimately increasing cancer risk. 📖 👇

A huge shoutout to all the dedicated grants management specialists at the NIH who are working around the clock to push grants out before the Sep 30 deadline. And also to the POs responding to frantic emails. Not an easy job under the best of circumstances and right now it's the pits. Thank you!

I’m just going to say this lantern fly situation is untenable. First, one got into the revolving door with me. Then, one followed me into my uber. THIS CANNOT STAND.

Went for the over 50 trifecta yesterday- covid, flu and shingles vaccines. A little tired, sore arm but otherwise fine.

Lovely having @richardsever.bsky.social visit. Really brought home the value of preprints and has me scratching my head as to why I’ve not taken advantage of this?

Adorable chicken parm meatballs, grilled veggie salad, Caprese salad, and roasted hot honey carrots with pistachios and feta. Paired with balsamic chicken and rigatoni not shown.

"Go to an old cemetery. See all the baby graves from before the 1950s & 60s? After that, hardly any. That's when people started vaccinating their children. If you're unsure what to do to protect your kids, the answer is literally written in stone." — Michael Okuda How quick we forget.

Cocktail hour. My new fave thing to make is upside down flatbread, my old fave things are charcuterie boards and mango garlic shrimp!

OK, blue sky followers I need advice. I deactivated my Twitter account, but somehow the profile still stayed up. I no longer have access to it because it thinks I’ve deactivated it. Yesterday a bot took it over changed the username and is spamming all my former followers- what to do?

“Less encumbered by cynicism… students see the world with a moral clarity & urgency that institutions lack. That’s why we must listen to their voices,not silence them…The sign in my office window may be gone, but the choice to honor what it symbolized is still ours to make. Let’s do the right thing”

Yes, this... 👇

I never thought that so much progress and potential could be eradicated so quickly. How naive I was.

Imagine explaining to Bill Watterson while he was drawing this that "Calvinball" would one day appear in a United States Supreme Court dissent

Wow. This article is mind blowing.

In a normal funding environment, all of these applications would be awarded. This is what it looks like when outstanding science is left on the table. A tragic and painful failure of our national leadership.

People weren’t healthier “back in the day.” In 1960s, life expectancy was in the 60s vs. 79 today. Testicular cancer? 95% fatal. Today? 95% survivable. Same with MANY cancers. Infections. Vaccine-preventable illness. We live longer & healthier lives today bc of science. youtu.be/rDx7LrBiMH0?...

Had to post this pre-hurricane #Bluesky

👇🏻

Excellent to see this commitment to include older adults in research. Cries of ‘wokery’ will be fewer & quieter for the protected characteristic of age, yet the principles of equity and inclusion are the same as with sex, gender, ethnicity & pregnancy status. All matter www.ukri.org/news/committ...