Yijuan Zhang
@yijuan.bsky.social
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Cancer Biologist;Cancer Metabolism; Cancer Immunotherapy;Tumor Microenvironment
reposted by
Yijuan Zhang
Cosimo Commisso
5 months ago
Excited to share work published in
@cp-cancercell.bsky.social
by
@yijuan.bsky.social
showing that macropinocytosis inhibition drives myCAF-to-iCAF conversion, enhancing therapeutic responses in pancreatic cancer. Thank you to our collaborators that contributed!
www.sciencedirect.com/science/arti...
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Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) tumors are glutamine deficient, and both tumor cells and cancer-associated fibroblasts (CAFs) rely on this ami…
https://www.sciencedirect.com/science/article/pii/S1535610825002715
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