1/10 🧵NEW PREPRINT: How does jaundice protect against malaria? We show it's ALL about biliverdin reductase (BVRA) catalytic activity and found the bilirubin threshold needed for protection. www.biorxiv.org/content/10.6...

@EMBO Practical Course Pipetting scRNA-seq data into computational cells 18 – 23 May 2026 | Oeiras/Lisbon, Portugal @gimmfoundation.bsky.social Registration open!

Homeostatic control of energy metabolism by monocyte-derived macrophages @elmiguelche.bsky.social and colleagues show that macrophages sense dysregulated iron metabolism in parenchymal cells and respond by sustaining mitochondrial function in affected cells www.embopress.org/doi/full/10....

🧵 Thrilled to share our new work in @embojournal! Over a century after Metchnikoff recognized macrophages as central to organismal homeostasis, we reveal how they act as metabolic guardians through an unexpected mechanism. www.embopress.org/doi/full/10.... (1/9)

of the influenza vaccine is low (against infection). What is forgotten is the protection from non-communicable diseases. What if you could reduce your risk to heart disease by 40%? What is you could reduce you risk to dementia by at least 10%? That is what vaccines do! 3/10

Food for thought from: ‪@lferreiramoita.bsky.social‬ in JCI - Biological and clinical implications of a model of surveillance immunity www.jci.org/articles/vie...

At Folha de São Paulo: folha.com/38iy72bz @gimmfoundation.bsky.social

Beautiful new work from Maz Divangahi lab about the enhanced anti-tumoral activity of β-glucan + BCG trained neutrophils leading to tumor eradication. #freshoffthepress @cp-immunity.bsky.social

A recent study based on observations in humans and experiments in mice proposes that induction of bilirubin production in response to Plasmodium spp. infection is an evolutionary conserved mechanism against malaria. 🧪 www.science.org/doi/10.1126/...

Rewring lipid metabolism to sustain thermoregulation during sepsis. Don’t let it get cold! A very interesting piece from Miguel Soares lab @elmiguelche.bsky.social @gimmfoundation.bsky.social

The future of heart health: AI, immunity, and personalized prevention | Science | AAAS www.science.org/content/webi...

Call for our new PhD program is open. Come join one of our labs at Gulbenkian Institute for Molecular Medicine - Lisbon-Oeiras, Portugal. Help us spread the word

A bioenergetic basis for multiorgan dysfunction in sepsis https://www.biorxiv.org/content/10.1101/2025.06.12.659280v1

Check out the paper from our latest collaboration with Miguel Soares's lab: 🦠A metabolite-based resistance mechanism against malaria Now out in Science: www.science.org/doi/10.1126/... @gimmfoundation.bsky.social @turkubioscience.bsky.social @inflames-flagship.bsky.social @utu.fi

Rethinking jaundice | Science @gimmfoundation.bsky.social

A metabolite-based resistance mechanism against malaria | Science www.science.org/doi/10.1126/... @gimmfoundation.bsky.social

There is a price tag for everything….. www.sciencedirect.com/science/arti... Evolutionary medicine in action: Sickle hemoglobin fuels tumor progression - ScienceDirect

Latest from the Nature Podcast 🔊 Male mice can grow female organs — if their mothers lack iron https://go.nature.com/3SY8I2V

🚨Great new MSc and PhD positions available @gimmfoundation! Check out the links or use the QR code. MSc: www.medicina.ulisboa... PhD: gimm.pt/course/phd-p...

Curious about aging & longevity research? Join us at GIMM Fest (Lisbon, Portugal) Discover groundbreaking insights & engage with top researchers. It's a celebration of curiosity & a catalyst for change. 🗓️ Sept 4-5: Scientific Sessions + Sept 6: Public Event 👉 gimm.pt/gimm-festival/

@cleeterichter.bsky.social & Kelsey Voss discuss a study from @elmiguelche.bsky.social that highlights a role for monocyte-derived macrophages in iron homeostasis and its control of systemic energy metabolism

Red blood cells undergo lytic programmed cell death involving NLRP3: Cell www.cell.com/cell/fulltex...

Is it still not clear? Abusing the state to force your ideology on others. Fascism, Fascism, Fascism. There is no other term for this. Jay Bhattacharya? 🤡🤡🤡 a useful idiot.

Important definitions and concepts to understand that what is happening in many countries is not new.

"Fascism is rising again". It's been back for several years, out in the open. But these four words may need an explanation and a warning. 1/3

Today in #preprinthub2 Kelsey Voss + @cleeterichter.bsky.social will present a #preprint from @elmiguelche.bsky.social @gimmfoundation.bsky.social on how monocytes control organismal energy homeostasis 🕹️🧍‍♀️🌊 www.biorxiv.org/content/10.1...

The U.S. National Institutes of Health’s recent decision to impose a 15% cap on facilities and administrative cost reimbursements is misguided and damaging, argue the authors of a new #SciencePolicyForum. scim.ag/423AbVX

More good news: MEP Christian Ehler's ITRE report adopted by the European Parliament: strong support for an expanded and independent ERC. Happy with the proposal of €220 billion for the EU's next research framework programme! Thank you! Press briefing multimedia.europarl.europa.eu/en/webstream...

Kennedy Links Measles Outbreak to Poor Diet and Health, Citing Fringe Theories. Story by @teddyrosenbluth.bsky.social Gift link: nyti.ms/3FvFUej

If our "academic leaders" are wondering what a real leader looks like, look no further. Who will follow Dr. Varmus? www.nytimes.com/2025/02/14/o...

François Jacob, who fought and was wounded in North Africa, meets his former commander in chief, General DeGaulle. (From Jacob's memoir, La Statue Interieure).

Excited to share that I am stepping in as the new Editor-in-Chief of the European Journal of Immunology (@eurjimmunol.bsky.social)! I feel truly honored to take on this role, following the outstanding work of my predecessors, Chiara Romagnani and Jim Di Santo. onlinelibrary.wiley.com/doi/full/10....

Here's a first collection of great life science institutes worldwide you can follow to help you get back in the loop. 🌍🔬 Did we miss any? Let us know, and we'll add them! go.bsky.app/A5Jrf8N