Looking for a postdoc? The @sciolinolab.bsky.social at UConn is hiring! We investigate how neuromodulatory systems interact with central taste processing regions to regulate behavior using in vivo recordings, optogenetics & mouse behavior. Apply: jobs.hr.uconn.edu/en-us/job/49...

Our evil ORFeome paper is out! In collaboration with @alex-stark.bsky.social, we screened ~4,000 viral proteins and secreted effectors from bacteria and parasites, covering hundreds of diverse pathogens, for phenotypes in human cells.

🚀 Job opening 📣 We are recruiting an Assistant Engineer in Gene Therapy (Adénovirus team – Eric Kremer Lab) @cnrs.fr @umontpellier.bsky.social 🔗 emploi.cnrs.fr/Offres/CDD/U... #Hiring #CNRS #IGMM #GeneTherapy #Neuroscience #LifeSciences #ResearchJob

#Parcoursup n'est pas seulement fait pour écraser les lycéens par l'angoisse et le contrôle permanent. Il est fait pour creuser les inégalités et les naturaliser, faire accepter une place dans la société largement déterminée par le capital éducatif des parents. www.nouvelobs.com/opinions/202...

Free and open-source images, icons, and tools for creating scientific illustrations doi.org/10.59350/5zt... 🧪

What does your science look like? 👀 The Best Scientific Image Contest 2026 deadline has been extended to May 13 & now includes €4,500 in total prize money. 🙌 Share your images & let it travel beyond the lab. Submit 👉 awards.helmholtz-imaging.de/site/index.php Open to everyone at @helmholtz.de.

OneOrangeBrainCell

🧠 Our new paper in @NatureComms is out! We uncovered a disrupted temperature-sleep coupling in a Dravet syndrome mouse model — and show SCN1A restoration can help. Dedicated to the memory of Dr. Saja Fadila 🕊️ 👉 doi.org/10.1038/s41467-026-69957-1 #DravetSyndrome #Neuroscience

Hot off the press! I'm thrilled to share that our paper "Unravelling the Maturation Pathway of a Eukaryotic Virus through Cryo-EM" has been published! Link to the paper: www.pnas.org/doi/10.1073/... Nature is full of remarkable protein nanomachines, and now we can watch one more in action.

Excited to share our new paper: We uncover a locus coeruleus→amygdala circuit linking β-adrenergic signaling to transcription regulation in defined amygdala cells during memory reconsolidation—+ stress or elevated noradrenergic signaling at recall can strengthen memory. www.cell.com/neuron/abstr...

Steven Spielberg, Denis Villeneuve : I’m free…

My project Degenerative Architecture has been on display on the façade of the Montpellier School of Fine Arts since last week.

New Special Issue out in #AddictionNeuroscience edited by @talialerner.bsky.social on dopamine circuitry and heterogeneity in addiction with articles by @daylab.bsky.social, Tom Hnasko, @mtorregrossa1.bsky.social, and Awatramani Rajeshwar check it out! www.sciencedirect.com/special-issu...

Despite decades of intensive research, current approaches to treating #NeurodegenerativeDiseases only slow down the seemingly inevitable. Could recent data associating #vaccines with reduced risk of #dementia offer an unexpected beacon of hope?🧪 @sparrerlab.bsky.social

There's a special place in hell for people who benefit daily from state of the art medical treatment and then argue that the means to discover the next state of the art treatment should be eliminated.

Great to see this officially out: An mTurquoise2-Based Glucose Biosensor - works in yeast & mammalian cells and is compatible with FLIM: pubs.acs.org/doi/10.1021/...

Tom Morello live in Minneapolis

After turning off ChatGPT’s ‘data consent’ option, Marcel Bucher lost the work behind grant applications, teaching materials and publication drafts go.nature.com/4qLPpcb

#ResultatScientifique🔎| Des parasites du paludisme pris au piège : une approche innovante pour lutter contre la maladie 🦠 ✍️ Rachel Cerdan 🤝 @cnrsoccitanieest.bsky.social @inserm.fr @umontpellier.bsky.social 📕 buff.ly/YZ7m9qz

How does your favorite gene respond to stress? Check out our updated “Stressome-app”! In a new @natcomms.nature.com paper we vastly extend our interactive app with loads of bulk and single-cell transcriptomics after acute and chronic stress. www.nature.com/articles/s41... I'll walk you through👇

#ResultatScientifique🔎| Un circuit neuronal qui énergise le comportement 🧠 ✍️ Emmanuel Procyk et @crewilson.bsky.social 📕 @currentbiology.bsky.social | buff.ly/Dv4XBOt buff.ly/S7OfpX3

In a groundbreaking study, an international team led by ETH Zurich researchers has for the first time calculated how many glaciers worldwide are likely to remain until the end of the century and for how long. It looks bleak. ethz.ch/en/news-and-...

« 𝐒𝐡𝐨𝐮𝐥𝐝 𝐈 𝐬𝐭𝐚𝐲 𝐨𝐫 𝐬𝐡𝐨𝐮𝐥𝐝 𝐈 𝐠𝐨 » : 𝐜𝐨𝐦𝐦𝐞𝐧𝐭 𝐥𝐞 𝐜𝐞𝐫𝐯𝐞𝐚𝐮 𝐚𝐩𝐩𝐫𝐞𝐧𝐝 𝐞𝐧 𝐜𝐨𝐦𝐩𝐚𝐫𝐚𝐧𝐭 Des scientifiques de l'IGF montrent que des neurones du noyau paraventriculaire du thalamus permettent aux souris de comparer leurs expériences présentes et passées afin d’évaluer danger et sécurité relatifs. urlr.me/Zsg2x9

Need help 😬 : anyone knows a good system to stop protein expression in mammalian cells (except degradon, Tet on/off prom, crispr, smash or trip system) ?

🎉 Félicitations à l’équipe de Stephanie Trouche Institut de Génomique Fonctionnelle - IGF, avec le soutien de l’équipe d’Éric Kremer (IGMM) et la plateforme de vectorologie Biocampus, pour leur publication dans @currentbiology.bsky.social 🧠✨ www.insb.cnrs.fr/fr/cnrsinfo/...

Feeling festive? Why not deck the halls with @cvrinfo.bsky.social's papercraft #VirusSnowflakes and celebrate the science of viruses and the fight against viral diseases. Download for free: cvr-engagement.co.uk/virus-snowfl... #scicomm #sciart #decorations

FDA approves Itvisma, expanding access to gene therapy for spinal muscular atrophy. The one-time intrathecal treatment is approved for patients two years and older – the first gene replacement therapy available for this broader SMA population. Read more: https://bit.ly/3Kn9mpM

👏Pauline Duc et @florage.bsky.social pour leur contribution à cette avancée publiée dans Nature Neuroscience : un microARN musculaire pourrait protéger les neurones moteurs et ouvrir de nouvelles pistes thérapeutiques contre la SLA grâce au financement ARSLA! www.arsla.org/quand-le-mus...

🧬 AAV not expressing? 🔍 Weak fluorescence? Here’s your step-by-step guide to fixing the most common AAV pitfalls—from titer and serotype to detection and sample processing. www.ebraincase.com/support/lite... #AAV #AAVVector #ViralVectors #GeneDelivery #GeneExpression #NeuroscienceResearch

Methodology

My lab is recruiting a post-doc ! please share ! emploi.cnrs.fr/Offres/CDD/U...

I forgot the settings on the last #FullMoon post. Here's a slightly different version though. #MoonPhotography #MoonPhotos #MoonShots #Photography Camera settings: Canon T5i Sigma 150mm x 600mm Focal length: 600mm F-stop: f/10 Exposure time: 1/1600 ISO: 800

Really delighted to share our new article in Current Biology showing that the cingulate-to-dorsolateral prefrontal pathway is not involved in trial-to-trial short-term adaptation but rather in sustained motivational control. doi.org/10.1016/j.cu...

'In this manuscript, we show that tag fusions often change protein expression to a degree that is highly dependent on cell and tissue context. We characterise two underlying mechanisms, providing information that should help others to design more effective transgenic strategies'

🧠Maladie d'Alzheimer⚡ Rétablir les rythmes électriques du cerveau par thérapie génique. Projet mené au sein de l'équipe dirigée par Eric Kremer et soutenu par @frm-officiel.bsky.social

Lecornu Sébastien succède donc à Sébastien Lecornu. (censure)

Viral interferon antagonism shapes host tropism journals.plos.org/plospathogen...

Damn, we had a government... for 14 hours

Just a reminder if you're getting a manuscript together (like we are) to thank your core facilities!

Should you plant goldenrods? Yes! And be a hero to migrating monarchs. Here’s showy goldenrod putting on a show for monarch butterflies and other pollinators #nativeplants #nativepollinators #homegrownnationalpark #mentalhealth

Check out the plasmids from this study! 👉 www.addgene.org/browse/artic...

Really cool stuff! Engineered excitatory opsins responding to 15nW light

🚨 Big news for the #SCN2A community 🚨 Landmark UCSF study shows CRISPR activation can restore SCN2A function — even later in development. A real step forward, and real hope, for families living with SCN2A-related disorders. www.prnewswire.com/news-release...

🚨 New paper alert! 🚨(1/6) Excited to share our work, out now in Science Advances We show that a rapid norepinephrine surge along a brainstem pathway (LC→PRN) is a key driver of sound-evoked awakenings www.science.org/doi/10.1126/...

Excited / nervous to share the “magnum opus” of my postdoc in Andreas Wagner’s lab! "De-novo promoters emerge more readily from random DNA than from genomic DNA" This project is the accumulation of 4 years of work, and lays the foundation for my future group. In short, we… (1/4)

Honored to have been invited to contribute to this comprehensive review on neuropeptide signaling and its impacts on the locus coeruleus noradrenergic system 🔵🧠🧪. www.sciencedirect.com/science/arti...

Stills from ongoing video (made with generative codes and found footage)