AAVs are crucial vectors for delivering biosensors into neurons! Using AAV delivery, we perform two-color imaging of calcium and potassium transients in neurons. These AAVs are now available from @braincase.bsky.social www.ebraincase.com/news/new-pro...

🔥The world’s first red fluorescent potassium sensors — RGEPO1 & RGEPO2 — are here! Developed by Kiryl D. Piatkevich’s team at Westlake University, these sensors enable real-time in vivo imaging of potassium ions 🔗 www.ebraincase.com/news/new-pro... #Neuroscience #RGEPO #PotassiumImaging #NeuroTech

🧬 Precision Gene Delivery to Brain Blood Vessels 🧠 The Woo-ping Ge Lab developed rAAV-miniBEND, a targeted AAV system for efficient, cell-specific gene delivery to brain endothelial cells—advancing cerebrovascular disease modeling. 👉 www.nature.com/articles/s41... #GeneDelivery #AAV #Neuroscience

✨🧠Client Publication|CRH Neurons Protect Against Acute Lung Injury A study by Xiangya Second Hospital,published in Nature Communications,reveals that PVN CRH neurons protect against ALI via the sympathetic–neutrophil axis through β₂-AR/β-arrestin2–NF-κB signaling 🔗 www.ebraincase.com/support/cust...

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✨🧠Breakthrough! Chinese scientists published in Cell: Gene-edited stem cells rejuvenate aging monkeys. FOXO3-modified mesenchymal progenitor cells (SRCs) reduced aging biomarkers, improved brain and reproductive health, and showed anti-aging effects via exosomes. 🔗 www.ebraincase.com/support/lite...

✨🎉Excited to see our collaborator’s @piatkevich.bsky.social latest post! The products are now available via Brain Case Biotech, supporting global neuroscience and gene therapy research. 🧠🔗Contact us at [email protected] for details www.ebraincase.com/products-ser... #AAVs #FRCaMPi #PiatkevichLab

✨🎉Excited to see our [email protected] latest post! The products are now available via Brain Case Biotech, supporting global neuroscience and gene therapy research. 🧠🔗Contact us at [email protected] for details. www.ebraincase.com/products-ser... #AAVs #FRCaMPi #PiatkevichLab

🧠 Client Publication | Nature Communications Prof. Zhong Chen’s and Academician Qingming Luo’s teams built a 3D single-synapse input atlas of histaminergic neurons in mice, revealing distinct LS and PVT circuit roles in REM sleep. 🧪 Viral tools from Brain Case. 👉 www.ebraincase.com/support/cust...

🔬 The patch-clamp technique enables precise recording of ion channel and neuronal activity—key for studying excitability and synaptic transmission. Brain Case Biotech provides full patch-clamp recording & analysis for cells and brain tissue. 🔍 www.ebraincase.com/news/corpora... #PatchClamp #Neural

🚀Discover BrainCase’s latest neuroscience tools! From Ark313 CAR-T/TCR-T vectors to GRAB-LoX3-1.0, SomaFRCaMPi,mYongHong&rAAV-13—cutting-edge viral vectors and sensors for precise gene delivery & high-resolution imaging🧬 🔗 www.ebraincase.com/news/corpora... #Neuroscience #ViralVectors #GeneEditing

🧠 Client Publication | Neuron | University of North Carolina–Chapel Hill Team Reveals Distinct #Neural Circuits Driving Cognitive and Emotional Deficits in #Alzheimer’s Disease🧪 Read more: www.cell.com/neuron/abstr... 🧬Viral tools by Brain Case Biotech. www.ebraincase.com/support/cust...

✨New serotype Ark313 | A new AAV tool for T cell #GeneEditing 🧠 Cell study reveals AAV6 variant Ark313 enables efficient gene delivery in murine T cells—advancing T cell therapy research. Brain Case can provide the serotypes and related services. 🔗 www.ebraincase.com/news/new-pro... #AAV #Ark313

💖 World Mental Health Day 2025 ✨ Highly sensitive people process the world deeply; with empathy and support, their creativity shines. This Oct 10, let’s replace judgment with patience and value every mind. 🔗 www.ebraincase.com/support/lite... #WMHD2025 #SPS #MentalHealth #WorldMentalHealthDay

✨Client Publication🎉 Sun Yat-sen Univ. team reports that MSCs relieve pain by activating Npy2r lung–brain neurons via the vagus→NTS→vlPAG pathway, dependent on ATP signaling. Inhaling a P2rx2 agonist also eases chronic pain. 🔗 www.ebraincase.com/support/cust... #Npy2rNeurons #ATPsignaling #AAVvector

🎉 LIVE at CNS 2025 Xi’an! Visit Booth T9 to play our fun game, win exclusive Brain Case gifts 🐱✨, and grab the 2025 Neuroscience Frontier Handbook! 📅 Sept 25–28 | Xi’an International Convention & Exhibition Center www.ebraincase.com/news/corpora... #CNS2025 #CNSXiAn #Neuroscience #BrainScience

🔬Literature Review | 4 Photosensitive Receptor Tools Unveiled! 🧠✨ Discover how D1R, MOR, CB1R, and A2AR OptoXR enable precise, light-driven control of neural circuits and behavior, revealing powerful applications and key limitations. 👉 www.ebraincase.com/support/lite... #Optogenetics #Neuroscience

CNS 2025 is coming to Xi’an Sept 25–28! 3,500+ neuroscientists • 150+ symposia • 12 keynotes • 3 poster sessions. ✨ Brain Case Biotech brings frontier research tools & exclusive gifts. 📍 Visit Booth T9 for innovation & surprises! www.ebraincase.com/news/corpora... #CNS2025 #Neuroscience #BrainCase

🧠Research Services|Neural Circuit Tracing + Targeted Spatial Omics + Neuronal Classification Analysis (with Case)🧪 🔗 learn more about our services: www.ebraincase.com/news/corpora... #Neuroscience #BrainResearch #NeuralCircuits #Neurobiology #NeuroscienceResearch #BrainCaseBiotech

🧩 Together Against Alzheimer’s 🧠 World Alzheimer’s Day on Sept 21 reminds us to raise awareness, support research, and care for those affected. Early detection matters—let’s share knowledge and stand together for a future where memories last.💜 www.ebraincase.com/support/lite... #WorldAlzheimersDay

🎉 Customer Article Spotlight 🧠 Yi-Zheng Wang’s team (AMMS) reports in Cell Reports that VTA astrocytic Ca²⁺ signaling modulates GABA transmission, disinhibits DA neurons, and alleviates anxiety/depression-like behaviors. 🔗 Review: www.ebraincase.com/support/cust... #Neuroscience #Astrocytes #VTA

🔬 #PRV #NeuralCircuitTracing Service Empowering Peripheral–Central Research Brain Case is committed to providing customer-oriented solutions to support peripheral–central neural circuit research.We offer a comprehensive one-stop PRV neural circuit tracing service www.ebraincase.com/news/corpora...

🎗️World Suicide Prevention Day💙 Today, we stand together for understanding, prevention & hope. To anyone struggling: you are not alone. Please reach out for help, and remember—hope is always on the horizon 🌹🌹 www.ebraincase.com #WorldSuicidePreventionDay #HopeOnTheHorizon #MentalHealth

🚀🔬 New Insight into Cellular Autophagy! Discover how autophagy works, the role of LC3 markers, and how fluorescent viral tools help track autophagy pathways. 👉 Read more in our latest article: www.ebraincase.com/support/lite... #CellularAutophagy #LC3 #FluorescentTools #Neuroscience #Research

🎉🤩 Customer Article Sharing | Cell Research Fudan Univ. team reveals how NPTX1/2 downregulation destabilizes memory engram circuits, driving aging-related memory deficits.🧠 🧪 🔗 Review: www.ebraincase.com/support/cust... 🔗 Source: www.nature.com/articles/s41... #MemoryEngram #NeuroscienceResearch

Can light precisely control behavior? 🧠✨ With OptoXRs, researchers showed that activating specific intracellular pathways can drive reward-related actions in mice. 🔗 www.nature.com/articles/nat... 📍 www.ebraincase.com/support/lite... #OptoXRs #Optogenetics #Neurobiology

🎓 Back-to-School Promo | Sept 2025 🧬 AAV Vectors 20% OFF | 🧠 Neural Tracers 10% OFF | 🧪 Custom AAV Packaging — Up to 30% OFF | 🎁 Mystery Box $239（100 μL） | 🌈 Combo Pack $499（5✖️20μL）. 👉 Don’t miss it: www.ebraincase.com/news/corpora... #ViralVectors #Neuroscience #BackToSchool #BrainCaseBiotech

🧠✨ Miao Jing’s team at BIBR developed GRAB-LoX3-1.0, a fluorescent sensor enabling real-time, high-precision visualization of CXCL10 dynamics. This breakthrough reveals how chemokines encode immune signals in inflammation. 🔗 www.ebraincase.com/support/lite... #Neuroscience #Immunology #Research

🚀New in Cell: A toolkit of 1,000+enhancer AAV vectors and 17 transgenic mouse lines enables precise targeting of cortical cell types.Validated by single-cell sequencing and imaging, these tools advance brain research and disease studies. www.ebraincase.com/news/new-pro... #EnhancerAAV #Neuroscience

🧠🎉Client Article Sharing - Epigenetic reprogramming of HDAC2 in CA1 excitatory neurons determines Pb-induced non-spatial memory deficits. We are honored that the viral vectors used in this study were supplied by Brain Case Biotech🥰✨ www.ebraincase.com/support/cust... #Neuroscience #MemoryDeficits

🧠✨ Literature Insight | Using optogenetics, calcium imaging & retrograde viral tracing in human cortico-striatal assembloids, researchers revealed functional glutamatergic connectivity & disease-related activity changes in 22q13.3 models. 👉 www.ebraincase.com/support/lite... #NeuroscienceResearch

🧬 Power your research with Brain Case! Ready-to-use viral vectors for neuroscience & tumor immunology: RABV • PRV • HSV • VSV. Reliable tools. Broad applications. Faster discoveries. 👉Explore our full Product Library: www.ebraincase.com/virus-produc... #Neuroscience #NeuroResearch #ViralVectors

🧠🎉Client Article Sharing | Zixuan He & Xiaojuan Zhu’s Team at Northeast Normal University | A medial habenula neural circuit controlling anxiety-like behaviors in response to acute stress www.ebraincase.com/support/cust... #Neuroscience #NeuralCircuit #MHbNeurons #AcuteStress #AnxietyResearch #AAV

🎉✨Congratulations to Professor Xiaodong Liu and their team on publishing their groundbreaking work in Science Translational Medicine! We are honored that Brain Case Biotech’s viral tools supported this important study. 👉 www.ebraincase.com/support/cust... #Neuroscience #NeuralRepair #Optogenetics

🧠✨This study is the first to clearly demonstrate the presence of growth-promoting synaptic communication between GABAergic neurons and H3K27M+ DMG cells 📍Learn more: www.ebraincase.com/support/lite... www.nature.com/articles/s41... #Neuroscience #BrainCancerResearch #Glioma #BrainCaseBiotech

🎉We’re excited to introduce our advanced research service: Whole-Brain Clearing Imaging & Analysis🧠 Click the link to explore full details 📍 www.ebraincase.com/news/corpora... Researchers with related needs are warmly welcome to get in touch with us! 📩[email protected] #Neuroscience #BrainImaging

🔬This study visualizes the full sympathetic and parasympathetic innervation of the mouse lacrimal gland and reveals a key gatekeeping role of the LC–SCG–LG axis in regulating reflex tear secretion 🧠Tool viruses from Brain Case Biotech www.ebraincase.com/support/cust... #Neuroscience#DryEyeResearch

🎉Client Publication Sour stimulation reduces liver IRI via the brain–liver axis (TAFA2–CCR2 pathway), proven in both mice and humans. Published in J. Hepatol.(IF=33) by Tongji Hospital team. 🔬 Vectors by Brain Case Biotech | [email protected] www.ebraincase.com/support/cust... #LiverResearch #TAFA2

Congrats to Prof. Bi, Prof. Liu&team on their Cell paper!🎉With blockface-VISoR, they achieved subcellular 3D mapping of the whole-mouse nervous system.Proud to support this work with Brain Case Biotech’s viral tools! www.ebraincase.com/support/cust... #Neuroscience #blockfaceVISoR #BrainCaseBiotech

🔁Sharing a Client Success! Thrilled to see our partners publish their latest #research in Cell, unveiling a whole- #brain projection atlas of prefrontal cortex #neurons in macaques🧠✨ 🔬 Proud that viral tools used in this breakthrough came from Brain Case Biotech! www.ebraincase.com/support/cust...

🔬Explore our cutting-edge service combining neural circuit tracing, spatial transcriptomics, and neuronal subtype analysis—empowering researchers to decode brain connectivity and cell identity with precision. 🧠 📍 www.ebraincase.com/news/corpora... #Neuroscience #SpatialOmics #AAV #BrainResearch

🧠Customer article Sharing ✨ New study reveals how social status and sex shape #METH addiction via distinct dopamine pathways. Females show high vulnerability regardless of rank. Viral tools used are available from Brain Case Biotech. 📍 www.ebraincase.com/support/cust... #Neuroscience #Addiction

✨🧠Two new Neuron studies unveil enhancer AAV tools that precisely target cortical and striatal neurons in rodents and primates—empowering neural circuit research and gene therapy. 🔗 Learn more: 👉 www.cell.com/neuron/abstr... 👉 www.ebraincase.com/support/lite... #Neuroscience #AAV #GeneTherapy

New Cell study reveals that the meningeal lymphatics–microglia axis regulates synaptic balance and cognition via IL-6. Enhancing lymphatic function in aged mice restores memory and inhibitory signaling—offering a new target for #neurodegenerative therapy. www.ebraincase.com/support/lite...

🎉Customer article~ Fudan University researchers identify two distinct #neuron subtypes—CB⁺and PV⁺—in the medial mammillary body (MM).These neurons form parallel,non-overlapping #circuits and play differential roles in behavior,such as motor regulation and aversion. www.ebraincase.com/support/cust...

🚨 New Arrival Alert! Introducing PRV803 – a high-brightness red PRV virus optimized for peripheral nervous system tracing. Enhanced fluorescence, no need for amplification. Fast, clear, and reliable. 👉 Learn more: www.ebraincase.com/news/new-pro... #PRV803 #Neuroscience #NeuralTracing #BrianCase

📢Client #Publication Spotlight This study reveals how microglia-derived IL-6 induces astrocyte apoptosis in the hippocampus, driving anxiety- and #depression- like behaviors in a CSDS model. 🔗 www.ebraincase.com/support/cust... #Neuroscience #DepressionResearch #Microglia #Astrocyte #IL6 #P2X7R

🧠Customer article sharing|Why do some animals keep running,while others quickly adapt? A new #Neuron study from Liping Wang & Xuemei Liu’s team at SIAT uncovers two distinct #neural pathways behind fear response habituation to repeated looming stimuli. 📖Read more: www.ebraincase.com/support/cust...

🔬 SUMMER PROMOTION 2025 | Brain Case Biotech Unlock Exclusive Savings on #ViralVectors & Custom Services — Limited Time Only! ✨ Get 15% OFF #AAV serotypes (AAV5, AAV8, AAV9, Retro, PHP.eB) ✅ 10% OFF #RV, #HSV & #PRV 🎁 Up to 30% OFF custom AAV packaging fees www.ebraincase.com/news/corpora...

🧠 Customer Article Spotlight | #ScienceAdvances! Siyu Zhang and Min Xu systematically reveal for the first time the whole-brain connectivity maps of two #BFCN subtypes: BFCN→ACA (anterior cingulate cortex) and BFCN→BLA (basolateral amygdala). www.ebraincase.com/support/cust... #Neuroscience #AAV