Raphael Mangione (@raphaelmngn.bsky.social)

🐣 What comes first — R-loops or genome instability? There’s now a Behind the Paper to go with our recent study on the interplay between R-loops and DNA damage — with some context, backstory, and the chicken-and-egg question at its core. Check it out 👉 go.nature.com/4ldXbJm

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R-loops and Genetic Instability: a Chicken and Egg Problem Investigating the relationships between R-loops and genetic instability led to the discovery that some DNA:RNA hybrids actually arise as a consequence of DNA lesions. https://go.nature.com/4ldXbJm

about 1 year ago