Excited to share our latest work - expressing the bacterial sodium channel in fly Kenyon cells surprisingly *decreases* their excitability, thanks partly to decreased endogenous sodium channels. This prevents learning and decreases odor-evoked calcium influx doi.org/10.1113/JP28...

Congrats, Eyal! A great way to start.

✨😀Congratulations to postdocs Eyal Rozenfeld and Francesco Limone on being named 2025 Leon Levy Scholars by The New York Academy of Sciences! @sciencelemon92.bsky.social @eyalrozenfeld.bsky.social @moccalin.bsky.social @liddelowsa.bsky.social www.nyas.org/press-releas...

1/ Check out our Juila Manoim, Tal Camchy, @eyalrozenfeld.bsky.social, Hadas Lerner, Hao-Hsin Chang, Ran Darshan, and Ya-Hui Chou new study in @currentbiology.bsky.social. www.sciencedirect.com/science/arti...

I started my lab more then 4 years ago, and we have endured some very challenging times ever since.…I am very excited to share the first paper from my lab, published now in @naturemethods.bsky.social www.nature.com/articles/s41...

Our story about flies on carousels is out in @currentbiology.bsky.social! After formally engaging the fantastic @clarahowcroft.bsky.social and integrating helpful reviewer feedback, we present a more concise story with detailed behavioural quantification and cooler videos! doi.org/10.1016/j.cu...

So happy to see this paper out! Congrats @victoriacorbit.bsky.social and @ahmarilab.bsky.social! Lots of fond memories from running these experiments. The similarity in the behavioral and striatal neural response time course produced by driving M2 inputs was really striking.

An early surge of norepinephrine along brainstem pathways drives sensory-evoked awakening www.biorxiv.org/content/10.1... Happy to see this great work (and some PdCO application) out in the wild.

Marlin Lab’s 1st Thesis Defense ✨ Hear the science @2:30pm EST bit.ly/MarlinLab Have the cheers @5:00 pm EST JLG✨ Columbia Biology student Beka Stecky will share her discoveries on “What the Nose, Knows” after learning an odor predicts a stressful experience.👃🏽🧬🧪

1/ The choroid plexus (ChP) isn’t just a CSF producer. It’s a dynamic interface between the brain and body, playing key roles in immune regulation, maintaining the blood-CSF barrier, and secreting signaling molecules critical for CNS health.

My thesis defense date is official! And yes I put my cat and Tac2 neurons on my poster 🥰

Antipsychotics is often used to suppress hyper-aggression. Does it really suppress aggression or just cause sedation? Antipsychotics targets dopamine receptors. Our new study revealed that dopamine modulates aggression based on animals' fighting experience. www.nature.com/articles/s41...

Fly neuro people: has anyone tried the Ting lab’s scFLARE (or variants) for labelling active neurons in Drosophila? Thanks.

🚨Postdoc and Postbac positions available in my group at the NIEHS/NIH! Interested in investigating the neural mechanisms for social behaviors across development in a supportive environment? Make sure to apply! Job ads in🧵Feel free to DM/email w/ questions, please RT

We are hiring! We are looking for two PhD students interested in the regulation of habit formation. Habits are useful to decrease cognitive load, but carry the risk of becoming stereotyped and hard to control - it’s hard to shake a bad habit. The fruit fly Drosophila also forms habits and we […]

New year new work from the lab! We explore whether aggression experience and observation lead to similar changes in future aggression strategy. (They do!) We perform 2-color imaging across the whole social behavior network across time and track changes www.biorxiv.org/content/10.1...

(1/6) Excited to introduce our first generation red acetylcholine sensors! #acetylcholine #GRAB #RedSensors www.biorxiv.org/content/10.1...

🎄PinkyCaMP- our christmas gift to you! 🎁: We are excited to present PinkyCaMP, the first mScarlet based calcium sensor with: ✨exceptional, brightness ✨phototability ✨and optogenetic compatability. Check out our new preprint: www.biorxiv.org/content/10.1...

Apropos of never ending discussions about whether ANNs are "good" models of the nervous system, here is a slide I present to masters students showing a network that is found in motor control circuits *across phyla* (that's pretty ubiquitous!) I ask them to guess what it does...

Why not joining us?

Wanna switch on/off synaptic transmission but not the ideal vector for your🧠🧪🔬, we are happy to help! Requested recently & available to you: ChrimsonR(no soma targeting)+PdCO (Cre & non-Cre) DoxOn/OFF PdCO-EGFP (TREtight) -> docs.google.com/spreadsheets... Probably soon @addgene.bsky.social too.

Sex or survival—what’s more important? Excited to share our @Nature paper on how flies resolve this conflict. We found a dopamine-based filter that reduces threat perception, helping flies focus on courtship when close to mating. www.nature.com/articles/s41...

Hi everyone! I am Daniela, a pre-clinical psychedelic researcher doing a PhD at the Paris Brain Institute under the supervision of Eric Burguière. I am working with the SAPAP3-KO mice and LSD. I am a great advocate for open science, diversity and science communication! Nice to meet you all 🥰

Neuroscience students asked us to teach a PRACTICAL course on experimental methods, and it is now on YouTube! Please like and repost to help us get the word out! www.youtube.com/playlist?lis... Lecture 1: Signals and data acquisition Focusing on hardware, digital/analog I/O, synchronization 🧵

I made the Insect Sensory Neuro starter pack - let me know in the comments if you'd like to be added! (and also I'm sure I missed tons of people - tag them in!) go.bsky.app/JW7c5LN

Excited to have this paper out (rdcu.be/d0T3Y)! In it, we focused on how flies know what to attend to in a complex environment (like below)? We uncovered neuronal pathways through which social states (like aggression 🥊) modulate visual processing in #Drosophila. #WomenInSTEM #neuroscience 🧪 1/

It was nice to take a break from project-related OFC/amygdala papers & read a fun fly study from the Parnas lab this morning: www.science.org/doi/full/10.... Exciting to see potentially distinct pathways for cue- & action- outcome learning in the fly, drawing parallels between the MB & striatum.

Everyone knows that failure is bad. We devote a lot of time to trying to avoid it. But sometimes failure is good. A brief story: ~11 yrs ago, when my friends were all starting their own labs, I was starting my 2nd postdoc. My 1st postdoc (w/ Gord Fishell at NYU) had ended in disaster when 1/

1/ 🧠 Ever wondered how different types of learning coexist in our brains? Spoiler: Sometimes, they don’t! Our new study flips the script on what we thought about memory and learning in Drosophila. Dive in for a surprising twist! 🧵👇 www.science.org/doi/10.1126/...

1/ How do animals integrate different forms of learning? Our @eyalrozenfeld.bsky.social new study in Science Advances shows that active mechanisms prevent the co-formation of competing memories. Here’s what we found! 🧵👇 science.org/doi/10.1126/...

Very cool work: interfere between classic and operant conditioning!

1/ 🧠 Ever wondered how different types of learning coexist in our brains? Spoiler: Sometimes, they don’t! Our new study flips the script on what we thought about memory and learning in Drosophila. Dive in for a surprising twist! 🧵👇 www.science.org/doi/10.1126/...

This exciting new paper about the neural mechanisms underlying classical and operant learning in flies 🪰 is finally out - it matters which paradigm you use to test your animals!

New from Shiko Parnas' lab: Classical & operant learning in *Drosophila* rely on distinct neuronal pathways, challenging current paradigms! Unstoppable www.science.org/doi/10.1126/...

Thanks Stories of Win! It felt really great to be able to gush about the lab and the people who have made it so awesome. 😊

Check out our latest profile! Dr. Annegret Falkner (@neurrriot.bsky.social) studies how social experiences and internal states shape behavior. To learn more & listen to the full interview, follow the link below! www.storiesofwin.org/profiles/202... #StoriesOfWiN #WomenInNeuroscience #WomenInNeuro

Every intro to neuroscience textbook features voltage gated sodium channels, but did you know that #GPCRs are also voltage dependent? In our @natureportfolio.bsky.social paper we found that GPCR voltage dependency controls neuronal plasticity and behavior. www.nature.com/articles/s41...

In our paper @currentbiology.bsky.social we uncover the tactile & afferent mechanisms of the rat pup transport response. Teamwork ✋ Zheyi, Connor, Arturo, Marta, Yu, Michael @sidb-edinburgh.bsky.social @edinunineuro.bsky.social @mblscience.bsky.social Read the dispatch too! tinyurl.com/4ez3k9uw

Could one envision a synthetic receptor technology that is fully programmable, able to detect diverse extracellular antigens – both soluble and cell-attached – and convert that recognition into a wide range of intracellular responses, from gene expression and real-time fluorescence to modulation..

here are only 38 patch-clampers on this plattform!?! Who else? 🧠 🔬 🧪 go.bsky.app/RuCRCgX

Many people have asked me what's the deal with "SIO" in our Addgene vectors (www.addgene.org/Ofer_Yizhar/) - we use these in most of our Cre-dependent AAVs - so here's a brief explanation of how it works.

Flies raised in isolation develop fear of their peers, but exposure to others helps them regain sociability. Cool research from the Ramdya Lab! www.biorxiv.org/content/10.1....

How to rebuild your network on @bsky.app and improve your experience here? I made a short starter guide with resources. www.neuronaldynamics.eu/resources/bl... Also, a thread 🧵 below.

1/✨ New paper in #eNeuro! We looked at how dominance behaviors vary across mouse strains—turns out, it’s not one-size-fits-all! Comparing CD1 & C57 male mice, we found strain-specific dominance behaviors that could change how we study social hierarchy in the lab…🧵 Paper here: tinyurl.com/bdeuf6s9

Since insecticides aren’t allowed in the fly lab, we've accidentally created a tiny 'fly management' ecosystem. Nature’s got our back... or maybe it's just a new reality show: Survivor: Fly Edition.

First post on Bluesky! New collaborative study from Quentin Gaudry and I, led by Dr. Ahana Mallick on the role of 5-HT in modulating critical period plasticity in the antennal lobe of Drosophila. Enjoy! www.sciencedirect.com/science/arti...

Psyched that my postdoc work w @markbrandonlab.bsky.social + @atkeinath.bsky.social is now in Neuron! TL/DR: remapping in CA1 has a representational structure that is reliable across brains, and we use this representation to test models of cognitive maps. #NeuroSky #NeuroAI 🧪🧠 tinyurl.com/4juhmad8

They figured out how “love blindness” in flies work. What’s next? Be part of it. www.nature.com/articles/s41...

Announcing a new open access textbook for entry level behavioral neuro. Funded by NSF. Written by a collection of 26 neuro experts. Method demonstration videos and author interviews too. Consider using it in your courses to reduce financial barriers to education. openstax.org/details/book...

🌟 Cai Lab Nature (@natureportfolio.bsky.social) paper alert! In work led by Joe Zaki, we find that rest periods after learning not only stabilize new memories BUT ALSO integrate new memories with older ones from days past! (1/10) Read it here: www.nature.com/articles/s41...